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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
19.08.2026journal-article

Scandinavian Journal of Caring Sciences

Care Practices Supporting Older Adult Mobility in Institutional Long‐Term Care: An Ethnographic Study

Johanna Finskas, Minna Stolt, Riitta Suhonen, Noora Narsakka

ABSTRACT Background Older adults living in institutional long‐term care (ILTC) generally have decreased mobility, and their mobility care is often insufficient. Residents spend much of their day being sedentary, even though sedentary behaviour and inactivity are known to have many negative effects on health and functional capacity. More qualitative research describing care practices that support residents' everyday mobility in ILTC is needed. The aim of this study is to describe how care workers support residents' …

19.08.2026journal-article

Frontiers in Nutrition

Association of multidimensional biomarkers of immune, nutritional, inflammatory, and metabolic status with postoperative outcomes in older hip fracture patients: a systematic review and meta-analysis

Yuejiao Sun, Lei Wang, Lingling Sun, Yuetao Tang, Min Lei, Chunxia Zhou, Chunhua Guo

Background The high mortality and disability rates following hip fractures in the elderly have attracted widespread attention. Underlying inflammatory, immunological, nutritional, and metabolic imbalances are major contributing factors. However, the prognostic value of multidimensional composite biomarkers encompassing these dimensions remains unclear. This systematic review aimed to evaluate the prognostic value of these composite biomarkers for postoperative outcomes in elderly patients with hip fractures. Method …

19.08.2026journal-article

Applied Sciences

Exploratory Study for Personalized Assistive Technology Development: An Open-Source Korean Sip-and-Puff Mouse for People with Quadriplegia

Kwang-Ok An, Agnes Jihae Kim, Seon-Deok Eun

This study aimed to explore the key factors to consider when developing and sharing open-source assistive technology (AAT). To this end, the sip-and-puff mouse was selected from development requests submitted to the Korean Assistive Technology Open Platform. In this study, the sip-and-puff mouse was developed, applied, and shared as an open-source AAT for individuals with disabilities. The research was conducted based on usability feedback collected from five participants through three usability evaluations. During …

19.08.2026journal-article

Frontiers in Pharmacology

Differential fracture risk among proton pump inhibitors in older adults: evidence network and pharmacovigilance validation

Hui-ling Piao, Zeng-hao Wu, Ling-yun Zhou, Chang-hong Lai, Zhi-yao Tang, Wen-jun Yin, Yi-hu Yi

Background Proton pump inhibitors (PPIs) are the first-line therapy for acid-related disorders, with particularly high rates of chronic use in adults aged ≥65 years. Nearly all existing studies treat PPIs as a uniform drug class, overlooking potential heterogeneity in fracture risk across individual agents. This study aimed to evaluate the relative fracture risk of individual PPIs in elderly adults, using a complementary dual-method approach of network meta-analysis (NMA) and disproportionality analysis. Methods Fi …

19.08.2026journal-article

Frontiers in Nutrition

Diagnostic value of geriatric nutritional risk index and phase angle for malnutrition in patients with COPD: a retrospective cohort study

Xinxin Li, Yaying Yu, Lijing Cao, Shuangjian Huang, Kaiyue Fu

Background The incidence of malnutrition is relatively high among patients with chronic obstructive pulmonary disease (COPD). The main objective of this study was to explore and compare the discriminative ability of phase angle (PhA) and geriatric nutritional risk index (GNRI) tools for assessing malnutrition among hospitalized patients with COPD who underwent BIA assessment and had available serum albumin data based on the GLIM criteria. Methods This single-center retrospective study included 121 patients with hos …

19.08.2026journal-article

Frontiers in Neurology

Anti-amyloid treatment in Alzheimer disease: updated implications for patients with cerebral amyloid angiopathy and other cerebrovascular conditions

Matija Zupan, Polona Rus Prelog, Milica Gregorič Kramberger, Senta Frol

Anti-amyloid treatment (AAT) with monoclonal antibodies represents a major therapeutic advance in early Alzheimer disease (AD), but its introduction has important and underappreciated implications for vascular neurology. Because many patients with AD also have cerebral amyloid angiopathy and other cerebrovascular pathology, AAT influences stroke diagnosis, acute reperfusion therapy, and long-term antithrombotic management. Clinical trials of lecanemab and donanemab enrolled highly selected patients with minimal bas …

19.08.2026journal-article

Frontiers in Aging Neuroscience

Association between Alzheimer’s disease-related genes and neurodegenerative blood-based biomarkers in Indian adults

Hasan Abu-Amara, Wei Zhao, Zheng Li, Yuk Yee Leung, Gerard D. Schellenberg, Li-San Wang, Eileen M. Crimmins, Bharat Thyagarajan, Masroor Anwar, Perry Hu, Sharmistha Dey, Aparajit B. Dey, Xiang Zhou, Kumarasamy Thangaraj, Jinkook Lee, Sharon L. R. Kardia, Jennifer A. Smith

Background Alzheimer’s disease (AD) and related dementias are a growing health and economic burden in India. Blood levels of amyloid beta (Ab), tau, and other proteins marking neuronal injury are biomarkers of AD risk and are potentially important for AD prevention. Methods In 2,224 participants from the Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD), we performed gene-based analyses on (1) missense/loss-of-function (LoF) single-nucleotide variants (SNVs) and (2) b …

19.08.2026journal-article

Applied Sciences

Game-Based Interaction for Older Adults in Care Settings: Field Deployment and Multimodal Behavioral Data Processing

Qinzi Li, Zichao Zhou, Yangwei Ying, Hong Zhou

Care settings need short, accessible digital activities that encourage older adults to participate while generating process data during ordinary interaction. We developed a game-based platform with four activities: reflective choice, guided breathing, reminiscence, and artistic expression. Session video, interaction logs, and field notes were organized in a context-preserving multimodal framework. This exploratory seven-module field study included 12 older adults aged 65–90 years in a hospital-affiliated care setti …

19.08.2026journal-article

BMC Geriatrics

Assessing determinants of ageing in place through a capability approach: a qualitative study with older adults in Singapore’s public rental housing

Chao Min Tan, Yong Ling Ng, Dilyn Shu Xian Lee, Ming Kai Chua, Jowy Yi Hoong Seah, Lian Leng Low

Abstract Background Singapore is projected to be super-aged by 2026. Among its older adults, are those living in rental housing who may require a set of different factors to age in place, from their counterparts living in purchased flats. Methods This study seeks to understand the determinants and contexts of Ageing-in-Place (AIP) among older adults in public rental housing, using a capability AIP framework, and grounded in participants’ lived experiences. 66 older adults aged 60 and above (38 male and 28 female), …

19.08.2026journal-article

REVISTA DA FACULDADE DE DIREITO DA UFMG

MEMÓRIA, DEFICIÊNCIA COGNITIVA E DECISÃO JUDICIAL: RECONSIDERANDO O TESTEMUNHO NA DEMÊNCIA DO TIPO ALZHEIMER

Ana Paula Barbosa-Fohrmann, Michael Guedes

This article discusses the reliability of testimony from people with Alzheimer’s disease. It points out the inadequacy of the presumption that someone afflicted with this dementia cannot significantly contribute to the knowledge of facts relevant to a judicial process. This argument is developed in three parts. In the first, we present the notion of ableism and explain how it negatively affects evidentiary reasoning, leading to testimonial injustices. In the second, we explain Alzheimer’s as a progressive condition …

19.08.2026journal-article

The Gerontologist

Driving Retirement in Older Adults: A Qualitative Exploration into their Plans, Feelings and Support Needs

Jade Carpenter, Sjaan Koppel, Oscar Modesto, Thomas McGuckian, Benjamin Weir, Joanne M Bennett

Abstract Background and Objectives Driving retirement is a significant life transition for older adults (aged 65 and older), which has been associated with negative psychosocial and health outcomes. Research Design and Methods This qualitative study explores eight older adults’ plans, feelings and support needs when stopping driving. After focus groups were conducted, participants were categorised according to Adler and Rottunda’s (2006) groupings – Proactives, Reluctant Accepters and Resisters–to examine their nua …

19.08.2026journal-article

Frontiers in Pain Research

Management of pain for people with dementia living in nursing homes: stakeholders' perspectives on a prototype of a complex intervention

Caroline Kreppen Overen, Adelheid Hummelvoll Hillestad, Maria Larsson, Cecilia Olsson, Siren Eriksen

Background Healthcare personnel often report uncertainty about how to identify and alleviate pain in people with dementia. Up to 80% of nursing home residents with dementia are estimated to experience chronic pain. There is a lack of structured pain management interventions that focus on integrating and building upon the individual resources of people with dementia in the nursing home context. Although a prototype of such an intervention has been developed, further knowledge is needed regarding its functioning in c …

18.08.2026journal-article

People and Nature

Misperceptions of charismatic species' conservation status: Zoo visits and virtual exposure shape perceptions of extinction risk

Andrea Rizzardi Orlandi, Valentina Fulvia Isaja, Roberto Ambrosini, Ivan Jarić, Alessandra Costanzo

Abstract Biodiversity loss is accelerating globally, yet species are not equally affected, and public perceptions of extinction risk often diverge from scientific assessments. Understanding what shapes public perceptions is critical for effective conservation communication, particularly in zoos, where many people encounter exotic and endangered wildlife for the first time. Here, we investigated how visitors perceive the conservation status of charismatic species and which factors influence these perceptions in a mo …

18.08.2026journal-article

Frontiers in Public Health

Understanding core competencies of older adult care workers from the perspectives of the employer: automated content analysis of job advertisements

Meiling Chen, Weijue Wang, Meizhen Wu, Chunyan Jing

Objective This study aimed to examine employer-defined core competencies for older adult care workers in China. Methods From June to July 2025, we scraped 3,068 job advertisements for older adult care positions across 15 Chinese cities from three popular Chinese online recruitment sites. Based on the Iceberg Competency Model, we designed an analytic framework, which was then analyzed via automated content analysis (DivoMiner platform). Results The employer-stated competency requirements for older adult care workers …

18.08.2026journal-article

Healthcare

Stakeholder Perspectives on Identifying and Managing Comorbid Health Conditions Among Nursing Home Residents with Dementia: A UK Single-Site Qualitative Study

Hannah Lancaster, Frances Hawes, Eugene Y. H. Tang, Serena Sabatini

Background: This single-site qualitative interview study sought the opinions of 15 stakeholders from a nursing home based in the United Kingdom (UK) about identification and management of comorbidities in residents with dementia. Methods: Stakeholders were recruited through one of the nursing home owners, who acted as the gatekeeper. No residents with dementia were interviewed. Semi structured interviews were conducted online via Microsoft Teams in 2024. Data was analyzed using thematic analysis. Results: Stakehold …

18.08.2026journal-article

PLOS One

One year pre-diagnostic prevalence and associated factors of polypharmacy and potentially inappropriate medication use in community-dwelling adults with mild cognitive impairment or dementia in Norway (2014–2024): A registered report protocol

Hege Kersten, Tonje Marie Bø Vaksvik, Rita Romskaug, Torgeir Bruun Wyller, Keson Jaioun, Edoardo Botteri, Geir Selbæk

Background People with cognitive impairment frequently have multiple comorbidities, and polypharmacy is highly prevalent, affecting nearly half of individuals with mild cognitive impairment and dementia. The use of potentially inappropriate medications (PIMs), including those specifically problematic for cognitive impairment (PIMcog), increases with the total number of medications and may exacerbate cognitive symptoms or increase the risk of adverse drug events. However, the prevalence of polypharmacy and PIMcog us …

18.08.2026journal-article

The Journal of Cardiovascular Aging

Morphological analysis and multimodal deep learning for impedance cardiography feature localization and hemodynamic parameter estimation

Shuai Ma, Zeyue Xu, Zhengxu Yan, Ningxia Wu, Zhe Zhao, Huiquan Wang, Feng Cao

Aim: This study aimed to reduce the susceptibility of impedance cardiography (ICG) feature-point localization to waveform variability, noise, and inter-individual differences by developing an Electrocardiography (ECG)-ICG-phonocardiography (PCG) multimodal framework for beat-to-beat estimation of left ventricular ejection time (LVET), stroke volume (SV), and cardiac output (CO). Methods: Using the public HeartCycle multimodal dataset, ICG waveform polymorphism and class overlap were characterized using dynamic time …

18.08.2026journal-article

SLEEP Advances

Sleep health differences and night-to-night variability in people with and without HIV in Mwanza, Tanzania: Insights from actigraphy and sleep diaries

Godfrey A Kisigo, Martha Oshosen, Vanessa Nyamkomola, Ezekiel Mgema, Megan Willkens, Shelley Lees, Robert N Peck, Ana C Krieger, Saidi Kapiga, Kathy Baisley

Abstract Study Objectives This study had two objectives: (1) to compare objectively and subjectively measured sleep health between people living with HIV (PLWH) and people without HIV (PWoH) in Mwanza, Tanzania, and (2) to determine the number of nights of actigraphy and sleep diary monitoring required to obtain reliable estimates of habitual sleep. Methods We conducted a cross-sectional study among participants enrolled in the Mwanza HIV & CVD Cohort. Participants completed seven consecutive nights of wrist actigr …

18.08.2026journal-article

Frontiers in Public Health

Strengthening primary care gatekeeping for healthy aging in China: family doctor contract service and multidimensional health outcomes among older adults

Cangcang Jia, Zhengyang Wang, Ling Zhang, Jin Wang

Objective Expanding access to community-based primary care is central to addressing the health challenges posed by population aging in China. This study examines associations between Family Doctor Contract Service (FDCS) participation and multidimensional health outcomes among community-dwelling older adults. Methods Using nationally representative data from the 2023 China Longitudinal Aging Social Survey ( N = 11,455), we assessed three health dimensions: self-rated health, physical discomfort, and life satisfacti …

18.08.2026journal-article

npj Digital Medicine

Digital exclusion and health in older adults: a systematic review

Yucen Wu, Jun Pang, Shaoyong Xu, Aaron M. Lett

Abstract Healthcare systems are turning increasingly digital. Digital exclusion restricts access to a wider range of health-related resources among older adults, which delays prevention and treatment, posing additional health challenges. The study aims to systematically review the published evidence on digital exclusion and its implications for health outcomes among older adults. We conducted a systematic review following PRISMA guidelines (PROSPERO#CRD420250655824), searching five databases and major institutional …

18.08.2026journal-article

Frontiers in Nutrition

Microbial phenolic metabolites at the neurovascular interface: a precision-nutrition framework for brain aging

Sayandeep K. Das, Mamatha K, Savitri M. Nerune, Afsona Parveen, Prithviraj Karak

Brain aging is increasingly recognized as a neurovascular and inflammatory process involving blood–brain barrier dysfunction, endothelial activation, pericyte impairment, astrocyte–microglia reactivity, oxidative stress, white matter vulnerability, and cognitive decline. Although polyphenol-rich diets are widely associated with brain-health benefits, many parent polyphenols have limited systemic bioavailability, suggesting that gut microbiota-derived microbial phenolic metabolites may represent more biologically re …

18.08.2026journal-article

Materials

Low-Temperature Rheological Performance and Microscopic Aging Mechanism of SBS-Modified Asphalt Under Thermal-Oxidative and UV Aging

Keyan Ma, Yuwen Shi, Fucheng Guo, Yangyang Guo, Zhengchen Li, Di Wang

Ultraviolet (UV) radiation in high-altitude regions critically accelerates asphalt aging by inducing surface oxidation, molecular chain scission, and loss of low-temperature crack resistance. However, systematic comparisons of the macro-rheological and micro-chemical evolution between base asphalt and SBS-modified asphalt under UV aging remain insufficient. In this study, two types of asphalt (virgin and SBS-modified) were subjected to three aging protocols, namely short-term thermal oxidation (RTFOT), long-term th …

18.08.2026journal-article

Nutrients

Per-Capita Food Availability and Global Dementia Burden Across Multiple Exposure Windows

Carmelo Mario Vicario, Simona Massimino, Vanni Caruso, Carmelo M. Porto, Enrico Nicosia, Alessio Avenanti, Antonino Pennisi, Alessandra Falzone, Sebastiano Nucera, Antonina Lax, Antonino Germanò, Francesca Ferraioli, Sabrina Castellano, Angelo Quartarone, Francesco Tomaiuolo

Background/Objectives: Per-capita food availability may represent a large-scale indicator of nutritional environments potentially associated with dementia risk. However, whether national dietary environments are associated with dementia burden across different exposure periods remains unclear. Methods: We linked model-derived estimates of per-capita food availability based on Food and Agriculture Organization (FAO) food supply data for 2005, 2010, and 2015 with 2018 age-standardized dementia incidence, prevalence, …

18.08.2026journal-article

Journal of Intellectual Disabilities

Evaluating housing design for people with intellectual disabilities: Expert panel perspectives on key aspects of friendly housing

Adrián Jesús Ricoy-Cano, Ma Ángeles Quesada-Cubo, Virginia Fuentes-Gutiérrez, Yolanda María de la Fuente-Robles

Access to adequate housing is a fundamental right for people with intellectual disabilities; however, validated frameworks to assess inclusive housing environments remain limited. This study employed a multi-phase expert panel with 49 participants from four social profiles, including self-advocates with intellectual disabilities. Twenty-five indicators were assessed across three strategic dimensions—space, infrastructure, and management—using Likert-scale ratings and optional qualitative comments. Descriptive stati …