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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

IECCMEXICO

Optimizing Elective Surgical Access: Integrated Strategies for Waiting-List Prioritization, Efficiency, Equity, and Clinical Outcomes

Valeria Hidalgo Figueroa, Susana María López Rojas, Keren Abigail Saynes Jarquin, Ana Carla Naranjo González, Pedro Aníbal Bailón de la O, Jaime Héctor Cisneros Sandoval, Blas David Santana Perez, Martín Ham San Martín

Surgical waiting lists represent a major challenge for healthcare systems because prolonged delays can affect not only service efficiency but also patient function, quality of life, equity of access, and clinical outcomes. This study analyzed the principal strategies used to manage elective surgical waiting lists, with emphasis on patient prioritization, referral management, cancellation prevention, perioperative efficiency, and dynamic reassessment. A structured review of the literature was conducted using evidenc …

02.09.2026journal-article

Orthopaedic Surgery

Global Alignment and Proportion ( GAP ) Score in Predicting Mechanical Complications After Long‐Segment Fixation for Chinese Geriatric Patients With Adult Degenerative Scoliosis: A Mid‐Term Comparative Study

Xiangyao Sun, Jiang Huang, Yuqi Liu, Siyuan Sun, Li Cao, Juyong Wang, Shibao Lu

ABSTRACT Objectives The predictive value of the global alignment and proportion (GAP) score in the Chinese geriatric population, which has unique demographic and degenerative characteristics, has not been validated. Given the high incidence of mechanical complications in this specific cohort, a dedicated mid‐term evaluation is essential to guide surgical planning. To address this gap, this study aimed to analyze the accuracy and characteristics of the GAP assessment system in predicting mechanical complications fol …

02.09.2026journal-article

UAEU Law Journal

ضوابط استخدام تقنية النانو في المجال الطبي: دراسة تأصيلية

حبيبة يوسف جاما علي, محمد سليمان النور

تقوم الدراسة حول بيان مفهوم تقنية النانو وتطبيقاتها الطبية المعاصرة، وما تنطوي عليه هذه التقنية من مصالح ومفاسد، كما تهدفُ إلى توظيف النظر الاجتهادي في المسألة بالاستهداء بالأدلة العامة، والمقاصد الشرعية، والقواعد الفقهيّة تمهيدًا لبيان الحكم الشرعي في المسألة.وقد اتبعتُ في هذا البحث المنهج الاستقرائي بتتبع المادة العلمية من مظانها، والمنهج الوصفي لوصف المسألة وفق ما قرره أهل الخبرة والاختصاص، واستعنت بالمنهج التحليلي لتحليل الأدلة والنصوص والنظر في المقاصد الشرعية والقواعد الفقهية؛ لاستنباط الحكم الشرعي للمسألة، و …

02.09.2026journal-article

Clinical Cancer Research

Phase I Trial of IL13Rα2-Targeted CAR T-cell Therapy for Recurrent Malignant Glioma: Clinical Results and Pharmacokinetics

Kiwan Kim, Seong-Won Song, Yeongha Jeon, Soyoung Choi, Jiyoun Choi, Sungmin Jun, Ju-Hwang Park, Song-Jae Lee, Nayoung Han, Yun-Sik Dho, Sang-Hoon Shin, Heon Yoo, Kyu-Chang Wang, Ho-Shin Gwak

Abstract Purpose: This single-center, open-label, phase I trial evaluated the safety and tolerability of chimeric antigen receptor (CAR) T cells targeting interleukin 13 receptor α2 (IL13Rα2) in patients with malignant gliomas. Patients and Methods: Adults with World Health Organization grade 3 to 4 gliomas, recurrent after standard treatment and expressing IL13Rα2 (confirmed by immunohistochemistry), received a single intravenous infusion of autologous CAR T cells. Primary objectives were to measure the maximum to …

02.09.2026journal-article

Journal of Intensive Care Medicine

Comparison of Midline Venous Catheters Versus Peripherally Inserted Central Catheters for Intravenous Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Kumail Mustafa Ali, Hafsa Ahmed, Syeda Fatima Mustafa Zaidi, Talha Khalid, Ahmed Hasan, Urooba Mughal, Ibrahim Zulfiqar Ali, Farida Khan Kakar, Muhammad Hamza, Samina FNU, Rohin Kumar, Suraksha Rani, Tayyaba Uzair, Ahmed Mustafa Rashid

Background Midline venous catheters (MVCs) have been encouraged as alternatives to peripherally inserted central catheters (PICCs) for intermediate to long-term intravenous therapy. However, randomized controlled trials (RCTs) have reported contradictory findings regarding their comparative safety and resilience. We aim to compare MVCs and PICCs in patients receiving intravenous therapy. Methods PubMed/MEDLINE, Embase, Scopus, and the Cochrane Central databases were searched from inception through March 2025. RCTs …

02.09.2026journal-article

Journal of Clinical Medicine

Beyond Binary ICU Admission: Duration-Sensitive Evaluation and Patient-Level Reclassification of Textbook Outcome After Colorectal Cancer Surgery

Adem Ozcan, Gizem Gunes, Ali Bal, Abdulkadir Unsal

Background/Objectives: Textbook outcome (TO) is an all-or-none composite in which a common, practice-sensitive component may exert disproportionate influence on patient classification. We evaluated the classification impact of binary postoperative intensive care unit (ICU) admission and the additional information retained by actual ICU duration after colorectal cancer surgery. Methods: This retrospective single-center cohort included 241 patients undergoing colorectal cancer resection between 2020 and 2026. Compreh …

02.09.2026journal-article

LUMEN ET VIRTUS

MANEJO DA SÍNDROME DE ABSTINÊNCIA ALCOÓLICA GRAVE: ESTRATÉGIAS ATUAIS PARA PREVENÇÃO DE CONVULSÕES E DELIRIUM TREMENS

Laysa Cordeiro Cavalcanti Nunes, Nathália Déo Gasparotto, Matheus Pereira Do Vale, Bruna Bastos Bezerra, Luisa Bastos Bezerra, Gabriella Lara Silva Santos, Heder Albuquerque Azevedo Rocha, Antonio Jose Angulo Mora, Ágata Raposo De Medeiros, Isadora Casagrande Amalcaburio, Maria Eduarda dos Santos Pinto, Amanda Andressa de Souza Carvalho, Eberson da Silva Rodrigues Do Nascimento, Wanuelly Andreza Silva Melo, Vitória Ferreira Alves, Gianluca Homero Rebelo De Souza, Gustavo Fleury Gomes Ferreira, Maria Fernanda Mendes De Andrade, Lucca Corcini Biscaino, Bruna Letícia Olinda Vieira Moreira, Lyvia Rodrigues Parreira Braga, Debora Dias Figueiredo Veloso, Márcio José de Carvalho Lima, Emerson Renê de Souza Cordeiro, Adriel Dias Marinho Da Silva

A síndrome de abstinência alcoólica grave constitui uma emergência clínica potencialmente fatal, sobretudo pela ocorrência de convulsões e delirium tremens. Este estudo teve como objetivo analisar as evidências atuais sobre estratégias de prevenção e manejo dessas complicações em adultos. Realizou-se uma revisão integrativa da literatura, de abordagem qualitativa e caráter clínico-prático, com busca nas bases PubMed/MEDLINE, Scopus, SciELO e ScienceDirect, contemplando estudos publicados entre 2016 e agosto de 2026 …

02.09.2026journal-article

Annals of Surgery

Safety and Performance of the Colovac Anastomosis Protection Device. A Pooled Analysis of Prospective Studies Compared With Diverting Loop Ileostomy (SAFE-2025)

Patricia Sylla, Katherine Lam, Niels Komen, Jean-Jacques Tuech, Antonio Spinelli, Joseph Martz, Rebecca Rhee, Jorge Marcet, Guy Bernard Cadière, Philippe Rouanet, Aleksei Karachun, Quentin Denost, Narkhodzha Sametdinov, Andre D’Hoore, Sang Lee, Jérémie H. Lefèvre

Objective: To compare the safety and effectiveness of the Colovac Anastomosis Protection Device with standard diverting ostomy (DO) following low anterior resection (LAR) for rectal cancer. Summary Background Data: DO is standard of care (SOC) following LAR for rectal cancer but is associated with substantial morbidity. Colovac Device is designed to divert the fecal stream away from the anastomosis intraluminally. Methods: Three prospective multicenter Colovac trials were pooled and compared with a prospective coho …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Prevalence of Parasitic Diseases among Internally Displaced Persons, Ethiopia, 2024

Yohannes Shimelis Masresha, Gizachew Tadesse Wassie, Carolyn Strobel, Francisco Averhoff, Gavin Cloherty, Steven S. Yoon

ABSTRACT. Parasitic diseases remain a major public health concern globally, particularly among vulnerable populations such as internally displaced persons (IDPs), i.e., people who relocate within their own countries due to conflict, natural disasters, or other crises. We assessed the prevalence and associated factors of schistosomiasis, geohelminthiasis, and anemia among IDPs in Ethiopia. We conducted a cross-sectional survey during March and April 2024 among IDPs in camps located in Debre Birhan, Ethiopia. Stool s …

02.09.2026journal-article

Bioinformatics

Identifying expanding TCR clonotypes with a longitudinal Bayesian mixture model and their associations with cancer patient prognosis, metastasis-directed therapy, and VJ gene enrichment

David Swanson, Alexander Sherry, Cara Haymaker, Alexandre Reuben, Chad Tang

Abstract Motivation Examination of T cell receptor (TCR) clonality has become a way of understanding immunologic response to cancer and its interventions in recent years. An aspect of these analyses is determining which receptors expand or contract statistically significantly as a function of an exogenous perturbation such as therapeutic intervention. Results We characterize the commonly used Fisher’s exact test approach for such analyses and propose an alternative formulation that does not necessitate pairwise, wi …

02.09.2026journal-article

Pain Medicine

Does the National Resident Matching Program Rank List Predict Accreditation College of Graduate Medical Education Trainee Performance Among Multispecialty Pain Medicine Fellows? A Multicenter Study

Steven P Cohen, Oludare O Olatoye, Peter Schumaker, Dalia Elmofty, Heejung Choi, Bhavana Yalamuru, Lynn R Kohan

Abstract Background Training programs seek to match fellows who will perform well during training. The National Resident Matching Program (NRMP) allows programs to choose the most capable trainees, with higher ranked applicants expected to perform better. Pain medicine is one of the most popular non-internal medicine fellowships in the U.S., and multiple specialty pathways for entry make selecting candidates challenging. Objective The aim of this study is to correlate fellow rank order and match number with academi …

02.09.2026journal-article

Pure and Applied Chemistry

Development of functional materials for the microplastics removal and treatment in surface water

Fio Febrian, Henny Purwaningsih, Mohammad Khotib

Abstract Microplastics (MPs) are persistent emerging contaminants increasingly detected in aquatic environments and pose potential risks to ecosystems and human health. Conventional single-stage removal technologies may be limited by their treatment efficiency and operational costs. This study aimed to develop a sustainable integrated approach for MP removal by combining aluminum chlorohydrate (ACH) coagulation, polyacrylamide (PAM) flocculation, and column adsorption using phosphoric acid (H 3 PO 4 )-activated bio …

02.09.2026journal-article

Journal of Wound Care

Risk factors for pressure ulcer development among adults undergoing surgery: a systematic review

Sadie Badrie, Pinar Avsar, Sherly George, Shijimol Kurian, Zena Moore, Hannah Wilson

Objective: To examine risk factors for pressure ulcer (PU) development among adults undergoing surgery. Method: A total of five electronic databases were searched from inception to March 2024. Study selection, data extraction and quality appraisal were performed by two independent reviewers, using the Crowe Critical Appraisal Tool (CCAT v1.4; Michael Crowe, James Cook University, Australia), with scores ≥75% indicating high methodological quality. Results were categorised and reported as preoperative, intraoperativ …

02.09.2026journal-article

Journal of Clinical Medicine

Considerations in Using Artificial Intelligence to Simulate Orthodontic Treatment for Implant-Prosthetic Purposes

Amelia Smaranda Roșianu, Sanda Mihaela Popescu, Daniel Adrian Târtea, Stelian Mihai Sever Petrescu, Răzvan Mercuț, Marina Olimpia Amărăscu, Mihaela Ionescu, Ionuț Cristian Reşceanu, Alin Gabriel Ionescu

Background/Objectives: Orthodontic treatment planning software with artificial intelligence has been introduced into practice in recent years. They allow the simulation of the results of orthodontic treatment in several scenarios. The aim of the study was to compare the results of a simulated preimplantation orthodontic treatment plan in cases of oral rehabilitation between two software, with three different setups and their evaluation by an orthodontist. Methods: The in silico study included 10 cases of digital mo …

02.09.2026journal-article

Journal of Cancer Research and Clinical Oncology

Knowledge and attitude towards breast and cervical cancer screening among women caregivers of cancer patients: a cross-sectional study from a tertiary cancer centre in India

Mahak Gupta, Akshay Dinesan, Lahari Udyawar, Ashmitha Prasad, Arathi P Rao, Umesh Velu, Ankita Mehta, Jayashree N P, Sharada Mailankody, Shirley Lewis

Abstract Purpose Female informal caregivers, who provide critical support to cancer patients, may face substantial caregiver burden that may adversely affect their participation in preventive healthcare. We aimed to evaluate their knowledge and attitudes toward breast and cervical cancer screening and its correlation with caregiver burden. Methods A cross-sectional study was conducted at a tertiary cancer centre using a structured questionnaire, which assessed demographics, caregiving burden (using the Zarit Burden …

02.09.2026journal-article

Physics in Medicine & Biology

A three-phase poroelastic-scattering model for skull ultrasound transmission and effective porosity inversion

Le Gao, Yue Pan, Zhiqiang Zhang, Weibao Qiu

Abstract Transcranial ultrasound is increasingly used in brain imaging, neuromodulation, and therapy guidance, but its performance is severely degraded by the skull, whose porous and heterogeneous microstructure induces strong attenuation, scattering, and phase distortion in the MHz range. However, skull-induced transmission loss is still commonly handled empirically, and its quantitative relationship to interpretable microstructural descriptors remains poorly established. In this work, we develop a three-phase por …

02.09.2026journal-article

Military Medicine

Sustained War-Related Emergency Department Presentations and Evolving Civilian Injury Patterns During Recurrent Missile-Related Conflict

Yuval Dadon, Amir Nutman, Orit Mazza, Uri Feinstein, Linoy Gabay, Anat Engel

Abstract Introduction Prolonged missile-related conflicts may generate evolving civilian injury patterns and continuing war-related presentations to emergency departments. Although mass casualty incidents receive substantial attention in the disaster medicine literature, less is known regarding how civilian injury profiles and war-related emergency department presentations evolve during recurrent and prolonged conflict conditions. Understanding these changes is important for healthcare preparedness and continuity o …

02.09.2026journal-article

Current Emergency and Hospital Medicine Reports

A Narrative Review of Medetomidine Toxicity: an Update for Emergency Medicine

Anthony Spadaro, Erin D. Wieruszewski, Brandy N. Hernandez, Brandon M. Carius, Brit Long

Abstract Purpose of Review Unregulated opioids often contain various adulterants, such as alpha-2 agonists, benzodiazepines, and stimulants. Medetomidine, an alpha-2 agonist, has emerged in the United States and has been linked to significant toxicity and severe withdrawal symptoms. This narrative review reviews medetomidine toxicity and withdrawal with a focus on management in the acute care setting. Recent Findings There is significant regional variation in the prevalence of secondarily added adulterants, and reg …

02.09.2026journal-article

IECCMEXICO

Patient-Centered Facial and Orofacial Reconstruction After Cutaneous Cancer Resection: Integrating Function, Aesthetics, and Quality of Life

Sandro José Nava Daza, Erick Fernando Flores García, Luis Felipe Espinal Pérez, Oscar Emmanuel Garcia Moreno, Slendy Dayanna Gil Ayala, Diego Clemente Moreno, Gustavo Adrián Pineda Yañez, Cristian Raziel Pacheco Hernandez, Ashley Jesús García Cortes

Facial and orofacial reconstruction following cutaneous oncologic resection represents a complex clinical challenge in which tumor control must be integrated with preservation of function, restoration of facial appearance, and maintenance of quality of life. This study analyzed contemporary reconstructive strategies used after facial skin cancer excision, with emphasis on the relationship between defect characteristics, anatomical location, surgical technique, functional recovery, aesthetic integration, postoperati …

02.09.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Biomechanical and neuromuscular correlates of DaeDo output during successful dominant- and non-dominant-leg taekwondo side kicks: a repeated-measures study

Yijun Liu, Mengyao Jia

Abstract Objective This study aimed to compare temporal, kinematic, kinetic, and support-side neuromuscular characteristics between dominant- and non-dominant-leg Taekwondo side kicks and to examine their associations with DaeDo output during successful scoring trials. Methods Twelve high-level male Taekwondo athletes, all right-leg dominant, performed side kicks with both legs. Three-dimensional kinematics, force-platform data, support-side surface electromyography (EMG), and DaeDo output were recorded simultaneou …

02.09.2026journal-article

Journal of Clinical Medicine

Anatomical and Functional Outcomes of Repeat Vitrectomy Combined with Encircling Scleral Buckling for First Recurrent Rhegmatogenous Retinal Detachment After Primary Vitrectomy: A Retrospective Cohort Study

Georgios D. Panos, Alex Stubbing-Moore, Dharmalingam Kumudhan, Gavin Orr, Anwar Zaman, Craig Wilde

Purpose: The purpose of this study is to evaluate anatomical, visual, and safety outcomes after repeat pars plana vitrectomy combined with 360° encircling scleral buckling for first recurrent rhegmatogenous retinal detachment following primary vitrectomy. Methods: This retrospective single-centre cohort included 47 eyes of 47 patients treated between October 2016 and October 2023. The primary outcome was freedom from any subsequent retinal re-detachment during available follow-up. Secondary outcomes included final …

02.09.2026journal-article

Systems

When AI Joins the Diagnosis: How Doctor–AI Collaboration Shapes Perceived Doctor Responsibility Under Perceived Diagnostic Errors

Ruxia Cheng, Rui Sun, Wenlong Tang

Artificial intelligence (AI), especially generative AI, is becoming deeply embedded in healthcare, making doctor–AI collaborative diagnosis a common mode of medical decision-making. This development raises a critical question about responsibility attribution: When people perceive that a diagnostic error has occurred, how does AI involvement shape patients’ and observers’ judgments of the doctor’s responsibility? Drawing on responsibility attribution theory, we examine this question across five studies—one event-rel …

02.09.2026journal-article

Acupuncture in Medicine

Tactile length-memorisation training for needle depth control: A pilot study of cross-postural skill transfer

Hirohisa Miyachi, Tsunehiko Wada, Miyono Okinaka

Objective: The aim of this pilot study was to examine whether tactile length-memorisation training practised in a single basic posture could improve insertion-depth control across different needling postures. Methods: In this single-group pre-post pilot study, eight visually impaired acupuncture students at a school for the blind performed needle insertions to a target depth of 15 mm on a prone practice model before and after a 2-week home-based tactile length-memorisation training programme. Insertions were perfor …

02.09.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

REVISÃO INTEGRADA DE TECNOLOGIAS LEVES-DURAS NA PRÁTICA MÉDICA CLÍNICA DE HIPERTENSÃO E DIABETES NA ATENÇÃO PRIMÁRIA

Laura Vitória de Melo Niesciur, Dionatan Costa Rodrigues, Bianca Camim Fernandes, Kaizza Martins Alves Aguiar, Camila Carolina Valero Guandalini, Victória Helen Caetano Ribeiro de Oliveira, Aliny Nunes da Cruz, Rosane Maria Andrade Vasconcelos

As doenças crônicas representadas pela Hipertensão Arterial Sistêmica e Diabetes Mellitus são grandes desafios para o sistema de saúde pública, mas para continuar ou pelo menos melhorar a qualidade e eficiência do atendimento prestado, são necessárias inovações inovadoras. Nesse contexto, as tecnologias leves-duras surgem como estratégias que podem qualificar a prática médica e sustentar o tratamento clínico. Investigar as implicações dessas tecnologias na prática e a inovação tecnológica no tratamento de doenças c …