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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

Frontiers in Public Health

Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset

Casey D. Xavier Hall, Zhuo Meng, Beth Okantey, Crim Sabuncu, Brittany Lane, Ladanya Ramirez Surmeier, Julia Sheffler, Diana C. Oviedo, Frank Y. Wong, Gabrielle B. Britton, Eugenia Millender

Introduction Cognitive decline is a growing concern in the United States as the population ages. Risk scores such as the Cardiovascular Risk Factors Aging and Incidence of Dementia (CAIDE) have been validated to assess long-term risk for cognitive decline. The existing literature has primarily focused on biological risk factors; however, there is a growing emphasis on integrating psychological and social factors that may contribute to a greater risk of cognitive decline. Methods This study uses a large administrati …

26.08.2026journal-article

Frontiers in Medicine

Diagnostic challenge of GAD65-associated autoimmune encephalitis mimicking post-traumatic complications in an older adult: a case report

Xiuqing Huang, Qile Zhang, Li Huang, Jian Xu

Introduction Glutamic acid decarboxylase 65 (GAD65) antibody-associated autoimmune encephalitis is an uncommon immune-mediated neurological disorder with heterogeneous neuropsychiatric manifestations. Diagnosis is particularly challenging in older adults when symptoms of recent traumatic brain injury (TBI) overlap with structural or metabolic conditions. Case presentation We report a 79-year-old man who developed recurrent headache, progressive confusion, abnormal behavior, poor oral intake, intermittent myoclonic …

26.08.2026journal-article

International Journal of Systematic and Evolutionary Microbiology

Komagataeibacter ossonobensis sp. nov., a novel bacterial cellulose producer isolated from an artisanal Mediterranean acetification

Diogo Neves Proença, Djenabu Candé, Célia Quintas, Bruno Medronho, Anabela Romano

Bacterial strain CS8 T , a novel bacterial cellulose producer, was isolated from a ‘mother of vinegar’ during an artisanal acetification process in Faro, Portugal and characterized. Strain CS8 T stained Gram-negative and formed rod-shaped cells that grew optimally at 30 °C and at pH 5.5–6.5. Phylogenetic analyses based on the 16S rRNA gene placed strain CS8 T within the genus Komagataeibacter in a distinct lineage, showing the highest sequence similarity to Komagataeibacter diospyri (99.86%), Komagataeibacter pirac …

26.08.2026journal-article

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences

Self-perceptions of aging and advance care planning: Longitudinal evidence from the Health and Retirement Study

Rita X Hu, Yifan Lou

Abstract Objectives Advance care planning (ACP) is increasingly conceptualized as a proactive, communication-centered process that supports person-centered care in later life. Although prior research has focused on demographic and clinical predictors, less is known about the psychological factors that shape how individuals engage in planning. Guided by Stereotype Embodiment Theory, this study examined whether self-perceptions of aging (SPA) prospectively predict patterns of ACP engagement. Methods Data were drawn f …

26.08.2026journal-article

International Journal of Molecular Sciences

Aging in Spaceflight, Oxidative Stress, and Microbiome Dysbiosis: A Comprehensive Review

Charles C. Naney, Joseph L. Graves, Scott H. Harrison

The evolutionary theory of aging demonstrates that the force of natural selection declines with age in multicellular organisms. Two population genetic mechanisms are consistent with the evolutionary theory: mutation accumulation and antagonistic pleiotropy. These in turn account for the physiological, cellular, and molecular mechanisms associated with aging. Spaceflight provides an opportunity to examine how organisms physiologically acclimate to environmental conditions. Mitochondria and the gut microbiome are cen …

26.08.2026journal-article

JAMA Network Open

Domain-Specific Cognitive Concordance in Older Married Couples

Hee Won Yang, Ji Won Han, Dae Jong Oh, Bong Jo Kim, Dong Woo Lee, Jeong Lan Kim, Jin Hyeong Jhoo, Joon Hyuk Park, Jung Jae Lee, Kyung Phil Kwak, Seok Bum Lee, Seok Woo Moon, Seung-Ho Ryu, Shin Gyeom Kim, Ki Woong Kim

Importance Spousal similarity in late-life cognition has been reported, but whether concordance differs across cognitive domains remains unclear. Objective To examine whether cognitive concordance among older married couples is domain specific by comparing real couples with demographically and genetically matched control pairs. Design, Setting, and Participants This nationwide, multicenter, community-based cross-sectional study was conducted from January 2019 to December 2020 and included married couples from the K …

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26.08.2026journal-article

Frontiers in Nutrition

Prognostic nutritional index and geriatric nutritional risk index as predictors of in-hospital major adverse cardiovascular events after percutaneous coronary intervention in acute coronary syndrome patients: a multicenter retrospective cohort study

Jun Li, Fachao Shi, Zheng Wang, Caoyang Fang

Objective To evaluate the association between PNI and GNRI with in-hospital MACE after PCI in patients with ACS, and to compare the predictive value of these two nutritional assessment tools. The optimal cutoff values of PNI and GNRI were determined by calculating the maximum Youden’s index based on ROC curve analysis in the training cohort. Methods This multicenter retrospective cohort study included ACS patients who underwent PCI at three hospitals between January 2021 and December 2024. The training cohort consi …

26.08.2026journal-article

Samsun Sağlık Bilimleri Dergisi

THE RELATIONSHIP BETWEEN HEALTH PROGRAM VIEWING MOTIVATION AND TRADITIONAL AND COMPLEMENTARY MEDICINE ATTITUDES AMONG OLDER ADULTS

Naciye Esra Koyuncu, Berna Bayır

Aim: This study was conducted to determine the relationship between the motivation of individuals aged 65 and over to follow health programmes and their attitudes towards conventional and complementary medicine. Method: This cross-sectional and exploratory study was conducted with 176 older adults registered at a family health centre in the province of Konya. Data were collected using the Personal Information Form, the Health Programme Adherence Motivation Scale, and the Attitudes towards Traditional and Complement …

26.08.2026journal-article

Mental Health and Social Inclusion

Loneliness, social support and self-esteem among Vietnamese young people

Nguyen Thi Anh Thu, Tran Viet Hoang, Bui Minh Duc, Le Thi Minh Loan, Nguyen Van Luot, Hoang Thi Thao

Purpose This study aims to examine how perceived social support from friends, family and significant others is associated with loneliness among Vietnamese young people and whether self-esteem explains these associations. Design/methodology/approach A cross-sectional survey was conducted with 996 Vietnamese young people aged 16–30 from Hanoi, Phu Tho, Da Nang and Ho Chi Minh City. Participants completed the UCLA loneliness scale (Version 3), the multidimensional scale of perceived social support and the Rosenberg se …

26.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

AFFECT AS AN ACTIVE METHODOLOGY IN MUSIC THERAPY FOR PEOPLE WITH AUTISM SPECTRUM DISORDER

Vilton Zimmermann de Souza, Nórton Zimmermann de Souza, Gabriel Baldissera de Souza, Rafael Manfro, Elizabeth Ferreira Martinez

Autism Spectrum Disorder (ASD) is characterized by persistent differences in social communication and interaction, associated with restricted or repetitive patterns of behavior and sensory particularities. In this context, music therapy provides relational, expressive, and participatory resources that may foster engagement and communication. This article aims to analyze the role of affect as a structuring element of active methodologies applied to music therapy for people with ASD. A qualitative literature review w …

26.08.2026journal-article

International Journal of Gynecology & Obstetrics

The womb as the cradle of longevity: Perinatal origins of biological aging

Sevim Ozge Ozdemir, Ebru Davutoglu

Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and placental mediation. Evidence from the Dutch Hunger Winter suggests that the timing of gestational exposure—not birth weight alone—might govern programming outcomes. M …

26.08.2026journal-article

Frontiers in Public Health

Associations between physical exercise and aging anxiety among older adults: a serial statistical mediation analysis involving self-efficacy and health anxiety

Wenmin Yu, Guoxi Ye

Background With the acceleration of global population aging, mental health issues among older adults have become increasingly prominent. Aging anxiety, defined as apprehension regarding the aging process and associated physiological, psychological, and social role losses, significantly impacts the quality of life and health of the older adults. Physical exercise has been shown to be associated with better physical and mental health of older adults, yet the theoretical psychological mechanisms underlying their assoc …

26.08.2026journal-article

Multimedia Systems

Augmented reality for remote care: a co-creation approach to supporting older adults and healthcare professionals

Achilleas Achilleos, Elena Kyprianou, Sotiria Moza, Joanna Starosta-Sztuczka, Karol Pecyna, Csaba Kostyal, Gyula Vad

Abstract Augmented Reality (AR) can enhance remote audio/video communication by enabling healthcare professionals to provide clear, intuitive instructions for older adults. AR solutions have proven effective in sectors like surgery and technical maintenance. Nevertheless, their use in the care of older adults remains limited. This paper presents an AR-enhanced audio/video communication service designed and developed by following an iterative, user-centered co-creation approach involving older adults, caregivers, an …

26.08.2026journal-article

Molecules

In Vitro Anti-Aging Properties of a Cetraria islandica Extract: Interest for Skin Care Cosmetics

Anthony Groso, Paul Jabet, Yang Fan, Wang Hua, Hu Yawen, Guo Miao, Richard Daniellou, Guillaume Collet

Skin aging is a major consideration regarding cosmetic skin care. The cosmetic field is seeking new active ingredients able to slow down the appearance of signs of age. Some lichens and more specifically the genus Cetraria s. str. presents an interest as a source of active molecules because it is already being used in traditional and modern medicines. To better evaluate the potential of C. islandica as anti-aging skin care, we investigated some key aspects to protect skin from external aggression and to avoid skin …

26.08.2026journal-article

World Journal of Cardiology

Cardiovascular aging as a modifiable biological process: Mechanisms, clinical phenotypes, and translational opportunities

Qing Liu, Yi-Fei Wang, Yu Geng, Ping Zhang, Ting-Ting Lv

Cardiovascular aging, a primary driver of the increasing prevalence of cardiovascular disease in older adults, involves a complex biological basis beyond mere chronological age. From a geroscience perspective, aging is now understood as a dynamic and potentially modifiable process, believed to be governed by interconnected molecular hallmarks such as cellular senescence, mitochondrial dysfunction, epigenetic remodeling, telomere attrition, and impaired proteostasis. This review synthesizes recent advancements in ag …

26.08.2026journal-article

JMIR Formative Research

Health Care Professionals’ Estimation of Home Spirometry Use Among People With Cystic Fibrosis: Cross-Sectional Study

Aqeem Azam, Andrew M Jones, Rowland J Bright-Thomas, Alex Horsley, Peter J Barry

Abstract Background Home spirometry has been widely adopted in the delivery of cystic fibrosis (CF) care. While existing literature largely supports its feasibility and positive outcomes, behavior around home disease monitoring remains poorly understood. Inaccurate assumptions about home spirometry behavior may affect resource prioritization and influence clinical decisions and follow-up. Objective This study aimed to evaluate health care professionals’ (HCPs’) ability to estimate home spirometry use among people w …

26.08.2026journal-article

Molecules

Multi-Level Evaluation of Antioxidant Activity, Aging-Related Physiological Functions, and Longevity Effects of Nelumbo nucifera Gaertn. Embryo Extract, Pleuropterus multiflorus (Thunb.) Turcz. ex Nakai Stilbene Glycoside, and Pterostilbene

Kuo-Ching Jan, Jung-Chun Tai, Xiao-Zhong Liu, Yu-Mei Li, Mohsen Gavahian

Despite known antioxidant activity, the effects of plant-derived compounds on aging-related physiological functions and mechanisms remain unclear, which necessitates investigation at cellular and organismal levels. To examine whether these compounds can mitigate age-related physiological decline, Nelumbo nucifera Gaertn. (sacred lotus) embryo extract–water-soluble fraction (NEW), stilbene glycoside from Pleuropterus multiflorus (Thunb.) Turcz. ex Nakai (PM-SG), and pterostilbene were investigated through chemical p …

26.08.2026journal-article

Journal of Holistic Nursing

Holistic Nursing Care for People Experiencing Diabetes Burnout: A Theoretical Reflection Using the Tidal Model

Marcelino Maia Bessa, Rodrigo Jácob Moreira de Freitas, Maria Célia de Freitas, Vanessa de Araujo Lima Freire, Lourival Veras de Oliveira, Sherida Karanini Paz de Oliveira

Diabetes burnout is an emerging psychosocial phenomenon characterized by emotional, physical, and mental exhaustion associated with the continuous demands of diabetes management, adversely affecting self-care and wellbeing. This study aimed to develop a theoretical reflection on how the principles of the Tidal Model, interpreted through the lens of holistic nursing, may inform nursing care for individuals experiencing diabetes burnout. This theoretical reflection was based on an analytical and interpretive approach …

26.08.2026journal-article

ACS Earth and Space Chemistry

Increased Viscosity of Submicron Biomass-Burning Organic Aerosol after Photochemical Aging

Katherine R. A. Kolozsvari, Natasha M. Garner, Emily J. Costa, Yanfang Chen, Yiwei Gong, Ryan D. Davis, André S. H. Prévôt, Imad El Haddad, Markus Ammann, David M. Bell, Andrew P. Ault

Abstract Biomass burning (BB) is a major global source of atmospheric aerosols. BB primary organic aerosol (BB-POA) particles vary based on fuel and burning conditions, leading to differences in particle-to-particle composition, even from a single burning event. In addition to BB-POA particles, BB emits volatile organic compounds (VOCs), which can be oxidized to form lower-volatility species that condense onto or react with POA to form secondary organic aerosol (SOA). Aerosol viscosity impacts aging processes by ch …

26.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

EFFECTS OF STRENGTH TRAINING AND WALKING ON FLEXIBILITY, HAND GRIP STRENGTH, AND UPPER AND LOWER LIMB STRENGTH IN ADULTS AND OLDER ADULTS

Paulo Henrique de Sousa Gomes, Hanna Nayane Souza Soares, Maria de Lourdes Machado de Resende Neta, Allyne Kelly Carvalho Farias, Ícaro Soares de Carvalho Pinheiro, Letícia Rebeca Soares Melo, Francisca Islândia Cardoso da Silva, Patrícia Uchôa Leitão Rebouças

O processo de envelhecimento é inerente a todos, fazendo-se necessário pesquisas e discussões para entender os riscos e as limitações que este processo traz a adultos de meia idade e a população idosa. Diante disso, o objetivo desse estudo foi comparar o efeito do treinamento de força e da caminhada na flexibilidade, força de preensão palmar e força de membros superiores e inferiores entre adultos e idosos. Foi realizada uma pesquisa com 25 participantes, divididos em dois grupos, praticantes de treinamento de forç …

26.08.2026journal-article

Life

Arterial Stiffness and Anti-NR2/GluN2 Autoantibodies to N-Methyl-D-Aspartate Receptors as Markers of Vascular Aging and Cognitive Impairment in Arterial Hypertension

Tatiana Safronova, Sofia Mukhanova, Anna Bragina, Aida Tarzimanova, Alexander Ivannikov, Tatiana Vargina, Anna Pokrovskaya, Julia Rodionova, Natalia Druzhinina, Lyubov Vasilyeva, Alexander Cherepanov, Nikolay Dorokhov, Natalia Gureva, Natalia A. Dragomiretskaya, Irakli Zh. Loriya, Valery Podzolkov

Background: Arterial hypertension (HTN) is associated with accelerated vascular aging, cerebral microvascular injury, and cognitive decline. Anti-NR2/GluN2 (NR2) antibodies may be related to N-methyl-D-aspartate receptor (NMDAR)-mediated neuronal-ischemic injury, although their clinical significance in HTN requires further clarification. Objective: The aim of this study was to evaluate cross-sectional associations between arterial stiffness assessed by the cardio-ankle vascular index (CAVI), serum NR2 antibody leve …

26.08.2026journal-article

Geriatrics & Gerontology International

Withholding Oral Anticoagulation at Discharge and Post‐Discharge Stroke and Bleeding Vulnerability in a Predominantly Older Cohort Hospitalized With Acute Heart Failure and Atrial Fibrillation

Jumpei Yamamoto, Keijiro Nakamura, Hiromasa Hayama, Yoshinari Enomoto, Masaya Yamamoto, Hidehiko Hara, Hisao Hara, Yukio Hiroi

ABSTRACT Aim In older adults hospitalized with acute heart failure and atrial fibrillation, bleeding concern often drives withholding of oral anticoagulation at discharge. Whether withholding marks a genuinely lower bleeding‐risk phenotype or residual clinical vulnerability is uncertain. We examined its association with post‐discharge ischemic stroke, major bleeding, and death in a predominantly older cohort. Methods We analyzed a registry of patients hospitalized with acute heart failure and atrial fibrillation. I …

26.08.2026journal-article

The International Journal of Aging and Human Development

Building Student Skills and Belonging as Geroscience and Gerojustice Researchers Through a Longevity and Aging Research Education Program: A Qualitative Analysis

Ambria Crusan, Shavonnye Rath, Paula C. Furey, Joshua D. Guggenheimer, Marcella J. Myers, Katherine A. Campbell

Addressing cumulative health disparities across the lifespan requires a scientific workforce trained at the intersection of geroscience and gerojustice. By integrating holistic academic and social support, an interdisciplinary Longevity and Aging minor, and scaffolded intramural and extramural research mentorship, the Katies for Aging Research and Equity (KARE) Program at St. Catherine University positions students to succeed as future aging researchers. To evaluate student growth, focus group transcripts, written …

26.08.2026journal-article

Journal of Exercise Rehabilitation

Influence of sarcopenia on functional independence and depression in older adults: a cross-sectional study

Tae-Hyun Yoon, Yong-Seok Jee

Differences in physical function, encompassing activities of daily living (ADL) and instrumental activities of daily living (IADL), and depression were evaluated across degrees of sarcopenic severity in older adults. A total of 236 participants (78.72±6.92 years), comprising 101 men and 135 women, were classified into four groups: no sarcopenia (23.7%), possible sarcopenia (26.3%), sarcopenia (28.0%), and severe sarcope-nia (22.0%). Sarcopenic measures included calf girth, grip strength, 5-time chair stand test, an …