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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

BMC Psychiatry

A holistic approach to support people with mental illness and mental ill-health: a mixed-methods study of clubhouse participation and its perceived impact

Hanna Isabel Løyland, Ingrid Engebretsen, Marianne Lefsaker Johansson, Anne Hellum, Erik Magnus Sæther, June Ullevoldsæter Lystad, Kine Pedersen

Abstract Background Mental illness poses health and societal challenges. The Clubhouse model offers a community-based approach aimed at promoting social inclusion and enhancing quality of life for individuals experiencing mental illness. We aimed to identify the characteristics of individuals engaging with Clubhouses in Norway (referred to as members), examine their patterns of attendance and engagement, and evaluate their experiences with participation in Clubhouse activities. Methods We employed a mixed-methods d …

26.08.2026journal-article

Research on Aging

Connected and Eager to Learn: Digital Skills, Challenges, and Unmet Needs of Older Adults in Long-Term Care Facilities

Annalise Baines, Eszter Hargittai, Gerta Lokaj

This study explores the digital skills and challenges of older adults living in long-term care settings. We conducted 14 focus group interviews with 59 residents in Switzerland, with an average age of 80, to identify the competencies they possess and the skills they lack. Participants described using digital tools to stay connected and maintain autonomy. However, they also reported barriers such as cognitive limitations, rapid technological changes, and difficulty managing digital information. Despite these challen …

26.08.2026journal-article

Comunicación y Sociedad

Jóvenes y desafección política en contextos de polarización. El caso de la juventud universitaria en el proceso electoral de 2024 en México

Maricela Portillo Sánchez

El objetivo de este artículo es analizar la desafección política de jóvenes universitarios en el contexto electoral de 2024 en México, comparando los datos con Kriger y Toribio (2023). Los resultados apuntan a una confianza relativa sobre el voto y la política, así como a la centralidad de la información que consumen a través de las redes sociales y los medios de comunicación. Las conclusiones indican que desafección no implica desinterés por parte de la juventud, sino hartazgo de una forma de ejercer la política p …

26.08.2026journal-article

AIDS

The additive value of coronary calcium in identifying cardiovascular risk in ageing people with HIV

Maithili Varadarajan, Ruth Byrne, Abethale Al-Hussaini, Brian Halliday, Edward Nicol, Mark Nelson, Alan Winston, Marta Boffito

In people without HIV, raised coronary artery calcium scores (CACS) are linked to increased cardiovascular risk. HIV is associated with elevated CACS, but risk factors beyond smoking and diabetes are not well established. Data on 779 individuals with HIV who underwent a CACS scans (median age 55) were collected. CACS better predicted adverse outcomes (e.g. major adverse cardiovascular events (MACE), death, heart failure) than Q-risk scores. Advanced imaging research may improve major cardiovascular risk prediction …

26.08.2026journal-article

Pakistan Journal of Gastroenterology

Urine Like Diarrhea in Older Children: Two Case Reports

Md Benzamin, ASM Bazlul karim

Background: Urine like diarrhea’ is seen in Congenital Chloride Losing Diarrhea (CCLD), which usually starts during neonatal period. But without prior history of CCLD, it is rare in older children, and no reported case till now. Case presentation: Two Bangladeshi children, presented with ‘urine-like diarrhea’ for more than 14 days, without any previous history or suggestive findings. All investigations were negative for any etiology except fecal impaction seen on x-ray abdomen. After disimpaction, both child were d …

26.08.2026journal-article

Frontiers in Endocrinology

Atherogenic index of plasma as a simple marker for NAFLD risk stratification in community-dwelling older adults: a cross-sectional study with incremental predictive value assessment

Mengyuan Xiao, Chengwen Xiao, Jiayu Zhang, Yuchen Ji, Jiayan Zhuang, Yingqi Chen, Zhihong Yuan, Siying Chen

The atherogenic index of plasma (AIP), calculated as log 10 (triglycerides/HDL-C), reflects atherogenic dyslipidemia and is associated with insulin resistance. Its continuous dose-response relationship and incremental predictive value for non-alcoholic fatty liver disease (NAFLD) beyond traditional risk factors remain undefined in community-dwelling older adults—a population with a high metabolic comorbidity burden where low-cost, integrated risk markers are urgently needed. Methods From 5,783 residents aged ≥65 ye …

26.08.2026journal-article

Diseases

Oral Structural and Functional Impairment in Relation to Depressive Outcomes in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies

Lavinia-Alexandra Moroianu, Laurentiu Dragus, Stefan Rosca, Magdalena Rusu Negraia, Valeriu Ardeleanu, Rares Nicolae Vadana, Ionelia State, Georgel Mihu, Madalina Nicoleta Matei, Simona Dana Mitincu Caramfil

Background/Objectives: Oral structural and functional impairment and depressive outcomes frequently coexist in older adults, but the strength and interpretation of their association remain uncertain. This systematic review and meta-analysis evaluated whether poorer oral status or function is associated with depressive outcomes in older populations. Methods: Six databases were searched for observational studies published from 1 January 2016 to 5 January 2026, with an update on 19 April 2026. Eligible studies examine …

26.08.2026journal-article

Aging Cell

Associations Between Accelerometer‐Assessed Sleep Patterns, Proteomic Signatures, and Hallmarks of Aging in Adulthood

Ruiyi Liu, Jingsong Luo, Yangchang Zhang, Furong Wang, Jing Xu, Wangnan Cao, Shengzhi Sun

ABSTRACT The associations between objectively measured sleep patterns, the hallmarks of aging, and their shared proteomic signatures remain poorly understood. In this study, we utilized wrist‐worn accelerometer data, plasma proteomic profiles, and health records from the UK Biobank to examine the associations between six defined sleep patterns and nine established hallmarks of aging. We further identified proteins jointly associated with both sleep patterns and aging hallmarks. Longer total sleep duration, greater …

26.08.2026journal-article

Frontiers in Sports and Active Living

Can aerobic exercise really improve factors related to decision-making capacity in aging? What has been measured, what has been assumed, and what needs to change

Jonathan A. Cortés Silva, Christina A. Davis, Diego Lievano Parra, Valeria V. González

As populations age globally, cognitive decline has become one of the most pressing health challenges of our century. Early cognitive decline usually manifests as problems related to decision-making processes. In this context, aerobic exercise has emerged as a promising strategy for preserving and improving brain health. However, a critical question remains underexplored: whether improvements in executive function (EF) tasks truly reflect enhanced decision-making capacity, or whether they index more circumscribed ch …

26.08.2026journal-article

Psikoloji Çalışmaları / Studies in Psychology

Psychological Symptoms in Caregivers of Individuals Diagnosed with Dementia in Turkey: A Conservation of Resources Perspective

Elçin Yorulmaz, Gülay Dirik, Simge Balaban

Dementia is a disorder that is expected to increase in prevalence over the years and affects the daily lives of individuals. Because of its cognitive, emotional, and behavioral effects, dementia can impact a person's daily life and create a need for care. Since providing care involves many struggles, caregivers may experience numerous psychological symptoms. The purpose of the current study was to investigate the factors correlated with psychological symptoms experienced by caregivers of individuals diagnosed with …

26.08.2026journal-article

Frontiers in Immunology

Effect of blueberry consumption on regulatory lymphocyte phenotypes and NK cell functional activity in middle-aged and older adults with overweight or obesity: a randomized controlled trial

Abril I. Sánchez-Rosales, Sujatha Rajaram, Nadia Nemeh-Saad, Rawiwan Sirirat, Jacqueline Coats, Alan Cupino, Juli J. Unternaehrer, Joan Sabaté

Background Age-related changes in immune regulation and innate immune responses may be influenced by chronic low-grade inflammation associated with adiposity. Blueberries, rich in anthocyanins, may modulate inflammatory responses through effects on oxidative stress and phenolic metabolites; however, evidence from randomized controlled trials (RCTs) remains limited. We evaluated whether daily blueberry consumption modifies select cellular immune markers and inflammatory biomarkers in adults with overweight or obesit …

26.08.2026journal-article

Frontiers in Aging Neuroscience

Modulation of fronto-parietal and autonomic activity underpins preserved working memory in middle-aged adults

Myriam Cayre, Laure Spieser, Anaïs Guille, Nathalie Baril, Arnaud Weill, Caroline Chambon

Background Cognitive aging is a heterogeneous process, often diverging from chronological age. However, it remains unclear when early signs of cognitive decline emerge and which neurophysiological markers distinguish age-related cognitive alteration from preserved performances. This study aimed to identify early indicators of cognitive versus chronological aging. Methods In a group of middle-aged adults (MA, n = 60), we distinguished high performers (MA_HP; n = 24; mean age ± SEM 54.2 ± 0.6-year-old) from low perfo …

26.08.2026journal-article

Journal of Medical Internet Research

Naturalistic Online Language as a Marker of Depression in Midlife and Older Adults: Computational Text Analysis of Bluesky and Reddit Posts

Lauren Rutter, Andy Edinger, Marijn ten Thij, Lorenzo Lorenzo-Luaces, Danny Valdez, Johan Bollen

Abstract Background Social media use among older adults continues to grow. Many people use social media to establish meaningful social ties and discuss their mental health. Depression in midlife and older adults is a critical public health concern, yet scalable, sensitive methods for early detection remain limited. Natural language processing offers new opportunities to examine sentiment and mental health through online language in typically understudied populations. Objective This study examined whether sentiment …

26.08.2026journal-article

Revista da Associação Brasileira de Pesquisadores/as Negros/as (ABPN)

RACISMO, ESTEREÓTIPOS RACIAIS E IMPLICAÇÕES NAS TRAJETÓRIAS PROFISSIONAIS DE PESSOAS NEGRAS

Sabrina Prado Anjos, Quézia Costa Dias, Emerson Douglas Dos Santos Martins

Este artigo mapeia e sistematiza produções científicas sobre os efeitos do racismo e dos estereótipos raciais nas trajetórias de carreira de pessoas negras. Com base na Teoria Crítica da Raça e na Psicologia do Trabalhar, analisou 33 estudos publicados entre 2020 e 2025, majoritariamente qualitativos, oriundos sobretudo dos Estados Unidos e do Brasil. A análise temática identificou obstáculos anteriores ao ingresso no mercado, relacionados ao acesso e à escolha profissional, e desafios posteriores à inserção, como …

26.08.2026journal-article

Aging Cell

Timing‐Dependent Clearance of p16‐Positive Cells Mitigates Radiation‐Induced Accelerated Aging

Karla Valdivieso, Melanie Weigand, Daniela G. Costa, Gung Lee, Nick Pirius, Helene Martini, Shivangi Oberai, Christina Inman, Yi Zhu, Thomas von Zglinicki, Sundeep Khosla, Nathan LeBrasseur, João F. Passos, Tamara Tchkonia, James L. Kirkland, Diana Jurk

ABSTRACT Genotoxic stress induced by cancer therapies is increasingly recognized as a driver of accelerated aging in long‐term cancer survivors, yet the mechanisms responsible for the emergence of age‐related dysfunction months to years after treatment remain poorly understood. Here, we use sublethal whole‐body irradiation as a model of systemic genotoxic stress to test whether senescent cells contribute to the progression of post‐therapy age‐related dysfunction and whether the benefits of senescent cell clearance …

26.08.2026journal-article

Campbell Systematic Reviews: Better Evidence for a Better World

Protocol: Emerging Roles and Care Impacts of Geriatric Pharmacists in Outpatient Multidisciplinary Frailty and Geriatric Syndrome Management: A Systematic Review

Ravi Shankar, Fiona Devi, Xu Qian, Amaevia Lim

This is the protocol for a Campbell systematic review. The objectives are as follows: (1) to summarize the current literature on the roles, responsibilities, and care activities of geriatric pharmacists in outpatient multidisciplinary management of frailty and geriatric syndromes; (2) to evaluate the impact of geriatric pharmacist involvement on medication-related outcomes, patient health outcomes, quality of life, and healthcare utilization; (3) to characterize the patient populations, healthcare settings, and mul …

26.08.2026journal-article

Discover Health Systems

A mixed methods exploration of mental health pathways and treatment as usual for young people experiencing depression in the United Kingdom

Siobhan B. Mitchell, Vashti Berry, Juliette Westbrook, Emma Grace Carey, Alice Wickersham, Alice Garrood, Rachel Hayes, Julieta Galante, Husna Hassan Basri, Kristin Liabo, Tamsin Ford

Abstract Epidemiological data indicate that the prevalence of depression among young people (YP) is increasing. Although evidence-based interventions are effective for many, 20 to 40% fail, and relapse is common. This study focused on second-line treatments. Modifying psychological processes that predispose individuals to treatment failure or relapse necessitates the development of interventions, but their evaluation depends on a clear understanding of current practice to enable meaningful comparison and assessment …

26.08.2026journal-article

Journal of Clinical Medicine

Cardio-Oncology in Older Adults: Evidence Gaps, Geriatric Considerations, and Future Directions

Vasiliki Katsi, Lefki Nikolopoulou, Christos Fragoulis, Vasilios Kordalis, Konstantinos Tsioufis, Konstantinos Toutouzas

Cardio-oncology has emerged as a critical discipline addressing cardiovascular toxicities from cancer therapies, yet substantial evidence gaps persist for elderly patients, who represent over 60% of new cancer diagnoses. This narrative review synthesizes the current literature on cardio-oncology challenges in older adults (≥65 years), highlighting underrepresentation in clinical trials, compounded risks from frailty, multimorbidity, and polypharmacy, and the paucity of geriatric-specific guidelines. Older adults ex …

26.08.2026journal-article

Scientific Journal of Intelligent Systems Research

Research on the Renovation and Transformation Strategies of Aging Urban Neighborhoods under the Coupling of AI Assistance and BIM Technology

Linzhi Huang, Tiantian Liu, Zhiqiang Deng, Chenfeng Zhang, Shaofeng Chen

To address fragmented information, coarse-grained decision-making methods, inefficient coordination, and absence of closed-loop feedback in the renewal of aging urban neighborhoods, this paper proposes an AI–BIM integrated renewal strategy. Aging urban neighborhoods are decomposed into five domains: buildings, municipal infrastructure, streets, public spaces, and community governance. A five-layer integration framework is then constructed, vertically spanning the full life cycle-data, design, implementation, and op …

26.08.2026journal-article

Cytotherapy and Longevity

Effects of Antidiabetic Drugs on Longevity and Healthspan: Evidence and Controversies From Glucose-Lowering Therapy to Anti-Aging Intervention

Xuancheng Zhou, Xinguo Hou

Diabetes provides a clinically visible model of accelerated biological aging. Sustained hyperglycemia, insulin resistance, chronic low-grade inflammation, mitochondrial stress, and endothelial injury converge to increase the burden of cardiovascular disease, chronic kidney disease, neurodegeneration, sarcopenia, and frailty, thereby compressing both survival time and years lived with preserved function. For this reason, evaluation of glucose-lowering drugs can no longer be restricted to HbA1c reduction alone. Morta …

26.08.2026journal-article

Journal of Population Ageing

Association of Parental and Own Educational Attainment Versus Intergenerational Mobility with Cognitive Performance in Brazilian Older Adults

Lidia Lack, Natalia Gomes Goncalves

Abstract Background Education is associated with better cognitive performance in later-life. However, the role of intergenerational educational mobility is less studied. We investigated the associations of participants' own educational attainment, the educational attainment of their parents, and educational mobility, with cognitive performance among Brazilian older adults. Methods We used data from the Brazilian Longitudinal Study of Aging. Cognitive assessment used a global cognitive z-score derived from memory, t …

26.08.2026journal-article

Academic Journal of Health Sciences

Workplace healthy-aging promotion in midlife: mental health and Mediterranean-diet gains from a pilot intervention

Asunción María Fernández-Rodríguez, Juan Carlos Rueda-Garrido, Oscar Arrogante, Diana Jiménez-Rodríguez

Introduction: Population aging is reshaping occupational health, as midlife mental health and lifestyle behaviors influence later-life morbidity. This uncontrolled before-after pilot study evaluated whether a multidisciplinary healthy-aging promotion program (nutrition, physical activity, mental health) was associated with changes in physical and mental health among workers from the Spanish chemical industry. Methods: A pilot before-after longitudinal study without a control group in 18 of 29 enrolled workers (62% …

26.08.2026journal-article

npj Aging

Sex differences in the prevalence and incidence of motoric cognitive risk syndrome: a systematic review and meta-analysis

Siyi Sun, Jingru Zhu, Qing Hu, Xiaoke Zhong, Changhao Jiang

Abstract Motoric cognitive risk (MCR) syndrome, a pre-dementia construct combining subjective cognitive complaints with slow gait speed, shows inconsistent sex differences in prevalence and incidence across studies, possibly reflecting differences in gait speed diagnostic criteria rather than biological differences. We conducted a systematic review and meta-analysis (PRISMA 2020; PubMed, Web of Science, Embase, and Scopus; January 2013–March 2026), pooling sex-difference risk ratios (RR, male vs. female) with rando …