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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Veterinary Sciences

Hemodynamic Effects of Intravenous Ephedrine Administration During General Anesthesia for Radiation Therapy in Cats

Daichi Seki, Seijirow Goya, Kenji Teshima, Yoshiki Yamaya

Ephedrine is used as a vasopressor in cats, but the hemodynamic effects of intravenous (IV) administration have not been characterized. This study evaluated the hemodynamic effects of IV ephedrine in 10 cats that developed hypotension during anesthesia. Cats received either saline (SE) or atropine (AE) before ephedrine for hypotension (mean arterial pressure < 60 mmHg). Hemodynamic variables were analyzed using a linear mixed-effects model. No significant differences were observed between groups in the response rat …

27.08.2026journal-article

Environmental Toxicology

Integrated Alpha–Gamma Radiation Exposure From Natural Radionuclides in Cement and Gypsum Production: Implications for Occupational Lung Cancer Risk

Adil M. Hussien, Kardo O. Mamand, Hiwa M. Qadir, Berun N. Ghafoor, Goran H. Mohammad

ABSTRACT Natural radionuclides in cement and gypsum production materials pose significant risks of occupational radiation exposure that are not well documented in Iraqi Kurdistan. This study quantifies alpha and gamma radiation levels from naturally occurring radioactive materials, specifically 222 Rn, 238 U, 232 Th, and 40 K, in cement and gypsum samples from regional production facilities. Radionuclide activity concentrations were measured using alpha counting techniques and gamma spectrometry. The air concentrat …

27.08.2026journal-article

British Journal of Occupational Therapy

Integrating sensory-oriented electrical stimulation with occupation-based, client-centered occupational therapy to support upper limb use after degenerative cervical myelopathy: A case report

Mikari Toki, Takuya Hirose, Sho Maruyama, Hiroki Himeda, Kanta Ohno

Introduction: Degenerative cervical myelopathy often results in persistent upper limb sensory impairment after surgery, limiting functional hand use despite motor recovery. This case report aimed to describe an occupational therapy intervention integrating sensory-oriented electrical stimulation with occupation-based, client-centered practice to support upper limb use after degenerative cervical myelopathy surgery. Method: This case report describes a woman in her seventies with postoperative degenerative cervical …

27.08.2026journal-article

Physiotherapy Research International

Shared Decision‐Making and Patient Enablement in Outpatient Rehabilitation: An Observational Study

Naoto Iwasawa, Shota Hori, Hitoshi Fujita, Takuya Yamada, Hirono Ishikawa

ABSTRACT Objectives To examine the association between shared decision‐making (SDM) and patient enablement in outpatient rehabilitation consultations. Methods In this observational cross‐sectional study, 158 patients attending outpatient rehabilitation at four facilities in Japan were assessed, of whom 93 were included in the final analyses. Sociodemographic data, disease severity (modified Rankin Scale), treatment expectations, control preferences, and health literacy were collected via self‐administered questionn …

27.08.2026journal-article

Frontiers in Pediatrics

Risk factors for abnormal bone mineral density in Duchenne muscular dystrophy and the association of regular rehabilitation with bone health

Yi Chen, Shaowei Dong, Meihuan Huang, Guixiang Liu, Turong Chen, Chunming Zhou, Mingsheng Zhang

Background We investigated the prevalence and risk factors of abnormal bone mineral density (BMD) in Duchenne muscular dystrophy (DMD) and explored the potential association of regular rehabilitation with BMD. Methods A cross-sectional study including 215 boys with DMD was conducted. Multivariate logistic regression was used to identify independent predictors, and mediation analysis was performed to explore the pathway linking rehabilitation and BMD. Results Abnormal BMD was found in 62 patients (28.8%). Age was th …

27.08.2026journal-article

Global Wound Care Journal

Experimental assessment of the effectiveness of electromagnetic therapy in purulent and burn wound healing process

Vishrabdha Chandrakant Margaj et al

Introduction: Wound infection is a significant healthcare problem, and electromagnetic therapy (EMT) is a promising tool to reduce bacterial load and promote wound healing. Aim: This study aimed to provide an objective assessment of efficacy of EMT in healing of purulent and burn wounds in experimental animals. Methods: Our prospective, non-randomised study enrolled 28 non-pedigree rabbits aged 2-3 months, divided into two groups. Wounds of the experimental group (n=14) were treated with local EMT using a TOR elect …

27.08.2026journal-article

Physiotherapy Quarterly

The effect of supervised exercise intervention program on the quality of life, disability, anxiety, and depression in post-lumbar discectomy patients

Neveen Yaseen, Ahmed A. Najim, Adnan M.M. Naser, Mosab Aldabbas

Introduction Lumbar discectomy is commonly performed to relieve nerve root compression, but many patients experience ongoing pain and disability post-surgery. Supervised physiotherapy may improve these outcomes, though its benefits remain underexplored. This study aimed to evaluate the impact of a physiotherapy program on quality of life, pain, disability, anxiety, and depression after lumbar discectomy. Methods A Quasi-Experimental Study was conducted involving 34 patients (17 males, 17 females; mean age 48.38 ± 6 …

27.08.2026journal-article

BMC Oral Health

Oral findings and antiresorptive therapy exposure duration in postmenopausal women with osteoporosis: a cross-sectional cohort study

Safiyye Süslü, Håvard J Haugen, Tormod Bjartveit Krüger, Bente B. Herlofson, Janne Elin Reseland, Erik Fink Eriksen

Abstract Background Oral findings are common among older adults, but it is unclear whether they vary with the duration of antiresorptive therapy (ART) exposure or relate to the severity of osteoporosis in postmenopausal women. Methods In this cross-sectional cohort ( n = 129), postmenopausal women undergoing osteoporosis assessment/follow-up were stratified by ART exposure duration: no current ART control (G1, n = 50), short ART (G2, 3–5 years; n = 39), and long ART (G3, > 5 years; n = 40). The prespecified primary …

27.08.2026journal-article

Journal of International Research in Medical and Pharmaceutical Sciences

Nanoparticle-Mediated Targeting of the Arthritic Joint: A Critical Narrative Review of Drug Delivery and Molecular Therapy

Jharna Sahu, Chandrika Ahirwal

Nanoparticle-based delivery is being developed to concentrate anti-inflammatory, disease-modifying and molecular therapeutics within arthritic joints while limiting systemic exposure. Yet “joint targeting” encompasses several distinct problems: vascular access to inflamed synovium, persistence after intra-articular administration, penetration through dense avascular cartilage, cell-selective uptake and release of an active payload at the intended intracellular or extracellular site. This critical narrative review e …

27.08.2026journal-article

SVOA Medical Research

Uncontrolled Levothyroxine Replacement Therapy in Primary Care: Frequency and Associated Biochemical and Hematological Findings

Mesut Sekeroglu

Hypothyroidism is one of the most common endocrine disorders worldwide. Despite well-established levothyroxine (LT4) replacement therapy, achieving biochemical euthyroidism remains challenging. This study aimed to determine the frequency of uncontrolled LT4 replacement therapy and its associated biochemical and hematological findings in adults with primary hypothyroidism followed in primary care. This retrospective study included 157 adults with primary hypothyroidism receiving LT4 replacement therapy who attended …

27.08.2026journal-article

Lymphatics

Draining the Brain: A Novel Noninvasive Lymphatic Therapy for Parkinson’s Disease

Yazan Mahafza, Winnie Pao, Angela Bialorucki, Heidi Simon, Wei F. Chen

The discovery of the glymphatic system and meningeal lymphatic vessels established that the brain possesses an organized lymphatic clearance network that drains to the deep cervical lymphatics. Disruption of this system has been suggested to contribute to the accumulation of pathogenic proteins implicated in neurodegeneration. Cervical lymphatic reconstruction has been associated with some neurological benefit in Alzheimer’s and Parkinson’s disease, and preclinical work has demonstrated that noninvasive manipulatio …

27.08.2026journal-article

International Journal of Biology and Life Sciences

Ankle Lateral Collateral Ligament Injury Rehabilitation: Current Issues and Future Trends

Xiaoya Ma

Lateral ankle ligament injuries are one of the most prevalent musculoskeletal injuries accounting for 40 percent of all sports-related trauma. Inadequate rehabilitation may result in a high incidence of re-injury and chronic ankle instability, which causes a lasting effects on mobility and quality of life. This paper discusses the anatomy of the lateral ankle ligament tears, existing rehabilitation evaluation techniques and management plans, and some of the obstacles and opportunities that define future clinical tr …

27.08.2026journal-article

Neuro-Oncology

29 Repetitive Transcranial Magnetic Stimulation (rTMS) for Motor Rehabilitation in Neuro-Oncology: the impact of the Orpington Prognostic Score (OPS)

Katie Mirocha, Amy Jones, Jose Lavrador, Keyoumars Ashkan, Ranj Bhangoo, Francesco Vergani

Abstract Introduction rTMS is well-evidenced in the stroke population. Its therapeutic use is increasing in post-operative neuro-oncology patients. Functional outcomes using the OPS, a prognostic indicator for onwards rehabilitation needs, are yet to be explored. This is an exploratory study assessing the feasibility of the OPS to monitor functional outcomes and guide rehabilitation streams in post-operative neuro-oncology patients receiving the rTMS motor rehabilitation protocol for new motor deficit. Method Over …

27.08.2026journal-article

Discourse & Communication

Prosodic cues and pragmatic inference in populist political speech: A case study of Donald Trump’s rallies

Pablo Agustín Artero Abellan

This article examines how selected prosodic cues in Donald Trump’s campaign rallies guide audience inference in populist political performance. Rather than offering a corpus-wide account, it presents a discourse-pragmatic case study of four focal extracts drawn from a larger dataset of 10 campaign rallies from the 2016 and 2020 U.S. presidential elections. Combining time-aligned transcription with Praat-based inspection of F0, intensity, duration, and pause structure, the study analyzes how local prosodic patternin …

27.08.2026journal-article

Journal of Innovative Healthcare Practices

Recommended Mirror Therapy Protocol Based on Supportive Existing Research in CVA Rehabilitation: A Systematic Review

Terrell Kane, Blair Carsone

The purpose of this systematic review was to use existing research to extract a recommended protocol for mirror therapy during CVA rehabilitation. Articles included were published within the last 5 years, in English, had accessible full text versions of the articles, and involved an adult population of individuals 18 years and older. Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were used by two certified occupational therapists to identify and screen studies to be included i …

27.08.2026journal-article

Arthroscopy, Sports Medicine, and Rehabilitation

Availability and Pricing of Orthobiologic Knee Injections Vary by Practice Type but Not by Community Socioeconomic Vulnerability in Suburban New York

Tracy M. Tauro, Benjamin Hershfeld, Katharine Chen, Ran Lampert, Adam D. Bitterman, Randy M. Cohn, Nicholas A. Sgaglione

Purpose To assess the availability, price transparency, and pricing of platelet‐rich plasma (PRP), bone marrow aspirate concentration, and stem cell injections for knee osteoarthritis (OA) among orthopaedic sports medicine (OSM) practices and alternative clinics in suburban New York and to evaluate the impact of the economic status of a population on the availability and pricing of biologic injections. Methods Between July and September 2025, OSM practices and alternative clinics offering PRP, bone marrow aspirate …

27.08.2026journal-article

International Journal of Molecular Sciences

Repurposing Disulfiram for Cancer Therapy: Mechanistic Insights and Translational Challenges

Anna Bilska-Wilkosz, Magdalena Górny, Małgorzata Iciek

Disulfiram (DSF), long used as an aversive agent in alcohol dependence therapy, has recently regained attention as a promising candidate for oncological drug repurposing. After administration, DSF is rapidly reduced to diethyldithiocarbamate (DDC), which, in the presence of Cu2+, forms the complex Cu(DDC)2. This compound acts as a strong inducer of oxidative stress, an inhibitor of the ubiquitin–proteasome system, and a suppressor of endogenous hydrogen sulfide (H2S) synthesis. DSF also modifies protein and non-pro …

27.08.2026journal-article

Addiction Science Reviews

A Systematic Review on the Effectiveness of Cognitive Behavioral Therapy in Substance Use Disorders

Erva Ceren Gülsatar, Fahriye Balkır

Substance Use Disorder (SUD) is a multidimensional clinical condition characterized by impaired control over substance use and significant deterioration in psychological, physical, and social functioning. The aim of this systematic review was to evaluate the effectiveness of Cognitive Behavioral Therapy (CBT) in the treatment of substance use disorders based on current evidence. The review was conducted in accordance with the PRISMA 2020 guidelines. Studies published between January 2010 and June 2026 were identifi …

27.08.2026journal-article

Cellular Oncology

Epigenetic memory of epithelial–mesenchymal transition: linking transient plasticity to metastasis, therapy resistance, and immune evasion

Dominika Denisz, Magdalena Fabian, Jan Olszewski, Karolina Bajdak-Rusinek

Abstract Epithelial–mesenchymal transition (EMT) is increasingly recognized as a dynamic, plastic process that equips tumor cells with invasive capacity, stress tolerance, stem-like features, and adaptability, contributing to metastasis, therapeutic failure, and immune escape. Accumulating evidence indicates that these effects can outlast the inducing signal: tumor cells may retain molecular and functional traces of prior EMT exposure, biasing future cell-state behavior. This Review terms this phenomenon EMT memory …

27.08.2026journal-article

Journal of Occupational & Environmental Medicine

The Effectiveness of Ergonomic Training and Chiropractic Treatment in Industrial Workers with Nonspecific Chronic Neck Pain: A Randomized Controlled Trial

Deniz Balikçi, Beyzanur Dikmen Hoşbaş, Ömer Şevgin

OBJECTIVE: To evaluate whether adding chiropractic treatment to ergonomic training improves pain, function, and sleep in industrial workers with chronic nonspecific neck pain. METHODS: Forty-five male industrial workers were randomized (15 per group) to ergonomic training plus chiropractic treatment (CTG), plus sham manipulation (SMTG), or alone (CG) for four weeks. Pain (VAS), biopsychosocial impact (BNQ), disability (NDI), and sleep quality (PSQI) were assessed before and after. The group × time interaction was t …

27.08.2026journal-article

Perspectives of the ASHA Special Interest Groups

Breathing Retraining and Laryngeal Control in Exercise-Induced Laryngeal Obstruction and Breathing Pattern Dysfunction: A Practical Therapy Model for Clinicians

Amrita Bonthu, Claudio F. Milstein

Objective: Exercise-induced laryngeal obstruction (EILO) and breathing pattern dysfunction (BPD) are common, yet frequently misdiagnosed, contributors to exertional dyspnea, especially in adolescent and young adult athletes. Despite increasing recognition of behavioral interventions as first-line therapy, there is a lack of simple, accessible, and reproducible protocols in clinical settings. This clinical focus article describes a practical, clinician-friendly therapy model that integrates laryngeal control, respir …

27.08.2026journal-article

Cellulose

Bioactive silver(I) complex delivered via bacterial cellulose and Zeolitic imidazolate framework-8 composites for skin cancer therapy

Silmara C. Lazarini Frajácomo, Augusto Henrique Piva, Hernane da Silva Barud, Eliane Trovatti, Tamires de Souza Nossa, Bernardo Castro-Dominguez, Regina Celia Galvão Frem, Bruna C. Lustri, Douglas H. Nakahata, Pedro P. Corbi, Wilton R. Lustri

Abstract Topical antimicrobial strategies that combine targeted drug delivery with selective cytotoxicity are critically needed for treating infected skin lesions, especially those complicated by multidrug-resistant bacteria. Here, we report the synthesis, characterization, and evaluation of a silver(I) complex with the sulfonamide probenecid (Ag–PROB) and its integration into a bacterial cellulose (BC) based composite with zeolitic imidazolate framework-8 (ZIF-8) for controlled release applications. We developed t …

27.08.2026journal-article

Clinical Case Reports

Digital Implant Rehabilitation in Multiple Idiopathic Root Resorption: A Case Report

Shoresh Afnan, Thomas Alexander Cursiter Hunter, Kåre Jan Attramadal, Jashan Singh Kamboj

ABSTRACT Multiple idiopathic root resorptions (MIRs) represent a rare condition with uncertain etiology and limited treatment options, and they may compromise the prognosis of affected teeth. A digitally guided interdisciplinary approach combining cone‐beam computed tomography (CBCT) diagnostics, virtual implant planning, and immediate implant‐supported restoration can provide predictable, functional, and esthetic outcomes in complex cases.

27.08.2026journal-article

Nursing Edição Brasileira

Eficácia da Terapia de Privação de Sono (wake Therapy) Como Potencializador de Antidepressivos

Carliene Sodré Magno França, Carolina Bilego Bello, Lara Rodrigues Lima Ribeiro

O transtorno depressivo maior representa um grave problema de saúde pública, sendo caracterizado por alta prevalência e limitações importantes no tratamento farmacológico convencional, notadamente a latência na resposta terapêutica. A terapia de privação de sono, também chamada de wake therapy, surge como uma estratégia cronobiológica de ação rápida para a remissão de sintomas depressivos. Este estudo teve como objetivo realizar uma revisão sistemática da literatura sobre a eficácia da privação de sono como interve …