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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Medicine

Intravitreal exposure to the SARS-CoV-2 spike protein is associated with aggravated retinal lesions in a murine model of central retinal vein occlusion

Siyi Liu, Zhihui Zhang, Yumin Zhang, Xinglong Wang, Yibin Yu, Yunshan Cao, Yan Zhang

Purpose To explore effects of SARS-CoV-2 ocular infection on severity of central retinal vein occlusion (CRVO) and the associated cellular and molecular clues. Methods The spike protein (SP) was intravitreally administered to mimic the pathological process of SARS-CoV-2 ocular infection. Eight-week-old C57BL/6 male mice were randomly divided into 5 groups: normal control (NOR), CRVO, 0.2 SP + CRVO, 0.4 SP + CRVO, and 0.8 SP + CRVO groups. The CRVO group was intravitreally injected with phosphate-buffered saline, an …

03.09.2026journal-article

Frontiers in Surgery

Adult Wilms tumor revealed after radical nephrectomy for a renal mass initially suspected to be clear-cell renal cell carcinoma: a case report

Kunxiang Wang, Jin Long, Cheng Pan, Yaowen Zhang, Peng Ren, Xiaojun Wan

Introduction Nephroblastoma is the most common malignant renal neoplasm in children but remains exceptionally rare in adults. Compared with pediatric cases, adult Wilms tumor (AWT) often presents greater diagnostic challenges and is associated with larger tumor volumes and more advanced disease at diagnosis, contributing to poorer prognoses. Consequently, adults with Wilms tumor have significantly worse outcomes than pediatric patients. Because of the limited number of reported cases, no standardized management alg …

03.09.2026journal-article

Frontiers in Psychiatry

Case Report: Unmasking catatonia in adolescents: a potential triggering role of corticosteroids in two clinical cases

Margherita De Biase, Roberto Averna, Gianluca Sesso, Milena Labonia, Stefano Vicari

Background Catatonia is a transdiagnostic syndrome marked by motor, behavioral, and autonomic disturbances. Corticosteroids, commonly used to treat suspected neuroinflammatory conditions, may rarely precipitate or exacerbate psychiatric symptoms, including catatonia, in children and adolescents. Methods We describe two adolescent girls who developed catatonia following corticosteroid therapy for suspected encephalitis, despite negative cerebrospinal fluid and blood markers. Clinical courses, diagnostic workups, and …

03.09.2026journal-article

Indian Journal of Nuclear Medicine

Context-Grounded PET-CT Report Generation Using LoRA-Fine-Tuned BioMedLM with Physician Validation and Safety Evaluation

Dibya Prakash, Pramukh Kulkarni, Venkatesh Rangarajan, Manoj Kumar

Objectives: Positron emission tomography-computed tomography (PET-CT) reporting is cognitively demanding, requiring integration of quantitative metabolic data and anatomical findings across multiple body regions. Existing segmentation and analysis models provide anatomical and physiological parameters, but not cohesive physician-style reports; however, they can supply a structured clinical context for a dedicated PET-CT language model. Existing large language model (LLM) approaches for radiology report generation p …

03.09.2026journal-article

Military Medicine

Past-Year Co-Use of Alcohol and Opioid and Suicidal Behaviors in U.S. Adults with Prior Military Service

Ava C Santiago, Anwar E Ahmed, Jangho Yoon, Karl C Alcover

Abstract Introduction Alcohol use and opioid use independently increase the risk of suicidal behaviors. These substances are also frequently used concurrently, yet the extent to which their co-use contributes to suicidal behaviors at the population level remains insufficiently understood. This gap is particularly relevant among adults with prior military service, who experience elevated burdens of chronic pain, opioid exposure, and mental health comorbidities. We therefore examined whether past-year alcohol–opioid …

03.09.2026journal-article

Acta Neurochirurgica

Risk stratification and treatment outcomes after surgical treatment of 0unruptured intracranial aneurysms: a single-center retrospective review

Jessica Y Jung, Alex Kostynskyy, Ronit Agid, Pascal Mosimann, Timo Krings, Hugo Andrade Barazarte, Michael Tymianski, Ivan Radovanovic

Abstract Purpose Management of unruptured intracranial aneurysms (UIAs) requires weighing rupture risk against treatment risk. As endovascular techniques have evolved, microsurgical intervention has become increasingly concentrated at high-volume centers and reserved for complex cases, potentially representing a higher-risk endeavor than reflected in earlier series. A contemporary evaluation of patient and aneurysm-related features associated with surgical risk and postoperative outcomes is needed. Methods We condu …

03.09.2026journal-article

Ultrasound

Investigation of S-Detect AI (a computer-aided diagnosis tool) versus ultrasound operators for thyroid nodule classification using British Thyroid Association guidelines: A pilot diagnostic accuracy study

Kieran Walker, James Michael, Mark Ballard, Geoffrey Chilvers, Steve Colley, Khalid Hussain, Lloyd Rickard

Introduction: Thyroid nodules affect more than 60% of the population, approximately 5% being malignant. The British Thyroid Association U-classification guides ultrasound risk stratification across the United Kingdom but is subject to inter-observer variability. Artificial intelligence decision support tools may offer more standardised assessment, yet no peer-reviewed study has validated S-Detect, a computer-aided diagnosis tool integrated into Samsung ultrasound systems, against the British Thyroid Association fra …

03.09.2026journal-article

Journal of Public Health and Preventive Medicine

Research Progress on Intervention Measures for Fall Prevention among the Elderly

Sharon R Lewis, Lisa McGarrigle, Ewa Klimek Piskorz

Falls represent one of the most significant public health challenges facing the aging global population, contributing substantially to morbidity, mortality, and healthcare costs. This review synthesizes recent research progress on intervention measures for fall prevention among older adults, encompassing exercise-based interventions, multifactorial approaches, medication management and deprescribing, digital health technologies, nutritional supplementation, cognitive-behavioral strategies, and environmental modific …

03.09.2026journal-article

Langenbeck's Archives of Surgery

Seeing beyond Calot’s triangle: routine indocyanine green fluorescence cholangiography during laparoscopic cholecystectomy - a prospective consecutive single-surgeon study of visualization performance and limitations

Palanivelraju Gopalakrishnan, B. R. Gopinath, Yirupaiahgari K. S. Viswanath, Vikramjit Mitra, Abdalla Hassan

Abstract Purpose To characterise the visualisation performance, limitations, anatomical findings and safety of routine indocyanine green (ICG) fluorescence cholangiography workflow in a consecutive elective and emergency laparoscopic cholecystectomy cohort. This descriptive study was not designed to establish superiority over white-light surgery or intraoperative cholangiography (IOC). Methods Prospectively collected data were analyzed for consecutive adults undergoing elective or emergency laparoscopic cholecystec …

03.09.2026journal-article

Cancers

Clinical Applicability of the WHO Reporting System for Axillary Lymph Node Fine-Needle Aspiration in Invasive Breast Carcinoma

Mariana Canepa, Allison Chang, Stephanie L. Graff, Yihong Wang

Background: Axillary lymph node (ALN) fine-needle aspirations (FNAs) can guide the next steps in the management of patients with invasive breast carcinoma (BC). The objective is to evaluate the diagnostic performance of ALN FNA in the detection of metastatic breast carcinoma. Methods: We evaluated ALN FNAs from 2020 to 2024 to determine the risk of malignancy (ROM) of different cytologic diagnostic categories using a general WHO cytology reporting system framework (insufficient, benign, atypical, suspicious, and ma …

03.09.2026journal-article

Physics in Medicine & Biology

A physics-informed decomposition network for carbon ion radiotherapy dose monitoring: a proof-of-concept study

Xin-Yu Hu, Yan Li, Wei-Guang Li, Yu-Ying Yin, Chao Yang, Cheng Chang, Ming-Qing Wang, Kai-Wen Li, Xueying Yang, Li-Sheng Geng

Abstract Objective. In-beam positron emission tomography (PET) provides a promising strategy for dose monitoring in carbon ion radiotherapy (CIRT), but accurate dose prediction remains difficult due to the complex, nonlinear relationship between positron-emitter activity and physical dose deposition. This proof-of-concept study aimed to improve activity-to-dose mapping by developing decomposition-based deep learning frameworks with auxiliary physical supervision. Approach. Idealized Monte Carlo (MC) simulations wer …

03.09.2026journal-article

Journal of Addiction Medicine

Impact of Addiction Consult Service on Alcohol Use Disorder Medications and Postdischarge Outcomes

Thomas J. Reese, Kristopher A. Kast, David Marcovitz, Clayton Korson, Hilary A. Tindle, Sahit N. Menon, Ashley A. Leech, Lisa Stewart-Kast, Adam Wright, Mauli V. Shah, Amanda von Horn

Objectives: This study aims to evaluate the association between Addiction Consult Service (ACS) involvement and initiation of medication for alcohol use disorder (MAUD), as well as postdischarge outcomes through 90 days, among adults hospitalized with alcohol-related conditions.​ Methods: We conducted a retrospective cohort study at a large academic medical center from 2018 to 2025. The exposure of interest was receipt of an ACS consultation during hospitalization. Primary outcomes were inpatient MAUD initiation, M …

03.09.2026journal-article

HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery

Nutritional Strategies for Recovery in Overhead Athletes: A Review

Hillary Ake

This review article discusses the critical role of nutrition in optimizing recovery for overhead athletes following intense or damaging exercise that induces oxidative stress. The components of recovery nutrition include replenishing glycogen stores, repairing muscle tissue, and rehydrating, while also addressing inflammation, promoting sleep, and matching workload to level of recovery. Detailed information is provided on subjects such as postactivity carbohydrate and fluid requirements, protein synthesis, nutritio …

03.09.2026journal-article

International Journal of Pharmacy Practice

A survey of service provision and use of consultation rooms and clinical records in community pharmacies

Natalie Gauld, Frances Redmond, Arier Lee, Trudi Aspden

Abstract Objectives To examine consultation room use, services delivered, and use of clinical records in New Zealand (NZ) community pharmacies. Methods Community pharmacies were surveyed. Analysis included descriptive statistics, Fisher exact tests, t-tests, and ANOVA. Key findings Of 104 responses (42% response rate), 92.2% had consultation room/s, used on average eight times per day. Most respondents wanted to improve their consultation room. Micro-credentialled services usually used consultation rooms, but some …

03.09.2026journal-article

Medical Care

Patient Outcomes and Nurse Understaffing in For-Profit Hospitals

Matthew D. McHugh, Karen B. Lasater, K. Jane Muir, Angelo Petto, Trissa Lyman, Linda H. Aiken

Background: For-profit hospital ownership has been associated with worse patient outcomes, but the mechanisms remain unclear. Underinvestment in nurse staffing is a plausible pathway linking for-profit ownership to performance. Objectives: To examine whether differences in nurse staffing mediate associations between for-profit hospital ownership and patient, nurse, and hospital outcomes. Design: Cross-sectional study using 2024 data on hospital ownership, registered nurse survey responses, Medicare claims, and Hosp …

03.09.2026journal-article

Journal of Cardiovascular Development and Disease

Sports Cardiology: From Diagnosis to Clinical Management—Towards Individualized Cardiovascular Care Through Exercise

Christos Kourek, Eleftherios Karatzanos, Stavros Dimopoulos

This Special Issue, “Sports Cardiology: From Diagnosis to Clinical Management”, was developed to reflect the expanding scope of sports cardiology, a field that now extends well beyond the assessment of competitive athletes alone [...]

03.09.2026journal-article

Acta Neurochirurgica

Clinical course of traumatic cerebral venous sinus thrombosis: Insights from a UK major trauma centre

Sheikh Muktadir Bin Momin, Faheem Anwar, Georgina Shallard, Azam Ali Baig, Yousra Rasool, Anam Fatima, Andrew R. Stevens, Philip Ho, Anne Preece, David James Davies, Antonio Belli, Ramesh Chelvarajah, Philip J. O’Halloran

Abstract Background Traumatic venous sinus thrombosis (tCVST) is a recognised complication of traumatic brain injury (TBI), usually secondary to adjacent skull fractures or intracranial haemorrhage. The optimal timing of diagnostic CT venography (CTV) and anticoagulation initiation remains uncertain. Methods A retrospective cohort study was performed at Queen Elizabeth Hospital Birmingham, a UK Major Trauma Centre, including patients aged > 16 years with radiologically-confirmed tCVST between January 2020-December …

03.09.2026journal-article

Journal of Robotic Surgery

Failure modes of robotic-assisted arthroplasty platforms in Australia: a descriptive analysis of TGA adverse event reports

Dylan Rowe, Mariam Rowe

Abstract Robotic-assisted arthroplasty is increasingly performed using technically distinct platforms. The types of device problems reported for different robotic arthroplasty platforms have not been characterised using Australian national surveillance data. The TGA Database of Adverse Event Notifications (DAEN) was searched for robotic arthroplasty adverse events reported between July 2012 and December 2025. Failure modes were extracted from the DAEN classification, and qualitative review of event narratives was p …

03.09.2026journal-article

Journal of Imaging Informatics in Medicine

Multi-centre Validation of Automated Outer-to-Outer Wall Segmentation of Infrarenal Abdominal Aortic Aneurysms Using a nnU-Net Based Model

Cas H. F. Hendricks, Willemina A. van Veldhuizen, Amin Ranem, Bram Fioole, Rogier H. J. Kropman, Jelmer M. Wolterink, Jean-Paul P. M. de Vries

Abstract Accurate outer-to-outer wall aortic segmentation is essential for abdominal aortic aneurysm (AAA) assessment and endovascular aneurysm repair (EVAR) planning, yet manual segmentation is time-consuming and impractical for routine use. This study aimed to validate a pre-trained open-source nnU-Net–based model for fully automated outer-to-outer wall segmentation of the abdominal aorta in AAA patients. In this retrospective multicentre observational validation study, 75 consecutive AAA patients (25 per centre) …

03.09.2026journal-article

Journal of Clinical Medicine

Updating the Prevalence of H. pylori and Extensive Precancerous Lesions in the Stomach: Results of a Multicenter, Endoscopic Study

Angelo Zullo, Giulio Cozza, Guido Manfredi, Saverio Alicante, Andrea Mega, Eugenio Marconato, Salvatore Russo, Benedetta Toro, Luca De Luca, Marco Magistroni, Bastianello Germanà, Nunzia Russo, Elisabetta Martinelli, Alessandra Loiodice, Dino Vaira, Giulia Fiorini, Giuseppe Scaccianoce, Berardino D’Ascoli, Roberto Vassallo, Vincenzo De Francesco, Gianluca Esposito, Irene Ligato, Marcello Maida, Federico Bonomo, Giovanna Ruggiero, Andrea Boccuto, Francesca Galeazzi, Anna Ros, Angelo Milano, Rachele Ciccocioppo, Fabio Monica, Marco Sartori, Giulia Leonardi, Raffaele Manta

Background/Objectives: H. pylori is the main preventable risk factor for gastric cancer through the development of extensive precancerous lesions, namely mucosal atrophy and intestinal metaplasia. Methods: This multicenter, nationwide study enrolled consecutive patients who underwent their first upper gastrointestinal endoscopy with standard biopsies. Clinical, endoscopic and histological data were gathered for statistical analysis using both univariate and multivariate analyses. Results: Data from 775 patients wer …

03.09.2026journal-article

Veterinary Sciences

Human Allergy to Cats and Dogs: Molecular and Environmental Determinants, Diagnosis, and Precision Management

Jungwhan Chon, Kun-Ho Seo, Yeonghun Jee, Kihoon Kim, Kwang-Young Song

Cat- and dog-derived allergenic proteins are important indoor exposure sources, but allergen exposure, IgE sensitization, and clinically manifest allergy are distinct biological and clinical states. Major molecules include the cat secretoglobin Fel d 1 and several dog lipocalins, including Can f 1, together with serum albumins, kallikreins, and other components that can contribute to species-specific sensitization or cross-reactivity. These proteins are transported in the environment on heterogeneous carriers such …

03.09.2026journal-article

European Journal of Dental Education

Knowledge, Attitude and Perception of Dental Professionals and Students Toward Traditional and Complementary Medicine: A Cross‐Sectional Study

Ayse Tas, Nelli Agbulut

ABSTRACT Purpose/Objectives Traditional and Complementary Medicine (TCM) has gained global recognition, and Turkey officially regulates 15 TCM practices within its healthcare system. Despite increasing interest, the knowledge and attitudes of dental professionals and students remain underexplored; this study aims to evaluate knowledge, attitudes, and perceptions toward TCM among dental students, general practitioner dentists (GPDs), and dental specialists in Turkey. Methods A cross‐sectional questionnaire was condu …

03.09.2026journal-article

JAMA Network Open

Large Language Models and Adverse Event Detection Within Immunotherapy Clinical Trials

Marianna V. Elia, Isabel D. Friesner, Daniel Kwon, Lisa Ni, Sumi Sinha, Yuta Ishiyama, Travis Zack, Mark Bridge, Lawrence Fong, Julian C. Hong

This comparative effectiveness study examines the ability of a large language model vs human reviewer consensus to identify adverse events from encounter notes from 4 randomized clinical trials.