EUVIMEDEuropean Health Evidence
Uhr 10/10Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Alter & Demenz · Seite 45

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences

Factors shaping social participation among community-dwelling older adults in China: A mixed-methods study from the perspectives of older adults and community workers

Yufan Yang, Weihang Xu, Mingyao Sun, Meng Zhao, Huanhuan Luo, Jingyi Liu, Lillian Hung, Zhiwen Wang

Abstract Objectives Guided by the Social Ecological Model (SEM), this study aimed to examine multilevel influences on social participation among community-dwelling older adults from the perspectives of older adults and community workers. Methods A convergent parallel mixed-methods design was used. The quantitative component included 641 community-dwelling older adults from five communities in Beijing, China. The qualitative component involved semi-structured interviews with 18 older adults and 14 community workers. …

26.08.2026journal-article

Diabetology

Limitations of a Recent Study on Insulin Pen Needle Preferences in People with Diabetes. Comment on Gentile et al. Enhancing Insulin Therapy Adherence Through Technology: Which Needles Do People with Diabetes Prefer? Diabetology 2026, 7, 56

David C. Klonoff, Mandy M. Shao, Agatha F. Scheideman

We read with interest a recent article in Diabetology titled “Enhancing Insulin Therapy Adherence Through Technology: Which Needles Do People with Diabetes Prefer [...]

1 Zitationen
26.08.2026journal-article

Frontiers in Public Health

Effects of exercise interventions on fall-related injuries in community-dwelling older adults: an updated systematic review and meta-analysis

Beihai Ge, Jinsong Luo, Xiaofeng Cheng, Deng Wang, Renming Liu, Xianhui Liao

Background Exercise interventions are widely recommended for preventing falls in older adults in the community; however, existing evidence regarding their effectiveness in reducing fall-related injuries remains inconsistent. This updated systematic review and meta-analysis aimed to assess the impact of exercise interventions on fall-related injuries in older adults in the community. Methods PubMed, Embase, Cochrane Library, and CINAHL databases were systematically searched from inception to April 2, 2026. Included …

26.08.2026journal-article

Journal of the American Geriatrics Society

Driving Navigation in Older Adults Across the Alzheimer's Disease Continuum

Yiqi Zhu, Julie K. Wisch, Ziqiao Jiao, David C. Brown, Noor Al Hammadi, Tammie L. S. Benzinger, John C. Morris, Beau M. Ances, Ganesh M. Babulal

ABSTRACT Background and Objectives To examine whether time from amyloid positivity (amyloid time), a continuous measure of biological Alzheimer's disease (AD) progression, is associated with differences in navigation‐related driving behaviors among older adults. Methods This longitudinal cohort study was drawn from the DRIVES participants who had at least one PET Pittsburgh compound‐B (PiB) scan. AD timeline was assessed using amyloid time, estimated with the Sampled Iterative Local Approximation (SILA) approach. S …

26.08.2026journal-article

Works of the Faculty of Agriculture and Food Sciences University of Sarajevo

CELIAC DISEASE – A CHALLENGE FOR PEOPLE AFFECTED IN THE HERZEGOVINA-NERETVA CANTON

Robert Kepić, Emina Ademović, Mladenka Vukojević, Jasna Avdić

Celiac disease is a chronic disorder of the digestive system caused by the intake of gluten in genetically predisposed individuals. It is characterized by a high prevalence and often delayed diagnosis due to nonspecific symptoms, such as chronic diarrhea, vomiting, loss of appetite, fatigue, and anemia, which are frequently pushed aside, or misattributed to other conditions. The disease often occurs in association with other autoimmune diseases. Having in mind a complex administrative structure of Bosnia and Herzeg …

26.08.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Possible osteosarcopenia is associated with loss in intrinsic capacity and early cognitive deficits: a longitudinal study of older adults in Singapore

Vanessa Jean Wen Koh, Khong Thi Minh Thu, Lakkhina Troeung, Rahul Malhotra, Dheeraj Jha, Anitha D Praveen, Yi Xing Liu, Benedikt Helgason, Navrag B Singh, Angelique Wei-Ming Chan

Abstract Background Osteosarcopenia is linked to frailty, falls, fractures, and mortality. It may impair intrinsic capacity (IC), with emerging evidence especially pointing to its relationship with cognition capacity. We determined the prevalence and characteristics of persons with possible osteosarcopenia in older adults and examined its association with IC, with a focus on cognition. Methods 2,291 participants were recruited through a national household survey of older adults in Singapore. Socio-demographic, heal …

26.08.2026journal-article

Exercise Science

Effects of High-Intensity Interval Training Versus High-Intensity Circuit Training on Airflow Limitation in Older Adults with Pre-COPD: A Pilot RCT

Eun-Ah Jo, Soo-Jin Lee, Ki Uk Kim, Myung-Jun Shin, Tae-Sung Park, Jung-Jun Park

PURPOSE: Pre-COPD, characterized by mild airflow limitation, represents a critical window for preventing progression to chronic obstructive pulmonary disease (COPD). This pilot randomized controlled trial examined the effects of high-intensity interval training (HIIT) versus high-intensity circuit training (HICT) on pulmonary function in older adults with pre-COPD.METHODS: Twenty older men aged 60-75 years with pre-COPD, defined as normal or near-normal FEV1 with symptoms, risk factors, and mild airflow limitation …

26.08.2026journal-article

Sociological Perspectives

Authentically, Yet Situationally ‘Latinx’ and ‘Latine’: How Gender-Expansive People of Latin American Descent Navigate Panethnic Labels

Luis Edward Tenorio, David Munoz, Stephanie Granobles

The present study draws from interviews with 54 U.S.-born gender-expansive people of Latin American descent to examine how they understand, identify with, and use ‘Latinx’ and ‘Latine’ relative to ‘Hispanic’ and ‘Latino/a’. We find many not only identified with ‘Latinx’ and ‘Latine’ among labels like ‘Hispanic’ and ‘Latino/a’, they also described ‘Latinx’ and ‘Latine’ to feel the most authentic. Participants also reported the political and policy climate in the U.S. around gender-expansive individuals contributed t …

26.08.2026journal-article

Corporate and Business Strategy Review

Emotional intelligence in leadership: People-centered practices and cultural transformation. The case of Microsoft strategy

Ioanna Dimitrakaki

Research on emotional intelligence (EI) and leadership has expanded considerably in recent years. However, limited attention has been given to how emotionally intelligent leadership may shape people-centered organizational cultures and adaptive workplace practices (Goleman, 1998; López-Cabarcos et al., 2019). This study examines how EI-informed leadership may contribute to cultural transformation, employee engagement, and organizational adaptability within contemporary organizations. The paper focuses on Microsoft …

26.08.2026journal-article

Nature Communications

Deep learning aging marker from retinal images unveils sex-specific clinical and genetic signatures

Olga Trofimova, Leah Böttger, Sacha Bors, Yating Pan, Bart Liefers, Jose D. Vargas-Quiros, Victor A. de Vries, Michael J. Beyeler, David M. Presby, Dennis Bontempi, Janna Hastings, Caroline C. W. Klaver, VascX Consortium, Ciara Bergin, Bogdan Draganski, Adham Elwakil, Györgyi V. Hamvas, Ilaria Iuliani, Ihor Kuras, Ilenia Meloni, Sofia Ortin Vela, Ian Quintas, Marc Schindewolf, Reinier O. Schlingemann, Mattia Tomasoni, Sven Bergmann

Abstract Retinal fundus images offer a non-invasive window into systemic aging. Here, we fine-tune a foundation model (RETFound) to predict chronological age from color fundus images in 71,343 participants from the UK Biobank, achieving a mean absolute error of 2.85 years. The resulting retinal age gap, i.e. the difference between predicted and chronological age, is associated with cardiometabolic traits, inflammation, cognitive performance, all-cause mortality, dementia, cancer, and incident cardiovascular disease …

26.08.2026journal-article

Psychogeriatrics

Internal Consistency, Construct Validity and Incremental Explanatory Power of the Action Observation Sheet‐B ( AOS ‐B) for Dementia Caregiver Burden and Clinical Severity

Reiko Hashimoto, Daisuke Sumita, Takanori Senoo, Yumeno Furukawa, Eiji Ikeda, Akira Tamai, Takashi Uehara

ABSTRACT Background Although the behavioral Action Observation Sheet‐B (AOS‐B) addresses the clinical limitations, patient anxiety and caregiver biases of traditional dementia assessments, evidence regarding its incremental explanatory power remains insufficient. Using real‐world clinical data, this study evaluated the 47‐item AOS‐B's internal consistency, validity and independent contribution to explaining caregiver burden. Methods We retrospectively analysed data from 107 patients with different dementia subtypes …

26.08.2026journal-article

Frontiers in Sociology

Delayed academic consolidation and active aging in European academia: a collaborative autoethnography of migrant women

Mihaela Vancea, Noemí Duran-Salvadó, Valeria De Ormaechea-Otarola, Carolina Quirós-Domínguez

Introduction Migrant women's opportunities for active aging, understood through the World Health Organization framework of health, participation, and security, are shaped by cumulative inequalities across the life course. In European higher education, migrant women academics often experience delayed academic consolidation through trajectories marked by precarious employment, disrupted institutional and relational ties, constrained recognition, and normative expectations that privilege linear and uninterrupted caree …

26.08.2026journal-article

Reproduction

Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate ovarian aging by inhibiting ferroptosis

Chia-Jung Li, Li-Te Lin, Pei-Hsuan Lin, Boyang Wang, Zhi-Hong Wen, Kuan-Hao Tsui

Abstract Ovarian aging is characterized by a decline in oocyte quantity and quality, often driven by oxidative stress and cellular damage. Human umbilical cord mesenchymal stem cell-derived exosomes (hUC-MSC-Exos) have emerged as a potent cell-free therapy for regenerative medicine. In this study, Female mice with early ovarian aging (31-33 weeks; n = 8 per group) received 10 intraperitoneal injections of hUC-MSC-Exos (240 µL/dose, 6.5 × 10¹⁰ particles/mL) over two weeks. Ovarian function, follicular development, D …

26.08.2026journal-article

Frontiers in Public Health

Effects of Health Qigong on quality of life, physical function, and mental health in older adults: a systematic review and meta-analysis of randomized controlled trials

Shi-han Liang, Ming-yuan Zhao, Si-min Huang, Qing-Fa Dou, Ya-kai Zhang

Background Health Qigong is widely used for health promotion in older adults. This study aimed to systematically evaluate its effects on physical function, psychological well-being, and quality of life (QoL), alongside the moderating effects of intervention characteristics. Methods Seven databases were systematically searched (up to May 2025). Twenty-two randomized controlled trials involving 1,791 older adults were included. Risk of bias was assessed using Cochrane RoB, and meta-analyses were performed using RevMa …

26.08.2026journal-article

Nature Aging

Cytotoxic CD4+ T cells induce age-associated myelopoiesis through CCL5–CCR5 signaling

Enrique Gabandé-Rodríguez, Gonzalo Soto-Heredero, Elisa Carrasco, Carlos Anerillas, José Ignacio Escrig-Larena, Jorge Martínez-Cano, Sandra Delgado-Pulido, Isaac Francos-Quijorna, Gabriela Desdín-Micó, Tatiana Smirnova, Manuel M. Gómez de las Heras, Álvaro Fernández-Almeida, Alice Leandri, Andrea Cugurra, Eva María Blanco, Elia Winand-Osete, Pablo Ramírez-Ruiz de Erenchun, Virginia Zorita, Camilla Bean, Valentin Basset, Françoise Solly, Amanda Garrido, Rafael de Cabo, Santos Mañes, Manolis Pasparakis, Matteo Iannacone, César Cobaleda, Olaia Naveiras, Myriam Gorospe, María Mittelbrunn

Abstract Age-associated hematopoietic skewing results in an increase in the neutrophil-to-lymphocyte ratio, which serves as a strong predictor of all-cause mortality in older adults, although its causes are incompletely understood. Here we show that cytotoxic CD4 + T lymphocytes accumulate in the bone marrow of mice during aging and induce myelopoiesis, increasing the neutrophil-to-lymphocyte ratio. T cell receptor-dependent induction of mitochondrial stress and activation of STING upregulates the chemokine CCL5 in …

26.08.2026journal-article

HIV Medicine

Medication burden and prescribing quality in older people living with HIV : Associations with quality of life

Abdulkadir Sonkaya, Nurgül Ceran, Seniha Şenbayrak, Asuman Inan, Serpil Erol, Recep Balik, Vahibe Aydin Sarikaya

Abstract Objectives To determine the prevalence of polypharmacy, drug–drug interactions (DDIs), potential prescribing omissions (PPOs) and potentially inappropriate medications (PIMs) among people living with Human Immunodeficiency Virus (HIV) aged ≥50 years and to evaluate their association with quality of life. Methods This cross‐sectional analytical study was conducted between March and May 2025 at a tertiary infectious disease clinic. A total of 141 people living with HIV aged ≥50 years who were receiving antir …

26.08.2026journal-article

Food Frontiers

Fucoxanthin Attenuates Hepatic Damage in a d ‐Galactose‐Induced Accelerated Aging Mouse Model: Insight Into Underlying Mechanisms

Han‐Ni Wei, Cheng‐Yu Yang, Hui Li, Shi‐Xiang Wu, Qing‐Yan Zou, Yan Zheng, Kazuo Miyashita, Yu‐Hong Yang, Lei Du

ABSTRACT The global population is aging rapidly, and aging‐related hepatic damage poses a significant public health challenge. This study aimed to investigate the protective effects and mechanisms of fucoxanthin (Fx), a marine carotenoid, against hepatic damage in a d ‐galactose ( d ‐gal)‐induced accelerated aging mouse model. Accelerated aging was induced by daily intraperitoneal injection of 400 mg/kg d ‐gal for 12 weeks, during which the Fx groups received daily gavage of Fx at 50 and 100 mg/kg. The results demo …

26.08.2026journal-article

Research on Aging

Volunteering Experience and Intentions Among Older Adults in Italy: Evidence From a Large Quota Sample

Giovanni Telesca, Chia-Shuan Chang, Dina L. G. Borzekowski

The present study investigates volunteering experience and intentions in a large quota sample of older Italian adults aged 60–74 stratified by geographic area and sex (N = 700), focusing on sociodemographic factors, Self-Determination Theory (SDT), and the Theory of Planned Behavior (TPB). Results showed that 35.1% of respondents engaged in formal volunteering in the 12 months prior to the study. Using logistic regressions, we found that past participation is significantly associated with higher education and incom …

26.08.2026journal-article

Journal of Interpersonal Violence

Association of Chronic Pain and Loneliness With Abusive Behaviors Toward Family Members and Older Adults: A Population-Based Cross-Sectional Study in Japan

Naoki Mizunuma, Keiko Yamada, Takashi Kimura, Yutaka Ueda, Takahiro Tabuchi, Kunihiko Kurosaki

Chronic pain is associated with mood dysregulation, irritability, and impaired emotion regulation. However, population-based evidence linking chronic pain to abusive behaviors toward older adults remains limited. This study examined (a) the prevalence of verbal and physical abusive behaviors toward family members and older adults according to chronic pain status and (b) the independent and joint associations of chronic pain history and loneliness with these behaviors. We analyzed pooled cross-sectional data from 39 …

26.08.2026journal-article

Modern Therapy in Psychiatry and Neurology Journal

The mosaic of older mental disorders

Nataliya Petrova

The review provides statistical data on the prevalence of psychiatric disorders of various etiologies in elderly patients. The variants of clinical comorbidity are described and recommendations for safe pharmacotherapy are given. Special attention is paid to the original antipsychotic tiaprid (Tiapridal®, Sotex), which is used to correct behavioral disorders in mental disorders and organic lesions of the central nervous system. Clinical targets for tiaprid are aggression, irritability, and psychomotor agitation. Th …

26.08.2026journal-article

Frontiers in Immunology

Superior outcomes with offspring B-leader-matched haploidentical versus older matched sibling donors in AL/MDS patients aged ≥40 years

Yujun Wei, Jingwen Tang, Ruoling Yang, Yangliu Shao, Songhua Luan, Lu Wang, Lili Wang, Fei Li, Yongli Wu, Kun Qian, Bo Peng, Haoyang Zhang, Dongxue Ge, Yu Fang, Liuqing Huang, Qingyang Liu, Liping Dou, Daihong Liu

Introduction With advancing safety profiles in allogeneic hematopoietic stem cell transplantation (allo-HSCT), determining whether HLA-matched siblings remain the optimal donor choice for older adults (≥40 years) and whether haploidentical-HSCT demonstrates superior survival outcomes have become pivotal focuses in transplantation research. Methods The goal of this study was to explore the efficacy of haploidentical or matched sibling allo-HSCT in patients over the age of 40 years with acute leukemia (AL) and myelod …

26.08.2026journal-article

Journal of Immigrant and Minority Health

Biosociodemographic, Anthropometric, and Laboratory Profiles Associated with the Risk of Developing Chronic Kidney Disease Among Older Adults Living in Quilombola Communities: A Cross-sectional Study

Edison Vitório de Souza Junior, Randson Souza Rosa, Edson Zangiacomi Martinez, Lucas Brasileiro Lemos, Gisele da Silveira Lemos, Isleide Santana Cardoso Santos, Jaine Kareny da Silva Alves, Sávio Luiz Ferreira Moreira, Felix Salvador Chavane, Namie Okino Sawada, José de Bessa Junior

Abstract To investigate the association between biosociodemographic, anthropometric, and laboratory factors and the risk of chronic kidney disease among older adults living in Quilombola communities, as well as to evaluate the discriminatory performance of these indicators in predicting renal risk. A cross-sectional study was conducted involving 120 Quilombola older adults aged ≥ 60 years. Fisher exact test, Student t test, Mann–Whitney test, linear regression analysis, and ROC curve analysis were used to assess th …

26.08.2026journal-article

Frontiers in Aging Neuroscience

DTI-ALPS index and cognitive impairment in cerebral small vessel disease: a systematic review and meta-analysis

Xiao-xue Zeng, Ming-xi Xu, Xia He, Xia-lian Huang, Ying-ying Yang, Feng-le Mao, Fu-li Qin, Yan-qiu Wang

Objective The diffusion tensor image analysis along the perivascular space (DTI-ALPS) index is a non-invasive diffusion tensor imaging-based metric proposed to reflect glymphatic processes. This meta-analysis aimed to evaluate the association of the DTI-ALPS index with cerebral small vessel disease (CSVD) and CSVD-associated cognitive impairment. Methods This meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eight databases wer …

26.08.2026journal-article

Frontiers in Public Health

Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset

Casey D. Xavier Hall, Zhuo Meng, Beth Okantey, Crim Sabuncu, Brittany Lane, Ladanya Ramirez Surmeier, Julia Sheffler, Diana C. Oviedo, Frank Y. Wong, Gabrielle B. Britton, Eugenia Millender

Introduction Cognitive decline is a growing concern in the United States as the population ages. Risk scores such as the Cardiovascular Risk Factors Aging and Incidence of Dementia (CAIDE) have been validated to assess long-term risk for cognitive decline. The existing literature has primarily focused on biological risk factors; however, there is a growing emphasis on integrating psychological and social factors that may contribute to a greater risk of cognitive decline. Methods This study uses a large administrati …