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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
25.08.2026journal-article

Medical Care Research and Review

Mental Health Therapy Utilization Among Transgender Medicare Beneficiaries, From 2011 to 2019

Bryce J. Stanley, Gray Babbs, Jaclyn M.W. Hughto, David Meyers

We examined outpatient mental health counseling use among transgender and gender-diverse (TGD) and cisgender Medicare beneficiaries from 2011 to 2019 using a cross-sectional analysis of Medicare claims data. TGD individuals were identified using a validated claims-based algorithm. The sample included 39,215 TGD beneficiaries and a 20% random sample of cisgender beneficiaries ( N = 17,375,985). Similar to prior studies, TGD beneficiaries were more likely to use outpatient mental health counseling than cisgender bene …

25.08.2026journal-article

Recent Patents on Anti-Cancer Drug Discovery

Multi-target Drug Discovery for Cancer Therapy: A Contemporary Review

Thirumalaikumaran Rathinam, S. Pradeep Kumar Reddy, Yella Sirisha, Voleti Vijaya Kumar, Byran Gowramma, Dipen Purohit, Kaviarasan Lakshmanan

Introduction: Cancer remains one of the leading causes of mortality worldwide, with conventional therapies often limited by systemic toxicity, therapeutic resistance, and tumor heterogeneity. Multi-target drug discovery has emerged as a contemporary strategy to overcome these challenges, particularly through multi-kinase inhibitors and bispecific antibodies that simultaneously modulate multiple oncogenic pathways. Methods: This review integrates evidence from preclinical investigations, pivotal clinical trials, reg …

25.08.2026journal-article

Bulletin of Rehabilitation Medicine

Balneotherapy and Persian Medicine: a narrative comparative review of concepts, mechanisms, and therapeutic applications

Amir M. Jaladat, Ghazaleh Heydarirad, Ali Tavakoli, Larisa A. Marchenkova, Mehdi Pasalar

INTRODUCTION. Balneotherapy — defined as the therapeutic use of mineral-rich water, thermal baths, mud, and gases — has been practiced across cultures for centuries. Persian Medicine (PM), a holistic traditional medical system dating back more than a millennium, also incorporates extensive water-based therapies, medicinal clays, and thermal practices. AIM. To compare balneotherapy with related therapeutic modalities described in classical PM texts, highlighting historical foundations, mechanisms of action, clinical …

25.08.2026journal-article

Clinical Case Studies

A Clinical Case Study of Cognitive Behavior Therapy for Young Adult Cancer Survivors’ Psychological Distress: Utilizing the Generic Cognitive Model

Anao Zhang, Meiyan Chen, Vincent Luong

Adolescents and young adults (AYAs) diagnosed with cancer often experience psychological distress that reflects the interaction of medical uncertainty, developmental disruption, and pre-existing cognitive and coping patterns. This clinical case study illustrates the use of cognitive behavior therapy (CBT), informed by the Generic Cognitive Model, with a 23-year-old young adult survivor of Hodgkin lymphoma experiencing anxiety, depressive symptoms, fear of cancer recurrence, avoidance, and difficulty re-engaging wit …

25.08.2026journal-article

American Journal of Advanced Medical and Surgical Sciences

Examining the Relationship between Work-Life Balance, Occupational Stress, Job Satisfaction, and Organizational Commitment among Professionals in Public and Private Sectors

Research Author

The present study examines the relationship between work-life balance, occupational stress, job satisfaction, and organizational commitment among professionals working in public and private sectors. Work-life balance has become an important concern in modern organizations because employees are required to manage professional responsibilities along with family, personal, and social roles. Poor work-life balance may increase occupational stress, reduce job satisfaction, and weaken commitment toward the organization. …

25.08.2026journal-article

Revista ft

Perda funcional da marcha e do equilíbrio em pacientes pós-Acidente Vascular Cerebral: implicações para a Fisioterapia

Ádila Pinheiro Falcão da Costa, Raí da Silva Lopes

Stroke is one of the leading causes of death and disability in adults, and gait and balance impairments are among its most frequent and limiting sequelae. This study aimed to analyze the main functional gait and balance impairments in post-stroke patients reported in the scientific literature, highlighting their repercussions on mobility, functional independence, fall risk, and physical therapy practice. This narrative literature review used a structured search of PubMed/MEDLINE, PEDro, SciELO, Cochrane Library (vi …

25.08.2026journal-article

Research, Society and Development

Recuperação de púrpura trombocitopênica trombótica em paciente com HIV antes do início de terapia antirretroviral: Um relato de caso

Luan Filipe Viana Saldanha, Luciana Reis de Almeida Braga, João Victor Cinício Cavalcanti, Marçal Durval Siqueira Paiva Júnior

A púrpura trombocitopênica trombótica imune (PTTi) é uma microangiopatia trombótica potencialmente fatal decorrente da deficiência grave de ADAMTS13 mediada por autoanticorpos. Na infecção pelo vírus da imunodeficiência humana (HIV), a distinção entre PTTi e microangiopatia trombótica secundária ao próprio vírus é desafiadora e tem implicações terapêuticas diretas. O objetivo deste trabalho foi relatar e analisar um caso de púrpura trombocitopênica trombótica em paciente com infecção pelo HIV, enfatizando a respost …

25.08.2026journal-article

Healthcare

Enhancing Empathy and Emotional Awareness in Intrapartum Care Through Role-Reversal Simulation: A Mixed-Methods Study with Midwifery Students

Yeliz Yıldırım Varışoğlu, Selinay Aktaş Demir, İffet Güler Kaya

Background/Objectives: This study evaluated the effects of a role-reversal simulation-based educational intervention on midwifery students’ emotional availability and responsiveness in intrapartum care and explored their experiences of the simulation through qualitative inquiry. Methods: A mixed-methods quasi-experimental one-group pretest–post-test design was used. Forty-nine midwifery students participated in a simulation in which they alternately assumed the roles of a labouring woman and a midwife. Qualitative …

25.08.2026journal-article

International Journal of Psychosexual Therapy

401: Shadow, Symbol, and Sexuality: Integrating Sex Therapy and Art Therapy Through Depth Psychology

Michelle Dean

This didactic, experiential, and interpersonal workshop introduces an emerging, integrative approach that unites sex therapy and art therapy through a depth psychology framework, offering clinicians innovative ways to address the symbolic, somatic, and relational dimensions of human sexuality. While sex therapy traditionally emphasizes cognitive and behavioral interventions, and art therapy centers on nonverbal expression and emotional processing, their combined application remains vastly underexplored. Grounded in …

25.08.2026journal-article

International Journal of Molecular Sciences

Safety and Efficacy of Mesenchymal Stem Cell Therapy in Aging Frailty: A Systematic Review

Eleni Poutouri, Maria Sotiropoulou, Michael Potoupnis, Georgios Koliakos, Evanthia Kassi, Symeon Tournis, Panagiotis Anagnostis

Aging frailty is a multifactorial geriatric syndrome characterized by reduced physiological reserve across multiple interrelated systems, leading to increased vulnerability to adverse health outcomes. Mesenchymal stem cells (MSCs) have emerged as a potential therapeutic intervention due to their immunomodulatory and regenerative properties. This systematic review aimed to evaluate the available clinical evidence regarding the safety and efficacy of MSC administration in individuals with aging frailty. A systematic …

25.08.2026journal-article

Economía Sociedad y Territorio

La dimensión espacial de la estructura social en Argentina: una regionalización socio-ocupacional

María Clara Fernández Melián, Mariana Marcos

Este artículo estudia la dimensión espacial de la estructura social argentina desde el campo de la sociología y la articula con la geografía crítica y la teoría de la heterogeneidad estructural. Con una estrategia cuantitativa inductiva a escala departamental y un análisis de conglomerados, se construyó una regionalización socio-ocupacional que no exige contigüidad; se arribó a seis regiones con perfiles diferenciados (la cartografía resultante aporta insumos para políticas territorialmente sensibles); y se discuti …

25.08.2026journal-article

Scientia Generalis

O IMPACTO DA INTERVENÇÃO FISIOTERAPÊUTICA NA REABILITAÇÃO DE CRIANÇAS COM ATRASO NO DESENVOLVIMENTO MOTOR: Uma análise abrangente

Vanessa Camargos Rodrigues, Raphael Cezar Carvalho Maritns, Fredston Gonçalves Coimbra, Fernando Leonardo Diniz Souza

O desenvolvimento motor infantil é um processo complexo, e algumas crianças enfrentam desafios significativos, como atrasos no desenvolvimento motor, que podem resultar de fatores genéticos ou neurológicos. A intervenção fisioterapêutica desempenha um papel crucial na reabilitação, focando não apenas na correção das deficiências motoras, mas também na promoção do desenvolvimento global da criança. A fisioterapia pediátrica envolve uma abordagem personalizada e multidisciplinar, colaborando com terapeutas ocupaciona …

25.08.2026journal-article

Psychonomic Bulletin & Review

Back in time: Reversed speech as a window into cognitive language processing—A systematic review

Mathias Scharinger

Abstract The speech signal unfolds in time. This has repercussions for speech production and processing. For production, processing units are assembled in a language-specific order, while in perception, the acoustic signal is segmented into specific, temporally ordered processing units. Specific insights into the forward processing of speech and its assumed mechanisms can be gained from reversed speech. Reversed speech can be either the production of speech in reverse order by skilled speakers (subjectively reverse …

25.08.2026journal-article

Cardiovascular Drugs and Therapy

Spontaneous ST-Segment Elevation in Right Precordial Leads Following Cardiac Arrest: Literature Review and Management Proposal for Ruling out Brugada Syndrome

Pierangelo Calvelli, Vincenzo Racco, Antonio Curcio

Abstract Purpose Electrocardiogram (ECG) evaluation after return of spontaneous circulation (ROSC) represents a crucial step in the diagnostic work-up of sudden cardiac death (SCD) survivors. Among ECG patterns, the Brugada syndrome (BrS) type 1 morphology, characterized by coved ST-segment elevation in right precordial leads, requires a prompt differential diagnosis, as it may reflect either a true BrS, or a BrS phenocopy, or yet an acquired sodium channel dysfunction. Methods This focused narrative review provide …

25.08.2026journal-article

Journal of Endovascular Therapy

Risk Prediction Models for Unplanned 30-Day Readmission After Discharge of Patients After Undergoing Coronary Revascularization: A Systematic Review and Meta-Analysis

Shichun Wang, Jing Li, Hong Zhang, Qing Zhang, Tongtong Wang, Zhijuan Xie, Jing Yang

Background: Unplanned 30-day readmission is a critical quality indicator in clinical health care. Although the number of risk prediction models related to this research is increasing, uncertainties remain regarding their methodological rigor and clinical practical value. Objective: This study aims to systematically evaluate risk prediction models for unplanned 30-day readmission following coronary revascularization, providing evidence to inform clinical practice and guide future model development. Methods: We ident …

25.08.2026journal-article

Frontiers in Medicine

Changing epidemiology of non-occupational acute carbon monoxide poisoning and the increasing share of older adults during the clean heating transition: a 10-year emergency department study in rural Tianjin, China

Wei Kang, Yanqiu Du, Miao Zhao, Jisheng Yang, Jian Liang, Xin Wang, Xianjia Ning, Guohua Zhao

Background and Objective Non-occupational Acute Carbon Monoxide Poisoning (ACOP) remains a preventable emergency condition in northern rural China, where winter heating and indoor combustion have historically been important exposure sources. In rural Tianjin, the clean heating transition period was accompanied by a substantial decline in the overall incidence of non-occupational ACOP, while the residual burden shifted toward older adults and lifestyle-related exposure sources. However, whether this transition has c …

25.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Plyometric-jump training with versus without unstable load to improve physical fitness in trained young volleyball players: a randomized controlled trial

Parsa Soltani, Rodrigo Ramirez-Campillo, Mohammad Fashi, Atle H. Saeterbakken, Khosrow Ebrahim, Jerry L. Mayhew, Olaf Prieske

Abstract Background Plyometric-jump training (PJT) has been recommended as an effective resistance training modality for enhancing vertical jump and lower limb muscle power in young athletes. While unstable surfaces are popular means to address progression and specificity, an alternative approach for applying instability during jumping is the inclusion of unstable loads. The purpose of this study was to compare the effects of unstable load PJT (UL-PJT) to PJT without unstable load (S-PJT) on physical fitness (i.e. …

25.08.2026journal-article

Arthritis Care & Research

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman

Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis. Patients were considered in the early treatment group if they had started on biologic therapy within two years of PsA diagnosis; otherwise, they were considered in the delayed treatment group. The primary …

25.08.2026journal-article

ACS Applied Nano Materials

Aptamer-Functionalized ZIF-8 Nanoscale Platform Codelivering Sorafenib and GPX4 siRNA for Targeted Osteosarcoma Therapy

Kai Liu, Hongliang Shen, Jietao Li, Yu Feng, Chang Zhou, Anlong Jiang

Abstract Osteosarcoma remains a highly aggressive primary bone malignancy, and its clinical treatment is frequently limited by chemoresistance, systemic toxicity, and insufficient tumor-specific drug accumulation. To address these challenges, we developed an OS-7.9 aptamer-functionalized ZIF-8 nanoscale platform for the targeted codelivery of sorafenib (SFN) and GPX4 siRNA, designated O-SR-ZIF-8, with the intended application of ferroptosis-based osteosarcoma therapy. The resulting nanoparticles exhibited a uniform …

25.08.2026journal-article

Journal of Patient-Reported Outcomes

Predictors for non-response to PROMs across three areas of inpatient rehabilitation – a nationwide cross-sectional study in Switzerland

Frederike Basedow, Gavin Brupbacher, Anke Scheel-Sailer, Thomas Sigrist, Jan Vontobel, Manuela Marquardt, Marie Utsch, Gaia Garuffi, Stephan Tobler, Anika Zembic

Abstract Background Patient-reported outcome measures (PROMs) are valuable tools to integrate the patient perspective and improve quality of rehabilitation services. However, there is a risk of non-response bias. Identifying characteristics associated with non-response is important to reduce barriers to PROM completion and to ensure quality care for all patients undergoing rehabilitation. Methodology In this cross-sectional observational study, we used routine data from the Swiss national quality assurance program …

25.08.2026journal-article

Vaccines

Hepatitis B Immunization Among Healthcare Students: A Narrative Review of Occupational Risk, Seroprotection, and Immunization Management

Lorenzo Ippoliti, Viola Giovinazzo, Luca Coppeta, Giuseppe Bizzarro, Cristiana Ferrari, Andrea Mazza, Agostino Paolino, Silvio Pallone, Matteo Pasanisi, Claudia Salvi, Greta Verno, Andrea Vischetti, Andrea Magrini

Background/Objectives: Healthcare students face an occupational risk of hepatitis B virus (HBV) exposure during clinical training, often many years after receiving their primary vaccination series in infancy or childhood. Progressive waning of anti-hepatitis B surface (anti-HBs) antibody titres, heterogeneous vaccination histories in international student cohorts, high rates of underreported needlestick injuries, and variable occupational health protocols across institutions raise important questions about the adeq …

25.08.2026journal-article

Journal of Umm Al-Qura University for Medical Science

Bridging the AI gap in nursing and midwifery education: A cross-sectional analysis of predictors of use and knowledge in Ghana

Beatrice Bella Johnson, James Osei Yeboah, Ellen Eyi Klutsey, Irene Agbo, Sylvester Yao Lokpo, Richard Vikpebah Duneeh, Livingston Asem, Donkor Princess Pearl Gyamfua, Precious Kwablah Kwadzokpui, Jaiyeola Kofi Bohli, Kenneth Ablordey

Abstract Background Artificial Intelligence (AI) offers transformative potential for healthcare education, yet its adoption among key frontline cadres in low-resource settings remains poorly understood. This study is the first to investigate the predictors of AI usage and knowledge among nursing and midwifery students in Ghana. Methods An analytical cross-sectional study was conducted with 676 students from the University of Health and Allied Sciences, recruited via convenience sampling. A validated questionnaire a …

25.08.2026journal-article

Drug Metabolism and Personalized Therapy

Association of HTR2A (rs6313) gene polymorphism with autism spectrum disorder in Jordanian children: a case-control study

Wiam Khalil, Elaf Adel Al-Dalabeeh, Malek Zihlif

Abstract Objectives Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a significant genetic component, often linked to disruptions in the serotonergic system. The HTR2A gene, specifically the rs6313 (102T>C) polymorphism, is a primary candidate for investigating ASD susceptibility. The aim of this study is to investigate the association of rs6313 polymorphism with susceptibility to ASD in the Jordanian population. Methods In this case-control study, 99 Jordanian children with ASD and 109 …

25.08.2026journal-article

Clinical Rehabilitation

Biofeedback in Parkinson's disease: A systematic review with meta-analysis

Arielle Baumgart, Elisabeth Preston, Louise Ada, Maria Tereza M Alvarenga, Juliana FB de Mondença, Allyson Flynn

Objectives The objective was to examine whether the addition of biofeedback to practice is effective in improving lower limb activity compared with practice alone for people with Parkinson's disease. Data sources Four databases were searched for randomised trials of adults with idiopathic Parkinson's disease. Trials included biofeedback delivered concurrently during practice of sitting, standing up, standing and/or walking compared with the same amount of practice without biofeedback. Outcomes were measures of acti …