Clinical Dermatology Review
Comparative Study to Assess the Safety and Efficacy of Topical Pilocarpine versus Topical Triamcinolone in the Treatment of Oral Pemphigus Vulgaris
Abstract Background: Oral mucosa is typically the most frequent site of involvement in pemphigus vulgaris (PV). Currently, the mainstay in the treatment of oral erosions is topical corticosteroid. Topical pilocarpine has been tried in oral PV, based on the cholinomimetic property of pilocarpine, which is known to block the process of blister formation. Objectives: We aimed (1) to study the healing effect of pilocarpine 2% paste in oral PV and (2) to compare the efficacy of topical pilocarpine versus topical triamci …