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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

The International Journal of Comprehensive Health, Medicine, & Dentistry

Knowledge, Attitudes, and Practices Regarding Antibiotic Use and Resistance Among Medical Students in Pakistan: A Cross-Sectional Study

Muhammad Nouman, Samman Malik, Arshia Arshad, Fatima Riaz, Zunaira Shahzad, Laeeba Iqbal

Background: Antibiotic resistance is a major global public health challenge, fueled in part by the inappropriate use of antibiotics among healthcare professionals and medical students. As future prescribers, medical students constitute a key target for educational interventions because their knowledge, attitudes, and prescribing practices are developed during undergraduate medical education. Objectives: To evaluate the knowledge, attitudes, and practices (KAP) related to antibiotic use and antimicrobial resistance …

03.09.2026journal-article

Veterinary Medicine and Science

Genetic Diversity and Population Structure of Zambian Indigenous Cattle

Ellison Musimuko, King Shimumbo Nalubamba, Victor Chisha Zulu, Idowu Kolawole Odubote, Walter Muleya

ABSTRACT A study was conducted to determine the genetic diversity of Zambian indigenous cattle using microsatellites. In Zambia, cattle provide draft power, food, manure and generate income. DNA extraction followed the Qiagen protocol, and Arlequin V3.0 was used for data analysis. 72 unrelated animals from three regions, Eastern (Angoni), Southern (Tonga) and Western (Barotse), were sampled. 315 alleles observed were higher in TGLA 263 (106 bp) with 0.861, 0.824 and 0.753, BMS650 (160 bp) with 0.710 and SPS 115 (24 …

01.09.2026journal-article

ACR Open Rheumatology

Fracture Risk Associated With Long‐Term Discontinuation of Postmenopausal Osteoporosis Treatment: A French Population‐Based Study Using National Claims Data (Système National des Données de Santé)

Audrey Lajoinie, Meriem Benmerad, Magali Laborey, Pascale Samama, Gaëlle Désaméricq, Leila Chelbani, Karine Briot

Objective This retrospective cohort study evaluated the long‐term discontinuation (LTD) of osteoporosis treatments in postmenopausal women in France and associated fracture risk and economic burden. Methods From the national French health care database (Système National des Données de Santé), we included postmenopausal women aged ≥60 years initiating oral bisphosphonates, intravenous bisphosphonates, or denosumab between 2012 and 2015 with three or more (bisphosphonates) or two or more (denosumab) years of continuo …

01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Status Epilepticus as the Initial Presentation of Neurofibromatosis Type 1 in a Three-Year-Old Male: A Case Report

M Swetha, Smita Dey, Jayakaviyah .

Neurofibromatosis Type 1 (NF1) is a common autosomal dominant neurocutaneous disorder, occurring in approximately one in 2,500-3,000 live births. It results from mutations in the NF1 gene and is characterised by diverse cutaneous, ophthalmologic, and neurological manifestations. Although seizures occur in 4-10% of affected children, status epilepticus as the initial presentation in early childhood is uncommon. In present case, a three-year-old boy presented with continuous abnormal body movements and unresponsivene …

01.09.2026journal-article

Journal of Acute Care Pharmacotherapy

Ethical Issues Associated with New Technologies in Patient Care

Brian Erstad

The purpose of this paper is to discuss ethical issues raised by new technologies such as artificial intelligence tools that could occur now or in the future with ongoing innovations. After a brief mention of terminology, five concerns associated with new technologies are presented that have associated ethical implications. Following this is a discussion of the implications of concerns for various stakeholders with additional references for the interested reader.

01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Impact of COPD Phenotype on Disease Specific HR-QoL using CAT and SGRQ-C Score: A Hospital-based Observational Study

Naresh Bhagora, Sher Singh Meena, Pushpendra Bairwa, Hitendra Jatav

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of morbidity and mortality worldwide. The chronic and progressive nature of the disease significantly affects patients’ Quality of Life (QoL). Tools like the COPD Assessment Test (CAT) and St. George’s Respiratory Questionnaire (SGRQ-C) are widely used to assess HealthRelated Quality of Life (HR-QoL) in these patients. Aim: To determine the impact of COPD phenotypes on diseasespecific HR-QoL using CAT and SGRQ-C score. Materials a …

01.09.2026journal-article

Physician Leadership Journal

From Volatility to Value: How Healthcare Leaders Can Fortify Supply Chain Strategy in 2026

Carolyn Howard

Supply chain management has never been a simple discipline, but the convergence of forces now shaping the healthcare landscape — regulatory upheaval, tariff instability, persistent inflation, and accelerating care migration — has elevated it to a strategic imperative at the executive level. For health system leaders, the question is no longer whether supply chain deserves a seat at the leadership table. The question is how quickly that seat can be secured and how effectively it can be used. This column examines the …

01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Cyberchondria and its Correlation with Depression among Parents of Underfive Children in an Urban Community of Tamil Nadu, India: A Cross-sectional Study

SU Bhavan Kumar, K Bincy, R Diwakar, P Kaveri, MVM Pradeep

Introduction: Cyberchondria is characterised by an increase in health-related distress or anxiety, reassurance-seeking behaviour and frequent excessive online health searches. Parents are more vulnerable to this habit because they are likely to look up not just their own illness, but also their children’s. Aim: To determine how common depression and cyberchondria are among urban parents of under-five children in Tamil Nadu, as well as the factors associated with these conditions. Materials and Methods: A community- …

01.09.2026journal-article

Journal of Sports Science and Medicine

Beyond Traditional Metrics: A Systematic Review of Spatial and Spatiotemporal Indicators in 5-on-5 Basketball

Yana Liu, Wenlong Zhang, Mingquan Zhang, Qi Su, Xiao Xu

Basketball performance analysis has traditionally relied on event-based statistics and box-score-derived metrics. Although these measures describe performance outcomes, they provide limited information about how actions are shaped by player location, movement, and interaction during play. With the growing availability of court-referenced player and ball location data, spatial and spatiotemporal indicators have become increasingly common for describing game behavior in basketball. For the purposes of this review, sp …

01.09.2026journal-article

Eye & Contact Lens: Science & Clinical Practice

Moraxella nonliquefaciens Keratitis Due to Ocular Surface Disease in a Patient Treated with Zanubrutinib for Mantle Cell Lymphoma

Ori Stern, Haggay Avizemer

Abstract: Zanubrutinib, a second-generation Bruton tyrosine kinase inhibitor used in B-cell malignancies, has a favorable systemic safety profile, whereas its ocular surface effects remain insufficiently defined. We report a 73-year-old woman receiving zanubrutinib for mantle cell lymphoma who presented with acute pain and decreased vision in the right eye. Slitlamp examination revealed a corneal epithelial defect with an associated stromal infiltrate in the right eye and bilateral epithelial surface abnormalities. …

01.09.2026journal-article

Clinical and Experimental Reproductive Medicine

Average oocyte quality index as a method for scoring dysmorphic oocytes in women with ovarian endometrioma undergoing in vitro fertilization and its correlation with ovarian reserve

Ju Hee Park, Seul Ki Kim, Byung Chul Jee

Objective: This study investigated whether the average oocyte quality index (AOQI), used as a dysmorphic oocyte scoring system, is higher in women with ovarian endometrioma than in those with unexplained infertility or diminished ovarian reserve (DOR).Methods: We included 92 intracytoplasmic sperm injection cycles in which one to five metaphase II oocytes were obtained, and the AOQI was calculated in each cycle. Cycles were grouped according to the indication for in vitro fertilization: current or recurrent endomet …

01.09.2026journal-article

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Spontaneous Endometrial Cast Expulsion in Membranous Dysmenorrhoea: A Case Report

Swapnali Sansare, Aneesha Nallapati

Membranous dysmenorrhoea is a rare gynaecological condition characterised by the expulsion of the endometrium as a single intact cast that retains the shape of the uterine cavity. The authors report the case of a 36-year-old multiparous female who presented with a history of heavy and prolonged menstrual bleeding associated with the passage of tissue per vaginum for 7-8 months. She had a preceding history of amenorrhoea for six months and pregnancy was excluded. Clinical examination revealed expulsion of a membrano …

01.09.2026journal-article

Journal of Cataract & Refractive Surgery

Long-term outcomes of corneal crosslinking for keratoconus across pediatric, adolescent, and adult populations in a diverse U.S. population

Karen M. Chen, Thitima Wungcharoen, Cindy Zhao, David Myung, Edward E. Manche

Purpose: To evaluate long-term outcomes of epithelium-off corneal crosslinking (CXL) on keratoconus progression and visual function across pediatric, adolescent, and adult cohorts in a diverse U.S. population over a 5-year follow-up period. Setting: Tertiary care ophthalmology center in the United States. Design: Retrospective cohort study conducted between January 2017 and October 2025 of patients treated between January 2017 and May 2023. Inclusion criteria required a diagnosis of progressive keratoconus and ≥12 …

01.09.2026journal-article

Journal of Cataract & Refractive Surgery

Neuroprotective and anti-inflammatory strategies for corneal nerve regeneration and ocular surface stability after corneal refractive surgeries: systematic review

Anas Alamoudi, Abdulaziz Khalid Aldahlawi, Ahmed Alnabihi, Rozan Abdulaziz AlGhamdi, Hind Mohammed Aljabri, Naif Almufarriji, Rahaf Khder Sharif, Danah Albreiki, Bader AlQahtani

Topic: This study aimed to systematically synthesize and critically appraise all controlled trials evaluating neuroprotective and anti-inflammatory pharmacotherapies for enhancing corneal nerve regeneration and ocular surface stability after corneal refractive surgeries. Clinical Relevance: Postrefractive surgery dry eye and hypoesthesia are common and often persistent, underscoring the need for evidence-based pharmacologic strategies to promote corneal nerve recovery and tear film stability. Methods: The authors r …

01.09.2026journal-article

Archives of Hand and Microsurgery

Mid-term clinical and radiographic outcomes of PyroDisk interposition arthroplasty for thumb carpometacarpal arthritis: a retrospective case series

Ji-Won Lee, Yang-Guk Chung, Jaehak Lim, Youn-Tae Roh

Purpose: Osteoarthritis of the thumb carpometacarpal (CMC) joint is one of the most common hand conditions requiring surgery and predominantly affects postmenopausal women. No surgical technique has consistently demonstrated superiority. The PyroDisk (Integra LifeSciences) interposition implant preserves trapezial bone stock and thumb length, with favorable survival rates reported in Western cohorts; however, data from Asian patients remain limited.Methods: We retrospectively analyzed 33 joints in 32 women with Eat …

01.09.2026journal-article

Journal of Cataract & Refractive Surgery

Visual and refractive outcomes with intrascleral haptic fixation of the light adjustable lens

Allison J. Chen, Emily Grace Rodgers, Li Wang, Douglas D. Koch, Christina Y. Weng, Zaina N. Al-Mohtaseb

Purpose: To describe refractive outcomes with intrascleral haptic fixation (ISHF) of the light adjustable lens (LAL). Setting: Baylor College of Medicine and 1 private practice in the United States. Design: Retrospective sequential cohort. Methods: All patients undergoing double-needle ISHF of the LAL were included in the study. Pretreatment and post-lock-in uncorrected distance visual acuity (UDVA) were recorded. Mean numerical errors, refractive prediction errors, and astigmatism outcomes were measured. Results: …

01.09.2026journal-article

Journal of Clinical Investigation

Mechanosensitive phosphorylation of NFATC4 at S213/S217 drives fibroblast-to-myofibroblast transition and fibrosis

Safwen Kadri, Laura F. Mattner, Zhen Zeng, Sai Rama Sridatta Prakki, Arun Kumar Verma, Umut Cetin, Christoph H. Mayr, Meshal Ansari, Xin Wei, Sara Asgharpour, Anita A. Wasik, Nikolaus Kneidinger, Mircea-Gabriel Stoleriu, Jürgen Behr, Julien Polleux, Ali Önder Yildirim, Laurens J. De Sadeleer, Wim A. Wuyts, Gerald Burgstaller, Matthias Mann, Martin Mück-Häusl, Herbert B. Schiller

Mechanosensitive feedback between tissue stiffness and cellular contractile forces instructs cell identity. To characterize phosphorylation-mediated mechanosensing, we charted the global phosphoproteome dynamics of primary human lung fibroblasts on fibronectin-coated polydimethylsiloxane substrates of defined stiffness. We identified a key signaling threshold at 2–8 kPa, above which cells activated cytoskeletal remodeling, ECM secretion, and transition to a CTHRC1 + / ACTA2 + myofibroblast state, accompanied by sti …

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01.09.2026journal-article

Frontiers in Environmental Chemistry

Vetiver biochar application for heavy metal sequestration in water treatment: bridging perfumery waste and environmental sustainability

Sameer Neve, Viravid Na Nagara, Zhiming Zhang, Rupali Datta, Dibyendu Sarkar

Converting industrial byproducts into functional adsorbents supports circular and sustainable approaches to water treatment. This study evaluated biochar derived from spent vetiver ( Chrysopogon zizanioides ) roots, a byproduct of the perfumery essential-oil industry, for the competitive adsorption of copper (Cu), cadmium (Cd), zinc (Zn), and lead (Pb). Vetiver root biochar produced at 500 °C for 60 min exhibited a high surface area of 308.2 m 2 /g and a yield of 53.8%. Batch adsorption experiments were performed i …

01.09.2026journal-article

Frontiers in Endocrinology

Clinical evaluation and predictive model development of AI-based non-invasive embryo selection in in vitro fertilization patients

Pengfei Zhu, Xingyu Bi, Dan Su, Xumin Zhang, Xueqing Wu

Background Embryo selection remains one of the most critical determinants of IVF success. Conventional embryo grading relies primarily on morphological assessment and is subject to inter-observer variability and limited predictive accuracy. Recent advances in AI have enabled non-invasive systems to analyze embryological and morphokinetic features, improving embryo selection and reproductive outcomes. Objective To evaluate the clinical effectiveness of an AI-based non-invasive embryo selection system and develop pre …

01.09.2026journal-article

Jurnal Kesehatan dan Kedokteran

Demographic, Clinical, and Antibiotic Exposure Factors Associated with Carbapenem-Resistant Acinetobacter baumannii: An Eight-Year Retrospective Study

Angky Budianti, Dzaki Fadlurrahman Ayyasy, Mubarokah Mubarokah, Victor Sitorus, Yulia Rosa Saharman, Budiman Bela, Anis Karuniawati

Antimicrobial resistance is a major global health challenge, and carbapenem-resistant Acinetobacter baumannii (CRAB) is of particular concern because of its high level of resistance, limited therapeutic options, and substantial burden in healthcare-associated infections. Identifying patient characteristics and antibiotic exposure associated with CRAB is essential to support effective antimicrobial stewardship and infection prevention strategies. Objective: This study aimed to analyze the association of demographic …

01.09.2026journal-article

Mediterranean Journal of Hematology and Infectious Diseases

Magnusiomyces capitatus Breakthrough Infection in Allogeneic Hematopoietic Cell Transplant Recipients Receiving Echinocandin Prophylaxis: Clinical Features, Management, and Review of the Literature

Claudia Gomez-Hernandez, Carmen Corrales, Pedro José Mirete, Soraya Ramos, Mireia Micó-Cerdà, Clara Martinez-Lopez, Juan Carlos Hernandez-Boluda, Carlos Solano, Rafael De la Camara, Jose Luis Piñana

Magnusiomyces spp. infections are an uncommon but highly lethal emerging mycosis in immunocompromised patients, particularly those with hematologic malignancies and profound neutropenia. Data in the setting of allogeneic hematopoietic cell transplantation (allo-HCT) remain scarce. These infections typically occur early after transplantation as breakthrough events under antifungal prophylaxis and are associated with high mortality despite appropriate therapy. In this study, we report two concurrent cases from two Sp …

01.09.2026journal-article

Lux Médica

Amaurosis bilateral transitoria como manifestación inicial del síndrome de encefalopatía posterior reversible (PRES) en una paciente con preeclampsia con criterios de severidad.

Marisol López Lizarraga, Carolina Durán Andrade

Introducción: La preeclampsia con criterios de severidad puede asociarse con complicaciones neurológicas graves, entre ellas el síndrome de encefalopatía posterior reversible (PRES), una entidad poco frecuente que puede manifestarse con alteraciones visuales agudas como amaurosis bilateral transitoria. Objetivo: Describir la presentación clínica, abordaje diagnóstico, manejo y evolución de una paciente con amaurosis bilateral secundaria a PRES en el contexto de un trastorno hipertensivo del embarazo. Métodos: Se pr …

01.09.2026journal-article

Egyptian Journal of Radiology and Nuclear Medicine

Beyond conventional MRI: diagnostic utility of diffusion and ADC mapping in seronegative spondyloartropathy

Lamiaa Arafat, Afaf Abd-Elkader Hassan, Samar H. Goma, Marwa Makboul, Shimaa Farghaly

Abstract Background Seronegative spondyloarthropathies represent a broad spectrum of inflammatory disorders that affect articular and extra-articular structures. MRI is considered the gold standard for diagnosing sacroiliitis. Our study aims to evaluate the added advantages of DWI and ADC value over STIR in identifying acute sacroiliitis among seronegative spondyloarthropathy patients. Methods Seventy-five patients with clinically suspected acute seronegative spondyloarthropathy were included. Laboratory investigat …

01.09.2026journal-article

Metabolites

Advances in Exercise-Mediated Regulation of the Gut Microbiota via the Muscle–Gut Axis: Implications for Tumor Immunity and Treatment Responses

Tao Pang, Xinyi Zhou, Zhe Ge

The gut microbiota can influence tumor immunity and treatment responses through microbial metabolism, intestinal barrier regulation, and immune–inflammatory signaling, but whether exercise engages these mechanisms through the muscle–gut axis remains uncertain. This review integrates evidence from exercise physiology, microbial metabolism, and tumor immunology to examine how exercise-associated host signals may reshape the intestinal ecological niche and microbial function. Three candidate muscle–gut axes are propos …