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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
13.08.2026journal-article

SLEEP Advances

The Association of Sleep Health with Epigenetic Aging in Early Adolescence: Exploratory Insights from the HOME Study

Smriti Maskey, Jennifer Arzu, Aimin Chen, Karl T Kelsey, Scott M Langevin, Kim M Cecil, Kimberly Yolton, Joseph M Braun, Clara G Sears

Abstract Study Objectives Sleep during adolescence may influence biological aging, yet few studies have examined this association using objective sleep measures. We examined the associations between accelerometry-based sleep characteristics and epigenetic age (EA), epigenetic age acceleration (EAA), and the pace of biological aging. Methods For this preliminary analysis, we used data from the HOME Study (Cincinnati, OH). At age 12 years (2016-2019), we used accelerometers to assess total sleep time, sleep efficienc …

13.08.2026journal-article

Cellular and Molecular Life Sciences

Comparative analysis of neuronal proteolytic pathways reveals neuron-specific and sub-compartmental-specific capacities with aging

Mira Sleiman, Dimitra Ranti, Sudarson Baskaran, Patricia Kreis, Saskia Muth, Christian Gallrein, Agnieszka Münster-Wandowski, Norman Rahnis, Emilio Cirri, Britta J. Eickholt, Janine Kirstein

Abstract Proteostasis is essential for maintaining neuronal function, and its dysregulation is a hallmark of aging and neurodegeneration. The ubiquitin–proteasome system (UPS) and macroautophagy are the two major proteolytic pathways responsible for protein degradation. However, their capacity and regulation differ between cell types and across aging. To elucidate the activity of both proteolytic pathways with aging, we performed a comparative analysis of the activity of UPS and macroautophagy in distinct neuronal …

13.08.2026journal-article

Working with Older People

Working with complexity in later life: co-occurrence of physical, mental/emotional and social needs across SHARE countries

Javier García García

Purpose This study aims to examine the co-occurrence of physical, mental/emotional and social needs among people aged 65 and over across SHARE countries. Design/methodology/approach Cross-sectional data from SHARE Wave 9 were analysed for 41,437 respondents with complete information on three standardised need indices. Pearson correlations assessed associations between dimensions. Upper-quartile scores identified high need in each domain, enabling calculation of accumulated need and cross-country comparisons. Chi-sq …

13.08.2026journal-article

Frontiers in Public Health

Cognitive impairment and associated factors among community-dwelling older adults with hypertension in tropical China

Liyu Peng, Xiuru Wang, Wenting Cao, Ping Zhang, Dee Yu, Huajiang Liu, Yong You, Binwen Huang, Jindong Ding Petersen

Background Cognitive impairment (CI) is highly prevalent among older adults with hypertension and imposes substantial burdens on individuals, families, and healthcare systems. Identifying factors associated with CI is essential for developing targeted prevention strategies, yet evidence from tropical regions of China remains limited. Objective To examine the prevalence of CI and factors associated with CI among community-dwelling older adults with hypertension in tropical China. Methods This community-based cross-s …

13.08.2026journal-article

Desenvolvimento e Meio Ambiente

Bioculturalidade do povo Tembé: um estudo de caso sobre estratégias de r-existência na Terra Indígena Alto Rio Guamá (TIARG), no Pará, Brasil

Carlos do Socorro Guerreiro Vaz, Márlia Regina Coelho-Ferreira, Flávia Cristina Araújo Lucas

Este artigo analisa a bioculturalidade como estratégia de resistência dos indígenas Tembé-Tenetehar, diante das ameaças ambientais e territoriais que incidem sobre a Terra Indígena Alto Rio Guamá (TIARG), no Pará. A bioculturalidade, entendida como a interdependência entre biodiversidade, cultura e diversidade linguística, é essencial para a compreensão da relação dos povos indígenas com seus territórios e para a manutenção da identidade e sobrevivência dos povos indígenas. A pesquisa, de abordagem qualitativa, bas …

13.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

Culturally Meaningful Leisure Among Caribbean Diaspora Older Adults in the United States: A Qualitative Study

Nardia Aldridge, Mikayla Dunn, Reagan Smith, Jada Wood, Brittnie Milhomme

Leisure participation supports well-being and positive aging; however, limited research has examined culturally meaningful leisure among Caribbean older adults living in diaspora communities. This qualitative phenomenological study explored the lived experiences of culturally relevant leisure and its relationship to well-being and quality of life among community-dwelling Caribbean older adults in the United States. Ten participants completed in-depth semi-structured interviews examining leisure participation, cultu …

13.08.2026journal-article

Journal of Applied Gerontology

Age Identities and Health Among Older Adults: Empirical Evidence From China

Yawen Fan, Wenwen Liu, Xiaohui Zhang, Chenyu Yan

This study uses data from the 2018 and 2020 waves of the China Longitudinal Aging Social Survey (CLASS) to examine the association between age identities and health among older Chinese adults. Findings show that a relatively younger age identity is significantly linked to better self-rated health. Mechanism analysis identifies three behavioral pathways: increased voluntary labor participation, greater digital inclusion, and more active social connections. These attitudes act as psychological assets that encourage p …

13.08.2026journal-article

Family Relations

Latent Patterns of Older Parents' Perceived Intergenerational Relationships in Urban China: The Role of Coresidence

Bin Lian, Ning Wang

ABSTRACT Objective This study examines latent patterns of older parents' perceived intergenerational relationships (PIR) in urban China and their associations with living arrangements, particularly the gender and marital status of coresiding adult children. Background Intergenerational relationships are often studied through support exchanges, but older parents' subjective perceptions of relationships remain less understood, especially in non‐Western contexts. Method Using data from the 2021 Shanghai Family Cohort …

13.08.2026journal-article

Annals of Clinical and Translational Neurology

Anti‐ CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat

ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy. Methods This observational, multicenter, retrospective cohort study included 2283 patients from the French MS registry aged > 50, who had received at least two cycles of anti‐CD20 and had experienced no relapses or MRI activity for at least on …

13.08.2026journal-article

Journal of Sleep Research

The Effects of Nasal and Multi‐Level Upper Airway Surgery on Upper Airway Collapsibility and Non‐Anatomical Endotypes in People With Obstructive Sleep Apnoea—A Pilot Study

Amal M. Osman, A. Simon Carney, Himani Joshi, Phuc Nguyen, Peter Catcheside, Eng H. Ooi, Danny J. Eckert

ABSTRACT Nasal breathing is the preferred route of breathing during sleep. Indeed, nasal blockage can cause obstructive sleep apnoea (OSA) in otherwise healthy people. Whilst multi‐level pharyngeal surgery reduces OSA severity, efficacy varies and changes in OSA pathophysiology post‐surgery have not been well characterised. Similarly, whether isolated nasal surgery improves upper airway collapsibility and OSA severity remains unclear. Accordingly, this study aimed to assess changes in upper airway collapsibility an …

13.08.2026journal-article

Journal of Organizational Effectiveness: People and Performance

What AI builds for organisations: an organisational capital perspective on the AI–HRM literature

Karuna Seth, Ashish Kant Chaudhari

Purpose The literature around artificial intelligence (AI) and human resource management (HRM) has grown rapidly since 2019, yet it has theorised AI as a phenomenon acting on individuals rather than as a process that builds organisational structures. This matters because organisations making substantial investments in AI-driven HR systems currently lack any theoretical framework for evaluating whether those investments are accumulating as durable structural assets or dissipating as operational expenditure. This art …

13.08.2026journal-article

Working with Older People

Ageing of former manual scavengers in India: occupational health vulnerability, social exclusion and healthy ageing

Aniket Godse, Saikat Deb, Vinod Sharma

Purpose This paper aims to build a conceptual framework to examine the consequences of biological and occupational ageing among former manual scavengers in India. It determines the effects of ageing on social inclusion, perceived dignity, economic security and healthy ageing through considering the mediation of occupational health vulnerability and the moderation of safeguarding mechanisms. Design/methodology/approach This paper summarizes the interdisciplinary literature to hypothesize the conceptual framework tha …

13.08.2026journal-article

PLANTS, PEOPLE, PLANET

Beyond forests: Harnessing conservation gardening for open biomes in Brazil

Flávia Santos Faria, Luciane Vilela Resende, Fernando A. O. Silveira

Societal Impact Statement Urban gardening offers an innovative conservation strategy by integrating native ornamental species into urban landscapes. We evaluated the ornamental potential of the Brazilian flora by comparing the representation of species from forests versus open biomes (focusing on campo rupestre grasslands) and introduced and validated the Index of Ornamental Potential (IOP). Despite high IOP values, species from open biomes were underrepresented in the ornamental market, indicating an untapped reso …

12.08.2026journal-article

Journal of the American Geriatrics Society

Barriers to Research Participation Among Older Rural Veterans: Early Insights to Strengthen Frameworks for Age‐Inclusive Research

Justine Seidenfeld, Emily Franzosa, Megan Shepherd‐Banigan, C. Barrett Bowling, Nathan A. Boucher

ABSTRACT Background Older, rural adults face compounded barriers to participating in research, and existing frameworks that guide study design to improve the recruitment and retention of older adults, such as the 5Ts Framework, require adaptation to address them. Older, rural Veterans are one such underrepresented population. Drawing on the expertise of multiple research stakeholders within the VA Health Care System, this effort aimed to develop preliminary insights for refining the framework to better address the …

12.08.2026journal-article

GeroScience

Lifestyle correlates of verbal memory in community-dwelling older adults

Zihan Ding, Agnes S. Chan

Abstract Verbal memory decline is an early marker of dementia. This study aims to identify significant lifestyle correlates of verbal learning and memory among older adults to inform intervention targets for maintaining cognitive health in late life. The sample included 221 community-dwelling Chinese older adults (60–80 years). Verbal learning and memory were assessed using the Hong Kong List Learning Test (HKLLT). Lifestyle factors, emotion, demographics, and medical history were assessed using questionnaires. Bod …

12.08.2026journal-article

Frontiers in Aging Neuroscience

Non-invasive brain stimulation on functional capacity in prefrail older adults: a protocol for a randomised clinical trial

Pilar Serra-Añó, Elena Muñoz-Gómez, Sara Mollà-Casanova, Noemí Moreno-Segura, Héctor González-Pons, Marta Inglés

Introduction Therapeutic physical exercise (TPE) is considered the cornerstone intervention to prevent or reverse frailty; however, prefrail individuals often face challenges achieving the exercise intensity required to induce multisystem adaptations. Non-invasive neuromodulation techniques—including virtual running–based visual illusion (VR) and, transcranial direct current stimulation (tDCS),—have shown promising effects on neuroplasticity, motor performance and executive function. The primary objective of this s …

12.08.2026journal-article

European Geriatric Medicine

Effect of bodyweight interval training on frailty status in older adults: a randomized controlled trial

Lucas Marques Vieira, Danilo Sales Bocalini, Clarcson Plácido Conceição dos Santos, Leandro Brasil Rego, Rodrigo Villar, Aylton José Figueira Júnior, Rodrigo Chaves da Silva, Ana Paula de Souza Lima, Ruy Barbosa Martins Calheiros Netto, Felício Savioli Neto, Taina Costa Nonato, João Paulo Pinto, Francisco Luciano Pontes Júnior

Abstract Purpose To evaluate the effect of bodyweight interval training on frailty status in older adults. Methods A randomized controlled trial was conducted with 60 frail older adults (74.0 ± 6.0 years; 72.4% women). Participants were allocated to bodyweight interval training (BWIT = 30) for 24 weeks or to a control group (CG = 30) instructed to maintain their usual physical activities. Frailty status (Fried phenotype), physical-functional performance, cardiohemodynamic responses, and body composition were assess …

12.08.2026journal-article

Journal of Cardiovascular Nursing

A Nurse-Led Metamemory-Based Intervention to Improve Medication Adherence in Older Adults With H-Type Hypertension: A Randomized Controlled Trial

Gang Wu, Sixuan Li, Qiansheng Jin, Jiang Nan, Xuehua Liu, Lingxiang Guo

Background: H-type hypertension substantially increases cardiovascular and cerebrovascular risk in older adults, yet long-term medication adherence remains suboptimal. Beyond regimen complexity, age-related cognitive vulnerability and limited self-monitoring capacity may undermine adherence. However, few nurse-led interventions explicitly target memory-related mechanisms underlying medication-taking behavior. Objective: To evaluate the effectiveness of a nurse-led, metamemory-based intervention in improving medicat …

12.08.2026journal-article

Journal of the American Geriatrics Society

Exposure to Ageism Among United States Older Adults With and Without Chronic Pain: Prevalence and Associations With Pain‐Related Treatment Factors

Emily C. Harris, Lisa R. LaRowe, Gab Pasia, Meera Srinivasan, Andrea Mayfield, John Dombrowski, Francis J. Keefe, Alexander K. Smith, Bruce A. Cooper, Lee‐Jen Wei, Christine Miaskowski, Christine S. Ritchie

ABSTRACT Background Recent work suggests age discrimination can increase the risk for chronic pain among older adults. This study's aim was to examine the prevalence of exposure to ageism and its impact on chronic pain. Methods A nationally representative sample of 2029 adults ≥ 65 years old was recruited from the AmeriSpeak Panel. Participants were asked about five experiences of ageism. Older adults with chronic pain (pain on most/nearly every day in the past 3 months) reported pain self‐efficacy, barriers to tre …

12.08.2026journal-article

Frontiers in Aging Neuroscience

Cortical and subcortical morphological alterations in de novo GBA-related Parkinson’s disease

Jingru Ren, Yi Xing, Hao Zhou, Xinyu Hong, Xiaofang Huang, Weiguo Liu

Background This study aimed to investigate cortical and subcortical changes in GBA -related Parkinson’s disease ( GBA -PD) patients and evaluate the ability of these structural changes to identify patients with GBA -PD. Methods T1-weighted magnetic resonance imaging images were obtained for 86 participants, including 19 GBA -PD, 42 idiopathic PD (iPD) cases, and 25 healthy controls (HCs). Cortical thickness, cortical volume, and subcortical volume (including amygdala volume) were calculated to identify cortical and …

12.08.2026journal-article

Frontiers in Child and Adolescent Psychiatry

The role of receptive arts and culture to improve anxiety, depression and psychological distress in young people: a realist review

Daniel Hayes, Joely Wright, Louise Chandler, Kayleigh Albaya de Gago, Summi Ng, Joe Langley, Daisy Fancourt, Kamaldeep Bhui, Roisin Mooney, Rebecca Syed Sheriff

Background Arts and culture are increasingly recognised as potential supports for mental health, yet little distinction has been made between receptive engagement (e.g., visiting museums, watching performances, listening to music) and active participation (e.g., creating art or attending classes). There is limited understanding of how, for whom, and under what circumstances receptive engagement may influence anxiety, depression, and psychological distress in young people. Method We conducted a realist review of evi …

12.08.2026journal-article

Caderno de Educação Física e Esporte

Impactos da BNCC sobre a inclusão de pessoas com deficiência nas aulas de Educação Física: uma revisão do estado do conhecimentolas de Educação Física

Adriana Edwirgen Maia de Castro, Felipe da Silva Triani

OBJECTIVE: To discuss the impacts of the National Common Curricular Base on Physical Education in schools, from an inclusive perspective. METHODS: This study mapped scientific literature on the possible impacts of the BNCC on the inclusion of people with disabilities in Physical Education classes. A qualitative approach was used to produce the data, based on a State of Knowledge study. The research for the texts that comprised the review was conducted in Google Scholar, SCIELO Brazil, and the Theses and Dissertatio …

12.08.2026journal-article

Frontiers in Public Health

Factors associated with unmet medical needs among people with disabilities using Andersen's model in South Korea

Ye-Soon Kim, Mi Jin Kim, Seon-Deok Eun

Objective This study applied Andersen's behavioral model to identify unmet medical needs and related associated factors among people with disabilities. Methods The analysis was conducted on 7,581 people with disabilities aged ≥20 years, obtained from the 2023 Survey on People with Disabilities in Korea. Results The results showed that 17.2% of people with disabilities reported wanting to visit a medical institution but were unable to do so. The main reasons for unmet medical needs were “difficulty in transportation …

12.08.2026journal-article

Frontiers in Dementia

Premature and early menopause and neuroimaging biomarkers of neurodegenerative diseases: a systematic review

Emily Gallmetzer, Elijah Mak, Firat Kara, Burcu Zeydan, Ekta Kapoor, Chrisandra L. Shufelt, Walter A. Rocca, Kejal Kantarci

Background Premature and early menopause involve ovarian hormone deprivation, which may contribute to later-life vulnerability to cognitive decline and neurodegenerative diseases. Multimodal neuroimaging biomarkers provide a means of detecting structural, microstructural, functional, and molecular brain changes before clinical symptoms emerge. Methods Following PRISMA guidelines, we conducted a systematic search of PubMed. Study quality was assessed using the Newcastle–Ottawa Scale. Results Neuroimaging modalities …