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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

Cognitive Therapy and Research

Investigating the Relationship Between Insight and Metacognition in Anxiety Treatment: Results from an Online Imagery Rescripting Intervention

Asala Halaj, Hila Sorka-Ella, Jonathan D. Huppert, Anthony S. David

Abstract Background Imagery Rescripting (IR) has shown promise in reducing anxiety symptoms and improving coping skills, but who benefits most may depend on individual factors. Insight refers to recognizing symptoms as abnormal and in need of treatment, while metacognitive beliefs are beliefs that people hold about their own thoughts, such as beliefs about their uncontrollability or danger. Both may shape treatment outcomes. Objective This study examined pre-post changes in insight and anxiety symptoms following an …

26.08.2026journal-article

JMIR Mental Health

Large Language Models as a New Tool for Therapists in Internet-Based Cognitive Behavioral Therapy: Blinded Clinician Rating Pilot Experiment

Thomas Tandrup Lamm, Arthur Bran Herbener, Oliver Rønn Christensen, Malene Flensborg Damholdt, Kaare Bro Wellnitz, Heidi Frølund Pedersen, Lisbeth Frostholm

Background Internet-based cognitive behavioral therapy (iCBT) is an effective and scalable alternative to face-to-face psychotherapy, but its reach is constrained by the time therapists spend reviewing patient input and manually drafting written responses. Studies suggest that large language models (LLMs) may be capable of generating high-quality therapeutic text, with the potential to support therapists in delivering treatment. Their suitability as therapist-support tools in structured iCBT, however, remains insuf …

26.08.2026journal-article

Frontiers in Cardiovascular Medicine

Design and rationale for MICROFIT (Microvascular Coronary Rehabilitation For Improving Treatment)—a feasibility randomized trial of intensive lifestyle rehabilitation for symptomatic coronary microvascular dysfunction

Joanna Abramik, David Murphy, John Graby, Anna Lacey, Theresa Smith, Christopher Lawton, Faith Martin, Fiona Gillison, Matthias G. Friedrich, Amedeo Chiribiri, Mark Mariathas, Kevin Carson, Jonathan Carl Luis Rodrigues, Dylan Thompson, Ali Khavandi

Background Coronary microvascular dysfunction (CMD), a common endotype of angina with non-obstructed coronary arteries (ANOCA), is linked to poor cardiovascular outcomes, and can significantly impact quality of life, mental health, and functional capacity. CMD management strategies focus on symptom control with antianginal therapies, with limited effect and prognostic benefit. While lifestyle changes and risk factor modification are advocated by international guidelines, evidence supporting cardiac rehabilitation f …

26.08.2026journal-article

Russian Bulletin of Obstetrician-Gynecologist

Evaluation of the effectiveness of local hormone therapy in older patients with pelvic descension

N.V. Yudina, A.E. Brylyaeva, S.N. Buyanova

Objective. To evaluate the results of pelvic descension correction in patients of the older age group on the background of combined treatment, including surgical intervention in combination with the use of local hormone therapy at the stages of preoperative preparation and postoperative rehabilitation. Materials and methods. The prospective study was conducted from 2024 to 2025 on the basis of the Moscow Regional Research Institute of Obstetrics and Gynecology named after Academician V.I. Krasnopolsky. The study in …

26.08.2026journal-article

Advanced Functional Materials

Halogen‐Engineered Covalent Organic Framework Hydrogel for Efficient Photocatalytic Hydrogen Release in Atopic Dermatitis Therapy

Jieyue Liao, Shengjie Xue, Shuai He, Longlong Mu, Yingnan Luo, Shiyu Ni, Yunlei Zhou

ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease with intractable pruritus and barrier disruption. Current therapies offer limited efficacy and are associated with adverse effects, highlighting the urgent need for safer alternatives. Hydrogen (H 2 ) shows anti‐inflammatory and antioxidant potential, but effective topical delivery remains challenging. Herein, we report a halogen‐modulated covalent organic framework (COF) hydrogel that integrates a “halogen‐engineered internal electric field” st …

26.08.2026journal-article

Bulletin of Faculty of Physical Therapy

Current state of entry-level geriatric physiotherapy curriculum in Kenya

Karen M. Blood, Justin T. Mierzwicki, Barbara Billek-Sawhney

Abstract Background Kenya is experiencing a shift in the demographic profile towards a higher percentage of older adults. Physiotherapists must possess a strong knowledge base to meet the unique needs of older adults to ensure quality outcomes. The purposes of this study were to evaluate the level of preparation of Kenyan physiotherapists related to the examination and treatment of older adults and identify the format with which geriatric physiotherapy education is delivered in entry-level physiotherapy programs. M …

26.08.2026journal-article

The American Journal of Interdisciplinary Innovations and Research

Beyond Behavior: A New Perspective on Autism through Existential Therapy

Merouane Elmaazouzi

Autism Spectrum Disorder (ASD) presents unique challenges in social interaction and communication, often addressed through traditional behaviorist approaches that focus on modifying observable behaviors. However, such methods may overlook the existential needs of individuals with ASD, potentially leading to dehumanizing effects. This article advocates for the integration of existential therapy as a more holistic and human-centered psychotherapeutic intervention, emphasizing principles such as freedom, authenticity, …

26.08.2026journal-article

Biomedicines

Physical Recovery After CAR-T Cell Therapy vs. Autologous Stem Cell Transplantation Assessed Through Quantitative Rehabilitation Measures

Flavio Feri, Yuliya Hutsava, Rita Monico, Francesco Morena, Vincenzo Maria Perriello

Introduction: Chimeric Antigen Receptor T (CAR-T) cell therapy and autologous stem cell transplantation (ASCT) are both associated with significant physical and psychological challenges during post-transfusion recovery. To date, most assessments of physical recovery rely on subjective measures, which are prone to individual perception and bias. Direct comparative data on objective physical function between these therapies remain lacking. Objective: The study aims to compare physical recovery trajectories following …

26.08.2026journal-article

Buildings

Artificial Intelligence for Structural Condition Assessment and Rehabilitation: Recent Advances and Future Directions

Shima Zare, Mohammad Najafi

The growing need to ensure the safety, resilience, and sustainability of existing building structures has accelerated the adoption of artificial intelligence (AI) for structural condition assessment and rehabilitation. This critical narrative review synthesizes 82 retained sources, including 33 application-oriented sources, through a transparent, structured literature search and study-selection process; it is not a formal systematic review or meta-analysis. To organize this fragmented evidence base, the review intr …

26.08.2026journal-article

Respirology

Comparison of Efficacy Between Non‐Invasive Ventilation and High‐Flow Nasal Cannula Oxygen Therapy in Treating Acute Pulmonary Edema

Qiaoyun Huang, Jianyi Niu, Shanshan Zha, Zhenfeng He, Xueying Fan, Luqian Zhou, Rongchang Chen, Lili Guan

ABSTRACT Background and Objective Non‐invasive ventilation (NIV) is the first‐line treatment for acute pulmonary edema (APE). However, with the development of high‐flow nasal cannula oxygen therapy (HFNC), recent small‐sample prospective studies have suggested comparable efficacy between HFNC and NIV in treating acute cardiogenic pulmonary edema. To further evaluate the efficacy of these two respiratory support modalities, we directly compared their outcomes using data from two public databases, aiming to provide h …

26.08.2026journal-article

Cytotherapy and Longevity

Regulatory Evolution and Transformation of China's Cell and Gene Therapy Industry

Wei Li, Zhen Qin, Xiujuan Wang, Xiu'e Wang, Jing Wen, Yichen Shi, Chunlin Mou

Cell and gene therapy (CGT) products have driven a global transformation in medicine, opening new avenues for the diagnosis and treatment of major diseases, while also posing new challenges to regulatory agencies worldwide. In the context of the current global CGT industry landscape, this article systematically reviews the evolution of China's CGT regulatory framework over the past three decades, delves into the stages of regulatory development, and analyzes the profound impact of regulatory policies in different p …

26.08.2026journal-article

Journal of Endovascular Therapy

Safety-Oriented Endovascular-First Revascularization for Proximal Subclavian Artery Chronic Total Occlusion: Real-World Strategy Selection and Mid-Term Outcomes

Tao Shi, Jie Fang, Mingyao Luo, Yongbao Zhang

Purpose: To report real-world outcomes of a safety-oriented, endovascular-first strategy for proximal atherosclerotic subclavian artery chronic total occlusion (CTO) and to develop a pragmatic computed tomography angiography (CTA)-based open-first consideration aid for anatomically unfavorable cases. Materials and Methods: This single-center retrospective study included consecutive patients treated between January 2020 and December 2024. Endovascular-first revascularization was pursued when feasible, with bypass us …

26.08.2026journal-article

Journal of Cancer Research and Therapeutics

Advances and future perspectives in the treatment of small cell lung cancer: From chemotherapy and radiotherapy to the era of targeted therapy and immunotherapy

Xiangwei Cheng, Weibin Lv, Linfeng Wu, Yifan Wang, Yiping Zhu

ABSTRACT Small cell lung cancer (SCLC) is an aggressive malignant tumor that mainly originates from pulmonary neuroendocrine cells and is characterized by rapid proliferation, high metastatic potential, and acquired therapeutic resistance. The therapeutic landscape for SCLC is largely confined to traditional modalities, such as surgery and chemoradiotherapy. However, 80–85% of patients are diagnosed with extensive-stage SCLC at initial presentation; surgical intervention and radiotherapy are often not applicable fo …

26.08.2026journal-article

ACTA MEDICA IRANICA

Reducing Pain in the First Stage of Labour Using Counter-Pressure Therapy in the Indonesian Hospital

Sri Rejeki, Satriya Pranata, . Machmudah, Arief Yanto, Lalu Muhammad Irham, Tri Hartiti, Aric Vranada

Inadequately managed labor pain can negatively impact the birthing process. Potential adverse effects of labor pain include stress, fatigue, impaired breathing patterns, inhibited oxytocin production, psychological distress, and an increased risk of medical interventions. Counter-pressure is a safe nursing intervention used to alleviate labor pain. This study aimed to determine the effect of counter-pressure on intrapartum maternal pain. A pre-experimental, one-group pretest-posttest design was utilized, focusing o …

26.08.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Neurodynamic mobilization for the management of patients with lumbar disc herniation: A randomized controlled study

Gurkan Gunaydin, Mubeccel Nur Karaduman, Omer Osman Pala, Zeynep Hazar, Seyit Citaker

Background Low back pain is a major cause of disability worldwide. Due to the limited effectiveness of current treatments, this study evaluated the efficacy of neurodynamic mobilization technique on pain intensity, range of motion (ROM), neurodynamics, functional status, and disability. Methods Thirty-seven patients were randomized to control or mobilization group. The control group received conventional therapy, while the mobilization group received neurodynamic mobilization plus electro/thermal therapy for 4 week …

26.08.2026journal-article

Journal of General Health Sciences (JGEHES), Necmettin Erbakan University

Occupational Anxiety, Psychological Resilience, and Alienation in Prehospital Emergency Health Workers

Onur GÖZÜBÜYÜK

Bu araştırmanın amacı, hastane öncesi acil sağlık hizmeti çalışanlarında mesleki kaygı, psikolojik sağlamlık ve işe yabancılaşma arasındaki ilişkinin incelenmesidir. Araştırmanın verileri, 1 Mayıs - 31 Ağustos 2024 tarihleri arasında Türkie'de görev yapmakta olan 393 hastane öncesi acil sağlık hizmeti çalışanından toplanmıştır. Veri toplama sürecinde çevrim içi anket yöntemi kullanılmıştır. Verilerin analizinde tanımlayıcı istatistiksel yöntemler, korelasyon ve regresyon analizleri uygulanmış ve sonuçlar %95 güven …

26.08.2026journal-article

Frontiers in Neurology

Clinical presentation and engagement with a cognitive rehabilitation clinic in individuals reporting anomalous health incidents

Kelly Marshall, Katherine Sullivan, Louis M. French

Introduction The Department of Defense is working to establish effective rehabilitative management options for individuals who have experienced Anomalous Health Incidents (AHI). Methods This retrospective, observational study conducted at Walter Reed National Military Medical Center describes the clinical presentation of forty patients (21 female and 19 male; mean [SD] age, 43.3 [9.2] years) with reported AHI. It also describes the application of a cognitive training intervention, its utilization, patient satisfact …

26.08.2026journal-article

Frontiers in Medicine

ChatGPT-generated rehabilitation programs in sports physiotherapy: an expert evaluation and a mixed-methods study of clinical applicability

Adem Cali, Mehmet Erdem Yorukoglu, Gorkem Acar, Ertugrul Safran

Background Individualized rehabilitation supports safe return to sport, yet clinical workload may limit personalized program design. This study evaluated ChatGPT-4.1-generated programs for five sports injury scenarios using a structured rubric scored by two independent sports physiotherapy experts and examined inter-rater reliability and clinical applicability. Methods Mixed-methods design combining rubric scoring with deductive qualitative content analysis of expert commentary. Five cases covered muscle (hamstring …

26.08.2026journal-article

Journal of Clinical Oncology

Medical Therapy for Hormone Receptor-Positive, HER2-Negative Stage I-III Breast Cancer: ASCO Living Guideline, Version 2026.1.0

Jennifer L. Caswell-Jin, Mark R. Somerfield, Muhammad Ali Khan, Gretchen G. Kimmick, Shilpi Gupta, Kara Kenan, Namrata Peswani, Dawn L. Hershman, Brenda J. Ernst, Brittany E. Harvey, Gregor Krings, Nicholas P. McAndrew, Irbaz Bin Riaz, Ines Vaz-Luis, Cynthia Villarreal-Garza, Japneet Kaur Oberoi, Muhammad Hussnain Sadiq, Huan He, Ramaa Chitale, Michael J. Hassett

PURPOSE To provide recommendations on use of medical therapies for patients with stage I-III hormone receptor-positive, HER2-negative breast cancer. METHODS An Expert Panel including patient representation completed a systematic review of the evidence and formulated recommendations for practice. Eligible studies included patients with stage I-III hormone receptor-positive, HER2-negative breast cancer and evaluated neoadjuvant or adjuvant chemotherapy, endocrine therapy, immunotherapy, or targeted therapy. Outcomes …

26.08.2026journal-article

PLOS One

Implementation of objective structured clinical examination among midwifery and nursing educators at South and Central Region Universities in Ethiopia, 2023

Zerihun Demessie Dilebo, Bekana Fekecha Hurissa, Kebenesa Angasu Kitaba

Introduction The Objective Structured Clinical Examination (OSCE) is a well-known clinical skill evaluation tool that has been applied worldwide to teach and assess learners’ competencies in healthcare disciplines. Poor implementation of OSCE can lead to inaccurate assessments and ultimately result in the production of incompetent professionals. However, there is no evidence of the implementation status and factors that limit the much-needed OSCE practice in the study area. Objective To assess OSCE implementation a …

26.08.2026journal-article

Linguistics Vanguard

Smiles can be conveyed to listeners via speech signals: a case study with Japanese labiodentalization

Shigeto Kawahara, Kimi Akita, Zen Nagatsuka, Julián Villegas

Abstract One long-standing question in speech communication research concerns the extent to which an emotional state is encoded in the acoustic signal and conveyed to the listeners. To address this question, we deployed a recent finding in Japanese, in which speakers replace bilabial sounds (e.g. [b]) with labiodental sounds (e.g. [v]) when speaking with a smile. Experiment 1 used stimuli recorded by two professional voice actors under four conditions crossing two factors, voice quality (smile vs. non-smile) and ar …

26.08.2026journal-article

Frontiers in Oncology

Minimal residual disease guides postoperative therapy in a patient with ALK-rearranged adenocarcinoma: a case report

Xinghong Xian, Ke Wang, Liwen Wang, Hua Ke

This case report explores the role of circulating tumor DNA (ctDNA)-based minimal residual disease (MRD) monitoring in predicting tumor recurrence or metastasis after consolidative surgery in a patient with ALK-rearranged non-small cell lung cancer (NSCLC). We present a case of a 43-year-old female patient with stage IVA ALK-rearranged NSCLC who initially responded to six months of Alectinib targeted therapy, underwent consolidative surgery with postoperative pathology confirming complete response in the resected p …

26.08.2026journal-article

Frontiers in Immunology

Advancing precision tacrolimus therapy: a systems genetics dissection in BXD platform

Wei Zhou, Xin-Bo Wang, Yu-Wei Guo, Bing Hu, Zi-Xuan Wang, Yu Xiong, Xuan-Ming Chen, Bo-Yang Xu, Xiao-Xing Wang, Xiao-Xue Wang, Fei-Fei Han, Jun-Jie Wang, Hao-Jun Zhang, Liang Peng, Li-Li Gong, Lu Lu, Li-Hong Liu

Background Tacrolimus is a core immunosuppressant in organ transplantation, but its narrow therapeutic window and significant pharmacokinetic variability hinder precision dosing. Although CYP3A5-guided strategies have established clinical relevance for tacrolimus initial dose adjustment, they do not fully account for the marked interindividual variability in tacrolimus exposure, highlighting the need for complementary models to decode more complex genetic regulation. This study aimed to identify candidate genetic m …