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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
25.08.2026journal-article

European Geriatric Medicine

Preoperative antithrombotic use is associated with delayed mobilization and plural blood transfusions following hip fracture surgery: a case–control study

Henrik Nupponen, Hanna Pajulammi, Anssi Korppi, Esa Jämsen

Abstract Purpose Early surgical treatment is important to allow a prompt start for rehabilitation after hip fracture. In patients using antithrombotic drugs, the surgery is often delayed, but it is unclear how this affects early post-operative recovery. Methods The course of treatment and early post-operative outcomes of hip fracture patients, aged ≥ 70 years, using either warfarin, direct oral anticoagulants (DOACs), or adenosine diphosphate. (ADP) inhibitors were compared to age- and sex-matched controls not usin …

25.08.2026journal-article

Geriatrics & Gerontology International

Weekend Warrior Physical Activity, Sedentary Behavior, and Incident Disability in Middle‐Aged and Older Adults: A UK Biobank Accelerometer Study

Xuan Zhu, Heyan Xia, Tao Sun, Xiaojun Wang

ABSTRACT Aim Regular moderate‐to‐vigorous physical activity (MVPA) is associated with lower risks of functional decline and disability. Whether concentrating MVPA into 1 or 2 days per week—the “weekend warrior” pattern—is associated with disability risk similarly to regularly distributed activity remains unclear, particularly among individuals with high sedentary behavior. Methods We analyzed wrist‐worn accelerometer data from 41 225 UK Biobank participants without identifiable baseline disability based on availabl …

25.08.2026journal-article

Journal of Racial and Ethnic Health Disparities

Changes in Racial Disparities in Viral Suppression Among People with HIV from 2013–2020: A Statewide Cohort Study

Cuihong Huang, Xueying Yang, Chen Zhang, Fanghui Shi, Jiajia Zhang, Bankole Olatosi, Sharon Weissman, Xiaoming Li

Abstract Objective Limited studies have sought to qualify the extent and trends of racial disparities in viral suppression (VS) among people with HIV(PWH) across the Southern US. This study aims to examine the spatiotemporal trend and structural social determinants of racial disparities of VS. Methods A population-based retrospective cohort study across all counties in South Carolina (SC) from 2013 to 2020. Linear trend test was employed to explore the temporal trend of the disparity indices (Black to White Ratio [ …

25.08.2026journal-article

Scientific Journal of Economics and Management Research

The Impact of Commercial Health Insurance on Household Consumption in the Context of Population Aging

Jinxia Liu, Shuang Zhu

Against the strategic backdrop of expanding domestic demand and addressing population aging, this study examines the impact of commercial health insurance on household consumption using provincial panel data from China for 2014–2024. The results show that commercial health insurance significantly promotes household consumption expenditure, crowds out basic consumption, and positively affects developmental and enjoyment-oriented consumption. This positive effect is persistent, with lagged health insurance developmen …

25.08.2026journal-article

Jurnal Biologi Tropis

HIV-Associated Dementia: Pathogenesis, Risk Factors, Diagnosis, and Management – A Literature Review

Baiq Tasyfa Hasya Auliya Tsaniya, Fidelya Fitria Hakim, I Wayan Putra Kesumantara, Sheilla Ninditya Putri, Herpan S. Harahap

HIV-associated dementia (HAD) is the most severe form of HIV-associated neurocognitive disorders (HAND), characterized by significant cognitive impairment and decline in daily functioning. Despite the widespread use of antiretroviral therapy (ART), neurocognitive impairment remains an important clinical challenge among people living with HIV. This review aimed to summarize current evidence regarding the pathogenesis, diagnosis, risk factors, and management of HIV-associated dementia. The study was conducted using a …

25.08.2026journal-article

Frontiers in Immunology

Mitochondrial homeostasis and aging: the mtDNA-cGAS-STING axis

Ling Wang, Zhengwei Zhang, Binbin Xia, Jun Li, Hongmei You

Aging and its associated diseases have become an increasingly severe global health challenge, not only significantly exacerbating the global disease burden but also posing a continuous threat to public health systems worldwide. During the aging process, the aberrant release of endogenous mitochondrial DNA (mtDNA) is a key trigger for the activation of the cGAS–STING innate immune pathway. Existing research has confirmed that the overactivation of the cGAS–STING pathway is the core molecular mechanism driving the se …

25.08.2026journal-article

Mindfulness

Efficacy of Mindfulness-Based Stress Reduction Versus Lifestyle Education for Fluid and Driving-Related Cognition in Older Adults: Results from the Healthy Agers Randomized Controlled Trial

Madhura Phansikar, Megan E. Fisher, Elizabeth Jean Duraney, Anita Shankar, Nathan McPherson, Rosie Canter, Stephanie Aghamoosa, Rebecca Andridge, Ruchika S. Prakash

Abstract Objectives The current study examined the efficacy of mindfulness-based stress reduction (MBSR), compared with an active control lifestyle education program (LifeEd), in improving fluid and driving-related cognition in older adults. Dose–response associations between mindfulness practice and treatment gains were also examined. Method One hundred fifty participants were randomized to one of two groups. Outcomes were assessed at pre-intervention, post-intervention, and 6- and 12-month follow-ups. Results The …

25.08.2026journal-article

World Journal of Surgery

High Undertriage in Geriatric Trauma in a Developing Trauma System: Implications for Trauma Team Activation Criteria

Muhamad Izwan Ismail, Japsimranjit Kaur, Rizasohaini Baseri, Norfarizan Azmi

ABSTRACT Introduction Older adults are at increased risk of adverse outcomes after trauma but are frequently undertriaged because age‐related physiological changes may mask injury severity. We evaluated the performance of our institutional trauma team activation (TTA) criteria in patients aged ≥ 65 years within a developing trauma system. Methods We conducted a retrospective observational study using a trauma registry at a tertiary referral hospital in Malaysia between July 2024 and December 2025. Consecutive traum …

25.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

PHYSICAL EXERCISE AND COGNITIVE HEALTH IN AGING: AN INTEGRATIVE LITERATURE REVIEW

Gabriel Vinícius Reis de Queiroz, Ricardo Sérgio Chucre Rocha Junior, Soly Guedes Barbosa, Pedro Henrique Avelino Oliveira, Jânio de Jesus Gonçalves Júnior, Felipe Farias Campos, Jefferson Luiz de Souza e Silva, Lisandro Contente Gomes, Marcos José Castro dos Santos, Tatiane Bahia do Vale Silva

Objective: To analyze the available scientific evidence on the effects of physical exercise on cognitive health in older adults. Methods: An integrative literature review was conducted in MEDLINE/PubMed, LILACS/BVS, SciELO, Scopus, Web of Science, and Embase, covering publications from 2020 to 2026. Original studies involving individuals aged 60 years or older, or samples with a mean age of 60 years or older, that investigated the relationship between physical exercise and cognitive outcomes were included. The sele …

25.08.2026journal-article

Frontiers in Nutrition

Effects of resistance training combined with creatine supplementation on muscle strength, physical function, and muscle mass in older adults: a systematic review and three-level meta-analysis

Lingzi Yao, Doudou Yang, Jiajia Gao

Objective To systematically evaluate the additional effects of creatine supplementation combined with resistance training, compared with resistance training alone, on muscle strength, muscle mass and physical function in older adults. Methods PubMed, Embase, the Cochrane Library and Web of Science were searched from inception to 20 May 2026. Randomized controlled trials enrolling older adults aged 60 years and older and comparing creatine supplementation plus resistance training with resistance training alone or pl …

25.08.2026journal-article

BMC Geriatrics

Multidisciplinary prognostic accuracy in severe frailty: assessing short-term survival predictions in hospitalized older adults

Elena Pinardi, Simona Umidi, Beatrice Tonus, Jacopo Usai, Alice Margherita Ornago, Maria Cristina Ferrara, Alberto Finazzi, Chukwuma Okoye, Paolo Mazzola, Gianlorenzo Scaccabarozzi, Giuseppe Bellelli

Abstract Background The increasing number of hospitalized older adults with severe frailty and limited life expectancy highlights the need for accurate short-term prognosis to inform care planning, effective communication, and resource allocation. However, survival prediction in this population is underexplored. This study aimed to assess (i) agreement among healthcare professionals on short-term prognosis, (ii) predictive accuracy of multiprofessional survival estimates, and (iii) factors affecting prognostic accu …

25.08.2026journal-article

Frontiers in Medicine

Older adult patients with out-of-hospital pressure injuries: a single-center retrospective study in a tertiary hospital in China

Hongling Sun, Caiyun Xu, Yan Sun, Hui Wang, Shuyan Li, Jinping Xia

Background To investigate the prevalence and clinical characteristics of pressure injuries (PIs) present at hospital admission among older adult patients, and to identify factors influencing healing outcomes through a single-center retrospective analysis. The goal is to inform nursing strategies for PI management in older adults. Methods Data were retrieved from a self-developed pressure injury prevention and management platform at a tertiary hospital in Zhejiang Province. Patients aged ≥60 years admitted between J …

25.08.2026journal-article

Geriatrics

Novel Hypothesis on Phase Angle as a Candidate Marker Associated with Physiological Reserve in Geriatric Patients in Long-Term Care

Alejandro Padilla Isassi, Rosalba Maya Hernández, María Elisa Otero Cerdeira, Ingrid Alejandra Abarca Salinas

Background: Physiological reserve reflects the capacity of the organism to maintain homeostasis under biological stress. We suggest the hypothesis that phase angle derived from bioelectrical impedance analysis could be a potential objective marker of Physiological reserve. Methods: An analytical cross-sectional study was conducted in 45 older adults residing in long-term care units at Hospital Español de México (2025). Frailty was assessed with the FRAIL index, sarcopenia using EWGSOP2 criteria, functionality with …

25.08.2026journal-article

JURNAL ILMIAH LIVING LAW

Assessing Local Elections in Indonesia by Regional Representative Councils and Local Elections by the People

Hanif Hardianto, Nina Farliana

This article examines the dynamics of the legal–political framework governing local elections in Indonesia by situating the debate between direct elections by the people and indirect elections through Regional People’s Representative Councils (DPRD) within the perspective of constitutional democracy. This study employs a qualitative juridical-normative research method with a descriptive-analytical approach, relying on the analysis of statutory regulations, Constitutional Court decisions, and relevant legal and poli …

25.08.2026journal-article

Advanced Science

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang

ABSTRACT Repairing peripheral nerve injury remains a clinical challenge due to its limited regenerative capacity and the situation is further compounded with age. In this study, we identified the dysregulated repair program of Schwann cells (SCs) as a key feature of the aging‐dependent impairment of nerve regeneration, mediated by dual influence of ferroptosis. The ferroptosis‐stressor‐rich microenvironment inhibits SC function in regenerating nerves. Moreover, the persistent intracellular ferroptosis stressor accu …

25.08.2026journal-article

Dementia

Studying What Matters: South Texas Community-Driven Dementia Research Priorities

Sara S. Masoud, Juana Escareño, Belinda Flores, Byeong Yeob Choi, Karla Daniela Lopez Lorenzo, Shanae L. Rhodes, Quetzaly Zenil, Carole L. White

South Texas has among the highest dementia prevalence rates in the United States, yet communities in the region remain consistently underrepresented in dementia research. Aligning research studies with what matters to communities most impacted by dementia is critical in addressing the crisis of research exclusion. This participatory study sought to identify community-driven dementia research priorities grounded in the experiences and needs of South Texas residents impacted by dementia. A two-year community-engaged …

25.08.2026journal-article

ACS Applied Energy Materials

H2O/CO2-Induced Surface Aging of Lithium Borate-Modified Li6.6La3Zr1.6Ta0.4O12 Garnet Electrolytes and Its Impact on Lithium-Metal Interfacial Stability

Xinhao Yang, Nataly Carolina Rosero-Navarro

Abstract Lithium borate glass is an effective sintering additive for reducing the processing temperature of garnet-type Li6.6La3Zr1.6Ta0.4O12 (LLZTO) solid electrolytes owing to its ability to promote densification and improve ionic conductivity; however, its influence on environmental surface stability remains insufficiently clarified. Here, lithium-borate-modified LLZTO ceramics were investigated with emphasis on H2O/CO2-induced surface aging and the resulting impact on Li-metal interfacial stability. The LBO-mod …

25.08.2026journal-article

Frontiers in Medicine

Comparative effectiveness and dose–response relationship of exercise-based interventions for muscle mass in older women with sarcopenia: a systematic review and network meta-analysis

Xinyi Gou, Junhui Zhu, Xinmiao Feng, Dongze Li, Qi Gao, Bin Ruan

Background Exercise and nutrition are the principal non-pharmacological strategies for sarcopenia, but the relative effects of different exercise combinations and the dose required to improve muscle mass in older women remain uncertain. This study compared exercise-based interventions and examined the dose-response relationship. Methods PubMed, Web of Science, Embase, the Cochrane Library, and EBSCO were searched from inception to 1 July 2026. Eligible trials enrolled women aged ≥ 60 years female with sarcopenia. R …

25.08.2026journal-article

Journal of Social Science and Humanities

Uncertainty Regarding Access to Justice for Rural People: The Perspective of Salish and Village Courts

Sanjida Mostafiz

Rural people in Bangladesh face various obstacles in the justice system, from the primary justice system to the formal level, such as arbitration. Although the establishment of the rule of law is an expected aspect of a modern state system, the suffering of ordinary people at various stages of the legal process is endless. And the level of suffering is even greater among rural people. Ordinary people in villages are accustomed to the informal justice system in this country. The article highlights why people resort …

25.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

INTERFAITH COLLABORATION AND HUMAN RIGHTS IN WELCOMING VULNERABLE PEOPLE: FOUNDATIONS AND PERSPECTIVES OF THE TOCA PROJECT

Elizandro Poletto, Elson Santos Silva

This study analyzes interreligious cooperation as a strategy for welcoming, protecting, and promoting the human rights of people experiencing social vulnerability. It assumes that religious organizations and faith-based initiatives play an important role in building solidarity networks, particularly in contexts marked by poverty, exclusion, migration, lack of protection, and weakened social ties. The study discusses the legal and social foundations of such action, considering human dignity, equality, religious free …

25.08.2026journal-article

Indoor and Built Environment

The impact of the community life circle on the quality of life of older adults based on a structural equation model

Jingyu Yu, Nianzhang Mao, Guixia Ma, Mei-yung Leung

With the intensification of population aging in China, the community life circle (CLC), as an important planning model for enhancing the quality of life (QoL) of older adults, has garnered increasing attention. This study thus aims to investigate the complex impact of various CLC components on the QoL of older adults through a large-scale questionnaire survey. This study designed a structured questionnaire to investigate the complex relationships between CLC components and QoL domains from the perspective of older …

25.08.2026journal-article

Brain Sciences

Online Comprehensive Care Therapy Complementary Program Improves Quality of Life in People with Parkinson’s Disease

Diego Santos García, Pablo Campo Prieto, Carmen M. Breijo García, Lucía Dafonte Gil, Juan Pereiro Nogueira, Jessica Blanco López, Francisco Doblas

Objectives: Non-pharmacological therapies are a cornerstone of Parkinson’s disease (PD) treatment, but there is not enough evidence of their benefit when delivered altogether online. Our objective was to analyze the efficacy and safety of an online comprehensive care therapy program (OL-CCTP) in people with PD (PwP). Material and methods: This was a proof-of-concept experimental, prospective, 6-month interventional study comparing a PD treatment group (PwP-T) with a control group (PwP-C). The OL-CCTP included group …

25.08.2026journal-article

Alzheimer Disease & Associated Disorders

Discordance Between Cognitive Impairment Status and Claims-Based ADRD Diagnosis

Min Hee Kim, Lisandro D. Colantonio, M. Maria Glymour, Rita Hamad, Julia Adler-Milstein, Kiarri N. Kershaw, John Boscardin, Zhixin Wang, Ayse Sert Oti, Virginia J. Howard

Introduction: Understanding the concordance between incident cognitive impairment status and the diagnosis of Alzheimer disease and related dementias (ADRD) is clinically important, as a diagnosis serves as the gateway for treatment, care planning, and supportive services. Methods: Using the REGARDS cohort (2006 to 2021) linked to Medicare claims, we examined the discordance between incident cognitive impairment and claims-based ADRD diagnoses. Directly standardized diagnosis rates were estimated by year, overall, …