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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
18.08.2026journal-article

Australasian Psychiatry

Benzodiazepine prescribing at discharge from adult and older persons psychiatric inpatient units: A systematic review and meta-analysis

Justin McMahon, John McMaster, David Maletsky, Hesitha Abeysundera

Objective Psychiatric inpatient discharge is a prescribing transition at which benzodiazepines initiated for short-term symptom control may unintentionally continue beyond discharge. Existing guidance is limited for prescribing decisions. We aimed to estimate benzodiazepine discharge prevalence from adult and older persons psychiatric inpatient units and examine between-study heterogeneity. Methods We searched five databases from inception to 31 December 2022, updated the search on 27 November 2025 (PROSPERO: CRD42 …

18.08.2026journal-article

Journal of Applied Gerontology

Impact of Project ECHO on Primary Care Providers’ Knowledge, Confidence, and Skills in Geriatric and Dementia Care: A Scoping Review

Dominic Roby, Kallol Kumar Bhattacharyya, Ashish Joshi, Berneet Kaur, Kristina Wick, Anne Gifford, James Eaton, Daniel Ibarra-Scurr, Katherine Gifford, Raymond R. Romano

Background The shortage of geriatric specialists in the United States has increased reliance on primary care providers to diagnose and manage dementia, yet many lack adequate training in geriatric care. Objectives To examine how dementia and geriatric-focused Extension for Community Healthcare Outcomes (ECHO) programs influence provider knowledge, confidence, and clinical skills. Methods A scoping review was conducted using PubMed, Google Scholar, and PsycINFO to identify studies published between 2015 and 2025. El …

18.08.2026journal-article

Journal of Applied Gerontology

Caregiver- and Care Recipient–Related Factors Linked to Pain in Family Caregivers of Persons Living with Dementia

Mona Mohammadifirouzeh, Kyeung Mi Oh, Mary-Lynn Brecht, Raeanne C. Moore, Jennifer L. Martin, Brent T. Mausbach, Yeonsu Song

Background Family caregivers of persons living with dementia (PLWD) often experience significant psychological, financial, and social stress, increasing their risk for both mental and physical health problems. Objective This study examined factors associated with caregivers’ perceived pain in the context of dementia care. Methods This was cross-sectional study using baseline data from a dyadic clinical trial evaluating a behavioral sleep intervention for PLWD and their family caregivers. A total of 148 caregivers w …

18.08.2026journal-article

PLOS One

Rate of nicotine metabolism on risk of myocardial infarction among people with HIV who smoke cigarettes

Derartu Ahmed, Warren B. Bilker, Xiaoyan Han, Rachel F. Tyndale, Jessica Merlin, Stephen E. Kimmel, Jeffrey Martin, Michael Plankey, Katerina Christopoulos, Leila S. Hojat, Laura Bamford, Sonia Napravnik, Robert Schnoll, Rebecca Ashare, Robert Gross

Background The prevalence of cigarette use in people with HIV (PWH) is 2–3 times higher than the general population. Cigarette use increases risk of myocardial infarction (MI). Faster nicotine metabolism, quantified by the nicotine metabolite ratio (NMR) is associated with greater risk for nicotine dependence and lung cancer, but its association with MI is unknown. Methods We conducted a nested case-control study within the Center for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort. Cases were P …

18.08.2026journal-article

Frontiers in Digital Health

Social Media engagement and perceived social isolation among older adults in a changing digital environment: evidence from HINTS 2022–2024

Jingjing Gao

Background The rapid expansion of social media and emerging artificial intelligence (AI)-mediated digital environments has transformed how older adults communicate, access information, and engage with online communities. Social media platforms may provide opportunities for social connectedness and emotional support, particularly among older adults who face mobility limitations, retirement-related social changes, or reduced in-person interactions. At the same time, increased reliance on digital environments may also …

18.08.2026journal-article

Frontiers in Psychiatry

Perceived temporal reorganization during psychiatric hospitalization among people with schizophrenia: a qualitative interview study

Yujuan Qin, Qin Mao, Hualei Li, Faqiang Zhang, Suhong Wang, Dongyang Wang, Jianying Wang

Background Schizophrenia involves not only disturbances in thought, perception, and self-experience, but also disruptions in subjective temporality. During psychiatric hospitalization, recovery experiences may involve not only symptom stabilization but also patients’ efforts to make sense of continuity between past, present, and future. This study explored how inpatients with schizophrenia described their time perspective during hospitalization. Methods This qualitative interview study recruited 15 clinically stabl …

18.08.2026journal-article

Smart Cities

Data-Driven Child-Friendly Street Renewal for Health Equity in Older Urban Districts: Latent Activity–Health Profiles in Xi’an, China

Zhanhao Zhang, Xin Dong, Weijie Hou, Sitong Liu

Data-driven urban governance increasingly seeks to incorporate the needs of different population groups, yet child-sensitive evidence for public street-space renewal remains limited in older urban districts. Most studies still evaluate environmental conditions through population averages, with insufficient attention to heterogeneous child groups that may require differentiated planning responses. Based on an analytic sample of 314 children retained from 343 usable questionnaire responses collected from children age …

18.08.2026journal-article

Journal of Sleep Research

Risk of Hypertension and Mortality Among People With Narcolepsy or Idiopathic Hypersomnia: A Retrospective Cohort Analysis of the Danish National Patient Registry

Poul Jørgen Jennum, Michael Ibsen, Sam Mettam, Sarah C. Markt, Douglas S. Fuller, Jessica K. Alexander, Rikke Ibsen, Jakob Kjellberg, Caroleen Drachenberg

ABSTRACT To assess the prevalence of hypertension, risk of developing hypertension, and risk of mortality among individuals with narcolepsy or idiopathic hypersomnia in Denmark, we performed a retrospective, nationwide, cohort analysis of the Danish National Patient Registry (DNPR). Adults (aged ≥ 18 years) diagnosed with narcolepsy or idiopathic hypersomnia between 1 January 1998 and 31 December 2020 were matched 1:4 with non‐narcolepsy/non‐idiopathic hypersomnia controls based on key demographics (age, sex, marit …

18.08.2026journal-article

Frontiers in Nutrition

Skeletal muscle mitochondrial–methylation–neurotransmitter crosstalk: a novel synergistic model of betaine, tyrosine, and Cordyceps for exercise performance in older adults, individuals with metabolic disorders, and healthy populations

Chunhong Xu, Weilu Cai, Jing Li, Ying Ma

Athletic performance and exercise adaptation are influenced by intricately coordinated interactions among mitochondrial bioenergetics, methylation-dependent metabolic pathways, and the regulation of central neurotransmitters. The potential of Cordyceps-based supplementation to enhance mitochondrial ATP production, optimize oxygen utilization, and improve fatigue resistance has been extensively studied. Nevertheless, the exploration of its integration with complementary metabolic modulators remains inadequately addr …

18.08.2026journal-article

JMIR Aging

Measuring Implicit Attitudes Toward Digital Health Technologies in Older Adults Using an Influence-Aware Affect Misattribution Procedure: Development and Feasibility Study

Anna Vinnikova, Jinyue Zhan, Kailing Jin, Xianfeng Ding, Wei Sang, Weina Xu, Qian Yang

Abstract Background Older adults often express positive attitudes toward digital health technologies in surveys, yet adoption remains low. Self-report measures may not capture automatic affective reactions such as anxiety or distrust. Implicit paradigms such as the affect misattribution procedure (AMP) can reveal these automatic attitudes, but parameters optimized for younger adults may not be suitable for older adults because of age-related slowing and changes in visual processing. Objective This study aimed to ad …

18.08.2026journal-article

Journal of National Institute of Neurosciences Bangladesh

Evaluation of Post Stroke Dementia in Different Types of Stroke Patients

Imran Sarker, AKM Anwar Ullah, Abdul Kader Shaikh, Afzal Momin, MS Jahirul Hoque Chowdhury, Mohammad Enayet Hussain, Mohammad Kafil Uddin, Nayeem Anwar, Dewan Mushfiqur Rahman, Niloy Ranjan Roy

Background: Post-stroke dementia is defined as any dementia occurring after stroke, and includes vascular dementia (VaD), degenerative dementia (mostly Alzheimer’s disease, AD) and mixed dementia (coexistence of vascular and degenerative changes). We aimed to evaluate the patients of stroke developing this vascular cognitive impairment event by this study. Objective: The purpose of the present study was to evaluate post stroke dementia (PSD) after different types of strokes and to find out the determinants of demen …

18.08.2026journal-article

SLEEP

An actigraphy-based algorithm to assess daytime napping in people with narcolepsy type 1

Raul Torres, Rahul Ghosal, Melissa Naylor, Simerpal K Gill, Yelena Pyatkevich, Sarah L Bermingham, Derek L Buhl, Brian Tracey, Marta Karas, Francesco Onorati, Vadim Zipunnikov, Dmitri Volfson

Abstract Study Objectives Excessive daytime sleepiness is a defining symptom of narcolepsy, affecting daily functioning and quality of life. We developed and evaluated an actigraphy-based nap detection algorithm to objectively estimate daytime naps, a key manifestation of excessive daytime sleepiness. Methods The nap detection algorithm was developed using data from the Multi-Ethnic Study of Atherosclerosis. This dataset included manually annotated naps from 2237 participants with 7 days of wrist-worn actigraphy. T …

18.08.2026journal-article

Frontiers in Forests and Global Change

Navigating the dual nature of wildfire in the Anthropocene: a framework for assessing impacts on nature’s contributions to people and pathways to adaptive management

Lacour M. Ayompe, Micah Elias

Wildfires historically shaped and sustained global biomes, but climate change, strict fire exclusion policies, and rapid expansion into the wildland–urban interface have fueled an era of unprecedented, high-severity “megafires.” This review synthesizes current literature on the dual nature of wildland fires, categorizing their impacts on material, non-material, and regulating Nature’s Contributions to People (NCP) using the IPBES framework. Grounded in case studies from regions experiencing acute megafires includin …

18.08.2026journal-article

Frontiers in Medicine

The relationship between alexithymia, meaning in life, and quality of life in older breast cancer patients: a cross-sectional study based on variable-centered and person-centered perspectives

Qi Lv, Yawen Deng

Background Alexithymia, characterized by difficulties in identifying and expressing emotions, has been linked to diminished quality of life in older breast cancer patients, a vulnerable population facing multifaceted psychosocial challenges. While prior research has explored these associations, investigations have predominantly adopted a variable-centered approach, overlooking the potential statistical mediating role of meaning in life. Moreover, no studies have examined the heterogeneity of alexithymia and meaning …

18.08.2026journal-article

Diabetic Medicine

The effect of telemonitoring on quality of life in people with insulin‐treated type 2 diabetes: A secondary analysis of a randomised controlled trial

Rúni Knoph, Jannie Toft Damsgaard Nørlev, Thomas Kronborg, Peter Vestergaard, Morten Hasselstrøm Jensen, Stine Hangaard

Abstract Aims Telemonitoring in type 2 diabetes (T2D) care has demonstrated positive trends in terms of glycaemic control. However, evidence regarding its impact on patient‐reported outcomes, such as general and diabetes‐specific quality of life (QoL), remains inconclusive. In particular, the effect of telemonitoring in people with insulin‐treated T2D is underexplored. This study aimed to evaluate the effect of telemonitoring on general and diabetes‐specific QoL compared with usual care in people with insulin‐treat …

18.08.2026journal-article

Mini-Reviews in Medicinal Chemistry

Nicotinamide Adenine Dinucleotide and Its Anti-aging Effects in the Context of Longevity and Menopause

Elifsena Canan Alp Arici, Esra Küpeli Akkol, Eduardo Sobarzo-Sánchez, Zeliha Selamoglu

Menopause is a complex biological condition associated with progressive estrogen depletion and increased susceptibility to several age-associated disorders. During this process, several biological mechanisms, such as mitochondrial dysfunction, oxidative stress, chronic inflammation, genomic instability, and immunosenescence, contribute to the progression of biological aging and metabolic imbalance. In this sense, nicotinamide adenine dinucleotide (NAD⁺) has progressively attracted attention because of its important …

18.08.2026journal-article

Nutrition Bulletin

Feeding Behaviours in Families With Children or Young People With Autism: A Systematic Review

Emma Tuschick, Jo Smith, Benjamin Harrison, Matthew Youngman, Lee Copping, Emma L. Giles

ABSTRACT Children and young people with autism often experience feeding difficulties and are at increased risk of food insecurity. However, the interplay between these challenges remains underexplored. This systematic review aimed to synthesise existing evidence on the prevalence and characteristics of feeding behaviours in families with children with autism, alongside associated factors such as sensory sensitivity and mealtime dynamics. Nine databases identified 399 records. Following screening, 88 original empiri …

18.08.2026journal-article

Transforming Government: People, Process and Policy

Information security policy as a governance capability in politically complex legislative organizations: a tridimensional configurational model

Elias Amaral dos Santos, Gabriel Oscar Cremona Parma

Purpose This conceptual paper aims to examine information security policy (ISP) in Brazilian state legislative assemblies as a formal document that may operate as an institutional governance device and, under specific conditions, become a governance capability. Design/methodology/approach The paper integrates sociological institutionalism, network governance and state-capacity perspectives, in dialogue with governance-oriented information security scholarship, to theorize the conditions under which ISP may become i …

18.08.2026journal-article

Journal of Sleep sciences

Prevalence and Risk Factors of Sleep Quality among Older Adults in Varamin, Iran

Hasan Ahmadi Gharaei, Fatemeh Ghorbani, Sara Naderpoor, Vida Alizad, Soodabeh Ghasemi, Zahra Hasanalizadeh, Foozieh Noori, Elham Momen Baghsiyahi

Background and Objective: The global aging population is increasing. Aging is associated with a gradual decrease in physiological activities and an increased risk of chronic diseases and sleep disorders. This study aimed to determine the prevalence and risk factors of sleep quality among elderly people. Materials and Methods: This cross-sectional study was conducted on 894 elderly individuals aged 60 years or older, selected using a multistage sampling method in Varamin City, Tehran Province, Iran. Data were collec …

18.08.2026journal-article

Experimental Physiology

Tackling aging and chronic disease: How space exploration and the ‘chameleon effect’ of pharmaceuticals can lead the way

Carina Kern, Tina Woods, Keith Siew

Abstract A common misconception surrounding space exploration is that humanity's pursuit of interplanetary travel, such as missions to Mars, is an escape from Earth. In reality, this endeavour offers an invaluable opportunity to address critical biomedical challenges here at home. The extreme conditions of space, including microgravity, cosmic radiation and prolonged isolation, create a natural laboratory for studying human biology under stress, allowing us to explore the boundaries of human resilience. These expos …

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18.08.2026journal-article

Journal of the American Geriatrics Society

Palliative Care Interventions for Patients With Kidney Disease: A Scoping Review by the Kidney Disease Aging Research Collaborative

Eleanor Rivera, Ilana Mittleman, Juliana Magro, Totini Chatterjee, Nidhi Ghildayal, Areeba Jawed, Jack Kimball, Jessica E. Ma, Fahad Saeed, Carly Weaver, Jordana Yahr, Mara McAdams‐DeMarco, Rasheeda K. Hall, Jennifer S. Scherer

ABSTRACT Background Chronic Kidney Disease (CKD) impacts ~40% of US adults aged ≥ 60 years. Palliative care, which can improve symptoms of serious illness, is underutilized in CKD despite it's association with a high symptom burden. We conducted a scoping review of palliative care interventions in CKD, with particular attention to older adults. Methods We searched PubMed, CINAHL, EMBASE, Cochrane Central, PsycInfo, ClinicalTrials.gov , and Web of Science for: (1) kidney disease; (2) palliative care; and (3) study d …

18.08.2026journal-article

Journal of the Medical Association of Thailand

Development of a Sarcopenia Score for Sarcopenia Screening in Community-Dwelling Older Adults

Unchalee Seekan, Worapong Sucharitpongpan

Background: Sarcopenia is common among community-dwelling older adults and is associated with increased risks of falls, disability, and mortality. Although several screening tools exist, many require specialized equipment or show limited diagnostic accuracy in community settings. Practical clinical prediction models using easily obtainable variables are therefore needed. Objective: To develop and internally validate a simple clinical prediction model and scoring system for screening sarcopenia in community-dwelling …

18.08.2026journal-article

Cardiology and Cardiovascular Research

Prevalence and Characteristics of Hypertension Among People Aged 60 Years and Older in Guediawaye, Senegal: A Population-based Cross-sectional Study

Ngone Gaye, Aliou Ngaide, Fatou Leye, Simon Sarr, Joseph Mingou, Marguerite Diouf, Malick Ndiaye, Momar Dioum, Mouhamadou Ndiaye, Alassane Mbaye, Maboury Diao, Abdoul Kane

Hypertension is a major determinant of cardiovascular morbidity and mortality, particularly among older adults, and in sub-Saharan Africa its screening and control remain insufficient despite the ongoing epidemiological transition. This study aimed to assess the prevalence of hypertension among people aged 60 years and older living in the Dakar suburbs and to describe their sociodemographic and clinical profile and associated risk factors. We conducted a quantitative, descriptive and analytical cross-sectional stud …

18.08.2026journal-article

Journal of the Association for Information Science and Technology

Failure in research? A methodological reflection on researching information behavior among older adults with diabetes in real‐world settings

Xiaoqian Zhang, Shun Yang, Yintao Wang

Abstract Questionnaire‐based designs remain central to information behavior research, yet the practical assumptions embedded in standardized survey administration are rarely examined. This paper offers a methodological reflection on five pilot studies conducted in preparation for a questionnaire‐based investigation of information behavior among older adults with type 2 diabetes. Across hospital outpatient clinics, rural households, senior learning institutions, residential care facilities, and social media platform …