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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
25.08.2026journal-article

JAMA Network Open

Age at Menopause and Brain Atrophy Among Older Women

M. Pia Campagna, Julie A. Schneider, Lisa L. Barnes, Konstantinos Arfanakis, Galit Levi Dunietz, David A. Bennett, Riley M. Bove

Importance Earlier menopause has been linked to increased cognitive decline, but longitudinal data regarding corresponding volumetric brain changes are scarce, and the lasting associations of menopause timing on brain atrophy rates that accompany cognitive decline in women remain unknown. Objective To evaluate whether menopause age is associated with cognitive decline, Alzheimer disease (AD) onset, and brain volume trajectories in older women and whether this differs by menopause type. Design, Setting, and Particip …

25.08.2026journal-article

Journal of Fashion Marketing and Management: An International Journal

A synthesized hierarchy of functional and symbolic product attributes for activewear design for active-aging women

Kristen Morris, Pamela Norum, Hali Ipaye

Purpose This study examines the product attributes that influence activewear satisfaction among active-aging women (AAW), defined as women aged 50 and older who regularly engage in physical activity and pursue wellness-oriented lifestyles. The objective was to identify essential, expected, unexpected and potential product attributes to inform age-inclusive product development, segmentation strategies and brand positioning in the activewear market. Design/methodology/approach A qualitative research design was employ …

25.08.2026journal-article

PLOS Mental Health

Mapping mental health and psychosocial support service availability for adolescents and young people living with HIV in Lusaka and Shibuyunji districts, Zambia: Alignment with ART program burden (September 2024)

Carlos Muleya, Rosemary N. Likwa, Peter J. Chipimo, Jacqueline J. Folotiya, Ngosa Mwiya, Lweendo Mapiki, Asarf Sibuchi, Godfrey Chulu, Caitlin Baumhart, Cassidy W. Claassen, Naeem Dalal, Loyd B. Mulenga

Adolescents and young people living with HIV (AYPLHIV) experience substantial mental health and psychosocial challenges, yet information on youth-responsive service availability is often limited for routine planning. We mapped mental health and psychosocial support services in Lusaka and Shibuyunji districts of Zambia and assessed alignment with AYPLHIV antiretroviral therapy (ART) program burden using treatment current (TX-CURR) ages 15–24 data. We conducted a cross-sectional mapping survey (10–21 February 2025) o …

25.08.2026journal-article

International Journal of Social Economics

The contribution of older adults to the household economy: evidence from the Indonesia national socioeconomic survey

Titik Munawaroh, Sukamdi Sukamdi, Abdur Rofi

Purpose The study provides empirical evidence of older adults' economic contributions, broadening understanding of aging and complementing demographic dependency perspectives. Design/methodology/approach The study measured the economic contribution of older adults in two ways: by analyzing their share of total household working hours and income, using data from the 2020 National Socioeconomic Survey in Indonesia (SUSENAS). Working hours for both older and non-older adults were estimated using the Tobit model, while …

24.08.2026journal-article

Journal of Medical Microbiology

Biofilm sensitization to break Staphylococcus aureus tolerance to cold atmospheric plasma therapy

Abdullah Baz, Jontana Allkja, Muhanna Alshehri, Yao He, Zainab Bilal, Eve Hughes, Olivia Sealy, Craig Williams, Karen Faulds, Gordon Ramage, Jason L. Brown

Introduction. Biofilm-associated infections present a major therapeutic challenge due to their intrinsic tolerance to conventional antimicrobials. Cold atmospheric plasma (CAP) has shown promise as a non-antibiotic antimicrobial modality; however, some bacteria including Staphylococcus aureus can exhibit tolerance to plasma exposure. Gap Statement. Strategies that sensitize CAP-tolerant biofilms to plasma treatment may improve CAP efficacy, but suitable adjunctive compounds and mechanisms remain poorly defined. Aim …

24.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

THE RIGHT OF PEOPLE WITH DISABILITIES TO HIGHER EDUCATION: CREATING UNIVERSAL, BARRIER-FREE UNIVERSITY ENVIRONMENTS

Niellington José Alves, Leandro de Assis Nascimento dos Santos, Érica de Vasconcelos Balbino Alvarenga, Gutemberg Gomes Silva, Patrícia Regina Oliveira da Silva, Diana Cristina Ferreira Souza

Access to higher education for people with disabilities is a central issue in building an inclusive society, since universities must ensure equal opportunities and eliminate physical, pedagogical, and attitudinal barriers. Inclusive education, in this context, involves transforming academic spaces into universal environments capable of guaranteeing the full participation of all students. The overall objective of this study is to analyze the right of people with disabilities to higher education, emphasizing the need …

24.08.2026journal-article

PeerJ

Feasibility and preliminary effects of a culturally adapted short message service intervention for non-communicable disease prevention in older adults: a pilot study

Nour Amin Elsahoryi, Fadia Milhem

Background Among low- and middle-income countries, noncommunicable diseases (NCDs) are a significant health burden among the elderly. Mobile health interventions provide resource-constrained health education that is scalable. Aims Determine the viability, acceptability, and preliminary effects of culturally adapted Short Message Service (SMS)-based nutrition and lifestyle change on the knowledge, attitudes, and practices (KAP) of older adults in Jordan towards prevention of noncommunicable diseases (NCDs). Method a …

24.08.2026journal-article

Theoretical and Natural Science

Research Progress on the Mediating Role of Body Fat Percentage and Precision Prevention Strategies in Community Dietary Interventions for Geriatric Diabetes

Wenbo Luo

As the population ages, the challenge of preventing and managing diabetes among older adults has become increasingly severe. Traditional screening based on Body Mass Index (BMI) often fails to identify high-risk individuals with "hidden obesity." Through a literature review, this paper systematically explores the intrinsic connections and underlying mechanisms linking community-based dietary interventions, the optimization of body fat percentage, and precision prevention strategies for geriatric diabetes. Research …

24.08.2026journal-article

Fluids and Barriers of the CNS

Comparison of blood-brain barrier water exchange rate in young and older adults with diffusion-weighted and multi-echo arterial spin labeling MRI

Yufei D. Zhu, Anjan Bhattarai, Barah Albuhwailah, Xingfeng Shao, Jan Petr, Klaus Eickel, Matthias Günther, Danny J. J. Wang, Audrey P. Fan

Abstract Background Water exchange rate (Kw) across the blood-brain barrier (BBB) has emerged as a candidate biomarker for assessing aging and neurological disease. This work sought to compare the diffusion-weighted (DW) and multi-echo (ME) arterial spin labeling (ASL) MRI sequences that assess Kw across the BBB in a young and an older healthy cohort to examine Kw changes in different brain regions associated with age group. Methods 12 young healthy (21–30 years, 26 ± 3 years, 8 female) and 18 older healthy (66–84 …

24.08.2026journal-article

Journal of Hospice & Palliative Nursing

A Dual-Component Nurse Practitioner Intervention to Improve Symptom Management for Caregivers of Persons Living With Dementia

Veerawat Phongtankuel, Mary Ballin, Jerad Moxley, Taeyoung Park, Micah Denzel Toliver, Giancarlo Chuquitarco, Sara J. Czaja, Ronald D. Adelman, Vanessa Liao, M.C. Reid

The number of patients living with dementia (PLWD) has steadily increased, making it the fifth leading cause of death among adults. While hospice care is standard for end-of-life symptom management, predicting 6-month survival is challenging, leaving many who could benefit ineligible. The study team conducted a single-armed pilot study implementing a nurse-practitioner-led telehealth program for caregivers at an outpatient clinic, focusing on symptom management for PLWD. The study team recruited 15 caregivers with …

24.08.2026journal-article

International Journal of Environmental Research and Public Health

Beyond Diagnosis: Structural Stigma, Trauma, and Mental Health Among People Living with HIV in Tunisia: A Narrative Review

Hatem Laroussi, Mourad Elghali, Wafa Marrakchi, Intissar Souli, Asma Ben Hassine, Amira Abassi, Foued Trabelsi, Hanen Gundogdu

HIV-related stigma constitutes a critical structural determinant that adversely affects mental health and treatment outcomes among people living with HIV (PLWH) in Tunisia. Rooted in cultural conservatism, legal criminalization, and institutional discrimination, this stigma engenders social exclusion, the systematic removal of individuals from community participation. It further fosters internalized shame, precipitating depression, anxiety, and treatment non-adherence. Evidence was synthesized from English- and Fre …

24.08.2026journal-article

Frontiers in Aging

Repair and regeneration across the lifespan: an ontogenetic perspective

Hugo A. Barrera-Saldaña, Luis E. Fernández-Garza, Fernando Guillen-Silva, Oscar R. Fajardo-Ramirez, Rafael Francisco Iñigo Pavlovich, Fermín Valenzuela Gómez-Gallardo, David E. Rodriguez-Fuentes, Alexia Y. Avila-Villalobos, Silvia A. Barrera-Barrera, Rodrigo A. Somoza

The capacity for tissue repair and regeneration undergoes a profound and progressive decline across the human lifespan, representing a fundamental driver of aging and chronic disease. This review establishes a comprehensive ontogenetic framework by mapping the continuous biological transition from the flawless, scarless regenerative plasticity of embryonic development to the irreversible fibrotic scarring and organ failure characteristic of senescence. We synthesize the hierarchical collapse of reparative networks …

24.08.2026journal-article

Journal of Intellectual Disability Research

Parent/Caregiver Perspectives on the Healthcare Decision‐Making Involvement of Young People With Intellectual Disability: A Qualitative Study

Jessica Keeley, Zhenmei Yeap, Thomas Nevill, Rachel Skoss, Aasta Abbott, Sandra Thompson, Sophie Haywood, Rachel Collins, Katherine Langdon, Jenny Downs

ABSTRACT Background Young people with intellectual disability often have complex healthcare needs. Parent/caregivers can enhance their child's involvement in healthcare decision‐making to improve treatment adherence and health outcomes. Healthcare decision‐making is embedded within health literacy skillsets, and for people with intellectual disability additional time and assistance are needed to ensure preferences are included. This study aims to explore parent/caregiver perspectives on the different ways that youn …

24.08.2026journal-article

Investigación e Innovación: Revista Científica de Enfermería

Diabetes Mellitus 2 como factor de riesgo en el desarrollo del Alzheimer en adultos mayores:

Zenaida Leandra Mendive García, Tania de la Caridad García Castellanos, Areli Nicolás Mejía, Caridad Dandicourt-Thomas

La Enfermedad de Alzheimer se considera la principal causa de demencia en los adultos mayores, cursa con un deterioro de las funciones cognitivas, y se asocia a la acumulación de proteína β-amiloide y tau hiperfosforilada en el cerebro. La Diabetes mellitus tipo 2 se considera como un posible factor de riesgo para su desarrollo. Objetivo: sistematizar la evidencia científica sobre la Diabetes Mellitus tipo 2 como factor de riesgo para el desarrollo de la enfermedad de Alzheimer en adultos mayores. Materiales y méto …

24.08.2026journal-article

Frontiers in Cardiovascular Medicine

Nonlinear association between remnant cholesterol inflammation index and incident stroke among middle-aged and older adults with hypertension: a CHARLS cohort study

Siyi Jiang, Ying Cui, Lijun Song, Li Li, Min Li

Background The remnant cholesterol inflammation index (RCII) combines remnant cholesterol (RC) and high-sensitivity C-reactive protein (hs-CRP), two markers that may reflect residual lipid-related and inflammatory vascular burden. We examined whether baseline RCII was associated with incident stroke among hypertensive middle-aged and older adults and whether this association was nonlinear. Methods We analyzed 3,823 stroke-free hypertensive participants aged 45 years or older from the China Health and Retirement Lon …

24.08.2026journal-article

Revista de Geopolítica

NUTRIÇÃO NO ENVELHECIMENTO: A INFLUÊNCIA DAS PRÁTICAS ALIMENTARES NO PROCESSO DE SENESCÊNCIA

Greice Kelly Costa De Sena, Ranielle Barbosa Saraiva, Beatriz Paiva Rocha, Luisa Camila Rodrigues Gomes, Valéria Silva De Lima, Laíze Moreira De França, Rosiane Oliveira De Sousa, Gleiciane Moreira De Lima, Francisca Karusa Carvalho Barbosa, Ana Luiza de Rezende Ferreira Mendes

A alimentação saudável é fundamental para a promoção, manutenção e recuperação da saúde da população idosa. As alterações decorrentes da senescência podem ser significativamente minimizadas por meio da ingestão adequada de nutrientes que contribuem para o bom funcionamento do organismo. Dessa forma, o objetivo do estudo é analisar os efeitos das práticas alimentares e seus impactos na saúde da população idosa, destacando a importância da intervenção nutricional na promoção do envelhecimento saudável. Trata-se de um …

24.08.2026journal-article

The Journal of Physiology

Musculoskeletal and physiological responses to vortex wave stimulation in older adults

Alexander Waddell, Marie Korzepa, Archie E. Belfield, Ben Fry, Rickson C Mesquita, David Smith, Jonathan Quinlan, Leigh Breen

Abstract Reductions in musculoskeletal mass and function can occur with ageing and disuse. While resistance exercise training is known to minimise these detriments, it is not always feasible. Vortex wave stimulation (VWS) may mitigate skeletal muscle decline in such scenarios. The aim of the present study was to explore the acute physiological and metabolic effects of VWS in healthy older adults. Fourteen participants consumed deuterium oxide (D 2 O) stable oral isotope tracer for 7 days. Serial skeletal muscle bio …

24.08.2026journal-article

Infectious Disease Reports

Tricuspid Valve Infective Endocarditis in People Who Inject Drugs: A Single-Center Retrospective Observational Study of Percutaneous Mechanical Aspiration and a Surgical Approach

Lauren Bernard, Juliana S. Sherchan, Nazary Nebeluk, David Zapata, Murtaza Dawood, Douglas Anderson, Ramon A. Riojas, Shivakumar Narayanan

Background: People who inject drugs (PWID) comprise the majority of patients with native tricuspid valve (TV) infective endocarditis (IE). Many patients require surgical repair or replacement of their TV, but some may be deemed ineligible for surgical management due to high operative risk or patient preference. Vacuum-assisted percutaneous mechanical aspiration (PMA) has emerged as a potential alternative to surgical management in this population. The objective of this study was to describe real-world patient chara …

24.08.2026journal-article

Alzheimer's & Dementia: Behavior & Socioeconomics of Aging

Technology‐enabled educational interventions for dementia prevention: A global scoping review with a low resource settings lens

Rhedeya Nury Nodi, Emma Lea, Amy Coates, Mohammad Shoaib Hamrah, James Clement Vickers, Hannah Fair, Eddy Roccati

Abstract Dementia is rising globally, especially in low‐ and middle‐income countries (LMICs) and technology‐enabled education and related tools are potential strategies to address prevention. We synthesized the literature on technology‐enabled dementia prevention education programs worldwide with a focus on LMICs. PubMed, Scopus, Web of Science, PsycINFO, and Google Scholar were searched for primary dementia prevention studies among cognitively healthy adults. Descriptive findings were summarized. Across 37 article …

24.08.2026journal-article

International Journal of Molecular Sciences

Ginsenoside Re Attenuates D-Galactose-Induced Aging-like Oxidative Stress in Cultured Bovine Oocytes via Activation of the SIRT1/Nrf2 Signaling Pathway

Seo-Young Hyeon, Chalani Dilshani Perera, Seung-Eun Lee, Ji-Hyo Kim, Sanghwa Yoon, Yang Jae Kang, Song Park, Muhammad Idrees, Il-Keun Kong

Maternal aging is associated with increased oxidative stress and decreased mitochondrial function, which deteriorate oocyte quality. Ginsenoside Re (GRe), an antioxidant derived from Panax ginseng, has been reported to alleviate cellular damage and extend healthy lifespan. In this study, we investigated the protective effects of GRe on in vitro-matured bovine oocytes and elucidated the underlying mechanisms. Oocyte aging-like oxidative stress conditions were induced by adding 20 mg/mL D-galactose (D-gal) to the in …

24.08.2026journal-article

Surabaya Physical Medicine and Rehabilitation Journal

Effects of a Community-Based Multicomponent Exercise Program on Frailty, Mobility, Strength, and Balance Among Older Adults in East Lombok

Lalu Suprawesta, Indri Susilawati, Ni Ketut Dewita Putri, Siti Ainun Ma'rufa

Background: Frailty is a common geriatric syndrome that increases vulnerability to falls, disability, hospitalization, and loss of independence, particularly among older adults living in rural and low-resource settings. Preventive strategies that are feasible, community-oriented, and clinically relevant are essential to support healthy aging. Aim(s) (including purpose setting): This study aimed to evaluate the effects of a community-based multicomponent therapeutic exercise model on frailty status and functional pe …

24.08.2026journal-article

Frontiers in Aging Neuroscience

Target-level convergence of directional prefrontal connectivity across Alzheimer’s disease stages: an fNIRS study

Nida Mateen, Rana Muhammad Kaleem Ullah, Jisoo Baik, Keum-Shik Hong, Min-Kyoung Kang, Chang-Seok Kim, Yong-Il Shin

Background Alzheimer’s disease (AD) is increasingly recognized as involving network-level dysfunction rather than isolated regional impairment. Although functional and effective connectivity have been studied in dementia, the reorganization of directional information flow within prefrontal networks remains incompletely characterized, particularly with functional near-infrared spectroscopy (fNIRS). Objective This study investigated whether target-level convergence of directional effective connectivity within the pre …

24.08.2026journal-article

PLOS One

Tanshinone IIA attenuates cognitive impairment in vascular dementia rats by modulating copper homeostasis via the SLC31A1/FDX1 axis

Hongxiao Lv, Xinyu Yang, Yutong Liu, Junwei Zhou, Wentao Yu

Background Tanshinone IIA (TSA) is the core liposoluble active component of Salvia miltiorrhiza , a traditional Chinese medicine, and exhibits multiple pharmacological activities including anti-inflammation, anti-oxidation, anti-apoptosis and mitochondrial function improvement. Studies have confirmed that TSA can ameliorate cognitive function in rats with vascular dementia (VaD) by alleviating cerebral ischemic injury, inhibiting neuroinflammation, protecting the blood-brain barrier and other pathways. However, it …

24.08.2026journal-article

Archives of Disease in Childhood

Medicines for children and young people who seek support around gender: a horizon scanning study of the emerging medicines pipeline

Gill Norman, Ross Fairbairn, Emma Dobson, Chizoba Oparah, Ayomikun Ogunyemi, Niina Kolehmainen

Objective To provide intelligence and foresight about persistent evidence gaps in medicines for children and young people experiencing gender incongruence or dysphoria. Design A horizon scan, with foresight analysis, of clinical trial registries. Setting Global. Patients Children and young people (aged 0–17 years) experiencing gender incongruence or dysphoria. Interventions Any medicine under evaluation in an ongoing study registered on a clinical trial registry. Main outcome measures Any. Results We identified 15 …