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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

Journal of Language, Literature & Social Affairs

Analyzing the Impact of Cyber Harassment, Cyber Stalking Victimization, and Cyber Gender Hate Speech on Social Wellbeing of Female University Students in Sialkot Pakistan

Khadija Shahbaz, Muhammad Umair Ashraf

This study's main objective is to examine how cyber stalking victimization, cyber harassment, and cyber gender hate speech affect female university students' social wellbeing. The goal of this study is to determine how response to these types of online harassment has a negative effect on female students' sense of safety, social interactions, and general well-being in digital contexts. The researcher gathered the data using a survey questionnaire and the quantitative research approach. In this study, a systematic/ra …

29.08.2026journal-article

Responsive Materials

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun

Abstract Ischemic stroke (IS) is one of the primary causes of global mortality and permanent neurological disability, and its clinical treatment is severely constrained by the intricate ischemic pathological cascade and the impermeable blood‐brain barrier (BBB). Cerebral ischemia and reperfusion trigger a series of pathological events including energy depletion, excitotoxicity, calcium overload, oxidative stress and neuroinflammation, accompanied by progressive BBB damage. These pathological processes exacerbate se …

29.08.2026journal-article

European Heart Journal

ESC Guidelines on prevention and rehabilitation in coronary heart disease and current practice: the EUROASPIRE VI survey

David A Wood, Catriona S Jennings, Kornelia Kotseva, Agnieszka Adamska, Iris Erlund, Sandra Ganly, Per-Henrik Groop, Susan Hennessy, Maarten J G Leening, Linda Mellbin, Kausik K Ray, Lars Ryden, Terhi Vihervaara, Victor Aboyans, Ana Abreu, Carlos Aguiar, Karl Andersen, Jolita Badariene, Jan Bruthans, Monika Burzynska, Almudena Castro Conde, Renata Cifkova, Furio Colivicchi, Kairat Davletov, Mirza Dilic, Elena Dimitrova, Maryna Dolzhenko, Vilnis Dzerve, Andrejs Erglis, Zlatko Fras, Baris Gungor, Peter Heuschmann, Piotr Jankowski, Iulia Kulcsar, Nebojsa M Lalic, Seppo Lehto, Dragan Lovic, Aldo P Maggioni, Fabrice MAC Martens, Lampros K Michalis

Abstract Background and Aims This observational study investigated whether patients with coronary heart disease (CHD) in Europe are achieving the standards set by prevention and rehabilitation guidelines. Variability was studied: (i) between countries; (ii) between geographical risk regions; and (iii) attendance at cardiac rehabilitation (CR) with outcomes. Methods Observational study between September 2024- February 2026 in 160 hospitals across 27 countries. Geographical risk regions were defined as high, moderate …

29.08.2026journal-article

Current Signal Transduction Therapy

Multikinase Inhibition as a Therapeutic Strategy for Status Epilepticus: Current Evidence and Future Directions

Vaishnavi B., Asha Nayak, Darshan Gowda L.M., Sunil Kumar Kadiri

Introduction:: Status epilepticus (SE) is a serious neurological emergency defined by prolonged or recurring seizures that frequently do not respond to standard antiepileptic medications. Recent revelations into the molecular underpinnings of SE, including neuroinflammation, oxidative stress, angiogenesis, and disruption of the blood-brain barrier, have stimulated research into targeted therapeutics. Lenvatinib, a multi-kinase inhibitor sanctioned for many cancers, has demonstrated potential neuroprotective and ant …

29.08.2026journal-article

Annals of Pharmacotherapy

Efficacy and Safety of Vonoprazan-Tetracycline Dual Therapy Versus Bismuth-Containing Quadruple Therapy for Helicobacter pylori Eradication: A Systematic Review and Meta-analysis

Amna Amir Jalal, Syeda Samia Fatima, Abdul Wasio, Rohma Zubairi, Sundus Malik, Rutaba Darooj, Sameer Mehmood, Baneen Javed Arain, Ayesha Ashar, Ayesha Arif, Syed Ibad Hussain

Objective: To compare the efficacy and safety of 14-day vonoprazan-tetracycline (VT) dual therapy versus bismuth-containing quadruple therapy (BQT) for Helicobacter pylori eradication. Data Sources: PubMed/MEDLINE, Scopus, Cochrane Library, and Google Scholar were systematically searched from database inception through July 1, 2026, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Search terms included combinations of “ Helicobacter pylori ,” “vonoprazan,” “tetracycline,” “du …

29.08.2026journal-article

International Journal of Research in Medical Sciences

From static to dynamic prosthodontics: digital recording of mandibular function for personalized prosthetic rehabilitation

Rohit Raghavan, Shajahan P. A., Shaman Shalu S. B.

Conventional prosthodontic diagnosis and treatment planning rely extensively on static records such as diagnostic casts, maxillomandibular relationship records, facebow transfers, interocclusal records, and mechanical articulators. Although these methods remain clinically valuable, they provide only a limited representation of the continuously changing relationship between the maxilla, mandible, temporomandibular joints, dentition, and neuromuscular system. Advances in digital dentistry have enabled the acquisition …

29.08.2026journal-article

International Journal of Pattern Recognition and Artificial Intelligence

The Art Therapy for Preschool Children’s Mental Health Based on Artificial Intelligence and Deep Learning

Xiyuan Zhang

This study addressed the limited language expression abilities of rural left-behind preschool children and the limitations of conventional anxiety assessment methods, which primarily rely on parent reports and expert observation. A one-dimensional Convolutional Neural Network (CNN)-Long Short-Term Memory (LSTM) classification model integrating Electrocardiogram (ECG) and Electrodermal Activity (EDA) signals was developed. A total of 160 rural left-behind preschool children aged 3–6 years were enrolled. At the parti …

29.08.2026journal-article

International Journal of Research in Medical Sciences

Exploring the relationship between stress, sleep quality, mobile phone usage and physical activity among physiotherapy students: a survey study

Arshpreet Singh, Pankajpreet Singh, Supreet Bindra, Shavez Mansoori

Background: Physiotherapy students are frequently exposed to academic, clinical, and personal stressors that may affect their sleep quality, smartphone usage patterns, and physical activity levels. The aim of the study is to explore the relationship between stress, sleep quality, smartphone addiction, and physical activity among physiotherapy students. Methods: A cross-sectional correlational study was conducted among 300 physiotherapy BPT and MPT students. Data were collected using the SSI, PSQI, SAS-SV and IPAQ-S …

29.08.2026journal-article

Mathematics

Can IL-10 Inhibitor Therapy Alongside MDT Enhance Leprosy Treatment? A Comprehensive Mathematical Study

Salil Ghosh, Huina Zhang, Satyajit Mukherjee, Xianbing Cao, Amit Kumar Roy, Priti Kumar Roy

Leprosy is characterized by complex biological and cellular interactions, driven primarily by the interplay between Th1 and Th2 cells. In this study, we develop a deterministic mathematical model to investigate the interactions among healthy and infected Schwann cells, M. leprae bacteria, and Th1–Th2 immune responses. The positivity and boundedness of the proposed five-dimensional system are established, and the disease persistence condition is characterized in terms of the basic reproduction number (R0). The exist …

29.08.2026journal-article

Archiv Euromedica

SOTATERCEPT AS A POTENTIAL DISEASE-MODIFYING THERAPY IN PULMONARY ARTERIAL HYPERTENSION: A NARRATIVE REVIEW

Aleksandra Kamińska, Maria Miller, Aleksandra Pakulska, Aleksandra Błoch, Natalia Rządzińska

Background Pulmonary arterial hypertension (PAH) is a progressive and potentially fatal disease characterized by increased pulmonary vascular resistance, pulmonary vascular remodeling, and right ventricular failure. To date, therapy has relied mainly on vasodilatory action and has not sufficiently improved patients' long-term prognosis. There is therefore a need for therapies targeting pathways involved in disease progression and pulmonary vascular remodeling. Aims To summarize current data on the mechanism of acti …

29.08.2026journal-article

Denta: Jurnal Kedokteran Gigi

Effect of Low-Level Laser Therapy on The Number of Lymphocytes in Oral Ulcer Healing of Immunosuppressed Rats

Reiska Kumala Bakti, Desiana Radithia, Nurina Febriyanti Ayuningtyas, Fatma Yasmin Mahdani, Ghinaya Shaliha Nursaida Nisa

Background: Glucocorticoid-induced immunosuppression disrupts cellular immune responses, including lymphocyte function, and delays oral traumatic ulcer healing. Low-Level Laser Therapy (LLLT) offers an alternative for healing traumatic oral ulcers in immunosuppressed patients. Objective: To analyze the effect of 650 nm LLLT on the number of lymphocytes in traumatic ulcer tissue of immunosuppressed Wistar rats. Materials and Methods: Experimental laboratory study with a randomized post-test-only control group design …

29.08.2026journal-article

Journal of Neuro-Oncology

Radiological response of primary central nervous system lymphoma after corticosteroid therapy and its predictive value on overall survival: a multicenter study

Florian Scheichel, D. Pinggera, T. Rossmann, B. Popadic, S. Aspalter, V. Schön, A. Woehrer, M. M. Dorostkar, C. Dorfer, C. F. Freyschlag, F. Marhold

Abstract Background Primary Large-B-Cell Lymphoma of the CNS (PCNS-LBCL) is a rare, aggressive tumor often sensitive to corticosteroid therapy (CST). This multicenter study investigated the spectrum of radiological responses to routine CST and evaluated its impact on patient prognosis. Methods The researchers utilized a prospective cohort of 18 patients for volumetric MRI analysis and a combined prospective-retrospective cohort of 31 patients for 2D tumor analysis. Patients received CST post-biopsy, with follow-up …

29.08.2026journal-article

Journal of Neuropsychology

Enhancing social and linguistic skills in children with autism: A semi‐randomized controlled clinical trial of a virtual reality‐based communicative rehabilitation programme

Hassnaa O. Mohammed, Ehab M. Eid, Enas Rady Younes

Abstract Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication, and conventional therapies often struggle to facilitate the generalization of these skills to real‐world settings. This study aimed to determine the effectiveness of a virtual reality (VR)‐based communication rehabilitation intervention as a supplement to conventional treatment for improving the linguistic and social communication skills of Arabic‐speaking Egyptian children with ASD. A clinical trial with a pret …

29.08.2026journal-article

REiLA : Journal of Research and Innovation in Language

Interactional Pragmatics of Directive Speech Acts in Hypnotherapy: A Qualitative Case Study of a Mental-Block Client

Suci Ayu Kurniah, Gusnawaty Gusnawaty, Lukman Lukman, Ikhwan M. Said

Language serves as a therapeutic instrument in hypnotherapy, yet how directive speech acts are strategically organized to facilitate emotional regulation and behavioral transformation in naturally occurring sessions remains underexplored. Existing research predominantly emphasizes clinical efficacy and psychological outcomes, while micro-pragmatic analyses of how therapists linguistically construct suggestion, authority, and client agency across session phases remain limited, particularly in non-English therapeutic …

29.08.2026journal-article

Experimental Physiology

Cardiometabolic effects of contrast therapy: A systematic review

Veerle de Haan, Guy Plasqui, Hannah Pallubinsky

Abstract The rising prevalence of overweight and obesity, together with associated cardiometabolic disorders, underscores the need for additional strategies alongside established interventions. The growing popularity of contrast therapy – alternating exposure to heat and cold, a practice common in traditional Finnish sauna bathing – has prompted interest in its potential cardiovascular and metabolic health benefits. This systematic review outlines the acute and chronic effects of contrast therapy on cardiometabolic …

29.08.2026journal-article

Nutrients

Phase-Specific Nutritional Therapy in Critical Illness: When Protein May Help and When It May Harm, from Acute Metabolic Adaptation to Post-ICU Recovery

Mircea Stoian, Adina Stoian, Claudia Bănescu, Sergio Rares Bandilă Bandilă, Alina Danilesco, Hajnal Finta, Leonard Azamfirei

Background: Nutritional support in critically ill patients remains one of the most debated aspects of intensive care medicine. Although international guidelines have long recommended early nutritional support with progressive protein delivery, recent clinical evidence has questioned the benefit of aggressive early calorie and protein provision during the acute phase of critical illness, highlighting the need for phase-adapted nutritional strategies. Methods: This narrative review summarizes current evidence on indi …

29.08.2026journal-article

Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics

An Explainable XGBoost Framework for Mortality Prediction in People Living with HIV Receiving Antiretroviral Therapy

Ni Putu Likayuni Viona, Ngakan Nyoman Kutha Krisnawijaya, Desak Nyoman Widyanthini

Mortality remains an important concern among people living with HIV (PLHIV) receiving antiretroviral therapy (ART), particularly when high-risk patients are not identified early. This study presents an explainable mortality prediction approach based on an optimized Extreme Gradient Boosting (XGBoost) classifier. A retrospective dataset containing 393 clinical records was analyzed. Before model training, duplicate entries were removed, missing values were imputed, categorical variables were encoded, and class imbala …

29.08.2026journal-article

Journal of Clinical Medicine

Effects of Metformin Monotherapy Versus Metformin Plus SGLT-2 Inhibitor Therapy on Molecular and Cellular Inflammatory Markers in Patients with Newly Diagnosed Type 2 Diabetes Mellitus

Bennur Esen, Damla Yildiz, Ahmet Engin Atay

Background/Objectives: Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by insulin resistance and chronic low-grade inflammation. Tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), the systemic immune-inflammation index (SII), and the systemic inflammation response index (SIRI) are important markers used to evaluate inflammatory status in T2DM. This study aimed to compare inflammatory and metabolic parameters between patients receiving metformin monotherapy and those receiving metformin …

29.08.2026journal-article

BMC Health Services Research

National trends in inpatient rehabilitation utilization among patients with sepsis in Japan: a nationwide cohort study from 2010 to 2020 by the Japan Sepsis Alliance (JaSA) study group

Taro Imaeda, Yusuke Kawamura, Takehiko Oami, Tatsuro Yokoyama, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Yutaka Umemura, Asako Matsushima, Kiyohide Fushimi, Taka-aki Nakada

Abstract Background Rehabilitation is increasingly recognized as an essential component of recovery for patients with sepsis. However, the real-world delivery of rehabilitation services for sepsis has not been characterized at a national level. This study aimed to evaluate temporal trends and patterns in the utilization and delivery of inpatient rehabilitation among patients hospitalized with sepsis in Japan. Methods This nationwide retrospective cohort study used the Japanese Diagnosis Procedure Combination databa …

29.08.2026journal-article

Archives of Current Research International

Herbal Therapy in the Management of Polycystic Ovary Syndrome: A Critical Narrative Review of Mechanistic Claims, Clinical Evidence and Translational Barriers

Ayushi Masih, V. Paul

Polycystic ovary syndrome, still widely described as polycystic ovarian disease in parts of South Asia, is the most common endocrine and metabolic disorder affecting women of reproductive age. Its management remains symptom directed, and dissatisfaction with conventional pharmacotherapy has helped make herbal preparations one of the most frequently self-administered adjuncts in this population. The purpose of this critical narrative review is to evaluate what the accessible literature can and cannot establish about …

29.08.2026journal-article

Antibiotics

Specialty-Related Differences in Adherence to Antibiotic Therapy Guidelines for Infective Endocarditis in Older Patients

Lidvine Godaert, Claire Roubaud-Baudron, Emmanuel Forestier, Moustapha Dramé, the ENDOLA Study Group

Background/Objectives: Infective endocarditis (IE) is a condition with complex management, and several guidelines exist to guide clinicians. Adherence to these recommendations varies and could even be described as poor. The aim of this study was to determine whether the medical specialty of the unit that initiated first-line treatment for IE was associated with risk factors of non-adherence to the 2015 ESC treatment guidelines in a population of patients aged 75 years and over. Method: We analysed data from patient …

29.08.2026journal-article

Mini-Reviews in Medicinal Chemistry

Mitochondrial Dynamics and Bioenergetic Reprogramming: Drivers of Cancer Therapy Resistance

Varsha Johariya, Vaibhav Singh, Rakesh Kore, Santosh Kumar, Ravichandran Veerasamy, Amit K. Tiwari, Harish Rajak

Abstract: Mitochondria, often referred to as the powerhouses of the cell, play a pivotal role in maintaining cellular homeostasis through the regulation of energy production, redox balance, and apoptosis. Recent evidence highlights the significance of mitochondrial dynamics, fusion, fission, biogenesis, and mitophagy, enabling cells to adapt to changing physiological and environmental conditions. Dysregulation of these dynamic processes alters mitochondrial function, promoting metabolic reprogramming, evasion of ap …

29.08.2026journal-article

Journal of the Pediatric Infectious Diseases Society

Determinants for antibiotic therapy less or more than 7 days in pediatric oncology patients with bacteremia: a global multicenter retrospective study

Griselda Escobedo-Melendez, Joseph Wardell, Parthasarathi Bhattacharyya, Joanna Acebo, Riyadi Adrizain, Bambang Ardianto, Martha Avilés, Maribel Baquera Arteaga, Shymaa Elsayed, Dolores Freire Jijon, Samanmalee Gunasekara, Asher Hancock, Hilda Hernandez, Kim Hoa, Reham Khedr, Yanina Lagala, Jacqueline Levy, Sergio Licona, Medalit Luna, Alejandra Nava, Genara Santana, Eneida Sánchez Medina, Meenakshi Devidas, César Villegas, Sheena Mukkada

Abstract Background Randomized trials support the non-inferiority of short-course (≤7 days) antibiotic therapy for bacteremia; however, these studies commonly exclude immunocompromised patients. Shorter regimens may reduce drug toxicity while optimizing resource utilization and patient quality of life. Evidence to guide treatment duration in immunocompromised children remains limited. Methods We conducted a global, multicenter retrospective study of bacteremia in children with cancer ≤18 years old treated between A …

29.08.2026journal-article

Journal of the Pediatric Infectious Diseases Society

Impact of Fidaxomicin De-Restriction on Clostridioides difficile Episodes in Hospitalized Pediatric Cellular Therapy Patients

Andrew Karnaze, Darra Drucker, Regina Orbach, Leila C Posch

Abstract Background Pediatric patients undergoing cellular therapy (CT) with hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell (CAR-T) therapy are vulnerable to Clostridioides difficile infection (CDI). Recent guidelines recommend fidaxomicin treatment for first and recurrent uncomplicated CDI episodes in this population, though pediatric real-world data is limited. Fidaxomicin is narrower spectrum, dosed less frequently, and can be used for shorter durations versus enteral vancomycin. In …