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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Clinical Spectrum and Severity of Mycoplasma pneumoniae Infection in Children From a Rural Tertiary Centre: A Case Series

Ruchika Suresh Kannake, Smita Jategaonkar, Varsha Chauhan, Manish Jain

Mycoplasma pneumoniae, a common cause of Community Acquired Pneumonia (CAP) in children is traditionally considered a mild illness. Increasing evidence suggests broader clinical spectrum with significant respiratory and extrapulmonary involvement. This case series consists of 20 hospitalised children with laboratory-confirmed M. pneumoniae infection at rural tertiary care centre. Diagnosis was confirmed using respiratory Real-time Polymerase Chain Reaction (RT-PCR) in all patients, with serology performed in four c …

01.09.2026journal-article

Journal of the European Society of Surgery

Immediate Postoperative Recurrence of a Large Hiatus Hernia After Laparoscopic Nissen Fundoplication Without Suture Disruption: A Case Report

Manish Madnani, Kamran Khan, Shashi Tiwari, Suhail Kazim

Background: Recurrence of a repaired hiatus hernia after antireflux surgery is a well-recognised late complication, but recurrence within the first 24 hours, without disruption of the crural or wrap sutures, is exceptionally rare. Case Presentation: A 28-year-old man underwent laparoscopic Nissen fundoplication with hiatal repair for a large hiatus hernia with severe gastroesophageal reflux disease. Three crural sutures (Ethibond 2-0) were placed and a 360-degree wrap fashioned over a 40 French bougie, with the wra …

03.09.2026journal-article

Journal of Applied Clinical Medical Physics

Evaluation of inter‐fractional anatomical variations due to compression belt placement reproducibility using MR‐guided radiotherapy treatment fraction images

Olivia Shay, David Solis, Morgan Aire, Christopher Schneider, Krystal Kirby

Abstract Background Abdominal compression (AC) using a belt‐based system is widely employed in radiation therapy to limit respiration‐induced target motion for abdominal and hepatic malignancies. While AC has demonstrated efficacy in reducing intrafraction motion amplitude, the interfractional anatomical consequences of daily compression belt (CB) placement variability remain poorly characterized. A clearer understanding of this variability is necessary to determine whether online adaptive radiotherapy (oART) is re …

03.09.2026journal-article

Considerations in Medicine

Self-medication practices in the Santhal community: insights into knowledge, practices and attitudes

Sree Sudha T Y, Krishna Sasanka K S B S, Sumit Kumar Mahato, Kusum Kumari, Mamta Shukla, Kazi Afreen Jahan, Harminder Singh

Background To assess the prevalence, knowledge, practices and attitudes related to self-medication among the Santhal tribal community of Santhal Pargana, Jharkhand, India. Methods A community-based cross-sectional study was conducted with 102 participants from June to December 2024 among adults aged ≥20 years residing in villages served by primary health centres in Santhal Pargana. Participants who reported self-medication during the preceding 3 months were recruited using convenience sampling. Data were collected …

01.09.2026journal-article

Annals of Clinical and Analytical Medicine

Evaluation of the relationship between lifestyle factors and vitamin D levels in healthcare workers

Fatma Zehra Ağan, Çiğdem Cindoğlu, Velat Aytekin, Veysel Ağan

Aim This study evaluated the effects of lifestyle habits on serum 25(OH)D levels and the prevalence of vitamin D deficiency among healthcare workers. Methods In this retrospective study, laboratory and demographic data of 204 healthcare workers who attended the Internal Medicine outpatient clinic between January 1, 2023, and January 1, 2024, and had serum vitamin D levels measured were analyzed. Lifestyle factors, including sun exposure, clothing style, physical activity, smoking, and alcohol use, were assessed usi …

01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Exophytic Major Recurrent Aphthous Stomatitis (Fuchs Syndrome) Triggered by Pregnancy and Lactation: A Case Report

Mittal Sindhav, Bharat Chaudhary, Ronak Shah, Parth Shah

Fuchs syndrome, the most severe form of major Recurrent Aphthous Stomatitis (RAS), is characterised by large, deeply penetrating oral ulcers that cause significant morbidity. While its pathogenesis involves immune dysregulation, nutritional deficiency, and hormonal influences, pregnancy and lactation-associated exacerbations remain poorly documented, and atypical exophytic presentations are exceptionally rare. Hereby, the authors report the case of a 32-year-old lifelong lacto-vegetarian female, actively breastfeed …

01.09.2026journal-article

Frontiers in Immunology

Anti-CD38 monoclonal antibodies in multiple myeloma and beyond: immunotherapeutic mechanisms, evidence maturity, and clinical positioning

Liming Yu, Changnian Li, Dadong Guo, Siyuan Cui

Anti-CD38 monoclonal antibodies have become a central immunotherapeutic platform in multiple myeloma, where they have reshaped treatment across relapsed or refractory disease, frontline therapy, maintenance intensification, and minimal residual disease-oriented management. Their success in multiple myeloma has also stimulated broader development in immunoglobulin light-chain amyloidosis, selected hematologic malignancies, and humoral immune-mediated disorders. CD38 functions both as a surface target and as an ectoe …

01.09.2026journal-article

The Egyptian Journal of Internal Medicine

Clinical utility of α-glutathione S-transferase in hepatocellular injury: a review synthesis from clinical studies

John Derrick Chan

Abstract Background Early detection of hepatocellular injury remains a significant clinical challenge due to the limitations of conventional biomarkers such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which often rise only after substantial liver damage has occurred. α-Glutathione S-transferase (α-GST), a cytosolic enzyme highly expressed in hepatocytes, has emerged as a promising biomarker due to its rapid release and short plasma half-life, enabling earlier detection of liver injury. A …

01.09.2026journal-article

Peer Review

Are fluoroquinolones still viable for empirical UTI treatment? Evidence from southeastern Brazil

Patrícia Guedes Garcia, Janita Soraia de Oliveira Da Silva, Natália Maria da Silva Fernandes, Lucas Fernandes Suassuna, Luciana Debortoli de Carvalho, Taleessa Vieira Gomes, Ana Carolina Apolonio, André Luiz Silva Alvim, Marcio Roberto Silva

Urinary tract infections frequently require empirical antimicrobial therapy, although increasing fluoroquinolone resistance may limit their use. This retrospective cross-sectional study evaluated local susceptibility patterns and factors associated with resistance in urine cultures from outpatients attending a university hospital in southeastern Brazil during 2024. Of 1,958 cultures, 418 (21.35%) showed significant bacterial growth. Escherichia coli was the predominant pathogen (48.3%), followed by Klebsiella spp. …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Empathy and Ethics in Aesthetic Surgery: Between Medical Responsibility and Socially Constructed Beauty Ideals

Merima Kasumovic

Objective. To analyze the ethical, psychological, and social dimensions of contemporary aesthetic surgery, with particular emphasis on empathy in clinical decision-making, patient autonomy, body image disturbance, and the risks associated with unregulated practice. Narrative review. This manuscript is based on a qualitative narrative review of the literature in plastic surgery, bioethics, psychology, and public health, including professional guidance documents and selected epidemiological reports. Available evidenc …

01.09.2026journal-article

Mediterranean Journal of Hematology and Infectious Diseases

Fatal disseminated fusariosis during induction therapy for adult acute lymphoblastic leukemia in a patient with prior multiple myeloma

Sara Alberti, Gianluca Cavallaro, Alessandra Tebaldi, Paola Tebaldi, Maria Chiara Finazzi, Anna Grassi, Monica Galli, Laura Paris, Paola Stefanoni, Francesca Valsecchi, Alessandro Rambaldi, Federico Lussana

Invasive fungal infections are a major cause of morbidity and mortality in patients with hematologic malignancies, particularly during prolonged neutropenia and intensive chemotherapy. In acute lymphoblastic leukemia (ALL), prophylaxis is challenging because mold-active azoles interact with vinca alkaloids and may increase hepatotoxicity with asparaginase, whereas provide incomplete coverage against Aspergillus spp. and rare molds such as Fusarium spp. We report a fatal case of proven cutaneous invasive fusariosis …

01.09.2026journal-article

Health Affairs Scholar

Financing and Health System Capacity for Precision Medicine in Asia: A Six Country Landscape Analysis

Adena Li Tyin Peh, Yot Teerawattananon, Jeanette Xue Yan Yuen, Nordin Charafi, Dicky Levenus Tahapary, Jiahua Leng, Alec Morton, Sheyu Li, Woo Jin Kim, Bin Alwi Zilfalil, Hidayati Husainy Hasbullah, Nusara Satproedprai, Shao Tzu Li, Joanne Yuen Yie Ngeow, Yah Ru Juang, Yue Zhang, Minji Hong, Wenjia Chen

Abstract Background Precision medicine (PM) adoption is accelerating across Asia, but implementation remains uneven due to differences in financing, infrastructure, governance, and health-system readiness. Objectives To examine how six Asian countries (Singapore, South Korea, China, Malaysia, Thailand, and Indonesia) adopt, finance, and integrate PM technologies, and identify common implementation patterns and challenges. Methods A landscape review of peer-reviewed literature, government publications, and HTA repor …

01.09.2026journal-article

Microbiology Spectrum

Clinical impact of metagenomic next-generation sequencing for pathogen identification and guided therapy in pediatric intensive care unit patients with severe pulmonary infections

Yuping Xu, Ruijuan Ren, Weiqing Liu, Ling Liu, Xinyan Cui, Jia Guo, Shujun Li

ABSTRACT To explore the diagnostic efficiency, clinical concordance, and precision treatment value of metagenomic next-generation sequencing (mNGS) for severe pulmonary infections in children in the pediatric intensive care unit (PICU), and to provide evidence for improving microbiological diagnosis and optimizing anti-infective strategies. A retrospective cohort study included 89 children with severe pneumonia in the PICU in 2024. All underwent routine microbiological testing and mNGS of bronchoalveolar lavage flu …

01.09.2026journal-article

Health Science Reports

Epidemiological and Clinical Profile of Cleft Lip and/or Palate in Mbujimayi: A Cross‐Sectional Study

Trésor Kabuya Kabamba, Eugène Mukeba Bamusua, Pascal Cimpaka Kabeya, Pascal Kayembe Shambuyi, Micheline Nyembo Epupwa, Didier Mubenga Katende, Séraphin Binene Katulondi, Henry‐Benjamin Tshimanga Kabeya, Jenny Nshimba Kabemba, Joël Manyonga, Joseph Luboya Kabila, Hubert Kabanga Ngandu, Roger Kamwema Shamuana, François Kabumba Kabumba

ABSTRACT Background and Aim Cleft lip and/or palate (CLP) is the most common craniofacial malformation worldwide, with significant geographic and socioeconomic disparities. In Mbujimayi, DRC, no prior data have been published on its prevalence or clinical presentation. This study aimed to determine the epidemiological and clinical profile of CLP in Mbujimayi. Methods This was a cross‑sectional study conducted at the University Clinics of Mbujimayi between March 2023 and July 2025. A total of 54 patients with CLP we …

01.09.2026journal-article

International Journal of Sports Physical Therapy

Adductor-Related Athletic Groin Pain: A Clinical Commentary

Derrick Larkins, Robert Rowland, Michael Zarro, Odessa Addison

Adductor-related athletic groin pain (ARAGP) is a common condition in athletes participating in multidirectional, high-intensity sports. It is challenging to diagnose and manage due to complex regional anatomy and overlapping clinical presentations. ARAGP represents the most frequently reported subtype of athletic groin pain and contributes substantially to time loss from play and performance limitation. This clinical commentary synthesizes current evidence related to the anatomy, risk factors, pathomechanics, imag …

01.09.2026journal-article

Discover Social Science and Health

Understanding patient preferences for private healthcare services among the general Hungarian adult population using discrete choice experiment

Balázs Kertesz, Klára Bíró, Péter Balogh

Abstract As private healthcare plays an increasingly prominent role in Hungary’s dual healthcare system, understanding patient preferences has become essential for health policymakers and healthcare providers. Background data indicate significant underfunding in Hungary’s public healthcare system, leading to long waiting times and limited access—key drivers of private-sector growth. This study investigates attributes associated with stated choice in private healthcare settings using a discrete choice experiment wit …

01.09.2026journal-article

American Journal of Critical Care

Effect of a Machine Learning Algorithm to Guide Goal-Directed Therapy After Cardiac Surgery

Amanda Rea, Alexandra Deasel, Clifford Edwin Fonner, Rawn Salenger

Background Goal-directed therapy allows clinicians to optimize perfusion and volume status in patients postoperatively. Objective To evaluate the effect of a machine learning algorithm to guide postoperative goal-directed fluid therapy in cardiac surgery patients. Methods A goal-directed fluid therapy program was implemented in a single center for coronary artery bypass patients with ejection fraction greater than or equal to 45% (implementation period: May 15, 2023, to May 31, 2024). Patient outcomes were compared …

01.09.2026journal-article

Journal of Iranian Medical Council

Health Professionals’ Responses to Patient Gift-Giving

Shahriar Mousavinejad, Erfan Mahjoob Khaligh, Mirsaeed Attarchi, Kourosh Delpasand

Background: Healthcare professionals› acceptance of gifts poses ethical dilemmas, potentially biasing clinical decisions and eroding public trust. The aim of this study is to investigate the prevalence, motivations, and responses to gift-giving among healthcare staff. Methods: An analytical cross-sectional study was conducted at Razi Hospital, Rasht, from January to June 2024. Convenience sampling was used to recruit physicians, nurses, and residents. A valid questionnaire was used to collect data. The validity was …

01.09.2026journal-article

Frontiers in Surgery

Postoperative structured nursing plan for patients with cervical spine fracture and spinal cord injury: a retrospective study

Ni Luo, Aijun Xu, Shanshan Xu, Bo Chen, Yunlin Chen, Xudong Hu, Jing Li

Objective This study aimed to examine the efficacy of structured nursing in promoting postoperative recovery among patients with cervical spine fracture and spinal cord injury. Methods This study is a retrospective cohort analysis. A total of 100 patients with cervical spine fracture and spinal cord injury who underwent anterior cervical discectomy and fusion (ACDF) at our Hospital from December 2023 to December 2025 were included as the research subjects. They were divided into control group (Routine nursing, n = …

01.09.2026journal-article

Frontiers in Medicine

An immune-inflammatory dysregulation score for risk stratification of 28-day all-cause mortality in critically ill patients with severe community-acquired pneumonia

Shulan Zhou, Bin Fu, Ziyi Huang, Hanqi Wang, Yongjian Pei, Chen Chen, Tong Zhou, Zengli Zhang

Background Severe community-acquired pneumonia (SCAP) is associated with high mortality and substantial heterogeneity in host immune responses among critically ill patients. Conventional prognostic scores primarily reflect comorbidity burden and organ dysfunction but do not directly capture immune dysregulation. Methods This retrospective cohort study included 223 critically ill patients with SCAP admitted to the respiratory intensive care unit (RICU). Six prespecified immune-inflammatory biomarkers were evaluated …

01.09.2026journal-article

International Journal of Legal Medicine

Biological matrices for determining the origin of post-mortem ethanol: Recommendations for collection and storage

Allane Patricia Santos da Paz, Luiz Basílio Bouzas Nunez, Vanessa Jóia de Mello

Abstract Ethanol is one of the most widely used psychoactive substances worldwide and one of the most frequently investigated substances in forensic toxicology laboratories. Choosing the most appropriate biological sample for its screening is extremely important in forensic autopsy, mainly to differentiate alcohol consumed before death from alcohol formed post-mortem , as well as to reduce the risk of ethanol loss through oxidation or metabolism. Therefore, this study presents an integrative review of recent litera …

01.09.2026journal-article

Journal of Medicine Pharmacology and Medical Devises Technology

Bridging Biochemistry and Tumour Biology: LDH and CRP–Albumin Ratio in Relation to Ki-67 and Histological Aggressiveness of Breast Carcinoma

Abhinadan Greeg, Bora Sukesh

Background: Breast carcinoma exhibits considerable biological heterogeneity, and inexpensive circulating biomarkers capable of reflecting tumour aggressiveness may complement conventional pathological assessment. This study evaluated serum lactate dehydrogenase (LDH) and CRP–albumin ratio (CAR) in relation to histopathological features and Ki-67 proliferation. Methods: This prospective clinicopathological study included 128 treatment-naïve patients with primary breast carcinoma. Pretreatment serum LDH, CRP and albu …

01.09.2026journal-article

Journal of Patient-Reported Outcomes

Psychometric validation of the Persian version of the howRwe questionnaire: a cross-sectional study

Mohammad Gholamnezhad, Leila Ghamkhar, Nezam Armand, Mohammad Effatpanah, Tim Benson, Mojtaba Sedaghat, Samane Hajiabbasi, AmirAli Ghamkhar, Seyed Yasin Yazdi-Amirkhiz, Maryam Ghamkhar

Abstract Background The howRwe questionnaire is a brief measure of patient experience that has not been adapted for Persian-speaking populations. This study aimed to translate, culturally adapt, and psychometrically validate the Persian version of the howRwe questionnaire (P-howRwe). Methodology This single-center cross-sectional study was conducted in two phases: translation/cultural adaptation and psychometric validation. Following forward and backward translation, an expert committee reviewed the translated vers …