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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Physical Rehabilitation and Recreational Health Technologies

Effects of Yoga-Based Intervention with Bhramari Pranayama and Chakra Meditation on Sympatho-Vagal Balance in Perimenopausal Women: A Randomized Controlled Trial

Jayachitra Subramanian, Subbulakshmi Velusamy, Ethiraj Balaji, Nirmal Michael Salvi, Erianti

Purpose. Perimenopause is associated with progressive altered autonomic regulation manifesting as sympathetic hyperactivation and impaired parasympathetic modulation, increasing cardiovascular and psychological vulnerability. Heart rate variability (HRV) provides a validated, non-invasive index of cardiac autonomic regulation. Yoga-based interventions incorporating controlled breathing and meditation may favorably modulate sympatho-vagal balance, yet robust randomized controlled trial (RCT) evidence in perimenopaus …

30.08.2026journal-article

Pharmaceutics

Recent Advances in Non-Viral Vectors for Gene Therapy and Gene Delivery: From Lipid Nanoparticles to Engineered Extracellular Vesicles

Yongfeng Yang, Tingting Song, Kaili Huang, Hong Huang, Maoyuan Zhao, Yi Li

Gene therapy and genome editing increasingly depend on the safe, effective, and cell-selective delivery of nucleic acids and protein–nucleic acid complexes. Although viral vectors remain important for applications requiring durable gene expression, non-viral vectors offer advantages in cargo capacity, modularity, transient expression, potential repeat dosing, and avoidance of vector–genome integration. Lipid nanoparticles (LNPs), polymeric nanoparticles, inorganic nanomaterials, extracellular vesicles (EVs), and bi …

30.08.2026journal-article

Journal of Clinical Medicine

Is Morning Exposure Therapy More Successful? Pilot Data on Exposure Process Indicators and Diurnal Cortisol in Obsessive–Compulsive Disorder or Agoraphobia

Michael Kellner, Maja Santai Mareljic, Alexander Yassouridis

Background/Objectives: Glucocorticoids have been shown to improve fear extinction learning in preclinical and human studies. We hypothesized an impact of the circadian rhythm of cortisol on exposure therapy in patients with anxiety spectrum disorders. Methods: Sixteen patients suffering from obsessive–compulsive disorder and eight with agoraphobia participated in a pilot randomized prospective cohort study. During two therapist-guided sessions of exposure therapy with response prevention, both starting either at 08 …

30.08.2026journal-article

Jurnal Ners

Environmental Health Management and Occupational Health and Safety Practices for Green Hospital Implementation: A Mixed-Methods Study in an Indonesian Public Hospital

Hizriansyah Hizriansyah, Muhammad Nawawi, Hendra Setiawan, Bima Brini Wahyu Setiadi, Arif Andriyanto

Green Hospital implementation has become an essential strategy for improving healthcare sustainability by strengthening environmental health management and occupational safety practices. However, empirical evidence regarding EHM and OHS practices supporting Green Hospital implementation in Indonesian public hospitals remains limited. This study aimed to examine EHM and OHS practices supporting Green Hospital implementation at Tripat Gerung Regional Hospital, West Nusa Tenggara, Indonesia. A convergent parallel mixe …

30.08.2026journal-article

European Heart Journal

Safety of withdrawal of pharmacological treatment after recovery from HER2 therapy-related cardiac dysfunction: the HER-SAFE trial

B Dowsing, H-M Dehbi, M S Andres, R Chung, A Oashou, J M Wilson, I Hussein, B Meredith, I Pierce, S Ahmed, J Pedra, O Worn, M Howe, S Assadullah, P Schmid, R Roylance, T Crake, M Westwood, A K Ghosh, D Auger, C M Plymen, J Baksi, M S Nazir, J C Moon, D Chen, A R Lyon, J M Walker, C H Manisty

Abstract Background Heart failure therapy (HFT) is routinely continued in breast cancer survivors after recovery from anti-HER2 cancer therapy-related cardiac dysfunction (CTRCD), despite limited evidence. HER-SAFE is the first randomised trial to assess HFT withdrawal in this population. Methods In this open-label, multicentre, randomised controlled trial, breast cancer survivors with recovered anti-HER2 CTRCD (asymptomatic, left ventricular ejection fraction [LVEF] ≥50%, normalised biomarkers) were randomised to …

30.08.2026journal-article

MedComm

Artificial Intelligence Integration With Nanotechnology for Cancer Therapy

Shengbin Liu, Zhi Liu, Haixing Shi, Chengyi Wei, Ruijie Zhang, Xiangrong Song

ABSTRACT Cancer nanomedicine offers a versatile platform for improving therapeutic index, but its clinical translation remains limited by unpredictable in vivo behavior, heterogeneous biological contexts, and inefficient design paradigms. Artificial intelligence (AI) is emerging as an integrative framework that links data‐driven modeling with nanomedicine design, biological transport, and clinical decision‐making. In this review, we discuss AI‐guided strategies for material design, targeting, payload optimization, …

30.08.2026journal-article

Second Language Research

Is self-reported attentional control associated with second language speech perception?

Georgios P. Georgiou, Wenjun Zhang

Although attention control has been proposed as a potentially relevant source of individual variation in speech perception, its association with nonnative segmental discrimination remains underexplored. The present study investigates whether individual differences in self-reported trait attentional control are associated with the perception of a difficult nonnative consonantal contrast by examining how adult Mandarin Chinese listeners discriminate the Cypriot Greek / m b/–/p/ contrast. Forty native speakers of Mand …

30.08.2026journal-article

International Journal of Counseling and Psychotherapy

The Effect of Schema Therapy on Aggressive Behaviour among Senior Secondary School Students in Oyo State, Nigeria

Augustina Ekeh, Titilayo Monsurat Musa, Adejare adelodun Adejumobi, Adeleye Adewale Olugbemiga

Background: Pervasive aggressive behavior in secondary schools severely undermines school safety, yet conventional school guidance rarely addresses the underlying early maladaptive schemas. Objective: This study aims to investigate the effect of Schema Therapy on aggressive behavior among senior secondary school students in Oyo State, Nigeria. Methods: A quasi-experimental pretest-posttest control group design was employed, involving 116 Senior Secondary School II students with high aggression scores recruited via …

30.08.2026journal-article

Journal of Cardiovascular Electrophysiology

“Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials”

Ali Alsajad Hussein Al‐Janabi, Ali Saad Al‐Shammari, Ahmed W. Hageen, Abdullah Zeyad Hameed Al‐Tuaama, Abdullah Muataz Taha Al‐Ibraheem, Muhammad Shahzaib, Diya Rathi, Khadeeja Ali Hamzah, Mohammedsadeq A. shweliya, Yousif Hameed Kurmasha, Mohamed Wagdy, Marwan M. Refaat

ABSTRACT We aim to compare the impact of left atrial appendage closure vs. medical therapy on clinical outcomes in patients with atrial fibrillation, focusing on key clinical outcomes relevant to thromboembolic prevention. We conducted a PRISMA‐guided systematic review and meta‐analysis of studies comparing LAAC with medical therapy in AF adults. PubMed, Embase, Scopus, ClinicalTrial. gov, and Cochrane Library were searched from inception to March 2026. Outcomes included all‐cause mortality, any stroke, ischemic st …

30.08.2026journal-article

NEW SOLUTIONS: A Journal of Environmental and Occupational Health Policy

Firefighter Turnout Gear and Peri-Governmental Influences

Kira Mok, Gabriel Wasserman, Phil Brown, Alissa Cordner

How do non-governmental standards matter for occupational and environmental health and safety? Internationally recognized standards specify requirements for structural firefighter personal protective equipment (PPE), but concerns have emerged about hazardous chemicals and firefighters’ potential exposures. In this paper, we draw on the case of the National Fire Protection Association's standards for firefighter PPE to develop the concept of peri-governance , work done by non-governmental actors or organizations tha …

30.08.2026journal-article

Scientific Reports

Histological evaluation of pulpal healing following direct pulp capping with polytetrafluoroethylene or melatonin, with or without adjunctive low-level laser therapy in Wistar rat molars

Samah Ahmed Abdelaziz, Latifa Mohamed Abdelgawad, Iman A. Fathy, Sayed eltayab, Ali Mohamed Saafan

Abstract This study evaluated pulpal healing following direct pulp capping with polytetrafluoroethylene (PTFE) or melatonin (MEL), with or without adjunctive low-level laser therapy (LLLT), in Wistar rat molars. Fifty-two maxillary first molars from 26 male Wistar rats were included. Forty-eight molars with standardized pulp exposures were randomly allocated to four groups ( n = 12): Group I, PTFE; Group II, MEL; Group III, PTFE + LLLT; and Group IV, MEL + LLLT; four unexposed molars served as negative controls. LL …

30.08.2026journal-article

Health Expectations

Enhancing the Prospective Acceptability of a Paediatric Speech and Language Therapy Intervention With Parents From Under‐Represented Communities

Lucy Rodgers, Nicola Botting, Ros Herman

ABSTRACT Background Integrating the perspectives of people with lived experience is integral to developing new healthcare interventions. However, individuals from under‐represented communities may face additional barriers to taking part in such patient and public involvement (PPI) activities. Within paediatric speech and language therapy (SLT), under‐represented communities might include families from lower SES backgrounds and/or families where the majority language for that country is not spoken. Excluding familie …

30.08.2026journal-article

Arthroscopy, Sports Medicine, and Rehabilitation

Ten‐Year Post‐traumatic Osteoarthritis Incidence Is Low After Pediatric Isolated Meniscal Surgery but Lower After Meniscal Repair Than Meniscectomy

Annika N. Hiredesai, Alejandro M. Holle, Jay R. Patel, Katelyn T. Koschmeder, Sailesh V. Tummala, Jeffrey M. Vaughn, Karan A. Patel

Purpose To examine the 5‐ and 10‐year incidence of post‐traumatic osteoarthritis (PTOA) after isolated, primary meniscal surgery differentiating between meniscal repair and meniscectomy, in pediatric patients. Methods Pediatric patients (≤16 years) undergoing primary meniscectomy or meniscal repair (2010‐2023) with ≥5‐year follow‐up were identified in the PearlDiver database. Exclusion criteria included prior or concomitant knee injuries, surgeries, or syndromes. Delayed surgery was defined as ≥90 days after diagno …

30.08.2026journal-article

International Journal of Eating Disorders

Autistic Traits in Patients With Anorexia Nervosa Treated With Intensive Enhanced Cognitive Behavior Therapy ( CBT ‐E): A Prospective Cohort Study

Simona Calugi, Anna Dalle Grave, Mirko Chimini, Gianmatteo Cattaneo, Maddalena Conti, Riccardo Dalle Grave

ABSTRACT Objective This study examined the role of autistic traits in patients with anorexia nervosa receiving an intensive, focused form of enhanced cognitive behavior therapy (CBT‐E). The aim was to assess changes in these traits during treatment and their predictive value for outcomes. Method In this prospective cohort study, 81 patients aged 16–65 years were admitted for intensive CBT‐E. Body mass index (BMI), eating disorder psychopathology, general psychopathology, and functional impairment were assessed at b …

30.08.2026journal-article

Jurnal Ilmiah Kesehatan (JIKA)

Cognitive Behavioral Play Therapy to Improve Emotional Regulation in Children With ADHD: A Quasi-Experimental Study

Ayu Pratiwi, Ahmad Abdul Lutfbis, Ahmad Farid Ramadhan, Maratun Nazila

Attention-deficit/hyperactivity disorder (ADHD) affects children’s academic, social, and emotional functioning, highlighting the need for feasible school-based interventions. This study evaluated the effectiveness of Cognitive Behavioral Play Therapy (CBPT) in improving emotion regulation among elementary school children with ADHD. A quasi-experimental pretest-posttest control-group design was used. Sixteen children aged 6–9 years were recruited through total sampling and allocated to an intervention group (n = 8) …

30.08.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Efficacy of Pilates on chronic low back pain in women: A systematic review and meta-analysis

Jiaxing Zhang, Ya Su

Background Chronic low back pain (CLBP) is the most frequent musculoskeletal disorder with many influencing factors, impairing the individual's pain and function management. Objective We conducted this study to explore the effect of Pilates exercise on pain and function in women with CLBP, especially in postmenopausal women. Methods PubMed, Embase, Web of Science, Cochrane Library, PEDro and CINAHL were searched up to April 11, 2026. Randomized controlled trials on the effect of Pilates exercise on women with CLBP …

30.08.2026journal-article

Journal of Artificial Intelligence and Information

Analysis of Occupational Mental Health Status and Influencing Factors among Tertiary Industry Workers

Yuqin Wen, Yu Luo, Jie Xu

Objective: This study investigates and statistically analyzes the mental health issues of workers in the tertiary industry, examining the influencing factors to provide empirical evidence for the development of strategies aimed at promoting occupational mental health. Methods: A cross-sectional study was conducted. A total of 2,705 front-line workers from five industries—environmental sanitation, transportation, education, delivery/takeout and healthcare—were selected using cluster sampling. Participants’ physical …

30.08.2026journal-article

International Journal of Stroke

Clinical Outcomes among Patients with Active Cancer and Acute Ischemic Stroke Treated with Antiplatelet versus Anticoagulant Therapy.

Gianluca Costamagna, Andreas Hottinger, Francoise Livio, Babak Benjamin Navi, Davide Strambo, Patrik Michel

Background: Patients with acute ischemic stroke (AIS) and active cancer (AC) face high risks of recurrent stroke and death. Evidence guiding antithrombotic selection remains limited. Aims: To investigate post-AIS prescribing patterns of antiplatelet versus anticoagulant therapy in AIS patients with AC and their associated clinical characteristics and outcomes. Methods: We retrospectively analyzed 2003–2024 data from the Acute-Stroke-Registry-and-Analysis-of-Lausanne (ASTRAL). We included patients with AC discharged …

30.08.2026journal-article

Tropical Journal of Pharmaceutical and Life Sciences

Traditional Knowledge and Molecular Evidence of Medicinal Plants for Multi-Target Dengue Therapy: A Review

Mohammed Anas, Farhat Jahan

Dengue fever continues to intensify as a major global public health challenge, driven by climate change, rapid urbanization, and expanding vector habitats, while the absence of a universally safe and effective antiviral therapy remains a critical limitation. Unlike conventional single-target antivirals, plant-based interventions offer a multi-target therapeutic strategy capable of simultaneously inhibiting viral replication, modulating immune dysregulation, reducing oxidative stress, stabilizing endothelial functio …

30.08.2026journal-article

Psychoactives

Psilocybin-Assisted Therapy for Alcohol Use Disorder: A Systematic Review of Clinical Evidence

Laura Schäffert, Human-Friedrich Unterrainer

Background: Alcohol use disorder (AUD) remains a leading contributor to global morbidity, yet conventional treatments often yield suboptimal outcomes and high relapse rates. Psilocybin-assisted therapy has re-emerged as a potential intervention for substance use disorders, but its effectiveness and safety in AUD specifically remain to be comprehensively evaluated. Objective: To review and synthesize available evidence on the efficacy and safety of psilocybin-assisted therapy in adults with AUD. Methods: A systemati …

30.08.2026journal-article

Acta Politica

Long-term occupational upgrading and party support in German districts

Gina-Julia Westenberger

Abstract While the structural transformation of Western economies has deepened spatial inequality and polarised voting behaviour, we lack a nuanced understanding of how the resulting regional occupational change maps onto electoral outcomes. Focusing on Germany, this article examines how three decades of occupational upgrading relate to party vote choice in the 2017 and 2021 federal elections. Combining administrative employment data with fine-grained district-level voting results and geo-coded individual survey da …

30.08.2026journal-article

Frontiers on Healthcare Research

A Little of Everything, Just In Time: Multimodal Opioid-Sparing Anesthesia for a Twin Pregnancy in Decompensated Heart Failure Caused by Severe Mitral Stenosis

Department of Anesthesiology and Intensive Therapy, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Muhammad Imam Mulia Muhammad Imam, Department of Anesthesiology and Intensive Therapy, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Arief Cahyadi Arief

Background: Rheumatic heart disease remains a leading cause of valvular heart disease among women of reproductive age in low- and middle-income countries. Severe mitral stenosis complicating pregnancy substantially increases the risk of acute cardiac decompensation because of the hemodynamic load imposed by gestation, and anesthetic management becomes considerably more complex when it is combined with atrial fibrillation with a rapid ventricular response and a multifetal pregnancy. Reports describing general anesth …

30.08.2026journal-article

Medical Physics

Machine Model‐Specific Delivery Sequence Optimization for Spot‐scanning Proton Arc Therapy Using a Compact Superconducting Synchrocyclotron

Peilin Liu, Lewei Zhao, Xiaoda Cong, Gang Liu, Xiaoqiang Li, Xuanfeng Ding

Abstract Background Spot scanning proton arc therapy (SPArc) combines the dosimetric advantages of proton therapy with the beam‐angle freedom of arc delivery. However, current planning algorithms rely on static delivery assumptions that do not account for the temporal characteristics of pulsed‐beam synchrocyclotron systems during continuous gantry rotation. This mismatch between nominal plans and actual treatment delivery may lead to clinically meaningful dose deviations. Purpose To develop and evaluate a dynamic a …

30.08.2026journal-article

VIEW

Biopolymer‐Based Polyelectrolyte Nanoplatforms for Targeted Photodynamic Therapy of Breast Cancer

Athira Narayanan, Benedetta di Chiara Stanca, Daniela Pinheiro, Laura Giannotti, Fabrizio Damiano, André Ferreira Moreira, Sónia Miguel, Leonardo Lamanna, Eleonora Stanca, Maria Grazia Raucci, Gianpiero Colangelo, Luisa Siculella, Alessandro Sannino, Paula Coutinho, Christian Demitri

Abstract Nanomedicine has reshaped healthcare, especially in targeted drug delivery systems (DDSs) and diagnostics, addressing the limitations of traditional cancer therapies. Integration of photodynamic therapy (PDT) with nanoparticle‐based DDSs has significantly improved the targeted accumulation and pharmacokinetic properties of photosensitizers within tumor cells, enabling selective tumor cell death while sparing healthy tissues. This study developed chitosan‐sericin polyelectrolyte nanoparticles (CSSN NPs) via …