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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

Cancer Diagnosis & Prognosis

Malignant Myoepithelioma Arising from the Upper Arm With Brachial Plexus Involvement: A Rare Case

HAYATO TATSUMI, TOSHIHIRO MATSUO, TAKASHI NISHISAKA, YUI HATTORI, KOJI NISHIDA, RYOUSUKE MATSUSHITA, MASAHIRO YOSHIKAWA, SATOSHI AKI, NOBUO ADACHI

Background/Aim: Malignant myoepitheliomas (MMs) are infrequent, and the site of upper arm is extremely rare. To our knowledge, only two cases occurred in the upper arms according to previous reports. Case Report: A 73-year-old male presented with a growing mass in his left upper arm one year prior to surgery. After a needle biopsy, histopathological analysis revealed the mass to be a myxoid sarcoma but did not reach to definite diagnosis. The tumor was excised from the brachial plexus. The brachial artery and vein …

03.09.2026journal-article

Considerations in Medicine

Self-medication practices in the Santhal community: insights into knowledge, practices and attitudes

Sree Sudha T Y, Krishna Sasanka K S B S, Sumit Kumar Mahato, Kusum Kumari, Mamta Shukla, Kazi Afreen Jahan, Harminder Singh

Background To assess the prevalence, knowledge, practices and attitudes related to self-medication among the Santhal tribal community of Santhal Pargana, Jharkhand, India. Methods A community-based cross-sectional study was conducted with 102 participants from June to December 2024 among adults aged ≥20 years residing in villages served by primary health centres in Santhal Pargana. Participants who reported self-medication during the preceding 3 months were recruited using convenience sampling. Data were collected …

01.09.2026journal-article

Journal of the European Society of Surgery

Immediate Postoperative Recurrence of a Large Hiatus Hernia After Laparoscopic Nissen Fundoplication Without Suture Disruption: A Case Report

Manish Madnani, Kamran Khan, Shashi Tiwari, Suhail Kazim

Background: Recurrence of a repaired hiatus hernia after antireflux surgery is a well-recognised late complication, but recurrence within the first 24 hours, without disruption of the crural or wrap sutures, is exceptionally rare. Case Presentation: A 28-year-old man underwent laparoscopic Nissen fundoplication with hiatal repair for a large hiatus hernia with severe gastroesophageal reflux disease. Three crural sutures (Ethibond 2-0) were placed and a 360-degree wrap fashioned over a 40 French bougie, with the wra …

03.09.2026journal-article

Journal of Applied Clinical Medical Physics

Evaluation of inter‐fractional anatomical variations due to compression belt placement reproducibility using MR‐guided radiotherapy treatment fraction images

Olivia Shay, David Solis, Morgan Aire, Christopher Schneider, Krystal Kirby

Abstract Background Abdominal compression (AC) using a belt‐based system is widely employed in radiation therapy to limit respiration‐induced target motion for abdominal and hepatic malignancies. While AC has demonstrated efficacy in reducing intrafraction motion amplitude, the interfractional anatomical consequences of daily compression belt (CB) placement variability remain poorly characterized. A clearer understanding of this variability is necessary to determine whether online adaptive radiotherapy (oART) is re …

01.09.2026journal-article

Annals of Clinical and Analytical Medicine

Evaluation of the relationship between lifestyle factors and vitamin D levels in healthcare workers

Fatma Zehra Ağan, Çiğdem Cindoğlu, Velat Aytekin, Veysel Ağan

Aim This study evaluated the effects of lifestyle habits on serum 25(OH)D levels and the prevalence of vitamin D deficiency among healthcare workers. Methods In this retrospective study, laboratory and demographic data of 204 healthcare workers who attended the Internal Medicine outpatient clinic between January 1, 2023, and January 1, 2024, and had serum vitamin D levels measured were analyzed. Lifestyle factors, including sun exposure, clothing style, physical activity, smoking, and alcohol use, were assessed usi …

01.09.2026journal-article

The Annals of The Royal College of Surgeons of England

CORESS Feedback: Cases from the Confidential Reporting System for Surgery

HJ Corbett, W Hawkins

CORESS is an independent charity. Past CORESS cases can now be identified using a searchable CORESS case database, available via our website ( coress.org.uk ). We are grateful to those who have provided the material for these vignettes, some of which come from NHS England and Getting It Right First Time reports. The online reporting form is available on the CORESS website, which also includes previous Feedback reports. Published cases are acknowledged by a Certificate of Contribution, which may be included in the c …

01.09.2026journal-article

Journal of Dance Medicine & Science

The Rainbow Rift: LGBTQ+ Inclusivity and Wellbeing in the Ballet World

Rhiannon J. Watkin-Fairless, Ilana Seager van Dyk

Introduction: While the performing arts are often considered a safe space for LGBTQ+ individuals, classical ballet reflects gender disparities, with gay men highly visible and others comparatively underrecognised. Empirical research on LGBTQ+ ballet dancers remains limited. This study explored sexual orientation and gender identity (SOGI) demographics in an international sample of professional ballet dancers and examined differences in wellbeing by LGBTQ+ status using measures of workplace authenticity and wellbein …

04.09.2026journal-article

Orthopaedic Journal of Sports Medicine

Artificial Intelligence–Based Prediction of Prognosis After Nonsurgical Treatment for Medial Meniscus Posterior Root Tear

Hong Yeol Yang, Inhwan Bae, Ji Won Kim, Gyunghwan Bae, Youzhen Zheng, Sung Ju Kang, Jong Keun Seon

Background: Medial meniscus posterior root tear (MMPRT) is recognized as one of the leading causes of knee osteoarthritis. Given the detrimental effects of MMPRT on knee kinematics and the associated clinical consequences, substantial efforts have been directed toward improving the understanding and management of MMPRT. Purpose: To develop and validate an artificial intelligence (AI)–based prediction model for patient-specific risk assessment of clinical failure at 2 and 5 years after nonsurgical treatment of MMPRT …

04.09.2026journal-article

Therapeutic Advances in Hematology

A real-world, multi-center, prospective, observational study for paroxysmal nocturnal haemoglobinuria (PNH) in China: Baseline characteristics, disease burden and treatment patterns

Bing Han, Hui Liu, Guangsheng He, Jinsong Jia, Mei Hong, Jianyu Weng, Shunqing Wang, Fengkui Zhang, Ting Niu, Tianjun Ma, Jinghan Xu, Rong Fu

Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare life-threatening hematologic disorder with high thromboembolic mortality. In the context of large patient population and limited use of complement inhibitors, the clinical characteristics and disease progression of patients in China have not been well studied. Objectives The China PNH Registry was initiated to advance understanding of the disease by collecting data and describing PNH disease burden, progression, and clinical outcomes with different medi …

06.09.2026journal-article

Scandinavian Journal of Medicine & Science in Sports

Microstructural Brain Reserve Moderates the Associations Between 24‐h Movement Behaviors and Cognition in Older Adults: Cross‐Sectional Findings From the AGUEDA Trial

Beatriz Fernandez‐Gamez, Patricio Solis‐Urra, Javier Sanchez‐Martinez, Alessandro Sclafani, Marcos Olvera‐Rojas, María Teresa Rodríguez‐Palacios, Maddison L. Mellow, Dorothea Dumuid, Ashleigh E. Smith, Francisco B. Ortega, Irene Esteban‐Cornejo

ABSTRACT This study examined the associations between 24‐h movement behaviors and cognitive function in cognitively unimpaired older adults, and whether Alzheimer's disease brain signatures, including gray matter mean diffusivity (GMMD) and thickness/volume signatures, moderated these associations. A total of 91 participants were enrolled in the AGUEDA trial (NCT05186090), with 89 included in this cross‐sectional analysis (mean age = 71.61 ± 3.85 years; 56.2% females). Moderate‐to‐vigorous physical activity (MVPA), …

02.09.2026journal-article

Clinical Cardiology

Longitudinal Serum Uric Acid Variation and Risk of Major Adverse Cardiovascular Events and Mortality: A Systematic Review and Meta‐Analysis

Saima Nisar, Asif Shah, Abida Perveen

ABSTRACT Background Longitudinal variability in serum uric acid (SUA) has emerged as a potential predictor of adverse cardiovascular outcomes beyond a single baseline measurement. However, the relationship between temporal changes in SUA and major adverse cardiovascular events (MACE) and mortality remains unclear. This systematic review and meta‐analysis evaluated the association between longitudinal variation in SUA and cardiovascular events and mortality. Methods A systematic search of PubMed/MEDLINE, Embase, Sco …

01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Evaluation of Traditional and Pictorial Symptom Scores among Indian Men with Lower Urinary Tract Symptoms: A Retrospective Observational Study

Eeshansh Khare

Introduction: The traditional questionnaire for Lower Urinary Tract Symptoms (LUTS) in males is the International Prostate Symptom Score (IPSS). To minimise its limitations, a picturebased Visual Prostate Symptom Score (VPSS) was developed as an alternative. Aim: To compare the ease of use, applicability, and clinical correlation of the Traditional Symptom Score (TSS) and Pictorial Symptom Score (PSS) among Indian men presenting with LUTS. Materials and Methods: This was a retrospective, recordbased observational s …

01.09.2026journal-article

Frontiers in Oncology

Case Report: Metastatic melanoma with initial ctdna decline and radiographic response during self-directed antiparasitic use: treatment effect or spontaneous regression?

Ricky Cheng, Daniel V. Araujo

A 74-year-old man with nodular melanoma of the right lateral neck presented with nodal and hepatic metastases at staging. He declined guideline-directed therapy and instead pursued lifestyle modifications alongside self-administered ivermectin and fenbendazole. On serial imaging, his disease initially demonstrated reduced metabolic activity and size without new sites of involvement, paralleled by a decline in tumor-informed ctDNA (Signatera) from 2.04 to 0.18 MTM/mL. Both subsequently worsened, with ctDNA rising to …

01.09.2026journal-article

Frontiers in Medicine

Risk factors and prediction model for mortality risk in older adults septic patients

Shao-Zhen He, Lu-Zhen Qiu, Yong-Xiang Li, Zhao-Bin Yang, Xiao-Mei Cheng

Background The early identification of septic patients at high risk of mortality is essential for improving clinical outcomes. This study aimed to investigate the risk factors associated with 28-day mortality among older adults septic patients admitted to the intensive care unit (ICU) and to develop a predictive model based on these factors. Methods A total of 165 older adults septic patients admitted to the ICU of our hospital between April 2022 and March 2025 were included in this study. Multivariate logistic reg …

01.09.2026journal-article

Sumatera Medical Journal

Patient Specific Titanium Implant Post Maxillectomy: The Evolution of Surgical Reconstruction

Jeeven Velayutham, Liew Yew Toong, Sakina Ghauth

Background: Malignancies arising from paranasal sinus account for 0.2-0.8% of all malignant neoplasms and 3% of the malignant neoplasms occurring in the head and neck. Surgical treatment of maxillary sinus carcinoma often consists of an open sub-total or total maxillectomy with a subsequent significant defect. Besides, the proximity of the maxillary sinus with complex anatomical structures make reconstruction a major challenge for head and neck surgeons. Reconstruction with temporalis myofascial flap along with tit …

01.09.2026journal-article

Frontiers in Neurology

Associations of nine composite inflammatory indices with clinical outcomes after mechanical thrombectomy for acute ischemic stroke: a single-center retrospective study

Min Yuan, Hui He, Longyi Zheng, Yueyue Tang, Shuang Tang, Jia Duan, Wenli Xing, Ao Qian

Objective This study aims to explore the associations of nine common composite inflammatory indices with hemorrhagic transformation (HT), unfavorable outcome, and all-cause mortality in patients with acute ischemic stroke (AIS) following mechanical thrombectomy (MT). Methods A retrospective study was conducted with composite inflammatory indices, including systemic immune-inflammation index (SII), systemic inflammation response index, pan-immune-inflammation value, neutrophil-to-lymphocyte ratio (NLR), platelet-to- …

01.09.2026journal-article

Frontiers in Cardiovascular Medicine

Regulatory mechanisms and interactions of mitophagy and ketone body metabolism in cardiac metabolism

Shujun Ding, Yuna Hu, Qin Zhang, Xinyi Liu, Xuan Zhao, Yajing Zhao, Wen Zhang

Cardiac function depends on tightly regulated energy metabolism, with mitochondria serving as key sites of cellular energy production. Mitophagy, a selective form of autophagy that maintains mitochondrial quality, has received growing attention for its role in cardiomyocyte metabolism. Under specific physiological and pathological conditions, the myocardium increases its use of ketone bodies as energy substrates, and ketone body metabolism is closely linked to mitochondrial function. However, the relationship betwe …

01.09.2026journal-article

Diagnostics

Urinary Biomarkers in Urological Oncology: From Biological Origin to Clinical Decision-Making—A Narrative Review

Aliya Nurmukhanbetova, Kassymkhan Sultanbekov, Khussan Umurzakov, Zie Gassanov, Altyn Duisenbayeva, Alimkhan Talas, Lazzat Shaikenova, Aidos Bolatov

Urinary biomarkers are promising tools in urological oncology because urine can be collected non-invasively and repeatedly during diagnosis, treatment, and surveillance. Despite extensive biomarker discovery, their adoption in routine practice remains limited. Biomarker performance depends not only on analytical accuracy but also on the clinical decision, anatomical route into urine, biological source of the signal, specimen fraction, and timing and conditions of sampling. This review evaluates urinary biomarkers a …

01.09.2026journal-article

Orthopaedic Surgery

Osteoarthritis Therapeutics: From Microenvironment Understanding to Regenerative Intervention—Current Advances and Future Perspectives

Yongbiao Meng, Shenghua Wu, Quanchun Liu

ABSTRACT Osteoarthritis (OA) is a prevalent, chronic degenerative joint disease characterized by progressive cartilage degeneration and impaired joint function. Its rising global incidence poses a significant health and socioeconomic burden. Traditional therapies primarily offer symptomatic relief but fail to halt disease progression and are associated with notable limitations. The contemporary understanding of OA pathogenesis has evolved from a model of mechanical wear to one emphasizing systemic imbalance within …

01.09.2026journal-article

Radiation

Adaptive Emergency Radiotherapy Using Diagnostic Computed Tomography Imaging: Initial Results from a Retrospective Geometric Evaluation and Clinical Considerations

Fabian Krause, Christian Felix Schulz, Iris Fandrich, Frank-André Siebert

Background: Radiotherapy commonly requires a computed tomography (CT) dataset for treatment planning. Artificial intelligence-supported radiotherapy systems now enable online adaptive workflows that reduce uncertainties resulting from the use of diagnostic instead of planning CT images. The aim was to identify patient groups that may particularly benefit from adaptive emergency treatments. Methods: In this retrospective exploratory study, 16 patients comprising 21 planning target volumes (PTVs) were evaluated. PTVs …

01.09.2026journal-article

Nurse Educator

Development of Metacognitive Strategies to Improve Performance in High-Complexity Clinical Tasks Among Nursing Students: An Experimental Study

L. Iván Mayor-Silva, Alfonso Meneses-Monroy, Marta M. Hernández-Martín, Domingo de Pedro, José Luis Mate-Muñoz, Guillermo Moreno

Purpose: This study evaluates the effect exerted by a metacognitive skills training program on nursing students’ metacognitive skills and their perception regarding mental workload in high-load clinical situations. Methods: An experimental design with control and experimental groups (1:1) was conducted with first- and fourth-year nursing students. The experimental group completed 2 high-load simulations with metacognitive training between them, while the control group only performed the simulations. Both groups rep …

01.09.2026journal-article

European Journal of Nuclear Medicine and Molecular Imaging

Comparative analysis of PSMA-RADS Version 2.0 versus bone uptake metastatic probability (BUMP) score for characterising focal bone uptake on [18F]PSMA-1007 PET/CT in prostate cancer – a multicentre evaluation

James Cairns, Salman Arain, Amarnath Challapalli, Amalia Stavropoulos, Tamir Ali, Daniel Ward, John Sage, Georgia Ionescu, Julien M. Y. Willaime, Russell Frood, Amit Bahl, George Petrides, Andrew Scarsbrook

Abstract Purpose Prostate-specific membrane antigen (PSMA) PET/CT is widely used in prostate cancer management, but unspecific bone uptake (UBU) remains a diagnostic challenge particularly with [18F]PSMA-1007. Bone uptake metastatic probability (BUMP) score - a composite imaging-clinical model, was compared with PSMA Reporting and Data System (PSMA-RADS, Version 2) for predicting skeletal metastases in UBU. Methods A real-world cohort of [18F]PSMA-1007 PET/CT scans performed at three tertiary cancer centres was ret …

01.09.2026journal-article

BMC Oral Health

Preferences for orthodontic treatment attributes among young adult malocclusion patients in Anhui, China: a discrete choice experiment

Fangyu Song, Dandan Yu, Shan Jiang, Yihui Li, Yuguang Liu, Wang Yao, Han Cheng, Jianguang Xu, Wenhua Xu, Lidan Wang, Yuanyuan Gu

Abstract Background Malocclusion is a common dental condition that affects both oral function and facial appearance, with substantial implications for psychological well-being and oral health-related quality of life. Despite continuing advances in orthodontic technology, evidence on patient preferences for the available treatment options remains limited. This study aimed to quantify preferences and willingness to pay (WTP) for key orthodontic treatment attributes among young adults with malocclusion in China. Metho …