Journal of Sleep Medicine
Successful Positive Health Impact of Nasal Surgery on Comorbid Difficult-to-Treat Chronic Rhinosinusitis and Severe Obstructive Sleep Apnea After Failed Medical Therapy
Obstructive sleep apnea (OSA) is a common contributor to hypertension and is strongly associated with chronic rhinosinusitis (CRS) development. OSA and CRS have a bidirectional causality. OSA causes systemic tissue hypoxia and increases liability to infection and chronic inflammation. CRS reduces nasal nitric oxide release and pulmonary vasodilation and increases pulmonary arterial pressure. Our patient had obstruction at two subsites of the upper airway: static intranasal obstruction caused by CRS with an exophyti …