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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
24.08.2026journal-article

Frontiers in Dental Medicine

Assessing the environmental impact of clear aligner therapy: a scoping review

Sapthami Pai, Dhruv Ahuja, Ashith MV, Haneesh Kiran PT, Amoli Singh

Objective To evaluate the environmental impact and sustainability-related practices of clear aligner therapy (CAT), focusing on environmental impact, economic implications, waste management, recycling practices, manufacturing processes, and aligner materials. It further explores the alignment of clear aligner practices with Sustainable Development Goals (SDG's) 3,9,12 and 13. Methodology A scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Sco …

24.08.2026journal-article

Physics in Medicine & Biology

Towards a clinically practical computational platform for systematically adapting radiation therapy for glioma patients

Hugo J M Miniere, David A Hormuth, Ernesto A B F Lima, T J Whitaker, Maguy Farhat, Bikash Panthi, Holly Langshaw, Mihir D Shanker, Wasif Talpur, Sara Thrower, Jodi Goldman, Caroline Chung, Thomas E Yankeelov

Abstract Objective. High-grade gliomas (HGG) are aggressive brain tumors with poor prognoses despite an intense standard-of-care (SOC) chemoradiation protocol. Radiotherapy (RT) guidelines use static dose maps, which may not fully account for intratumoral heterogeneities and areas of tumor progression over the course of treatment. We address this limitation by guiding radiation delivery using imaging data to identify proliferative areas which are then targeted by a dose boost, and use mathematical modeling to simul …

24.08.2026journal-article

British Journal of Radiology

Systematic review: Stereotactic Body Radiation Therapy for Pancreatic Cancer: Evaluating its Efficacy, Safety, and Future Prospects

Biplab Sarkar

Abstract Aim This systematic narrative review evaluates the efficacy, safety, and future potential of Stereotactic Body Radiation Therapy (SBRT) in locally advanced pancreatic cancer (LAPC), particularly for patients unsuitable for surgery. Methods A systematic search of PubMed, Embase, and the Cochrane Library identified English and select non-English studies published between January 2010 and November 2025. Search terms included “pancreatic cancer,” “SBRT,” “locally advanced pancreatic cancer,” “adaptive radiothe …

24.08.2026journal-article

International Journal of Basic & Clinical Pharmacology

Are physiotherapy students meeting their professional demands? A cross-sectional correlational study

Priyanka C. Chovatiya, Nikita Rathod, Mamta Rani, Dhwanit Shah

Background: The physiotherapy profession demands strength, endurance, and flexibility, yet the preparedness of students is uncertain. This study assessed the relationship between self-perceived and measured fitness and described exercise behaviours and musculoskeletal complaints among physiotherapy students. Methods: A cross-sectional correlational study of 127 students at the Government Physiotherapy College, Surat (October-November 2018). Self-perceived fitness was measured with a modified five-factor questionnai …

24.08.2026journal-article

Applied Sciences

TECAR Therapy Combined with Proprioceptive Neuromuscular Facilitation for Adhesive Capsulitis: An Exploratory Comparison of Two Multimodal Rehabilitation Programs on Pain, Disability, and Shoulder Mobility

Dan Alexandru Szabo, Silvia Teodorescu, Aura Bota, Adina Stoian, Adrian Gligor, Cristina Veres, Alexandru Rareș Puni, Denisa Elena Hăşmăşan, Dionisie Vladimir Turcu, Ioan Sabin Sopa

Adhesive capsulitis is characterized by shoulder pain, stiffness, and limited range of motion. Although multimodal rehabilitation is commonly used, it is unclear which combination of physiotherapy interventions is optimal. The aim of this exploratory study was to compare the short-term effects of TECAR therapy combined with proprioceptive neuromuscular facilitation (PNF) with those of standard physiotherapy in women with stage II adhesive capsulitis. This was a prospective, longitudinal, non-randomized, and explora …

24.08.2026journal-article

Clinical Pediatrics

Successful Therapy of CNS Tuberculosis With Granulomatous Inflammation in Immunodeficiency

Deniz Cagdas, Rahsan Gocmen, Gamze Sonmez, Aysegul Akarsu, Cagkan Inkaya, Ilkay Isikay

Central nervous system (CNS) tuberculosis (TB) carries high mortality and neurologic sequelae, especially when unrecognized inborn errors of immunity are present. We report a young woman with refractory TB meningitis, multiple intracranial tuberculomas, hydrocephalus, and intracranial hypertension despite 10 months of standard anti-TB therapy and corticosteroids. Severe vomiting led to poor adherence and severe weight loss. As immunologic evaluation suggested atypical combined immunodeficiency (CID); monthly intrav …

24.08.2026journal-article

Stem Cell Research & Therapy

Mesenchymal stromal cells for periventricular hemorrhagic infarction in extremely preterm infants: a double-blinded randomized controlled phase IIa clinical trial

So Yoon Ahn, Kwangsun Yoo, Yae Ji Kim, Chae Young Lim, Misun Yang, Se In Sung, Yun Sil Chang, Won Soon Park

Abstract Background Periventricular hemorrhagic infarction in extremely preterm infants (PVHI; the most severe form of intraventricular hemorrhage) are associated with a high risk of mortality and neurodevelopmental disability with no effective treatments. We aimed to assess the safety and potential efficacy of mesenchymal stromal cells (MSCs) for PVHI in preterm infants. Methods We conducted a single-center, phase 2a double-blind randomized controlled trial at the Samsung Medical Center. Twenty-two preterm infants …

24.08.2026journal-article

Sultan Qaboos University Medical Journal

Association Between Pain Catastrophising and Functional Limitation in Patients With Knee Osteoarthritis: A cross-sectional study in a Tunisian rehabilitation setting

Soumaya Elarem, Ikram Haddada, Ameni Ameur, Ferdaous Blel, Nedra El Feni, Aymen Fekih, Aymen Haj Salah, Mouna Sghir, Wassia Kessomtini

Objectives: Knee osteoarthritis (KOA) is a common reason for consultation in rehabilitation settings, responsible for pain and restricted autonomy. This study aimed to determine the association between catastrophising and functional limitation in patients followed for KOA in physical medicine and rehabilitation. Methods: This cross-sectional analytical study was conducted from June to August 2025 at the Department of Physical Medicine and Functional Rehabilitation in Taher Sfar University Hospital, Mahdia, Tunisia. …

24.08.2026journal-article

South African Journal of Arts Therapies

A Narrative Reflection on 22 Years in Music Therapy Practice in South Africa

Karen De Kock

This narrative reflection traces 22-years of music therapy practice in South Africa, encompassing my clinical work in a non-profit residential home for persons with profound intellectual disabilities and therapeutic group work in private psychiatric hospitals as well as work in corporate well-being and clinical supervision and teaching in higher-education . The journey explores how advocacy for the profession intersected with clinical practice, leading to the creation of a full-time post, staff support programs, ex …

24.08.2026journal-article

Australian Journal of Islamic Studies

Group-Based Cognitive Behavioral Play Therapy for Emotional and Behavioral Problems Among Pakistani Muslim Adolescents

Sheeza Sarfaraz, Tahira Yousaf

Muslim teenagers are increasingly experiencing emotional and behavioural problems (EBPs), which frequently go undiagnosed and may contribute to subsequent mental health issues. This pilot study was conducted with Pakistani Muslim adolescents in an urban school in Karachi. This study examined the efficacy of Cognitive Behavioral Play Therapy (CBPT) in reducing EBPs among Pakistani Muslim early and middle adolescents. Thirty-two students were screened; eight withdrew, resulting in a final sample of 24 participants ag …

24.08.2026journal-article

F1000Research

The Architecture of Sovereign Narrative Therapy (SNT): A Predictive Processing Framework for Symbolic Reorganization and Narrative Identity Revision

Gary Ow

Background Narrative and psychodynamic therapies have long emphasized the therapeutic value of metaphor, imagery, embodiment, and symbolic enactment. However, the mechanisms through which these processes contribute to enduring identity-level change remain incompletely specified. This paper presents Sovereign Narrative Therapy as a predictive processing framework that explains how symbolic interventions may support recursive narrative and identity transformation. Methods The paper develops a conceptual synthesis int …

24.08.2026journal-article

Transplantation Direct

Immune Checkpoint Inhibitor Therapy of Malignancy in Kidney Transplant Recipients: Analysis of Real-world Outcomes

Ali Rezazadeh, Elena-Bianca Barbir, Mohamed A. Aboelatta, Claudia-Denise Haivas, Shahin Kavousi, Byron H. Smith, Aleksandra Kukla, Arkadiusz Z. Dudek

Background. The use of immune checkpoint inhibitors (ICIs) in kidney transplant recipients (KTR) for cancer treatment is limited by concerns of allograft rejection and uncertain oncologic efficacy. Methods. We conducted a single-center retrospective study of KTR with unresectable or metastatic malignancies treated between 2018 and 2025. The primary study cohort included 33 patients treated with ICI, whose outcomes were compared with 20 matched KTR treated with non-ICI systemic chemotherapy (SC). Results. KTR treate …

24.08.2026journal-article

ACS Applied Materials & Interfaces

Carrier-as-Prodrug Glycyrrhizic Acid Nanogel Co-Delivers Mannose and Glycyrrhetinic Acid for Metabolic-Ionic Cancer Therapy

Bixi Sun, Zhu Jin, Alice Shen Yishan, Bingshu Liang, Chenming Zou, Chenfeng Wang, Yiming Qi, Yiyang Xia, Derong Cui, Yuanyuan Shen, Shengrong Guo

Abstract Cancer cells evade conventional therapies by dynamically switching between glycolysis and oxidative phosphorylation (OXPHOS). Simultaneous blockade of both pathways could overcome this plasticity but requires coordinated delivery of two inhibitors to the same cell. Here we design a glycyrrhizic acid (GA) nanogel that functions as both a structural carrier and a prodrug. GA itself serves as the structural carrier. It hydrolyzes in the acidic tumor microenvironment to become glycyrrhetinic acid (GRA), an OXP …

24.08.2026journal-article

Chinese Medical Journal

Hepatitis B surface antigen clearance rate with pegylated interferon-α therapy in different chronic hepatitis B virus infection populations: A systematic review and meta-analysis

Chengrun Song, Yalin Yin, Jingwen Feng, Yujing Li, Min He, Yonghong Wang, Menglan Wang, Yachao Tao, Taoyou Zhou, Fang He, Jiajie Lu, Wei Jiang, Dongbo Wu, Hong Tang, Xuezhong Lei, Enqiang Chen

Abstract Background: Chronic hepatitis B virus (HBV) infection is an urgent public health issue, particularly in endemic regions of Asia and sub-Saharan Africa. Achieving hepatitis B surface antigen (HBsAg) clearance significantly reduces the risk of hepatocellular carcinoma. Pegylated interferon alpha (PegIFNα) is widely recognized as the preferred treatment. However, the efficacy of PegIFNα in different chronic HBV infection populations has not been systematically evaluated. This study aimed to assess the HBsAg c …

24.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

Noise Reduction Strategies For Optimising Speech Signal Clarity

Savita More, Jagdish Helonde, Prakash G. Burade

Noise suppression that improves speech intelligibility is critical in teleconferencing, Voice over Internet Protocol (VoIP), hearing aids, and speech recognition systems. This work has attempted an adaptive filtering technique for noise suppression to improve the performance of speech signals. In this regard, two of the most popular algorithms, namely the Recursive Least Squares (RLS) algorithm and Normalised Least Mean Squares (NLMS) algorithm, specifically for existing speech distortion enhancement by room noise, …

24.08.2026journal-article

Scientific Reports

Visual feedback using electrical impedance tomography during inhalation therapy for chronic obstructive lung disease: a pilot study

Svenja Stolz, Rosa Meyer, Torben Rixecker, Robert Bals, Philipp M. Lepper, André Becker

Abstract Airflow limitation and hyperinflation contribute to increased respiratory workload and dyspnea in COPD. Inhalation therapy plays a crucial role, but its effectiveness depends on correct technique. Electrical impedance tomography (EIT) offers real-time visualization of ventilation and may improve inhalation technique, when used as visual feedback. This study aimed to investigate the impact of feedback-guided inhalation using EIT on lung function, specifically targeting obstructive and hyperinflation paramet …

31.08.2026journal-article

International Journal “Speech Genres”

Ethical assessments as a way of forming the image of Russia in the genre of Telegram messages (the case of Ukrainian Telegram channels)

Anatoly P. Chudinov, Eduard V. Budaev, Eseniya S. Chistyakova

The article deals with the analysis of linguistic and cognitive mechanisms for implementing ethical assessment in the genre of Telegram messages. The study is based on ethical assessments in messages of Ukrainian Telegram channels when constructing the image of Russia. The corpus included channels occupying leading positions in the TGStat rating by the number of subscribers and citations in the thematic groups “Media” and “Politics”. The methodology of the study is based on the postulates of cognitive-discursive an …

24.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Low-Intensity Distortion Product Otoacoustic Emission Protocols in Infants and Young Children: Contributions of Age-Specific Ear Characteristics

Ana Paula Bruner, Uzma Shaheen Akhtar, Sumitrajit Dhar, Renata Mota Mamede Carvallo, Alessandra Spada Durante

Purpose: Despite almost complete cochlear maturity at birth, distortion product otoacoustic emission (DPOAE) levels in neonates and infants are typically higher than those measured in older children and adults, depending on the type and frequency stimulus, which suggests functional immaturity of the cochlea as well as the role of the outer and/or middle ear. This study aimed to investigate the relationship between outer and middle ear characteristics, using wideband tympanometry (WBT), and DPOAEs and to evaluate th …

24.08.2026journal-article

The Journal of Dermatology

Efficacy, Safety, and Predictive Value of Quantitative Histopathology in Picosecond Laser Therapy for Congenital Melanocytic Nevi: A Prospective Clinical Trial

Kayo Kunimoto, Chikako Kaminaka, Kyoko Muraoka, Tomoyuki Hara, Minako Tanaka, Masatoshi Jinnin, Yuki Yamamoto

ABSTRACT In this single‐arm prospective study, we evaluated the efficacy and safety of a 1064/532‐nm Nd:YAG picosecond laser for congenital melanocytic nevi (CMN) and investigated the association between clinical response and quantitative histopathologic findings. Thirteen Japanese patients with a median age of 4 years were enrolled and received up to five laser treatment sessions at 1‐ to 3‐month intervals. Clinical efficacy was primarily assessed using the Investigator Global Assessment (IGA) score at 3 months af …

24.08.2026journal-article

Surabaya Physical Medicine and Rehabilitation Journal

Activities of Daily Living Improvement among Post-Stroke Patients Receiving Cognitive Behavioral Therapy: An Observational Study

Linda Ramadhanty Pramesta, Rita Vivera Pane, Wiwik Winarningsih, Aisyah, Aufar Zimamuz Zaman Al Hajiri

Background: The prevalence of stroke is now increasing along with the increase in metabolic diseases. In addition to having an impact on mortality rates, stroke is also a burden due to the increase in morbidity rates. Post-stroke patients usually experience disabilities, which causes a decrease in their independence in carrying out daily activities (ADL). Aim: Aimed to observe the effect of cognitive behavior therapy (CBT) on ADL among post-stroke patients. Material and methods: An observational analytical cross-se …

24.08.2026journal-article

SDÜ SAĞLIK BİLİMLERİ DERGİSİ

Anxiety And Depression Level Of Patients Receiving Renal Replacement Therapy During The Covid-19 Outbreak

Atila Altuntaş, Sıddıka Ersoy, Şeniz Tutum, Hasret Demirel

Introduction: Depression and anxiety are common psychological complications in patients with end-stage renal disease (ESRD) receiving renal replacement therapy (RRT). The COVID-19 pandemic has further exacerbated the psychological distress experienced by these patients. This study aimed to investigate the anxiety and depression levels of patients receiving RRT during the COVID-19 outbreak and to identify the factors associated with these psychological outcomes.Materials and Methods: This descriptive study was condu …

24.08.2026journal-article

Biomedicines

Pathogenesis-Informed Phenotype-Guided Therapy for MASH: A Three-Axis Translational Framework Within the MASLD Spectrum

Zishu Zhao, Xiaoyang Hu

Metabolic dysfunction-associated steatohepatitis (MASH) is the progressive inflammatory and fibrotic subtype of metabolic dysfunction-associated steatotic liver disease (MASLD), and its treatment landscape is rapidly moving from nonspecific liver fat reduction towards mechanism-based drug positioning. Since 2024, resmetirom and semaglutide have received U.S. Food and Drug Administration accelerated approval for non-cirrhotic MASH with moderate-to-advanced fibrosis, while tirzepatide, survodutide, and fibroblast gro …

24.08.2026journal-article

Kemakmuran Hijau: Jurnal Ekonomi Pembangunan

Waqf-based rehabilitation of former mining land: Cash waqf linked to infrastructure fund (CWL-FRA) and phytomining models for sustainable economic growth

Biruni Ahmad Safin, Adzka Sya'bani Mas'ud, Ajrul Rais Ananda

Background: Abandoned mining lands in Indonesia face severe environmental degradation caused by heavy metal contamination, limiting their agricultural and productive potential. Rehabilitation therefore requires an approach that simultaneously addresses environmental pollution, economic recovery, and social development. This study aims to develop a cash waqf-based rehabilitation model integrating Islamic social finance with phytomining technology for sustainable post-mining land recovery. Methods: This study employe …