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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Annals of Surgery

Real-World Analysis of Hypothermic Oxygenated Perfusion and Normothermic Machine Perfusion in Liver Transplantation

Matthias Pfister, Janina Eden, Hannah Rasel, Fariba Abbassi, Simon Störzer, Florin Botea, Bettina M. Buchholz, Francisco C. Novoa, Stefania Camagni, William C. Chapman, Umberto Cillo, Arielle Cimeno, Philippe Compagnon, Miriam Cortes-Cerisuelo, Alexander R. Cortez, Kris P. Croome, Riccardo De Carlis, Dulce Diogo, Fabrizio Di Benedetto, Daniele Dondossola, John Fung, Jiri Fronek, Carlos Garcia, Georg Györi, Matthew Hamilton, Julie K. Heimbach, Philipp Houben, Dionysios Koliogiannis, Chandrashekhar A. Kubal, Hwai-Ding Lam, Tyler Lunow-Luke, Georg Lurje, Ajay Mahenthiran, Diethard Monbaliu, Hussein Nassar, Andreas Pascher, Madhukar S. Patel, Damiano Patrono, Robert J. Porte, Lukas Prommegger

Objective: To report real-world data on hypothermic oxygenated perfusion (HOPE) and normothermic machine perfusion (NMP) in liver transplantation (LT). Summary Background Data: Real-world comparisons between HOPE and NMP are limited and methodologically challenging due to heterogeneity in donor and recipient risk profiles and regional differences in practice patterns. Methods: This international cohort study analyzed consecutive NMP-preserved LTs performed at 15 predominantly North American centers between 2021 and …

02.09.2026journal-article

Clinics in Colon and Rectal Surgery

The NICE Procedure: Surgical Technique and Technical Considerations

Diego Z. Arellano, Deborah S. Keller, Eric M. Haas

Abstract The NICE (Natural orifice IntraCorporeal anastomosis with transrectal Extraction) procedure represents an evolution in minimally invasive colorectal surgery, combining robotic precision with natural orifice specimen extraction to minimize abdominal wall trauma. The technique involves mesenteric-sparing resection of the diseased segment, transrectal natural orifice specimen extraction, and creation of an end-to-end intracorporeal anastomosis, thereby eliminating the need for an abdominal extraction-site inc …

02.09.2026journal-article

THE JOURNAL OF THE BULGARIAN ORTHOPAEDICS AND TRAUMA ASSOCIATION

Augmented Internal Fixation of Distal Femoral Fractures: Current Concepts, Biomechanical Rationale, Indications, and Clinical Evidence—A Review

Hristo Hristov, Yordan Andonov

Distal femoral fractures remain difficult to treat, particularly in older patients with poor bone quality and in highly comminuted injuries with loss of medial cortical support. Objective: To review the biomechanical rationale, indications, techniques, and reported outcomes of augmented internal fixation. Methods: A focused review of English-language clinical studies, biomechanical investigations, systematic reviews, and meta-analyses was undertaken. PubMed/MEDLINE and ScienceDirect were searched using terms relate …

02.09.2026journal-article

Frontiers in Physiology

Pulmonary sequelae of SARS-CoV-2 infection: a narrative review of long-term functional, radiological, and clinical outcomes in COVID-19 survivors, with a regional focus on Saudi Arabia

Fatimah Ali Zarbatan, Khaled Alawam, Ali Hakamy

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has left an enduring legacy of pulmonary morbidity among millions of survivors worldwide. While the acute phase of COVID-19 has been extensively characterized, the long-term pulmonary sequelae collectively termed post-acute sequelae of SARS-CoV-2 infection (PASC) or long COVID remain incompletely understood, particularly across diverse geographic and demographic populations. This narrative review synthesizes current evidence on the long-term …

02.09.2026journal-article

Journal of Rehabilitation Medicine

Identifying classes with different disability profiles amongst patients with persistent neck pain

Konsta Koivunen, Mikhail Saltychev, Juhani Juhola

Objective: To identify latent classes with distinct disability profiles among patients with persistent neck pain using item-level responses from the Neck Disability Index, and to examine demographic, clinical, and lifestyle factors associated with class membership. Design: Cross-sectional survey-based study. Patients: 962 patients with persistent neck pain. Methods: This survey-based study included 962 patients with persistent neck pain. Latent class analysis was performed using the 10 dichotomized items of the Nec …

02.09.2026journal-article

World Journal of Otorhinolaryngology - Head and Neck Surgery

The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

Diego M. Conti, Eduardo J. Correa, Alfonso Del Cuvillo, José D. Abdullatif, Francisco J. Alvarez‐Gutiérrez, Remedios Cárdenas Contreras, Stefan Cimbollek, Rocío Corrales Millán, Ana Gómez‐Bastero Fernández, Daniel Pérez‐Chada, Francisco Pérez‐Grimaldi, Alberto E. Rabino, Maria A. Romero‐Falcón, Marcela Soria, José Gregorio Soto‐Campos, Rosario B. Spuches, Juan Maza‐Solano

ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology. Methods A multidisciplinary expert panel composed of allergists, pulmonologists, and otolaryngologists from multiple tertiary care centres was convened. Experts were selected us …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Patient-Centered, Culturally Responsive Behavioral Economics Intervention to Optimize Retention in HIV Care

Vinita Sharma, Alida Gertz, Neille Saint-Cyr, Miguel Vasquez, Karen Wint, Marie-Jose Francois, Dinorah Martinez Tyson, Stephanie Marhefka, Phillip Phan, Harsha Thirumurthy, Miguel Reina Ortiz

ABSTRACT. Behavioral economics is a field that optimizes decision-making by nudging people to a desired behavior. Interventions based on behavioral economics principles have been used to improve HIV outcomes. According to the CDC, culturally responsive methods have been used to adapt other types of HIV interventions. However, culturally responsive methods have not been used to adapt HIV-focused behavioral economics interventions. This study identifies patient-centered perspectives from both patients and providers r …

02.09.2026journal-article

Journal of Racial and Ethnic Health Disparities

Psychometric Evidence for Chronic Stress Patient-Reported Outcome Measures in African American Adults: An Equity-Focused COSMIN Systematic Review

Michelle F. Robinson, Clifton Addison, Mariana Sanchez, Noel C. Barengo, Olatokunbo Osibogun, Jessy G. Devieux, Gira Ravelo, Derrick Amoah, Joe F. Coleman, Gequasha Collins, Elena Bastida

Abstract Introduction Chronic stress is a well-documented psychosocial driver of cardiovascular disease (CVD) disparities disproportionately affecting African American adults, yet the psychometric adequacy of patient-reported outcome measures (PROMs) in this population remains unexamined. This systematic review evaluated the scientific evidence on the psychometric quality of chronic stress PROMs in a racially specific population at elevated cardiovascular risk. Methods PubMed/MEDLINE, Embase, CINAHL, and PsycINFO w …

02.09.2026journal-article

Biomolecules

Post-Exposure JNJ-26366821 Treatment Attenuates Systemic Inflammation and Limits Cardiotoxic Risk

Nabarun Chakraborty, Gregory P. Holmes-Hampton, Lily S. Neff, Vidya P. Kumar, Swapna Kannan, Amrita Cheema, Chandan Guha, Sanchita P. Ghosh, Rasha Hammamieh

Introduction: Thrombopoietin mimetics (TPOm) are known to increase blood cell counts, thereby ameliorating various diseases, including cardiomyopathy—a leading cause of mortality because of delayed radiotoxic effects. Previous preclinical studies demonstrated significant survival enhancement following lethal radiation exposure with a single dose of JNJ-26366821 in two mouse strains, CD2F1 and C57BL/6. Materials and Methods: In this study, a single dose of JNJ-26366821 (1.0 mg/kg) or saline was administered 24 h pos …

02.09.2026journal-article

Clinical Spine Surgery

Effects of Adding a Cross-Link During Single-Level Lumbar Interbody Fusion for Degenerative Lumbar Spine Diseases: A Computed Tomography-Based Analysis

Koichiro Shima, Bungo Otsuki, Koichi Murata, Takayoshi Shimizu, Takashi Sono, Shintaro Honda, Masaki Sakamoto, Takaki Yoshiyama, Ryohei Saito, Shuichi Matsuda

Study Design: Retrospective study. Objectives: To evaluate whether adding cross-links during single-level lumbar interbody fusion (LIF) improves fusion rates, segmental alignment, and clinical outcomes. Summary of Background Data: Biomechanical studies suggest cross-links enhance rotational stability in single-level posterior lumbar interbody fusion, but clinical evidence for their benefit in degenerative lumbar spine diseases remains limited. No previous clinical study has investigated how cross-link addition affe …

02.09.2026journal-article

Journal of Traditional Medicine & Applications

Medication Adherence and Associated Factors Among Hypertensive Outpatients in Sana’a City, Yemen: A Cross-Sectional Study

Al-Maswari S N, Adnan Ali Alradhi, Taha Ali Al Sorouri, Ahmed Hamood Al-Shahethi

Background: Hypertension is the second most prevalent chronic disease in Yemen and a leading contributor to cardiovascular complications. Poor blood pressure control is often linked to low medication adherence, which remains underexplored in the country. Objective: This study aimed to assess the level of adherence to prescribed antihypertensive medications and identify demographic, socioeconomic, knowledge, and awareness-related factors associated with adherence among hypertensive outpatients in Sana’a City, Yemen. …

02.09.2026journal-article

Montenegrin Journal of Sports Science and Medicine

Greater Goal Difference is Associated with Lower Physical Demands in Cerebral Palsy Football Referees

Eñaut Ozaeta-Beaskoetxea, Daniel Castillo, Raul Reina, Matías Henríquez, Ibai Errekagorri, Javier Yanci

This study examines the association between match outcome variables, total goals, goal difference, and the physical demands placed on referees in cerebral palsy (CP) football. Thirteen international referees were monitored via global positioning devices during 42 official matches at the 2022 CP Football World Cup and World Championships. Physical demands, including distances covered at various speeds and acceleration/deceleration metrics, were analyzed. Results revealed moderate to high negative correlations betwee …

02.09.2026journal-article

Annals of Surgery

Multidisciplinary Rehabilitation Following Upper Gastrointestinal Cancer Surgery (RESTORE II)

Linda M. O’Neill, Emily Smyth, Neil Kearney, Grainne Sheill, Louise Brennan, Sophie Grehan, Sanela Begic, Fiona Murphy, Ciara Tansey, Niamh Flanagan, Mikel Egaña, Ricardo Segurado, Marie Galligan, Jinbo Zhao, Ciaran M. Fairman, Claire M. Timon, Suzanne L. Doyle, Deirdre Connolly, Jacintha O’Sullivan, John V. Reynolds, Juliette Hussey, Emer M. Guinan

Objective: RESTORE II compared in an RCT the impact of a 12-week multidisciplinary rehabilitation program versus standard care (SC) on cardiorespiratory fitness and physical function in patients postupper gastrointestinal (UGI) oncologic surgery. Summary of Background Data: The value of multidisciplinary cancer rehabilitation in UGI cancer survivorship is unclear, with limited high-quality data. Methods: Disease-free patients, ≥3 months post-UGI cancer resection were randomized to SC or RESTORE (physiotherapy-led a …

02.09.2026journal-article

Anaesthesia

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery ( POPPY ): acute pain and recovery during the first 7 days

Matthew Everson, Martha Belete, Adam Brayne, Harriet Daykin, William M. Hare, Anna Ratcliffe, Lexy Sorrell, the POPPY study delivery group, Mark Rockett, the Research and Audit Federation of Anaesthetists in Training

Summary Introduction The majority of surgical cases in the UK occur in a day‐case setting. Published short‐term follow‐up studies after day‐case surgery are lacking and patterns of recovery including pain and patient reported outcome measures, are largely unknown. Methods Data from the Patient‐reported Outcomes, Postoperative Pain and pain relief after daY case surgery (POPPY) study, a national, prospective, observational study exploring outcomes following day‐case surgery in the UK, were used to explore acute reco …

02.09.2026journal-article

Indian Journal of Community Medicine

Monitoring Field-Level Compliance and Temporal Trends of Statutory Pictorial Health Warnings on Tobacco Products in India, 2020–21: A 21-City Observational Study

Shivam Kapoor, Puneet Chahar, Garima Bhatt, Jyoti Choudhary, Aastha Bagga, Surjeet Singh, Rana J. Singh, Amit Yadav

Abstract Objective: To strengthen the WHO-Framework Convention on Tobacco Control (FCTC) MPOWER “warn” component, India implemented 85% pictorial health warnings (PHWs) on all tobacco packs in 2016, allowing a two-month grace period to clear old stock. We monitored compliance and the time taken to comply with the revised PHW rules effective December 1, 2020, during December 2020–May 2021. Methods: A cross-sectional survey assessed one prominent tobacco point-of-sale (PoS) in each of 21 cities across nine Indian sta …

02.09.2026journal-article

Emergency Medicine Australasia

Ultrasound Archiving in the Emergency Department: Implementation, Governance and 4‐Year Outcomes at an Australian Tertiary Emergency Department

Vijay Manivel, Behzad Mirmiran, Claire Helm, Cindy Hastings

ABSTRACT Objective Image archiving is one of the least developed aspects of emergency department ultrasound (ED‐US) in Australasia, despite its recognised role in governance, education, quality assurance (QA) and medicolegal protection. A middleware‐based ED‐US image workflow solution was installed at Nepean Hospital ED in October 2021. We describe our implementation and 4‐year experience with a dedicated ED‐US archiving solution at a tertiary Australian ED. Methods Single‐centre retrospective analysis of service i …

02.09.2026journal-article

Healthcare

Turkish Cross-Cultural Adaptation of the BRIEF-MPI in Older Adults with Cancer: Convergent and Discriminative Validity Compared with the G8 and Clinical Frailty Scale

Sercan On, Haydar Cagatay Yuksel, Semih Sergen Semerci, Ecem Ozdemir, Mustafa Kagan Ozdel, Fatma Ozge Kayhan Kocak

Background: Older adults with cancer represent a heterogeneous population with varying levels of frailty and multidimensional vulnerability. Rapid screening tools are needed to identify patients who may benefit from comprehensive geriatric assessment (CGA). This study aimed to translate and culturally adapt the Brief Multidimensional Prognostic Index (BRIEF-MPI) into Turkish and evaluate its performance in older adults with cancer. Methods: This cross-sectional methodological study included 177 patients aged ≥65 ye …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Malaria Incidence, Growth, and their Relationship among a Cohort of Malawian Children

Divya Hosangadi, Liana R. Andronescu, Patricia Mawindo, Don P. Mathanga, Terrie Taylor, Miriam K. Laufer, Andrea G. Buchwald

ABSTRACT. Child growth impairment and Plasmodium falciparum ( P. falciparum ) infection pose substantive public health challenges, particularly in sub-Saharan Africa. There is a paucity of evidence regarding how P. falciparum infection, which causes clinical malaria, relates to child growth in children under 24 months old. To assess the temporal associations between P. falciparum infection and weight-for-age Z score (WAZ), a secondary analysis of a prospective cohort study conducted from 2016 to 2018 in which 86 Ma …

02.09.2026journal-article

Frontiers in Medicine

Toward nursing-integrated biomarker surveillance for immune-related adverse events during immune checkpoint inhibitor therapy

Jiafeng Jin, Liwen Zheng, Yali Tian, Minjuan Chu, Beinuo Cao

Immune checkpoint inhibitors (ICIs) have transformed cancer care but can cause immune-related adverse events (irAEs) involving almost any organ system. Delayed recognition may permit reversible inflammation to progress to organ dysfunction, treatment interruption, prolonged immunosuppression, or death. Biomarker surveillance offers an objective complement to symptom assessment, yet no single marker is sufficiently accurate for universal prediction. This Mini Review examines the mechanistic basis and clinical eviden …

02.09.2026journal-article

Physics in Medicine & Biology

Assessment of elemental decomposition algorithms for particle therapy dose monitoring using positron emission tomography and prompt-gamma imaging

Yan Li, Weiguang Li, Xinyu Hu, Yuying Yin, Xueying Yang, Shutong Yu, Chao Yang, Cheng Chang, Mingqing Wang, Kai-Wen Li, Lisheng Geng, Yibao Zhang

Abstract Objective: Accurate dose verification remains a major challenge in particle therapy. Dose monitoring methods such as positron emission tomography (PET) and prompt-gamma (PG) imaging are highly sensitive to uncertainties in tissue composition derived from CT, which can be improved by dual-energy CT (DECT)-based material decomposition. This study systematically assessed the accuracy of four DECT elemental decomposition algorithms in predicting physical dose, annihilation-photon, and PG reference distribution …

02.09.2026journal-article

Physics in Medicine & Biology

Hamiltonian dynamics for stochastic reconstruction in emission tomography

Theodoros Leontiou, Anna Frixou, Elena Ttofi, Charalambos Chrysostomou, Yiannis Parpottas, Konstantinos Michael, Savvas Frangos, Efstathios Stiliaris, Costas N Papanicolas

Abstract Objective. To develop a practical stochastic reconstruction framework for emission
tomography that generates ensembles of data-compatible images and enables
uncertainty quantification and assessment of forward-model adequacy. Approach. 
The framework combines stochastic-gradient descent initialization with
Hamiltonian Monte Carlo (HMC) sampling directly in high-dimensional voxel
space. Beyond point reconstruction, we introduce a spatially resolved
operator-weighted diagnostic, the s …

02.09.2026journal-article

Medicine Insights

Analyzing the Intrinsic Links and Common Therapeutic Targets between Diabetic Foot Ulcers and Liver Disease through Bioinformatics

Wenbo Li, Xudong Xin, Tianyi Shen, Zhenhao Zhang, Jihua Wei

Background. Diabetic foot ulcer (DFU) is a critical and prolonged complication of diabetes associated with high disability and mortality rates. Lipid metabolism disorders resulting from liver diseases are a key etiology in the development of diabetes mellitus and diabetic foot. Currently, there are no effective therapeutic targets or medications for treating DFU in combination with liver diseases such as nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) and liver cirrhosis (LC). The intri …

02.09.2026journal-article

Journal of Clinical Psychopharmacology

The Randomization Effect in a Double-Blind Placebo-Controlled Depression Study

Steven D. Targum, Paulette Ceesay, Christopher Lines, Michael E. Thase, Gerard Sanacora, Aristide Merola

Background: Double-blind, placebo-controlled trials are often affected by higher-than-anticipated placebo responses that may contribute to study failure. It is common to observe symptomatic improvement immediately after randomization regardless of treatment allocation. Methods: This post hoc analysis examined the early randomization effect in a recent 4-week double-blind, placebo-controlled study that examined a novel presynaptic mGluR2 inhibitor, MK-1942, in a daily or twice-weekly dosing strategy versus placebo a …

02.09.2026journal-article

Journal of Clinical Medicine

International Imaging Practices for Sacroiliac Joint MRI Acquisition Protocols in Patients with Juvenile Spondylarthritis

Arthur B. Meyers, Mirkamal Tolend, Walter P. Maksymowych, Rawan Hafiz, Tarimobo M. Otobo, Jacob L. Jaremko, Robert G. W. Lambert, Nele Herregods, Marion A. J. van Rossum, Jennifer Stimec, Simone Appenzeller, Shirley Tse, Philip G. Conaghan, Lennart Jans, John A. Carrino, Eva Kirkhus, Joke Dehoorne, Pamela F. Weiss, Andrea S. Doria

Background/Objective: International recommendations exist for MRI evaluation of sacroiliac joints (SIJs) in adult spondylarthritis (SpA) and other joints in juvenile (J)SpA. However, consensus recommendations for MRI acquisition protocols for SIJs in JSpA are lacking. Our survey gathered information on current imaging practices on SIJ MRI and expert opinions about imaging protocols. Methods: A survey was sent to an international group of pediatric radiologists and rheumatologists. Participants were asked about prac …