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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
25.08.2026journal-article

Clinical Rehabilitation

Biofeedback in Parkinson's disease: A systematic review with meta-analysis

Arielle Baumgart, Elisabeth Preston, Louise Ada, Maria Tereza M Alvarenga, Juliana FB de Mondença, Allyson Flynn

Objectives The objective was to examine whether the addition of biofeedback to practice is effective in improving lower limb activity compared with practice alone for people with Parkinson's disease. Data sources Four databases were searched for randomised trials of adults with idiopathic Parkinson's disease. Trials included biofeedback delivered concurrently during practice of sitting, standing up, standing and/or walking compared with the same amount of practice without biofeedback. Outcomes were measures of acti …

25.08.2026journal-article

International Journal of Psychosexual Therapy

202: On the Evaluation of sex acts in Shi’a Islamic Theology and Jurisprudence

Donja Hodaie

The evaluation of sexual acts is an important topic in Islamic theology, with many scholars offering their viewpoints based on their understanding of Islamic sources. Islamic religious beliefs and teachings significantly shape Muslim perspectives and attitudes toward issues related to sexual acts, sexual orientation, and identity. The belief that engaging in or abstaining from certain sexual acts is a moral disorder and forbidden in Islam is deeply ingrained in the minds of many Muslims. The fear of divine punishme …

25.08.2026journal-article

International Journal of Psychosexual Therapy

103: Disappointment, confusion and anger in ultra orthodox Jewish marriages

Judi Keshet-Orr

Within the Orthodox Jewish community, marriages are often arranged through a shidduch process. This process takes into account the wishes, hopes, and expectations of parents, including levels of religious observance and the backgrounds of the respective families. While many such marriages are successful, many are not. This paper is largely based on clinical experience and anecdotal evidence in which couples have reported feeling unheard and unseen. These experiences can lead to frustration, psychosexual mismatching …

25.08.2026journal-article

Language and Speech

Interaction of Frequency and Inflectional Status: An Approach From Discriminative Learning

Motoki Saito, Fabian Tomaschek, R. Harald Baayen

High frequency of occurrences has been associated with phonetic reduction, on one hand, and phonetic enhancement, on the other hand. This study first looks into the possibility that these opposite frequency effects are at least partially due to the different inflectional status of the items being investigated. Based on tongue position data from a spontaneous speech corpus of German, we found that stem vowels in inflected words tended to be hyper-articulated (i.e., phonetic enhancement), whereas those in non-inflect …

25.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

Developmental Transactions Between Infant Gaze and Maternal Responsiveness and Measures of Social-Emotional Competence in Toddlerhood

Cristin M. Holland, John Sideris, Barbara L. Thompson, Pat Levitt, Grace T. Baranek

Background: Infants and their caregivers reciprocally influence each other through transactions within everyday activities, facilitating further child development. Objectives: This study assessed a transactional pathway between infant gaze capacities and maternal responsiveness across development and associations with child joint engagement at 24 months and social-emotional competence at 36 to 42 months of age. Methodology: Videos of mother–child play at 2, 6, 9, 12, 18, and 24 months were used to behaviorally code …

25.08.2026journal-article

Bulletin of Rehabilitation Medicine

Natural healing factors: a systematic analysis of the evidence base and prospects for application in pediatric practice

Nina S. Prilipko, Natalia A. Mokina, Mikhail V. Nikitin, Natalia V. Machula, Anfisa M. Nikitina

INTRODUCTION. Natural healing factors (NHF) — mineral waters, therapeutic mud, climate, and saline solutions — have a centuries-long history of use in pediatrics. However, to date, there is no systematic analysis of the evidence base for the effectiveness of NHF for various childhood diseases, with a gradation of levels of evidence according to GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria. AIM. To conduct a systematic analysis of modern scientific data on the effectiveness of n …

25.08.2026journal-article

Pakistan Journal of Medical Sciences

Hepatitis-B virus reactivation during Immunosuppressive therapy: Clinical observations from a tertiary care center

Bekir Tunca, Nevin Ince, Şengül Cangür

Objectives: This study evaluated the incidence of hepatitis B virus reactivation (HBVr) in patients receiving immunosuppressive therapy and examined the association between anti-HBs titers and reactivation risk in routine clinical practice. Methods: This retrospective study was conducted at Düzce University Faculty of Medicine Hospital between 2017 and 2020. Adult patients (≥18 years) receiving immunosuppressive therapy and monitored for HBVr were included. A total of 166 patients who were either HBsAg-positive or …

25.08.2026journal-article

The Eurasian Journal of Medicine

Statistical Reporting Quality in Physical Medicine and Rehabilitation Journals: A Comparative Analysis of SCI-E and TR Indexed Publications

Tuğba Şahbaz, Gülsev Özen Yorgancıgil, Ahmet Dirican

Background: To evaluate statistical reporting quality and methodological errors in clinical research articles published in physical medicine and rehabilitation (PM&R) journals indexed in Science Citation Index Expanded (SCI-E) and Turkish National Citation Index (TR Dizin). Methods: This cross-sectional methodological study analyzed original clinical research articles published between January 2024 and January 2025 in 18 PM&R journals indexed in SCI-E and TR Dizin. Articles were evaluated using predefined criteria …

25.08.2026journal-article

Language and Speech

The Architecture of Bilingual Phonological Knowledge and Performance

John Archibald

In this paper, I propose a formal model of the representation and processing of an integrated multilingual phonological grammar. Two options are considered: (a) a merged union of features from all languages, and (b) an integrated repository which includes representational language tags on hierarchical phonological structures. I argue that the tagged model is preferred given that the merged-union proposal runs into problems with (a) ranking paradoxes, and (b) requiring extra theoretical machinery to block subsets of …

25.08.2026journal-article

International Journal of Psychosexual Therapy

206: Race, Trauma, and the Erotic: A Black Therapist’s Framework for Working with Interracial Couples

Robert Hudson

Interracial couples bring together not only different personal histories but also the cumulative weight of cultural, racial, and intergenerational narratives that shape how intimacy, desire, and erotic experience are lived and understood. These narratives influence power, safety, embodiment, and sexual expression, often outside of conscious awareness. Drawing on clinical experience as a Black male psychosexual and relationship therapist, this presentation examines how racialized trauma is stored in the body and how …

25.08.2026journal-article

The Journal of the International Association of Adventure and Nature Based Therapies

A Novel Danish Adventure Therapy Intervention

Ida Lousen, Søren Andkjær

Declining mental well-being among adolescents and young adults is a growing public health challenge in Denmark and across the Western world. Nature-based interventions, including adventure therapy, have shown promising results in improving mental well-being outcomes, yet evidence remains limited regarding effective mechanisms, contextual factors, and implementation strategies. This pilot study introduces a mixed methods design to evaluate a complex intervention targeting vulnerable adolescents in Southern Funen, De …

25.08.2026journal-article

Bulletin of Rehabilitation Medicine

Dry needling versus instrument assisted soft tissue mobilization with cervical mobilization for upper trapezius myofascial pain syndrome: a quasi-experimental study

Rahmat Nugraha, Latifa I. Nurhalim, Sudaryanto Sudaryanto, Hasbiah Hasbiah, Tiar Erawan

INTRODUCTION. Myofascial Pain Syndrome (MPS) Upper is a chronic condition caused by the activation of trigger points in muscle fibers that cause neck pain and discomfort. Prolonged pain and tightness resulting in limitation of lateral flexion and cervical rotation. AIM. To determine the difference effect between Dry needling and Instrument Assisted Soft Tissue Mobilization (IASTM) on the application of Unilateral down glide on reducing pain and increasing cervical Range of Motion (ROM) in the condition of upper tra …

25.08.2026journal-article

Scientific Reports

The impact of HIV and antiretroviral therapy on cervical cancer burden in Zambia: a modelling study

John Andoh, Herbert Kapesa, Susan Citonje Msadabwe, Albert Manasyan, Paul Kamfwa, Watson Zulu, Cliff Kerr, Matthias Egger, Eliane Rohner, Robyn Stuart, Cari van Schalkwyk

Abstract Cervical cancer is the leading cause of cancer death among women in Zambia, where widespread HIV infection elevates cervical cancer risk. However, HIV’s contribution to Zambia’s cervical cancer burden and the extent to which antiretroviral therapy (ART) has mitigated this burden, remain poorly quantified. We adapted HPVsim, an existing open-source mathematical model simulating human papillomavirus (HPV) and cervical cancer natural history, to capture the dual burden of cervical cancer and HIV in Zambian wo …

25.08.2026journal-article

Journal of Nephrology

Thyroid tests in kidney failure: diagnostic stewardship before levothyroxine therapy

Yoshitaka Furuto, Daiki Yoshino, Akio Namikawa, Dai Sato, Yuko Shibuya

Abstract Advanced chronic kidney disease and kidney failure frequently produce thyroid-test patterns that resemble primary hypothyroidism. The clinical challenge is not to dismiss abnormal results, but to distinguish persistent, treatment-requiring thyroid failure from uraemic, non-thyroidal, volume-related, medication-related, and analytical mimics before committing a vulnerable patient to long-term levothyroxine. This structured, evidence-informed narrative review critically appraises epidemiology, dialysis-speci …

25.08.2026journal-article

Advanced NanoBiomed Research

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

Ao Shen, Liwen Zhang, Helen Forgham, Jiayuan Zhu, Xumin Huang, Changkui Fu, Ibrahim Javed, Thomas P. Davis, Ruirui Qiao

Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by the deposition of amyloid‐beta (Aβ) plaques in the brain. Early diagnosis and effective targeted therapies remain critical challenges in managing AD. Herein, we present the design and development of novel functional polymer‐engineered magnetic nanoparticles for Aβ‐targeted diagnosis and therapeutic intervention. These nanoparticles feature a 3 nm iron oxide nanoparticle core for magnetic resonance imaging enhancement, as well as a functi …

25.08.2026journal-article

Journal of Speech, Language, and Hearing Research

From Underrepresentation to Inclusion: Women Who Stutter in Research and Practice

Ran An, Charn Nang, Ai Leen Choo, Ineke Samson

Purpose: Women who stutter have historically received limited analytic attention in stuttering research and clinical practice. Although the higher male-to-female persistence ratio partly shapes sample composition, repeated reliance on male-majority samples has also contributed to a sex-skewed evidence base, limiting insight into women's experiences and clinical needs. Using a biopsychosocial framework, this article identifies key domains for inquiry and proposes a research, clinical, and educational agenda to addre …

25.08.2026journal-article

International Journal of Psychosexual Therapy

101: When Western Sex Therapy Crosses Borders: Clinical and Cultural Lessons from Training Romanian Psychosexual Therapists

Vanessa Snyder, Anda Mogos

This paper examines the clinical, cultural, and ethical complexities encountered while training psychosexual therapists in Romania through a multi-year international collaboration. Western sex therapy models often presume individual autonomy, open sexual expression, and value-neutral clinical frameworks—assumptions that can conflict with collectivist social norms, post-communist historical narratives, and deeply rooted religious worldviews. Drawing from sustained clinical training, supervision, and dialogue with Ro …

25.08.2026journal-article

International Journal of Psychosexual Therapy

306: Sex Therapy with Neuro-spicy Couples

Lena Fenton

Clinicians working in sex and relationship-focused (SF) therapy must be thoroughly trained in understanding how sensory features impact sensuality, sexuality, and eroticism for autistic individuals and couples. Sensory sensitivities are highly prevalent in autistic populations and can significantly influence experiences of intimacy, connection and sexual functioning (Minshew & Hobson, 2008). These sensitivities may manifest as heightened or diminished responses to touch, sound, light, or other sensory inputs, which …

25.08.2026journal-article

Drug Metabolism and Personalized Therapy

Assessment of the impact of valproic acid co-administration on clozapine plasma concentrations in Tunisian patients

Syrine Ben Hammamia, Safa Souissi, Mariem Bettoumia, Mouna Ben Sassi, Khouloud Ferchichi, Mouna Daldoul, Hanene El Jebari, Mohamed Zouari, Issam Salouage, Rim Charfi, Riadh Daghfous, Emna Gaies, Sameh Trabelsi

Abstract Objectives Reports on drug-drug interactions between Valproic Acid (VPA) and Clozapine (CLZ) are very inconsistent. Previous reports demonstrate that VPA may exhibit either inhibitory or inductive effects or have no effect on CLZ pharmacokinetics. The aim of this study was to investigate the impact of VPA on plasma CLZ concentrations in a series of Tunisian patients. Methods This retrospective study was conducted from 2010 to 2025 at the Clinical Pharmacology Department of the Tunisian National Pharmacovig …

25.08.2026journal-article

Frontiers in Cardiovascular Medicine

Novel echocardiographic tools for predicting a good response to cardiac resynchronization therapy: a narrative review

Beata Uziębło-Życzkowska, Despina-Manuela Toader, Magdalena Potapowicz-Krysztofiak

Despite significant progress in new echocardiographic techniques, the role of echocardiography in qualifying patients for cardiac resynchronisation therapy (CRT) remains limited solely to the assessment of left ventricular ejection fraction (LVEF). This review aims to present the current knowledge on new echocardiographic methods that may be useful in predicting the response to resynchronization. Recent advances in speckle-tracking echocardiography (STE) have introduced several promising parameters. Measures such a …

25.08.2026journal-article

Language, Speech, and Hearing Services in Schools

Estimated Prevalence of Developmental Language Disorder Risk in West Virginia Schools

Megan Israelsen-Augenstein, Michelle W. Moore, Tracy Toman, Allison Rosborough

Purpose: Developmental language disorder (DLD) is linked to long-term academic and social difficulties. Despite these lasting impacts, state-level prevalence estimates are limited. This study estimated prevalence among early-elementary students in West Virginia who may be at risk for DLD and examined variation by grade, locale, and assessment instrument. Method: A cross-sectional screening battery was administered to 252 students in Grades 1–2 across six Title I schools. Children with Kaufman Brief Intelligence Tes …

25.08.2026journal-article

International Journal of Hematology

Persistent parkinsonism with dopaminergic denervation following axicabtagene ciloleucel therapy for diffuse large B cell lymphoma: a case report

Wataru Kinoshita, Michiaki Sato, Yuya Kurihara, Arika Shimura, Akira Honda, Yosuke Masamoto, Ayaka Seki, Meiko Maeda, Wataru Satake, Mineo Kurokawa

Abstract While immune effector cell-associated neurotoxicity syndrome (ICANS) remains one of the major adverse events in CD19-targeted CAR-T cell therapy, neurodegenerative-like movement disorders are characteristically associated with BCMA-targeted therapies, not CD19. We report a distinct case of persistent parkinsonism that became evident during recurrent neurological deterioration accompanied by a decline in ICE score in a patient treated with axicabtagene ciloleucel for relapsed diffuse large B cell lymphoma. …

25.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

OCCUPATIONAL FATIGUE IN HYBRID AND REMOTE WORK REGIMES: IMPLICATIONS FOR MENTAL HEALTH AND WORK SAFETY IN THE AGRICULTURAL SECTOR

Giovane Moreno, Josefa Moreno, Danielly Veloso Blanck, Thompson Ricardo Weiser Meier, Neivair Sponchiado Pastore, José Barbosa Duarte Júnior

Recent digital transformations have significantly changed work organization, expanding the adoption of remote and hybrid work arrangements across different sectors. Although these modalities provide benefits such as flexibility, autonomy, and reduced commuting, they have also introduced new challenges related to mental health, ergonomics, and occupational safety. In the agricultural sector, these factors may be intensified by the combination of field activities, travel, technical responsibilities, and digital deman …

25.08.2026journal-article

Statistics in Medicine

Dynamic Predictions and Predictimands for Salvage Therapy in Recurrent Prostate Cancer Using Joint Models

Lukas Owens, Dimitris Rizopoulos, Jonathan Fainberg, Sigrid Carlsson, Nicole Liso, Sean McBride, Vincent Laudone, Ruth Etzioni, Jeremy M. G. Taylor

ABSTRACT Prostate cancer patients with biochemical recurrence (BCR) face a decision of whether to start salvage therapy (ST), which may reduce the probability of metastatic progression at the cost of side effects. To inform the decision to start ST at or after BCR, models that make counterfactual predictions incorporating treatment are highly desirable. However, estimation of such models using observational data requires care due to time‐varying confounding by the longitudinal biomarker prostate‐specific antigen (P …