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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

American Journal of Surgical Pathology

International Society of Urological Pathology Multidisciplinary Expert Consultation Conference on Evaluation of Treatment Effects in Prostate and Bladder Cancer

Michelle R. Downes, Sara E. Wobker, Steven C. Smith, Markus Eckstein, Mahmut Akgul, Dilek E. Baydar, Fadi Brimo, Eva Compérat, Arndt Hartmann, Ashish M. Kamat, Anandi Lobo, Maria R. Raspollini, Ankur R. Sangoi, Shahrokh F. Shariat, Toyonori Tsuzuki, Bas W. G. van Rhijn, Sean R. Williamson, Geert J. L. H. van Leenders, Liang Cheng, Antonio Lopez-Beltran, the Members of ISUP GU Cancer Treatment Effects Consensus Panel

Treatment effects in the urinary bladder are variable and range from localized post-transurethral resection changes to widespread systemic therapy effects. The International Society of Urological Pathology (ISUP) organized a consensus meeting in Vienna, Austria, in September 2025, focused on the evaluation of treatment effects in both the prostate and bladder. Working Group 2 was assigned the topic of the urinary bladder, and a group of pathologists and clinicians was convened. They worked cooperatively to develop …

02.09.2026journal-article

Advances in Skin & Wound Care

Implementing a Nurse-driven Quality Improvement System for Incontinence-associated Dermatitis Prevention in a General Surgery Ward

Hongxia Xu, Yanping Huang, Lili Cheng, Huiyan Wei, Liping Zhu, Liuqun Feng, Ying Wang, Jinli Mao, Hongyang Hu, Hongying Pan

OBJECTIVE: This quality improvement (QI) project evaluated the effectiveness of a structured, nurse-driven incontinence-associated dermatitis (IAD) prevention system in reducing IAD incidence and severity and improving nursing staff knowledge and caregiver adherence in a general surgery ward. METHODS: A pre-post QI project was conducted in the general surgery ward of a tertiary hospital. The intervention included systematic identification of high-risk patients, standardized preventive nursing protocols, nurse train …

02.09.2026journal-article

Biomedicines

Stem Cell-Derived Extracellular Vesicles for the Treatment of Osteoporosis: A Systematic Review of Preclinical Evidence

Yi Yang, Lifen Qiao, Yan Huang, Qin Xia, Hui Xie

Background: Osteoporosis is a prevalent skeletal disorder characterized by reduced bone mass and microarchitectural deterioration, resulting in an increased risk of fractures. Stem cell-derived extracellular vesicles (EVs) have emerged as a promising cell-free therapeutic strategy owing to their inherent advantages, including excellent biocompatibility, low immunogenicity, diverse biological activities, and engineering potential. Despite growing interest in this field, the existing preclinical evidence remains high …

02.09.2026journal-article

The Journal of Applied Engineering and Technologies

Propagation-Aware Sensor Evidence Mapping for Aircraft Engine Health Diagnosis

Camille Laurent, Antoine Moreau, Claire Dubois

Aircraft engines generate continuous multivariate sensor time series from exhaust gas temperature, fuel flow, vibration, rotor speed, oil pressure, compressor pressure ratio, turbine temperature, and control actuator signals. These variables are tightly coupled through thermodynamic, mechanical, and control feedback relationships. A local abnormal change in one component may propagate to multiple downstream sensors, making it difficult to distinguish the initiating fault from secondary responses. This study propose …

02.09.2026journal-article

Bioresources and Bioprocessing

Unveiling the mechanism of metabolites derived from gut microbiota in the treatment of acute kidney injury via network pharmacology and bioinformatics

Weiguo Yao, Jinlin Huo, Kun liu, Pengyu Tao

Abstract Background Acute kidney injury (AKI) affects a considerable proportion of patients that represents a major challenge for clinical treatment. Gut microbiota metabolites have been reported to attenuate acute kidney injury (AKI), yet their underlying mechanisms remain largely elusive. The present study aimed to explore the protective mechanisms of these metabolites against AKI using. Methods The targets of metabolites and AKI were obtained from public databases. The PPI network is utilized to identify the cor …

02.09.2026journal-article

Annals of Surgery

Integrative Muscle-Adipose Score (IMAS)

Frederik Schliephake, Isabella Lurje, Jan Bednarsch, Katharina Dreher, Jude Bitar, Carolin V. Schneider, Deniz Uluk, Zoltan Czigany, Pavel Strnad, Cornelius Engelmann, Ulf P. Neumann, Florian W. Vondran, Johann Pratschke, Robert Öllinger, Frank Tacke, Georg Lurje

Objective: To investigate the potential of integrating muscle and fat compartments into a novel and unified score for outcome prediction in a bicentric European cohort of LT recipients. Background: Body composition (BC) reflects nutritional status and metabolic reserves and influences outcomes after orthotopic liver transplantation (LT). Validated tools for predicting long-term survival after LT remain scarce. Increasing evidence highlights sex-specific disparities in post-transplant outcomes. Study Design: A total …

02.09.2026journal-article

Neuroradiology

Clinical outcome after rescue intracranial stenting: a comparison of the ACCLINO flex and the CREDO heal stenting platforms after failed mechanical thrombectomy

Christoph M. Mooshage, Niclas Schmitt, Fabian Preisner, Tim Hilgenfeld, Kianush Karimian-Jazi, Michael O. Breckwoldt, Daniel Schwarz, Alexander Hubert, Sophia Hohenstatt, Julius M Kernbach, Alexandra Filipov, Damjan Mirkov, Peter A Ringleb, Christian Herweh, Martin Bendszus, Dominik F. Vollherbst, Markus A. Möhlenbruch

Abstract Purpose Mechanical thrombectomy (MT) is the first-line therapy for patients with acute ischemic stroke due to large vessel occlusion; however, despite substantial advances in MT techniques and devices, mechanical recanalization remains unsuccessful in up to 15% of patients. Intracranial rescue stenting represents a promising option to achieve successful recanalization and good clinical outcomes in patients with failed MT. Methods In this retrospective, observational single-center analysis 77 consecutive pa …

02.09.2026journal-article

Review of Communication Research

Application of Computer-Simulation-Based Clinical Case Training for General Practice Clinical Reasoning in Standardized Residency Training: A Digital Health Communication Perspective

Huan Yu, Zhen Qiao, Lina Ma, Peng Li

Clinical reasoning is a core competency in standardized residency training for general practitioners, yet conventional case-based instruction is often constrained by limited clinical exposure, inconsistent case complexity, and insufficient opportunities for repeated decision-making practice. This study explores the application of computer-simulation-based clinical case training to improve clinical reasoning among general practice residents from a digital health communication perspective. A digital simulation enviro …

02.09.2026journal-article

Iranian Journal of Allergy, Asthma and Immunology

Clinical and Inflammatory Benefits of Nebulized Furosemide with Salbutamol–ipratropium in COPD Exacerbations: A Randomized Controlled Trial

Mahdi Behi, Babak Gholamine, Mohammad Reza Masjedi, Alireza Eslaminejad, Esmaeil Idani, Mohsen Sadeghi, Akram Qanavati, Sayed Mehran Marashian, Esmaeil Mortaz, Atefeh Abedini, Mihan Pourabdollah, Bita Pakshad, Saeid Mahmoodian

Exacerbations of chronic obstructive pulmonary disease (COPD) are a leading cause of morbidity, mortality, and healthcare burden. While standard bronchodilator therapy alleviates airway obstruction, its efficacy is often limited. This study evaluated nebulized furosemide, which has bronchodilatory and anti-inflammatory effects, as an adjunct to salbutamol–ipratropium in hospitalized COPD patients. Ninety‑two patients with exacerbated COPD were randomly assigned to two equal groups (46 each). The intervention group …

02.09.2026journal-article

Ophthalmic Plastic & Reconstructive Surgery

Occult Lacrimal Pathology in Young Versus Older Patients With Presumed Primary Acquired Nasolacrimal Duct Obstruction: Implications for Preoperative Imaging

Steffie Arès, Charlotte Lussier, Olivia Serhan, Myriam Belaiche, Evan Kalin-Hajdu

Purpose: Approximately 50% of ASOPRS surgeons consider young age to be an indication for imaging in patients with nasolacrimal duct obstruction. This practice is rooted in the assumption that young age confers a higher risk of clinically occult disease. This study examines whether young age is, in fact, associated with clinically occult lacrimal pathology. Methods: A retrospective multicenter chart review was conducted at the Université de Montréal on consecutive patients with clinically presumed primary acquired n …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Building Research Leadership for Global Health Impact

Anna Kalbarczyk, Meagan Harrison, Yukari C. Manabe, Benjamin H. Chi, Bhakti Hansoti

ABSTRACT. Global health research training programs have traditionally emphasized methodological competencies, yet technical skills alone cannot ensure equitable partnerships, effective crosscultural collaboration, or durable and locally relevant research impact in international settings. The Research Leadership Academy (RLA) was developed to fill this gap. The RLA is a structured leadership curriculum embedded within the NIH Fogarty-funded UJMT LAUNCH global health research fellowship grounded in experiential learn …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

In Skin Biopsies of Localized Cutaneous Leishmaniasis Patients from Ethiopia, Expression of Anti-Inflammatory Cytokines was Greater than that of Proinflammatory Cytokines

Sofia Yimam, Abay Atnafu Ayele, Selfu Girma, Menal Hassen, Bethelehem Nigussie, Esmael Besufikad, Tewodros Tariku Gebresilase, Jemal Alemu, Negash Baye, Tigist Girma, Zewditu Chanyalew, Nega Berhe, Tesfaye Gelanew, Mengistu Legesse, Menberework Chanyalew

ABSTRACT. The immunopathology of cutaneous leishmaniasis (CL) caused by Leishmania aethopica is not well understood. This study aimed to characterize the host’s localized immune response in formalin-fixed paraffin-embedded (FFPE) skin biopsies taken from skin lesions of patients who had developed localized CL due to infection with L. aethiopica . A retrospective cross-sectional study was conducted on 40 FFPE skin biopsy samples collected from 2018 to 2022 in the ALERT hospital, Addis Ababa, Ethiopia. Immunohistoche …

02.09.2026journal-article

Journal of Emergency and Disaster Medicine

Unmanned systems in large-scale combat operations: a scoping review of their impact and integration in prolonged casualty care

Chloé Waters, Attila J. Hertelendy, Fadi Issa, Williams Lopez Vidal, Amalia Voskanyan, Gregory Ciottone

Abstract Background Large-scale combat operations (LSCO) have disrupted prior battlefield healthcare models reliant on rapid evacuation and the “Golden Hour.” In contemporary conflicts, including Ukraine, Gaza, Sudan, and Iran, care is often delivered in highly contested environments with degraded infrastructure and persistent surveillance, where evacuation is frequently delayed or denied. This has necessitated a shift toward prolonged casualty care (PCC). Although unmanned systems (UxS) demonstrate utility in civi …

02.09.2026journal-article

Artefactum - revista de estudos interdisciplinares

COMPATIBILITY OF RICE HUSK AS A CARRIER MEDIUM FOR BACILLUS SP. IN AN ACTIVATED SLUDGE PROTOTYPE FOR DOMESTIC SEWAGE TREATMENT

Carlos Eduardo Saraiva Mauer

Sanitation in Brazil still shows significant gaps in coverage and operational efficiency, which encourages the search for inputs capable of enhancing the performance of wastewater treatment plants. Among these inputs are granular bioremediators, whose formulation relies on food-grade cereals – mainly wheat bran – as the carrier medium for microorganisms, accounting for roughly 70% of the product cost. This article assesses the compatibility of rice husk, an abundant and low-cost agro-industrial residue, as a carrie …

02.09.2026journal-article

Sage Sphere International Journal

Cirugía mínimamente invasiva en cirugía pancreática: una revisión de sus beneficios clínicos

Kevin Jonathan García Intriago, Daiana Stefanny Morán Higuera, Mario Gabriel Salas Martínez, Anthony Paul Vega Romero, Ricky Mauricio Rey Vivanco

Introducción: La cirugía mínimamente invasiva (CMI) ha transformado radicalmente el abordaje terapéutico de las patologías pancreáticas benignas y malignas. La incorporación progresiva de técnicas laparoscópicas y asistidas por robot busca reducir el trauma quirúrgico, optimizar la precisión anatómica y ofrecer potenciales beneficios perioperatorios frente al abordaje abierto convencional. Objetivo: Sintetizar la evidencia científica actual sobre los beneficios clínicos, resultados perioperatorios y efectividad de …

02.09.2026journal-article

Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science

Cross-load robustness evaluation of deep and handcrafted learning frameworks for bearing fault diagnosis

Rohit Mishra, Bhagat Singh, Yogesh Shrivastava

This paper introduces a comprehensive leakage-free methodology for bearing fault diagnosis by three of the most representative feature learning approaches: Raw Signal Convolutional Neural Network (Raw CNN), Fast Fourier Transform (FFT) based hybrid MLP-CNN, and handcrafted statistical descriptor based Multilayer Perceptron (MLP). The vibration data collected from the Case Western Reserve University (CWRU) bearing set for four operating conditions (0, 1, 2, and 3 HP) was used. To eliminate information leakage, all m …

02.09.2026journal-article

Hospital Pharmacy

Pharmaceutical 3D Printing From Personalized Medicine to Super-Compounding Pharmacies: A Narrative Review

Michele Favia, Giulio De Vivo, Paola Cristina Cappelletto, Gabriele Bagaglini

Objectives: This narrative review explores how pharmaceutical 3-dimensional printing (3DP) can transform solid dosage form manufacturing from industrial mass production to truly personalized medicine, particularly for vulnerable cohorts such as pediatric, geriatric, and rare disease patients for whom conventional strengths and dosage forms are often inadequate and prompt unsafe manipulations like tablet splitting. It further aims to critically appraise the main 3DP technologies applicable in pharmacy – fused deposi …

02.09.2026journal-article

World Journal of Surgery

Perioperative Hemoglobin Trajectory and Hemoglobin Decrease in Major Abdominal Surgery

Javier Ripollés‐Melchor, Ane Abad‐Motos, Carlos Jericó, Toby Richards, Ángel Espinosa, Gianluca Pellino, Diana Fernández‐García, Rosalía Navarro‐Pérez, Rachel Budithi, Kenneth J. Macpherson, José A. García‐Erce, POSTVenTT Group

ABSTRACT Background Most studies evaluate perioperative hemoglobin at a single time point despite substantial changes across the perioperative period. We examined whether perioperative hemoglobin trajectory and perioperative hemoglobin decrease were associated with postoperative outcomes after major abdominal surgery. Methods We performed a secondary analysis of the international POSTVenTT cohort, a prospective multicentre observational study of adults undergoing major abdominal surgery. Hemoglobin trajectory was d …

02.09.2026journal-article

Journal of Tropical Medicine and Public Health Solutions

Haematological Responses to Ethanol Extracts of Chia Seed and Tiger Nut in Alloxan-Induced Diabetic Rats

Chinyere S. Nwaka, Andrew C. Nwaka

Diabetes mellitus is often accompanied by disturbances in haematological indices, reflecting the broader metabolic stress of chronic hyperglycaemia. This study evaluated the effect of ethanol extracts of chia seed (Salvia hispanica) and tiger nut (Cyperus esculentus), administered separately and in combination, on haemoglobin (Hb), packed cell volume (PCV), red blood cell (RBC) count, white blood cell (WBC) count, lymphocyte, and neutrophil levels in alloxan-induced diabetic Wistar rats. Sixty-three male rats were …

02.09.2026journal-article

Academy for Practical Oncology

Comparative analysis of clinical and functional results of one-stage and two-stage breast reconstruction after mastectomy in patients with large mammary glands

S. V. Kozlov, O. I. Kaganov, M. V. Tkachev, A. V. Bukin

BACKGROUND : The advancement and refinement of surgical treatment approaches for breast carcinoma facilitate the preservation of a high quality of life in patients following reconstructive procedures, particularly in cases of substantial breast volume and pronounced ptosis. AIM : To compare the immediate and long-term outcomes and quality of life in patients undergoing two-stage versus one-stage reconstruction after skin-sparing mastectomy in breasts exceeding 150 mL in volume. METHODS : A retrospective analysis of …

02.09.2026journal-article

Clinical Spine Surgery

Cervical Paraspinal Muscle Atrophy Is Associated With Internal Carotid Artery Stenosis

Bruno Verna, Ali E. Guven, Marco D. Burkhard, Erika Chiapparelli, Anna-Maria Mielke, Vidushi Tripathi, Thomas Caffard, Artine Arzani, Jiaqi Zhu, Jennifer Shue, John A. Carrino, Andrew A. Sama, Federico P. Girardi, Frank P. Cammisa, Alexander P. Hughes

Study Design: Retrospective cross-sectional study. Objective: The objective of our study is to assess the relationship between carotid artery stenosis (CAS) and muscle morphology. Summary of Background Data: Paraspinal muscle degeneration, marked by fatty infiltration (FI) and reduced functional cross-sectional area (fCSA), contributes to spine instability, chronic pain, and disc degeneration. While abdominal aortic calcification is linked to lumbar muscle atrophy, cervical vascular-muscle associations remain under …

02.09.2026journal-article

Endocrines

Vitamin D Supplementation in Infertile Men: Beyond Pooled Effects—A Critical Meta-Analysis of Heterogeneous Clinical Responses

Dragoș Puia, Marius Ivănuță, Mihaela Corlade-Andrei, Hicham Tory, Adrian-Gabriel Majeru, Bogdan Doroftei, Ramona Ștefăniu, Vlad Cristiana Elena, Cătălin Pricop

Introduction: Male infertility is a complex global health challenge, with emerging evidence suggesting that vitamin D plays a pivotal role in testicular function and spermatogenesis. This systematic review and meta-analysis aimed to evaluate the impact of vitamin D supplementation on semen parameters and reproductive hormones in infertile men. Methods: A comprehensive search of electronic databases (PubMed, Cochrane Library, and Web of Science) was conducted to identify randomized controlled trials (RCTs) investiga …

02.09.2026journal-article

Scientific Reports

Supportive care needs among patients with breast and cervical cancer at a tertiary cancer treatment center in ethiopia: a cross-sectional study

Bedilu Deribe Derese, Eva Johanna Kantelhardt, Thomas Frese, Betty Ferrell, Muluken Gizaw, Sefonias Getachew, Abigiya Wondimagegnehu, Adamu Addissie, Eric Sven Kroeber, Lesley Taylor, Susanne Unverzagt

Abstract The rising incidence of cancer diagnoses alongside improving survival rates in low- and middle-income countries (LMICs) has substantially increased the demand for comprehensive supportive care. This study aimed to assess the supportive care needs of patients diagnosed with breast or cervical cancer at Hawassa University Comprehensive Specialized Hospital Cancer Treatment Center, Ethiopia. A hospital-based cross-sectional study was conducted among 349 patients with breast or cervical cancer between December …