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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
20.08.2026journal-article

Frontiers in Public Health

Construction strategies and implementation pathways of resilience governance system for care risks in older adult care institutions from a social-ecological perspective

Chunyan Li, Yang Xie, Weiping Liu

Against the backdrop of population ageing, the governance of care risks in older adult care institutions has become a global challenge. This paper aims to construct a resilience governance system for care risks in older adult care institutions based on social-ecological systems theory, exploring its construction strategies and implementation pathways. The article first reviews the development trajectory of resilience governance theory in social sciences, then introduces social-ecological systems theory into the res …

20.08.2026journal-article

Archives of Medical Science

The unequal burden of interstitial lung disease mortality in older US adults: a 22-year analysis and projections to 2030

Tong Feng, Pengcheng Zheng, Yue Cao, Ding Han, Ran Duan

Introduction Interstitial lung disease (ILD) comprises a heterogeneous group of disorders characterized by progressive lung fibrosis, respiratory failure, and substantial mortality, particularly among older adults. While prior studies have described historical ILD mortality trends, comprehensive analyses incorporating future projections, detailed geographic disparities, and socioeconomic variation remain limited. Material and methods We analyzed CDC WONDER underlying-cause-of-death data for US adults aged ≥ 65 year …

20.08.2026journal-article

Aging Cell

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise‐Induced Redox Responses in Human Skeletal Muscle

Bradley A. Ruple, Nicholas A. Carlini, Jason S. Kofoed, Helya Rostamkhani, Brady E. Hanson, Jesse C. Craig, Shelby C. Osburn, Allison M. Manuel, Paul A. Stewart, Jonathan Wanagat, Ryan M. Broxterman, Joel D. Trinity

ABSTRACT Redox imbalances and mitochondrial dysfunction are key contributors to age‐related declines in skeletal muscle and may contribute to impaired exercise responsiveness. Here, we investigated the influence of aging on skeletal muscle redox at rest and in response to acute exercise, examining how mitochondrial quality and quantity relate to skeletal muscle redox status. Skeletal muscle biopsies were obtained from 12 young (22 ± 4 years) and 10 older adults (66 ± 7 years) before and immediately after 60‐min of …

03.09.2026journal-article

Schizophrenia Bulletin

Cognitive Behavior Therapy for Psychosis in People with Intellectual Disability—A Scoping Review

S R Vogels, A B P Staring, J de Jager

Abstract Background and Hypothesis Cognitive behavior therapy for psychosis (CBTp) is effective in reducing psychiatric symptoms. Most CBTp trials have excluded patients with intellectual disabilities, even though intellectual disabilities are associated with an at least 3 times higher psychosis prevalence. More understanding of evidence-based approaches for this population is needed. The aim of this review was to assess the current state of knowledge about CBTp for people with both intellectual disabilities and ps …

20.08.2026journal-article

Frontiers in Nutrition

Luteolin promotes healthy aging in adult females but shortens lifespan after embryonic exposure in Drosophila melanogaster

Quanyong Wu, Boya Ouyang, Hui Cao, Min Zhang, Mohamed A. Farag, Thomas Efferth, Jesus Simal-Gandara, Jianbo Xiao

Introduction Luteolin is a dietary flavonoid widely distributed in fruits, vegetables, and medicinal plants and is recognized for its antioxidant and health-promoting properties. However, its effects on physiological aging and the influence of developmental stage and biological sex remain poorly understood. Methods In this study, Drosophila melanogaster was exposed to luteolin during either adulthood or embryonic development and evaluated for lifespan, healthspan, metabolic regulation, and aging-related molecular c …

20.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

AVANÇOS E DESAFIOS NA INCLUSÃO DE PESSOAS COM DEFICIÊNCIA EM ESCOLAS DO CAMPO NO DISTRITO DE SÃO GONÇALO, SOUSA-PB

Luzenira Carneiro Lacerda, Helmara Giccelli Formiga Wanderley Junqueira, Paulo Abrantes de Oliveira, Sthelio Braga da Fonseca, Girlan Guedes dos Santos, Michael Douglas Sousa Leite

A inclusão escolar de estudantes com deficiência em contextos rurais constitui um desafio que envolve condições pedagógicas, estruturais e sociais específicas. Nesse contexto, esse estudo teve como objetivo analisar a percepção dos responsáveis legais dos estudantes com deficiência acerca do processo de inclusão escolar nas escolas rurais do Distrito de São Gonçalo, em Sousa (PB), considerando acesso, infraestrutura, recursos de apoio, barreiras e participação familiar. Trata-se de estudo de caso, exploratório e de …

20.08.2026journal-article

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Walkability im Alter – Umweltfaktoren der Wohnumgebung und funktionssensitive Messung im urbanen Raum

Daniela Koller, Eva Grill, Ralf Strobl

Zusammenfassung Walkability beschreibt die Gehfreundlichkeit einer Nachbarschaft und ist ein zentrales Konzept zur Förderung von Mobilität, körperlicher Aktivität und sozialer Teilhabe im Alter. Bestehende Ansätze bilden die spezifischen Bedürfnisse älterer Menschen bislang nur unzureichend ab, insbesondere bei funktionellen Einschränkungen. Der Beitrag zeigt, wie Walkability im höheren Lebensalter konzeptionell weiterentwickelt, funktionssensitiv erfasst und in einem urbanen Kontext empirisch untersucht werden kan …

20.08.2026journal-article

Scandinavian Journal of Public Health

Future trends in dementia incidence and mortality: projecting the burden of dementia on long-term care in Finland by 2040

Maria Guzman-Castillo, Kaarina Korhonen, Michael Murphy, Pekka Martikainen

Aims: We projected the future number of individuals with dementia and long-term care (LTC) residents in Finland by education level through 2040. We also examined the impact of different future scenarios regarding declining dementia and LTC trends, as well as the effect of past educational expansion on the future prevalence of dementia and LTC. Methods: A multistate model tracks the population aged 65 years and over through states characterised by the presence of dementia, LTC residence, or death. We calculated age, …

20.08.2026journal-article

Aging Cell

Molecular Mechanisms of Age‐Related Taste Dysfunction Deciphered by Spatiotemporal Transcriptomics

Wandong Zhao, Xudong Cha, Yingqi Xie, Enhao Wang, Wenlu Xing, Zengyi Xu, Langchao Liang, Changhai Xiong, Morong Zhou, Penghui Fu, Zhe Wang, Xin Liu, Yiqun Yu, Huanhai Liu, Hanbo Li, Wenwen Ren

ABSTRACT Age‐related taste dysfunction impairs nutrition and quality of life, contributing to metabolic disorders and frailty in the elderly, yet its cellular and molecular basis remains poorly understood. By integrating single‐cell RNA and spatial transcriptomics sequencing, we systematically mapped murine taste bud aging across five developmental stages from neonatal to aged. Our findings reveal that age‐associated taste impairment is driven by the progressive depletion of stem/progenitor cell differentiation cap …

19.08.2026journal-article

Horizonte Sanitario

Adaptación transcultural de la escala de estrés en personas con hipertensión arterial

Doris Berdazco Pintado, Ana Laura Carrillo Cervantes, Nissa Yaing Torres Soto, Reyna Torres Obregón

Objective: To adapt and validate the "Stress Scale for People with Arterial Hypertension" for its subsequent use in the assessment of stress in hypertensive patients. Materials and methods: An observational, cross-sectional study was conducted. An anonymous and voluntary survey was administered. The sample consisted of 181 individuals (110 women and 71 men) residing in the city of Saltillo, Coahuila, Mexico, with diagnosis of arterial hypertension, with a mean age of 55.34 years (SD = 13.93). The instrument include …

19.08.2026journal-article

Australasian Journal on Ageing

Upskilling Allied Health Professionals and Judo Coaches to Teach Safe Falling Skills to Older Adults: A Train‐the‐Trainer Intervention

Agathe Daria Jadczak, Meera Verma, Michael Headland, Renuka Visvanathan

ABSTRACT Objectives Learning safe falling skills, adapted from judo, is a promising strategy to reduce the risk of falls and fall‐related injuries in older adults. This study aimed to upskill allied health professionals and judo coaches to teach safe falling skills to community‐dwelling older adults. Methods A Train‐the‐Trainer program including a 2‐day workshop (13 h) on teaching safe falling and how to work with older adults, followed by weekly attendance at an 8‐week judo‐based safe falling program for older adu …

19.08.2026journal-article

Journal of Human Hypertension

The association between mobility and asleep blood pressure alterations in frail and non-frail adults 80 years and older

Fernando G. Blauth, Fernando L. Scolari, Laís A. S. Vilar, Victor C. B. Pontes, Vanessa B. V. de Carvalho, Júlio C. Moriguti, Nereida K. Lima

Abstract The influence of mobility on asleep blood pressure among adults aged 80 years and older, particularly considering frailty, remains poorly understood. This cross-sectional study aimed to examine the association between objectively measured mobility parameters and asleep blood pressure alterations in a frail and non-frail population aged 80 years and older. Seventy-one participants (mean age 85 ± 4 years; 33 non-frail and 38 frail) completed both ambulatory blood pressure monitoring (ABPM) and objective mobi …

19.08.2026journal-article

Frontiers in Psychiatry

Effects of visual art therapy on cognitive function in older adults: a systematic review and meta-analysis

Zhenhua Guo, Yingcong Liu, Shan Zhu, Yupeng He

Objective To systematically review the evidence on the effects of visual art therapy on global cognitive function in older adults, and to examine its impact on verbal fluency, naming ability, and activities of daily living. Methods A systematic search was conducted in PubMed, Web of Science, Embase, the Cochrane Library, China National Knowledge Infrastructure (CNKI), the Chinese Biomedical Literature Database, Wanfang Database, and VIP Database for randomized controlled trials (RCTs) published from database incept …

19.08.2026journal-article

Gerontology

construction and evaluation of sarcopenia risk prediction model for non-obese older adults

Xin Liu, Shichen Wang, Yanan Wei, Qian Xue, Jingtong Wang

Introduction: Sarcopenia is common in older adults, with distinct features in non-obese individuals. This study developed and validated a nomogram to predict sarcopenia risk specifically in non-obese older adults. Methods: Data from 1,654 CHARLS participants were used for model development and internal validation, and 263 NHANES participants for external validation. LASSO regression selected predictors. A nomogram was constructed and assessed using AUC (discrimination), calibration curves (accuracy), and decision c …

19.08.2026journal-article

Journal of the American Geriatrics Society

Geriatric Medicine Competencies in Postgraduate Training Programs Across Specialties

Janani Thillainadesan, Grace Pearson, Gregory M. Ouellet, Marcia C. Mecca, Terri R. Fried, Tim J. Wilkinson

ABSTRACT Background Aging populations require physicians skilled in competencies essential for the care of older adults. The extent to which such geriatric competencies are included in non‐geriatric postgraduate medical training programs is not known. Therefore this study examined the inclusion of 13 geriatric competencies in postgraduate training programs in Australia and New Zealand, the United Kingdom, and the United States. Methods Thirteen core geriatric competencies were identified and defined: aging physiolo …

19.08.2026journal-article

JMIR Aging

Demoralization and Mental Disorders in Community-Dwelling Older Adults: Cluster Analysis

Alice Onofrio, Maria Ferrara, Ilaria Domenicano, Martino Belvederi Murri, Tommaso Toffanin, Maria Giulia Nanni, Alessandra Canuto, Kerstin Weber, Jana Volkert, Holger Schulz, Martin Härter, Sylke Andreas, Luigi Grassi

Abstract Background Demoralization negatively affects the quality of life, especially in people with mental disorders. Objective This study aims to assess demoralization in a cohort of community-dwelling older adults, to identify groups of individuals who share similar characteristics in terms of mental health conditions and the severity of demoralization domains, and to investigate the different characteristics across these groups. Methods Participants were enrolled in 3 centers as part of the cross-sectional Ment …

19.08.2026journal-article

Frontiers in Aging Neuroscience

Tai Chi for improving motor symptoms in Parkinson’s disease patients: a systematic review of mechanisms

Zhi Li, Xiupan Wei, Pengyi Gao, Jiayi Zhang, Qian Wang, Pei Wang, Ting Zhou, Hongxing Wang

Background In recent years, Tai Chi (TC) training has played an increasingly important role in the management of motor disorders in Parkinson’s disease (PD) patients. A thorough understanding of the therapeutic mechanisms of TC is crucial for optimizing its clinical efficacy. The long-term practice of TC has been shown to enhance patients’ balance and postural stability, thereby reducing the risk of falls and improving their walking ability. Objectives This systematic review seeks to elucidate the mechanisms throug …

19.08.2026journal-article

EDUJAVARE: International Journal of Educational Research

Multicultural Education from an Islamic Perspective and Its Relevance to the Lives of the People of Papua

Muhammad Irwan Putra, Yudha Dharma Buana, Florensia Ruri Renaningtyas

This article specifically examines the concept of multiculturalism from an Islamic perspective by relating it to the social realities of communities in Papua. Based on a conceptual and normative study, Islam views plurality as sunnatullah, meaning that diversity is part of God’s natural order; therefore, universal values such as justice, brotherhood (ukhuwah insaniyyah), and tolerance constitute important foundations for peaceful social life amid differences. Through an integrative approach that connects the teachi …

19.08.2026journal-article

Journal of Parkinson’s Disease

Rehabilitation strategies for atypical parkinsonian syndromes: A scoping review of progressive supranuclear palsy, multiple system atrophy, corticobasal syndrome, and dementia with Lewy bodies

Hikaru Kamo, Satoru Amano, Isabelle K Gerzenshtein, Dinesh K Vuddandam, Koichi Nagaki, Mai Shimizu, My-Vy Tran, Arunmozhimaran Elavarasi, Nikolaus R McFarland, Aparna Wagle Shukla

Background Rehabilitation plays a crucial role in maintaining function and independence in neurodegenerative disorders. However, evidence on its effectiveness in atypical parkinsonian syndromes including progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal syndrome (CBS), and dementia with Lewy bodies (DLB) remains fragmented. Objective This scoping review aimed to comprehensively map the literature on rehabilitation interventions for PSP, MSA, CBS, and DLB, summarize intervention types …

19.08.2026journal-article

Frontiers in Political Science

The political representation of peoples and nationalities in Ecuador. Indigenous peoples and nationalities, Afro-Ecuadorian people, and Montubio people: the political underrepresentation of peoples and nationalities in Ecuador

Koya Saucisa Shugulí

This study analyzes the political underrepresentation of Indigenous, Afro-Ecuadorian, and Montubio peoples and nationalities in Ecuador’s National Assembly. According to official population data, these groups collectively account for 20.2% of the country’s population. However, in the 2025 general elections, they secured only 20 of the 151 seats, compared to the approximately 30.5 seats that would correspond to a strict proportional distribution. The study employed a mixed-methods design combining official demograph …

19.08.2026journal-article

Frontiers in Nutrition

Adherence to the Mediterranean diet and incident cardiovascular outcomes among older adults

Emanuele Marzetti, Riccardo Calvani, Isabel Rodriguez-Sanchez, Samuel da Silva Aguiar, Anna Picca, Matteo Tosato, Stefano Cacciatore, Francesco Landi, Helio José Coelho Júnior

Aim The present study examined the prospective associations between adherence to the Mediterranean (MED) diet, its individual components, and incident cardiovascular disease (CVD) among community-dwelling older adults. Methods Data were obtained from the English Longitudinal Study of Ageing (ELSA). Participants aged ≥65 years without hypertension at baseline (Wave 9, 2018–2019) were followed through Wave 11 (2023–2024). Adherence to the MED diet was assessed using the Medi-Lite score. Incident hypertension, myocard …

19.08.2026journal-article

Alzheimer Disease & Associated Disorders

Dementia With Extensive Giant Perivascular Spaces as a Mimicker of Alzheimer Disease

Aliakbar Netterwala, Thomas Mathew, Allen Johnson, Shagun Bhardwaj

Giant perivascular spaces (PVS) are usually incidental magnetic resonance imaging findings, but rarely may present with progressive cognitive decline. We report the case of a 70-year-old woman with a 3-year history of gradually progressive amnestic-predominant dementia associated with impairment in instrumental activities of daily living and multidomain deficits on formal cognitive testing. Magnetic resonance imaging of the brain demonstrated extensive bilateral giant cystic spaces in the subcortical, deep, and per …

19.08.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Social, economic, and environmental disparities in device-measured 24-hour movement behaviours in a nationally representative cohort of older English adults

Laura Brocklebank, Andrew Steptoe, Mikaela Bloomberg, Aiden Doherty

Abstract Background Insufficient physical activity, excessive sedentary time, and suboptimal sleep duration (i.e., not excessively short or long) are linked to morbidity and premature mortality and may contribute to health inequalities, but device-measured, nationally representative data capturing the full 24-hour movement spectrum remain scarce, particularly among older adults. This study examined social, economic, and environmental disparities in 24-hour movement behaviours in the 2021-23 English Longitudinal Stu …

19.08.2026journal-article

Bone & Joint Open

Protocol for the ACTIVE trial: a multicentre, open-label, cluster-randomized controlled trial of a quality improvement programme for older adults with hip fracture in resource-limited hospitals in China

Minghui Yang, Tingzhuo Liu, Gang Liu, Ning Tang, Xinyi Zhang, Rebecca Ivers, Yongchen Wang, Maoyi Tian

Aims The primary aim of the Action on Hip Fracture Management Quality Improvement (ACTIVE) trial is to evaluate whether a context-tailored quality improvement programme improves health-related quality of life at 120 days after hospital admission, among adults aged 65 years or older with a hip fracture, in less-resourced hospitals in China. Secondary aims are to compare health-related quality of life at 30 days, complication and morbidity at 30 and 120 days, proportion of patients receiving surgery, proportion of pa …