EUVIMED Themenbrowser · Alter & Demenz · Seite 42
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Nutrients
Metabolic syndrome (MetS) represents one of the major public health challenges of our time [...]
Fire and Materials
ABSTRACT Cables are laid tightly in the tunnel, which are an important part of modern power transmission infrastructure. Large power transmission and cable aging can cause cable fires easily, and high fire smoke temperature threatens the stability of tunnel structure, meanwhile smoke toxicity causes evacuees poisoning in the tunnel. The combustion performance including the ignite time (TTI), heat release rate (HRR), critical heat flux, fire performance index (FPI), fire growth index (FGI), and smoke production abou …
Dementia
Caring for a parent with dementia constitutes a profound relational and existential transition for adult children, extending beyond functional caregiving demands to processes of identity negotiation and reconstruction. Although extensive research has documented caregiver burden, psychological distress, and health consequences in dementia caregiving, comparatively little attention has been devoted to the narrative mechanisms through which caregivers sustain a coherent sense of self. Drawing on narrative identity the …
Cells
Aging mesenchymal stem/stromal cells (MSCs) lose regenerative capacity as redox imbalance, mitochondrial damage, defective organelle quality control and chronic inflammation converge. Yet these processes are commonly considered in isolation, obscuring whether damaged mitochondrial cargo reaches lysosomes and is ultimately degraded. Here, we define mitochondria–lysosome quality flux (MLQF) as an author-proposed, evidence-graded framework that tracks mitochondrial damage from recognition and sorting through lysosomal …
PLOS Digital Health
Mental health smartphone applications have become widely available for self-management and support, offering young people new pathways for help-seeking. Despite their increasing popularity, little is known about how app accessibility, content, and features vary across countries, languages, and cultural contexts. This study aimed to systematically examine these differences by drawing on data from the available app stores. Both the Apple App Store and Google Play Store were searched across seven European countries (C …
Frontiers in Aging
Background Approximately one in three adults aged 65–74 years reports hearing difficulty, including age-related hearing loss (AHL, presbycusis). The C57BL/6 mouse is widely used in preclinical AHL research because it develops AHL relatively early. Calorie restriction (CR) attenuates AHL and improves healthspan and longevity in this strain. A recently developed transgenic C57BL/6 mouse expressing naked mole-rat hyaluronan synthase 2 ( nmrHas2 ), which produces very high molecular mass hyaluronan (vHMM-HA), also exhi …
Aging Cell
ABSTRACT The global prevalence of aging and age‐related diseases has increased markedly in recent decades due to extended life expectancy and a growing aging population, posing substantial medical and social burdens. Multiple strategies, including metabolic modulation (e.g., physical exercise, calorie restriction, and calorie restriction mimetics), targeting inflammaging, senotherapy, parabiosis, stem cell‐based therapies, and epigenetic rejuvenation, have shown promise in slowing aging and extending lifespan in pr …
Bipolar Disorders
ABSTRACT Objectives To identify preliminary insights into the perceived utility and risks of commercially available AI chatbots such as ChatGPT used by individuals with severe mental illness (SMI), namely bipolar disorder, for self‐reflection and mental health support. Methods Data were collected via semi‐structured interviews from two individuals diagnosed with bipolar disorder who independently used ChatGPT for self‐reflection and to explore diagnosis, symptom management, and treatment. Both individuals presented …
JMIR Formative Research
Background Behavioral and psychological symptoms of dementia (BPSD) are among the most challenging aspects of dementia care and contribute substantially to care partner burden. Family care partners, who provide most community-based dementia care, often lack access to evidence-based, nonpharmacological interventions for managing BPSD, particularly in underserved communities. Mobile health (mHealth) apps offer a promising avenue to expand care partners’ access to caregiving support. However, existing dementia caregiv …
Natural and Life Sciences Communications
This study aims to assess motorcycle riding-related functional abilities among older adults and identify high-risk road locations in rural communities of Ubon Ratchathani Province, Thailand, to prevent accidents involving older motorcycle riders. The study administered a driving competency test to 202 older adults, modeled after the Thai driving license test, and required participants to complete a questionnaire. Fifty network partners participated in a focus group to identify potential risks and develop solutions. …
Alzheimer Disease & Associated Disorders
This study examined factors associated with not seeking counseling among 46,156 Korean adults who experienced cognitive impairment in the past year, using data from the 2024 Korea Community Health Survey. Only 8.1% sought counseling. Age-stratified logistic regression showed that counseling-seeking increased with greater disruption of daily activities. Alcohol consumption consistently predicted not seeking counseling across all age groups, while depression was associated with greater counseling seeking. Lower econo …
Journal of Applied Gerontology
Background Namaste Care is a person-centered, non-pharmacological approach supporting comfort and engagement in institutional dementia care. Objective To synthesize quantitative evidence on clinical outcomes associated with Namaste Care among people with dementia living in institutional settings. Methods A systematic search was conducted across eight databases during February 2026. Quantitative studies evaluating Namaste Care or explicit adaptations were included. Methodological quality was assessed using the revis …
Nordic Pulp & Paper Research Journal
Abstract Red mineral pigments are widely used in traditional calligraphy and painting, but the metal ions they contain will catalyze the degradation of cellulose and accelerate the aging of paper. In this study, the effects of four different strengths of gelatin (G50, G100, G200 and G250) on the aging properties of paper were systematically studied using unsized Xuan paper as the base material with ochre as the pigment, and the optimal strength gelatin was selected in combination with three inhibitors EDTA, sodium …
PLOS One
The COVID-19 pandemic negatively impacted mental health, particularly among middle-aged and older adults, who have emerged as especially vulnerable. This scoping review synthesizes findings from 44 population-based studies retrieved from six databases, aiming to map changes in mental health outcomes during the pandemic and identify associated factors. During the global spread and response phase of the pandemic (May 2020–December 2021), a notable rise in depressive symptoms, anxiety symptoms, stress, distress, lonel …
The British Journal of Social Work
Abstract Unpaid carers are essential to the care of people living with cognitive impairment in the UK, yet their lived experiences and identities are often marginalized within policy and practice frameworks. This article presents findings from a qualitative study of unpaid carers in North Wales, exploring how individuals articulate, negotiate, and sometimes resist the identity of ‘carer’. Using a narrative (life story) methodology, the research uncovers the complexity and fluidity of carer identity, shaped by perso …
Clinical Rehabilitation
Objective To evaluate the effects of knee compression using elastic bandages on pain intensity and physical function in individuals with knee osteoarthritis in the short term. Design Three-arm, randomised controlled trial. Setting Individuals with knee osteoarthritis received compression, sham compression, or no bandaging. Main measures Ninety participants were assessed at baseline (Day 1), Day 6 after intervention, and 12 and 24 weeks post-intervention. The primary outcomes were pain intensity assessed using the V …
Journal of Clinical Immunology & Microbiology
Periodontitis has long been described as a chronic inflammatory disease driven by the interaction between a dysbiotic biofilm and an altered host immune response. This model, however, does not fully explain the greater susceptibility, faster progression and poorer treatment response observed in older adults. From a geroscience perspective, biological aging itself reshapes the periodontal environment through inflammaging and immunosenescence, contributing to loss of periodontal homeostasis beyond microbial dysbiosis …
Artefactum - revista de estudos interdisciplinares
Aging causes muscular and neuromotor changes that reduce postural stability and may increase fall risk, particularly when associated with sarcopenia. This study aimed to analyze the limits and convergences among functional assessment methods of postural control in older adults with sarcopenia, considering their ability to identify functional deficits and fall risk. A qualitative and descriptive literature review was conducted using Google Scholar, Scopus, PubMed, and SciELO, with search terms related to aging, musc …
Frontiers in Sports and Active Living
Background This study investigated phase-specific performance, movement smoothness, and turning kinematics during the Timed Up and Go (TUG) test in older adults with and without chronic neck pain (CNP). Methods Eighty-five older adults [CNP, n = 25; control (CON), n = 60] completed an instrumented TUG (iTUG) using wearable inertial sensors. Total TUG duration, spatiotemporal gait parameters (gait velocity, stride length, and cadence), and phase durations (sit-to-stand, walking forward, turning, walking back, and tu …
Odontology
Abstract The microtensile bond strength (µTBS) and failure patterns of a self-curing bulk-fill restorative system (STELA, SDI) were investigated and compared with those of a light-cured bulk-fill and a conventional light-cured restorative system following short- and long-term aging in artificial saliva. Forty-eight human teeth were randomly assigned to three groups ( n = 16): G1, self-curing bulk-fill restorative system; G2, light-cured bulk-fill restorative system; and G3, conventional light-cured restorative syst …
Aging Clinical and Experimental Research
Abstract Background Physical activity (PA) is a pivotal modifiable determinant of intrinsic capacity (IC), a core component of healthy aging. Aims This study aimed to examine the association between PA and the risk of IC impairment among middle-aged and older adults using nationally representative cohorts from China and the United States. Methods Data from CHARLS (2011–2015) and HRS (2010–2018) were used, including 781 and 2,601 participants, respectively. PA was quantified by metabolic equivalents (MET), and IC im …
JAMA Oncology
Importance The treatment of older adults with chemotherapy for early-stage breast cancer involves a complex decision-making process that weighs the competing risks of disease recurrence against the potential harms of treatment. While older adults continue to be underrepresented in therapeutic clinical trials, there is a growing body of evidence to support optimal management of each subtype of early-stage breast cancer, including novel strategies like adjuvant cyclin-dependent kinase 4/6 inhibitors in hormone recept …
The International Journal of Aging and Human Development
Research teams addressing inequalities in aging benefit from diverse perspectives that can strengthen the scientific rigor of the research. We developed a mentored research program to encourage diversity in population health aging research. Our program, Advancing Health Equity and Diversity (AHEaD), focused on reducing barriers to application and enrollment. We received robust interest in the program, including nearly 4,500 applications over 5 years (2021–2025), and welcomed 45 participants. Participants positively …
Business Information Review
Smart library research is expanding quickly, but evidence remains fragmented across technologies, metrics, and evaluation methods. Many studies focus on individual tools, such as RFID shelves or occupancy sensors, while governance, user capacity, and contextual constraints receive limited attention. This fragmentation restricts cross-site learning and slows the development of coherent smart library strategies. Addressing this means the study reviews literature using Google Scholar as the sole database. Iterative ke …
