EUVIMEDEuropean Health Evidence
Uhr 7/7Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Medizin · Seite 11

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Oncology

Sequencing immunotherapy in locally advanced head and neck squamous cell carcinoma: a narrative clinical-translational review

Ruey-Long Hong

Background Immune checkpoint inhibitors have entered curative-intent treatment of locally advanced head and neck squamous cell carcinoma, but randomized trials have shown divergent results across definitive, perioperative, and postoperative settings. Methods We reviewed pivotal randomized phase II–III trials and key translational studies to examine how treatment sequence relative to radiation and surgery, together with anatomic context, influences efficacy. Results Concurrent immunotherapy with definitive chemoradi …

03.09.2026journal-article

Multidisciplinary Respiratory Medicine

Peri-procedural code status discussions before bronchoscopy: a cross-sectional survey of German and Swiss pulmonologists

Flavio Gössi, Armon Arpagaus, Benjamin Bissmann, Samuel Kaspar Zumbrunn, Thierry Girard, Jürgen Hetzel, Kathleen Jahn, Katrin E Hostettler, Sabina Hunziker

Introduction: In-hospital cardiac arrest is associated with poor outcomes, yet peri-procedural code status discussions before bronchoscopy may be inconsistent, particularly in patients with elevated procedural risk. Methods: We conducted an anonymous online survey of a convenience sample of hospital-based pulmonologists in Germany and Switzerland between April and July 2025. The survey assessed routine practices and attitudes regarding peri-procedural code status discussions, risk stratification, and management of …

03.09.2026journal-article

Current Pediatrics

Demographic Window of Opportunities: Clinical and Economic Justification of HPV Vaccination Inclusion in NIS in 2027

Leyla S. Namazova-Baranova, Marina V. Fedoseenko

Human papillomavirus (HPV) infection is highly contagious and is the most common sexually transmitted infection. It causes irreversible damage to human reproductive health, leading to benign and malignant neoplasms in anogenital and other areas. Cervical cancer continues to have the leading position in mortality among young women of reproductive age. The key tool in combating HPV infection is primary prevention, vaccination; furthermore, the implementation of the Global Strategy for HPV vaccination will prevent up …

03.09.2026journal-article

Academic Medicine

Translation of alcohol research to the academic medicine community

George F Koob

Abstract The goal of alcohol research is to improve overall health and well-being. Alcohol misuse causes an estimated 178,000 deaths annually in the United States, involves over 4 million emergency room visits annually, and contributes to or exacerbates 200 medical disorders and conditions. Reducing and preventing the pathology and other consequences of alcohol misuse can significantly reduce morbidity and mortality. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) was created in 1970 in response to n …

03.09.2026journal-article

Diagnosis

History taking: the foundation of diagnostic excellence

Stephen W. Russell, Brian T. Garibaldi, Doug Salvador

Abstract Medical history taking serves a critical role in improving diagnostic safety and patient outcomes. Despite advances in technology, a patient’s medical history remains the cornerstone of accurate diagnosis, often yielding diagnoses before tests are performed. This article explores how patient-centered communication, contextual awareness, and evidence-based strategies reduce diagnostic errors, which often stem from miscommunication during the clinical encounter. It highlights practical tools for clinicians a …

03.09.2026journal-article

Interactions

Predictive analysis of wear rate in SUP9 spring steel under controlled heat treatment cooling rates

Mamookho Elizabeth Makhatha, Sergei Sherbakov, Daria Podgayskaya, Pawan Kumar

Abstract In the present work, SUP9 spring steel specimens were reheated to 1000 °C in a controlled muffle furnace to obtain a homogeneous austenitic structure. The specimens were then cooled at different rates (0.1, 5, 100, 375, and 650 °C) to generate varied microstructures. Increasing the cooling rate refined the pearlitic microstructure, resulting in a finer and more uniform grain structure. These heat-treated specimens were then subjected to the wear test to study the influence of cooling rate ( dT/dt ), load ( …

03.09.2026journal-article

Frontiers in Medicine

Preliminary exploration of the value of pericoronary adipose tissue radiomics in identifying high-risk patients with chronic coronary syndrome: a retrospective Chinese cohort study

Zhang Ludan, Chen Chen, Zhang Yu, Hou Hui, Wang Zewen, Xia Xiaofeng, Luo Xiangwei, Zeng Yan, Chen Jianzhou

Background Chronic coronary syndrome (CCS) requires accurate risk stratification for optimized management. Pericoronary adipose tissue (PCAT) inflammation is closely associated with plaque progression, and coronary computed tomography angiography (CCTA)-based radiomics may provide information beyond the traditional fat attenuation index (FAI). Objective To assess the value of PCAT radiomics and its combination with one-stop CCTA parameters for identifying CCS patients who are classified as high-risk by the 2024 Eur …

03.09.2026journal-article

Frontiers in Medicine

Prevalence of financial toxicity and construction of a risk prediction model for lung cancer patients at 6 months after discharge

Ningning Liu, Xiaoyan Wang, Xiaofeng Pan, Caifang Tang, Ximiao Li, Yiting Zhang, Yaru Zhao

Objective To investigate the prevalence of 6-month post-discharge financial toxicity in lung cancer patients, identify its independent predictors, and establish a valid risk prediction model integrating socioeconomic, clinical, and patient-reported outcome variables as baseline predictors, so as to support early financial toxicity screening, targeted financial counseling and standardized nurse-led stratified transitional nursing interventions. Methods A single-center prospective cohort study enrolled 682 hospitaliz …

03.09.2026journal-article

Journal of Patient-Reported Outcomes

Comparing statistically reliable and patient-perceived improvement following hip arthroplasty: Rasch-based and anchor-based approaches

Adam B. Smith, Stuart Mealing, Damian Lewis, Andria Joseph

Abstract Background Interpreting meaningful change in patient-reported outcome measures (PROMs) is essential for assessing hip replacement outcomes. The Oxford Hip Score (OHS) is widely used, yet statistically detectable change may not align with patient-perceived improvement. Objectives To compare Rasch-based classifications of OHS change, following Hobart’s effect size methodology, with anchor-based interpretations derived from patient Global Impression of Change (GIC). Methods OHS data from a large hip replaceme …

03.09.2026journal-article

Frontiers in Medicine

Fractal analysis of peri-implant trabecular bone complexity following transcrestal sinus floor elevation: a retrospective radiographic study

Irfan Ustundag, Sevval Ilkyaz, Numan Dedeoglu, Selman Bolukbasi, Mehmet Sait Simsek, Yunus Çetiner, Bahadir Sancar

Background This retrospective radiographic study aimed to evaluate time- and region-dependent changes in peri-implant trabecular bone structural complexity using fractal dimension analysis after transcrestal sinus floor elevation (TSFE) with 3, 4, or 5 mm sinus membrane elevation. Methods A total of 45 dental implants placed simultaneously with TSFE in 35 patients were categorized into three groups according to sinus membrane elevation height (3 mm, 4 mm, and 5 mm). Fractal dimension analysis was performed using Im …

03.09.2026journal-article

Annals of Surgery

The Impact of Anastomotic Leak After Esophagectomy on Long-term Survival in the Modern Era of Management (ALES Study)

Lorenzo Giorgi, Nadia Guidozzi, Riadh Salem, Wing K. Chou, Stijn Vanstraelen, Helena Gielen, Johnny Moons, Philippe Nafteux, Femke E. Lammes, Jelle P. Ruurda, Richard van Hillegersberg, Alban Todesco, Xavier Benoit D’Journo, Alice Collizzolli, Barbara Ajazi, Simone Giacopuzzi, Maria Bencivenga, Sam Alhayo, Ella Seabourne, Ewen A. Griffiths, Aram Abu Hejleh, Lars M. Schiffmann, Christiane J. Bruns, Giovanni Maria Garbarino, Andrea Pansa, Silvia Basato, Ophélie Bacoeur-Ouzillou, Caroline Gronnier, Sofie P. G. Henckens, Suzanne S. Gisbertz, Rakesh Ahmed, Nithiesh Loganathan, Jessie A. Elliott, Kirsty Cole, Youssef Ibrahim, Chanakya Anand, Philip H. Pucher, Martin Skogar, Jakob Hedberg, Eloise Bonnin

Objective: To determine the impact of severity of esophageal anastomotic leak (AL), standardized by ECCG grading, on long-term survival within a contemporary multicenter cohort. Summary Background data: Historical evidence suggesting AL is associated with increased recurrence and poor survival is limited by heterogeneous definitions and outdated management. This study utilizes the standardized ECCG definition to evaluate the prognostic significance of AL severity under modern perioperative protocols and endoscopic …

03.09.2026journal-article

Petroleum Engineering

ANALYSIS OF THE EFFECTIVENESS OF STEAM TREATMENT DURING CYCLIC STEAM SIMULATED

Yu.E. Mikhailova, D.Yu. Savrey, V.V. Durkin

Cyclic steam simulated (CSS) is the most common technology of thermal impacton the formation of high-viscosity oil. The CSS technology is the injection of steam into a well, followed by the soaking stage (stopping the injection of steam to condense), followed by switching to the operating mode of the producing well. After the production wells are put into operation, production is carried out to a certain level of water cut floating oil or a cost-effective flow rate. The duration of the effect of the CSS can be both …

03.09.2026journal-article

Archives of Orthopaedic and Trauma Surgery

Early surgery of trochanteric femoral fractures in patients on direct oral anticoagulants (DOACs) reduces the length of stay (LOS) and the 1-year mortality rates without increasing the risk for revision surgery: a matched-pair analysis

Valerie Weihs, Roberta Laggner, Michael Humenberger, Andreas Duma, Martin Frossard, Stefan Hajdu

Abstract Background It remains unclear whether early surgical fixation of trochanteric femoral fractures in patients with direct oral anticoagulation (DOAC) therapy has an impact on the long-term outcome. Methods A retrospective cohort study on patients with trochanteric femoral fractures and DOAC therapy between 2016 and 2024 was conducted. Patients were divided into two groups according to their time to surgery and matched with age and ASA score as covariates. The primary outcome of interest was the impact of ear …

03.09.2026journal-article

Viruses

Pediatric Arboviral Infections in Europe: Epidemiology, Clinical Features, Diagnosis and Prevention

Giulia Sturniolo, Silvia Garattini, Denis Doni, Marco Zacchello, Diletta Zanetti, Sofia Galzignato, Andrea Lo Vecchio, Vincenzo Baldo, Daniele Donà

Arboviral infections, including West Nile virus (WNV), dengue virus (DENV), chikungunya virus (CHIKV), Zika virus (ZIKV), and, to a lesser extent, Oropouche virus (OROV), pose a heterogeneous and evolving challenge for pediatric health in Europe. The increasing presence of competent vectors and international travel has resulted in both imported infections and, for selected arboviruses, documented autochthonous transmission events. Although pediatric cases are often underrecognized, children may develop severe manif …

03.09.2026journal-article

Frontiers in Pharmacology

Suspected NIUAA after indobufen in a patient with ibuprofen allergy: a case report suggesting possible cross-reactivity

Long Luo, Jun Li, Ying Yuan, Ling Zhu

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in clinical practice, and hypersensitivity reactions to them are not uncommon. Although ibuprofen and indobufen have different clinical indications, both exert their effects through cyclooxygenase inhibition, suggesting a potential risk of cross-reactivity. This report describes a 52-year-old female patient who experienced pruritus, facial and eyelid edema, tearing, and ocular itching approximately half an hour after two separate exposures to ibuprofe …

03.09.2026journal-article

Clinical Kidney Journal

Hypophosphatemia after CAR-T cell therapy: a prospective study of inflammation, tubular injury and phosphate handling

F Moncho-Francés, R Hernani, MA Solis-Salguero, A Benzaquén, I Juan-García, A Pérez-Martínez, M Micó, JF Navarro-González, JL Piñana, JC Hernández-Boluda, MJ Terol, C Solano, JL Górriz, I Torregrosa

Abstract Background Hypophosphatemia is a frequent electrolyte abnormality after chimeric antigen receptor T-cell (CAR-T) therapy, but the clinical and biological factors associated with phosphate decline remain poorly defined. We prospectively evaluated the incidence, determinants and potential biological associations of hypophosphatemia after CAR-T therapy. Methods We conducted a prospective study including 63 adults with B-cell lymphoma treated with CAR-T therapy between June 2020 and December 2023. Serum phosph …

03.09.2026journal-article

Physics in Medicine & Biology

A real-time image-guided six-degree-of-freedom internal-external correlation framework for motion monitoring on a standard linear accelerator

Alicja Kaczynska, Freeman Jin, Maegan Stewart, John Kipritidis, Jeremy Booth, Nicholas Hardcastle, Paul Keall, Chandrima Sengupta

Abstract Objective. Real-time six-degree-of-freedom (6DoF) tumour motion monitoring is important for accurate stereotactic body radiotherapy (SBRT) of thoracic and abdominal cancer sites, yet existing approaches either require specialised imaging hardware or continuous fluoroscopic imaging. This study presents the development and first experimental implementation of a real-time image-guided 6DoF internal-external correlation (6D-IEC) modelling framework on a standard linear accelerator. Approach. The 6D-IEC framewo …

03.09.2026journal-article

Head and Neck Pathology

Pattern-Anchored Diagnosis of Oral Epithelial Dysplasia: A Position Paper From COST Action INTERCEPTOR Working Group 2

Syed Ali Khurram, Keith D. Hunter, Edward W. Odell, Merva Soluk Tekkeşin, Mark Lingen, Pablo Agustín Vargas, Omar Kujan, Daniela Elena Costea, Paolo Bossi, Pierre Saintigny, Senada Koljenović

Abstract Purpose Oral epithelial dysplasia (OED) is the principal histopathological marker for malignant risk stratification in oral potentially malignant disorders (OPMDs). Current World Health Organisation (WHO) three-tier and other binary grading systems are limited by modest inter-observer reproducibility and suboptimal prognostic discrimination, particularly for architecture-predominant lesions where cytological atypia is inconspicuous. The most clinically consequential failure of current practice is not mis-g …

03.09.2026journal-article

European Journal of Nuclear Medicine and Molecular Imaging

CEA-targeted fluorescence endoscopy for the detection of high-grade dysplasia and early invasive rectal cancer: A proof-of-concept trial

M. I. Warmerdam, T. H. Dijkhuis, D. J. G. Linders, C. M. W. Pesch, A. S. L. P. Crobach, A. Matoshi, K. Basiliya, S. H. van den Berg, F. Cailler, K. C. M. J. Peeters, F. A. Holman, J. S. D. Mieog, A. L. Vahrmeijer, D. E. Hilling, J. J. Boonstra

Abstract Purpose Accurate recognition of high-grade dysplasia (HGD) and early invasive carcinoma (IC) within colorectal polyps is essential for selecting the preferred local resection technique. However, optical endoscopic diagnosis can be challenging, particularly in large and advanced polyps. This study investigates whether carcinoembryonic antigen (CEA)-targeted near-infrared fluorescence (NIRF) imaging can distinguish polyps containing HGD/IC from polyps solely containing low-grade dysplasia (LGD), given prior …

03.09.2026journal-article

Frontiers in Oncology

Risk factors, severity-related factors, and clinical outcomes of immune checkpoint inhibitor-associated pneumonitis in elderly patients with lung cancer

Ying Hu, Shuhua Chen, Yingying Lu, Lingjuan Yang

Objective This study aimed to investigate the clinical characteristics, risk factors, severity-related factors, and clinical outcomes of immune checkpoint inhibitor-associated pneumonitis (CIP) after immune checkpoint inhibitor (ICI) treatment in elderly patients with lung cancer, providing evidence for risk identification and nursing management during ICI therapy. Methods Clinical data from 206 elderly patients with lung cancer who received ICI therapy at the Second Affiliated Hospital of Naval Medical University …

03.09.2026journal-article

Frontiers in Cellular and Infection Microbiology

Multidisciplinary management of severe odontogenic maxillofacial multi-space infection in a patient with HIV–syphilis coinfection and advanced immunosuppression: a case report

Jieying Li, Yuanyong Feng, Xueqiang Guo, Wei Shang, Kai Zhou

Background HIV–syphilis coinfection poses a substantial challenge in the management of severe odontogenic infections, with few reports addressing maxillofacial multi-space infections in this setting. Case presentation A 50-year-old man developed severe left maxillofacial multi-space infection one week after molar extraction, presenting with respiratory distress, trismus, elevated C-reactive protein (235.20 mg/L), computed tomography evidence of gas-forming abscesses, reactive HIV antibody, positive syphilis serolog …

03.09.2026journal-article

Journal of Clinical Medicine

Reference Estimates of Mean Tear Film Lipid Layer Thickness Measured with LipiView® and LipiView II® in Healthy Adults: A Systematic Review and Meta-Analysis

Maria Sobol, Jacek Pniewski

Background/Objectives: Tear film lipid layer thickness (LLT) is an important parameter of ocular surface function and can be objectively measured using LipiView ocular surface interferometry. However, reference LLT estimates in clinically healthy populations remain inconsistent. This systematic review and meta-analysis aimed to estimate pooled reference LLT values and explore potential sources of variability. Methods: A systematic search of PubMed, Scopus, and Web of Science was performed according to PRISMA 2020 g …

03.09.2026journal-article

Indian Journal of Nuclear Medicine

A Resource-Efficient End-to-End Multimodal AI Framework for Automated PET-CT Report Generation and TNM Staging in Breast Cancer

Dibya Prakash, Venkatesh Rangarajan, Manoj Kumar

Objectives: Positron Emission Tomography-Computed Tomography (PET-CT) is integral to breast cancer staging. However, manual interpretation is time-consuming and subject to inter-observer variability. While artificial intelligence has shown promise in lesion detection and standardised uptake value (SUVmax) quantification, existing approaches are fragmented and do not generate complete TNM-aligned structured reports. Consequently, there remains a need for an integrated framework capable of translating PET-CT data int …

03.09.2026journal-article

Frontiers in Surgery

Early outcomes following Duramesh™ implantation for abdominal wall closure: the Croydon experience

Lawrence Nip, Sarah Zhao, Sajid Malik, Reif Hwang, Jessica Quimpo, Eslam Ghazy, Matt Dunstan, Rhys Thomas, Samuel G. Parker

Introduction Mesh suture, or Duramesh™, is gaining traction for abdominal wall closure and ventral hernia repair. However, published data are limited to US case series and institutional registries. Use in UK and European cohorts remains undocumented. This is the first UK series describing indications and outcomes following Duramesh implantation. Methods This is a retrospective case series from a medium-sized tertiary abdominal wall unit in the UK. Institutional implant logs of consecutive patients from 1st Sep 2023 …