EUVIMEDEuropean Health Evidence
Uhr 10/10Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Medizin · Seite 37

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

European Journal of Trauma and Emergency Surgery

ABCB5⁺ mesenchymal stem cells enable high-ratio cellular augmentation of bone grafts without loss of osteogenic function

Jakob Hofmann, Tim Niklas Bewersdorf, Ulrike Sommer, Kai Borcherding, Karsten Thiel, Christoph Ganss, Matthias Gerstner, Markus H. Frank, Gerhard Schmidmaier, Mark Andreas Kluth, Tobias Grossner

Abstract Autologous bone grafting remains the standard for reconstruction of bone defects but is constrained by limited graft volume and loss of osteogenic capacity when expanded with acellular materials. We hypothesized that allogeneic ABCB5⁺ mesenchymal stem cells (MSCs) can serve as a biologic cell source to augment bone marrow-derived MSC (BM-MSC) populations without impairing osteogenesis. Primary human BM-MSCs from five donors were combined with GMP-manufactured ABCB5⁺ MSCs at graded replacement ratios (0–95% …

03.09.2026journal-article

Clinical Kidney Journal

Rituximab therapy achieves comparable remission to cyclophosphamide in ANCA-associated vasculitis with severe KIDNEY involvement

Nishant Chaudhari, Azm Ul Hussain, Lee Quill, Joshua Harridine, Kashif Eqbal, Lorraine Harper, Dimitrios Chanouzas

Abstract Introduction The RAVE/RITUXIVAS trials established rituximab (RTX) therapy in ANCA-associated vasculitis (AAV). However, RAVE excluded patients with severe renal involvement (creatinine > 354 µmol/L). Whilst RITUXIVAS did not, treatment included RTX with 2 cyclophosphamide (CYC) pulses. This study reports outcomes in AAV patients with severe renal involvement treated with RTX alone compared to CYC, together with high dose steroids. Methods Data were collected retrospectively for all consecutive AAV present …

03.09.2026journal-article

Frontiers in Medicine

Case Report: A cluster of cases with rash associated with Chlamydia pneumoniae infection

Tianyi Wu, Gang Wang, Nannan Xu, Ke Xu, Gonghai Chen

We report a case of clustered rashes among teenagers associated by Chlamydia pneumoniae (CP) infection. Most patients only presented with rashes without significant fever or other respiratory tract symptoms. Metagenomic next-generation sequencing (mNGS) of blood samples identified the culprit - the nucleic acid sequence of CP was detected in the peripheral blood of the index case. The results of targeted next-generation sequencing (t-NGS) of throat swabs further supported the presence of CP. After antibiotic treatm …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Combined assessment of carotid intima–media thickness and epicardial fat thickness for cardiovascular risk stratification in asymptomatic South Indian adults

Ramesh Sankaran, Dolly Agarwal, Rahul Mittal, Shankar Srinivasan, Nagendra Boopathy Senguttuvan, Alex Karev, Sadhanandham Shanmugasundaram, Balasubramaniyan Jayanthi Venkata, Vinod Kumar Balakrishnan, Preetam Krishnamurthy, Sadagopan Thanikachalam, Murthy Jayanthi Satyanarayana

Background Carotid intima-media thickness (cIMT) and epicardial fat thickness (EFT) are non-invasive imaging markers associated with cardiovascular risk. This study evaluated the associations between cIMT, EFT, individual cardiovascular risk factors, cumulative cardiovascular risk-factor burden in asymptomatic adults undergoing routine cardiovascular health assessment. Methods A cross-sectional study was conducted in 925 asymptomatic adults aged ≥18 years undergoing routine cardiovascular health evaluations. Partic …

03.09.2026journal-article

Frontiers in Neurology

Interpretable machine learning–based prediction of 90-day mortality after endovascular treatment in acute large vessel occlusion stroke

Yuanfang Zhou, Xiaoxia Li, Guokuan Feng, Chuanhang Lin, Bao Liao

Background Despite high recanalization rates after endovascular treatment (EVT) for acute ischemic stroke due to large vessel occlusion (AIS-LVO), 15%−20% of patients still die within 90 days. Existing prognostic models predominantly target functional disability rather than mortality, and rarely incorporate calibration, clinical utility, or interpretability. We aimed to develop and internally validate interpretable machine learning (ML) models for dynamic post-EVT in-hospital prediction of 90-day all-cause mortalit …

03.09.2026journal-article

Frontiers in Medicine

Case Report: Electrode perforation with normal pacemaker parameters leading to hemorrhagic shock: a rare case report of the “penetration-exit-re-entry” phenomenon

Zuoan Qin, Jian Yang, Li Luo, Shi Chen, Fei Yang

Background Permanent pacemaker implantation via subclavian vein puncture may induce rare but life-threatening iatrogenic vascular injury. Vascular perforation with pacing lead penetration-exit-re-entry trajectory accompanied by normal intraoperative pacing parameters is reported extremely rarely, which greatly increases the risk of missed diagnosis. Case presentation A 70-year-old female patient with complete atrioventricular block received dual-chamber pacemaker implantation. All intraoperative lead electrical ind …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Perfluorooctanoic acid–associated complement factor B upregulation and atrial fibrillation–related molecular alterations: integrated network toxicology, Mendelian randomization, molecular dynamics, and HL-1 cell analyses

Dan Li, Chuanfeng Bai, Jinping Zhao

Background Perfluorooctanoic acid (PFOA) is a persistent environmental pollutant associated with cardiovascular dysfunction, but the molecular links between PFOA exposure and atrial fibrillation (AF) remain unclear. We aimed to prioritize a candidate mediator connecting PFOA with AF and examine its associated molecular effects in atrial cardiomyocytes. Methods PFOA-associated or computationally predicted genes from CTD, STITCH, and SwissTargetPrediction were integrated with AF-associated genes. Complement factor B …

03.09.2026journal-article

Journal of Imaging Informatics in Medicine

Artificial Intelligence for Cerebral Aneurysm Management: Integrating Imaging, Hemodynamics, and Clinical Decision Support

Reza Bozorgpour, Pilhwan Kim, Jacob Rammer

Abstract Cerebral aneurysms are complex vascular lesions whose rupture can result in subarachnoid hemorrhage (SAH), a condition associated with substantial morbidity and mortality. Although current clinical risk assessment relies primarily on morphological characteristics such as aneurysm size and location, these factors alone are often insufficient for individualized rupture risk prediction. Advances in artificial intelligence (AI) and machine learning (ML) have enabled the integration of imaging, clinical, morpho …

03.09.2026journal-article

South Asian Journal of Cancer

A retrospective analysis of treatment patterns and outcomes in carcinoma of the external auditory canal

Bal Krishna Mishra, Akhil Kapoor, Anuj Gupta, Bipinesh Sansar, Ayushi Pragya, Aseem Mishra, Ashutosh Mukherji, Sambit S Nanda, Ankita Rungta Kapoor, Ajay Kumar Choubey, Arvind Suresh, Satyendra Narayan Singh, Shreya Shukla

Objectives: Carcinoma of the external auditory canal (EAC) is a rare form of head and neck cancer, which accounts for

03.09.2026journal-article

RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218

INTELIGÊNCIA ARTIFICIAL EM HEMATOLOGIA LABORATORIAL: IMPACTO NO DIAGNÓSTICO

Éverton José Ferreira de Araújo, Janyerson Dannys Pereira da Silva, Danielle Yasmin Moura Lopes de Araujo, José Couras da Silva Filho, Marcelo Rodrigues Mendes, Pedro Simão da Silva Azevedo, Maria Luíza Passos Ribeiro Maia, Isadora Marques Silva Sousa, Mariana Isabela Beserra de Menezes

A inteligência artificial (IA) tem promovido avanços significativos na hematologia laboratorial ao ampliar a capacidade de processamento e interpretação de dados clínicos, morfológicos, imunofenotípicos e moleculares. O presente estudo teve como objetivo revisar a literatura científica acerca das aplicações da IA na hematologia laboratorial, destacando seu impacto no diagnóstico, suas principais contribuições, limitações e perspectivas futuras. Realizou-se uma revisão integrativa da literatura por meio de busca est …

03.09.2026journal-article

Journal of Travel Medicine

Orthopaedic Injuries among International Travellers in Nepal

Abhishek Shrestha, Ishwor Ghimire Padhya, Jasmine Shrestha, Pratigya Aryal, Prativa Pandey

Highlight/Teaser International travellers in Pokhara experience a considerable burden of orthopaedic injuries. This study describes their injury patterns, management, and outcomes, providing evidence to strengthen preventive advice, trauma preparedness, and clinical services in popular adventure-travel destinations.

03.09.2026journal-article

ACS Applied Materials & Interfaces

Non-Annealing Treatment Mechanism of Electron Transport Layers for High-Performance Inverted Perovskite Solar Cells

Jiangping Xing, Weixuan Liu, Haifan Zhou, Qinghua Cao, Deping Xiong, Aliaksandr Smirnov, Xiaoli Zhang, Hui Liu

Abstract Inverted perovskite solar cells (IPSCs) have presented great potential in the photovoltaic field due to their outstanding optoelectronic properties. However, the widely used electron transport layer of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) in IPSCs presents some issues such as poor passivation effect, insufficient film coverage, and suboptimal energy-level alignment, and the influence of annealing treatment of PCBM on device performance has rarely been investigated. Therefore, in this work, we …

03.09.2026journal-article

Developmental Medicine & Child Neurology

Risk factor profiles in infants born preterm and at term with cerebral palsy in Argentina: Findings from the Argentine Cerebral Palsy Register

M. Mercedes Ruiz Brunner, Carla Gil, María Elisabeth Cieri, Ana Laura Condinanzi, L. Johana Escobar Zuluaga, Federico Sanchez, Gulam Khandaker, Israt Jahan, Nadia Badawi, Eduardo Cuestas

Aim To describe the patterns of co‐occurrence between previously documented risk factors and gestational age in infants with cerebral palsy (CP) registered in the Argentine Cerebral Palsy Register (Registro Argentino De Parálisis Cerebral [RAR‐PC]). Method This register‐based, cross‐sectional study analysed data from individuals with confirmed CP registered in the RAR‐PC. Family interviews and medical record reviews were conducted. The variables analysed included CP characteristics, a predefined set of prenatal, pe …

03.09.2026journal-article

Journal of Hand Surgery (European Volume)

Targeted tenosynovial biopsy during carpal tunnel release for detection of transthyretin amyloid deposits

Nicolas Bigorre, Alexandre Petit, Jérome Brunet, Fabrice Rabarin, Julien Jeanneteau

Introduction: Carpal tunnel syndrome is increasingly recognized as an early musculoskeletal manifestation of transthyretin amyloidosis. Tenosynovial biopsy during carpal tunnel release may detect transthyretin amyloid deposits, but the yield of a targeted strategy remains uncertain. Methods: We conducted a single-centre comparative before-after study of 347 patients undergoing carpal tunnel release with tenosynovial biopsy. The non-targeted cohort was recruited between October 2021 and July 2023 and the targeted co …

03.09.2026journal-article

Clinical Research in Cardiology

Gaps in lipid management among high-risk patients without prior MI or stroke: the VESALIUS-REAL global study

Queenie Chan, Jaimini Cegla, Ulrich Laufs, Jan H. Cornel, Gaetano M. De Ferrari, Emil Hagström, Huei-Kai Huang, José Lopez-Miranda, Suna Avcil, Corinne Brooks, Thomas Cars, Adrienne Y. L. Chan, Celine S. L. Chui, Michael Duxbury, Edward Chia-Cheng Lai, David Neasham, Andreas Ochs, James O’Kelly, Gabriel Paiva da Silva Lima, Naomi Reimes, Swati Sakhuja, Shih-Chieh Shao, Ju-Young Shin, Mahendra Sibartie, Ilona Verburg, Matthew J. Budoff, Kyung Woo Park, Kenichi Tsujita, Kai Hang Yiu, Nafeesa Dhalwani, Ian C. K. Wong

Abstract Background Real-world evidence on lipid-lowering therapy (LLT) use and low-density lipoprotein cholesterol (LDL-C) control in patients at high cardiovascular (CV) risk without prior myocardial infarction (MI) or stroke remains limited. We evaluated LLT use, treatment intensification, LDL-C monitoring, and LDL-C goal attainment across North America, Europe, and Asia-Pacific. Methods VESALIUS-REAL is a retrospective observational study using a common protocol across 11 databases between 2017 and 2022. Eligib …

03.09.2026journal-article

Clinical Microbiology Reviews

Human vascular pythiosis: pathogenesis, diagnosis, and evidence-informed management

Nitipong Permpalung, Sadeep Medhasi, Pattama Torvorapanit, Rongpong Plongla, Navaporn Worasilchai

SUMMARY Human vascular pythiosis is a rare, life-threatening angioinvasive infection caused predominantly by the oomycete Pythium insidiosum . Unlike ocular or cutaneous pythiosis, the vascular form is defined by arterial wall invasion, long-segment thrombosis, limb ischemia, aneurysmal complications, and high risks of amputation and death. Although P. insidiosum is broadly distributed in freshwater environments, reported human vascular disease remains concentrated in Thailand, indicating that exposure alone is ins …

03.09.2026journal-article

European Journal of Clinical Microbiology & Infectious Diseases

Diagnosis of pneumococcal pneumonia using quantitative PCR targeting lytA and piaB in adult patients with community-acquired pneumonia

Nienke Paternotte, Willem R. Miellet, Tessa Nieuwenhuijsen, Rob Mariman, Wil A. van der Reijden, Wouter Rozemeijer, Elisabeth A.M. Sanders, Dominic Snijders, Cornelis H. van Werkhoven, Marc J.M. Bonten, Krzysztof Trzciński, Wim G. Boersma

Abstract Purpose Accurate diagnosis of pneumococcal pneumonia remains challenging due to suboptimal sensitivity of conventional microbiological methods. Molecular techniques may improve Streptococcus pneumoniae detection, but their clinical utility remains uncertain. Methods In this prospective observational study, we compared conventional diagnostics with qPCR-based detection of lytA and piaB genes in nasopharyngeal, oropharyngeal, saliva, and sputum samples collected from adults with community-acquired pneumonia …

03.09.2026journal-article

Journal of Clinical Medicine

Association Between DLCO and Echocardiographic Right Ventricular–Pulmonary Arterial Coupling in Idiopathic Pulmonary Fibrosis

Francesca Coppi, Susan Darroudi, Giulia Renda, Alessandra Lodeserto, Arianna Maini, Damiano De Cesare, Youssef Othman, Martina Mercati, Dalia Caleffi, Filippo Gozzi, Francesco Marangi, Dario Andrisani, Federica Andolfi, Alessio Baccarani, Daniela Aschieri, Anna Vittoria Mattioli, Francesco Fedele, Enrico Clini, Stefania Cerri, Gianluca Pagnoni

Background: Idiopathic pulmonary fibrosis (IPF) is frequently complicated by pulmonary vascular involvement and right ventricular (RV) dysfunction, both of which adversely affect prognosis. The relationship between impaired gas exchange and echocardiographic indices of RV function, particularly the TAPSE/PAPs (tricuspid annular plane systolic excursion/systolic pulmonary artery pressure) ratio as a marker of RV–pulmonary arterial (RV–PA) coupling, has not been fully characterized. Methods: We retrospectively evalua …

03.09.2026journal-article

Journal of Clinical Medicine

The Association of SARIFA with Poor Prognosis and Aggressive Tumor Phenotypes in Cancers: A Meta-Analysis

Jiaqi Lao, Guangwei Tian, Lin Guan

Background: SARIFA (Stroma Areactive Invasion Front Areas) is an emerging histopathological biomarker defined by direct tumor–adipocyte contact at the invasive front. Preliminary studies suggest its association with poor prognosis, but evidence remains fragmented across cancer types. This meta-analysis aims to systematically evaluate the prognostic value of SARIFA for overall survival (OS) and its correlation with aggressive tumor phenotypes. Methods: Following PRISMA guidelines, we searched PubMed, Embase, Web of …

03.09.2026journal-article

Physics in Medicine & Biology

S2V-DREME: a time-resolved slice-to-volume MR image reconstruction framework with dynamic reconstruction and motion estimation

Xiaoxue Qian, Hua-Chieh Shao, Jie Deng, Yan Dai, You Zhang

Abstract Objective. Existing volumetric magnetic resonance imaging (MRI) techniques are constrained by the trade-off between acquisition time and image quality, limiting accuracy in motion-impacted sites such as the liver. To enable fast, better-quality volumetric imaging with sufficient spatiotemporal resolution, we developed a time-resolved volumetric MRI technique that recovers 3D volumes from acquired 2D MR slices for real-time 3D anatomy and motion tracking. Approach. 2D MR slices dynamically acquired in time …

03.09.2026journal-article

Indian Journal of Radiology and Imaging

Digital Twins in Oncology: From Multimodal Data Integration to Precision Clinical Practice

Annamalai Vairavan, Rupsa Bhattacharjee, Bagyam Raghavan

Oncology digital twins are patient-specific computational models that are built by combining electronic health records, multiomics genomic data, and diagnostic imaging to simulate individual tumor biology and predict multiple treatment-related outcomes. Conceptually originated from aerospace engineering, it has matured clinically through convergent advances in radiomics, mechanistic tumor modeling, pharmacokinetic- pharmacodynamic systems, federated machine learning, and, most recently, large language model (LLM)-b …

03.09.2026journal-article

Cancer

Long‐term outcomes and patterns of failure in patients with thymic malignancies treated with surgery and radiation therapy

Oded Icht, Inbar Nardi‐Agmon, Paaladinesh Thavendiranathan, Shaf Keshavjee, Amiya Agrawal, John‐Michael Miro, Omar Badran, Geoffrey Liu, Xiang Y. Ye, B. C. John Cho, Andrea Bezjak, Andrew Hope

Abstract Background The role of peri‐operative radiation therapy in thymic epithelial tumors remains controversial, and randomized data are lacking. The authors evaluated recurrence patterns, pathologic predictors of recurrence, and long‐term survival among patients who underwent surgery and received peri‐operative radiation at a high‐volume tertiary center. Methods The authors conducted a retrospective cohort study of patients who had thymic malignancies treated surgically between 2004 and 2021. Clinical, patholog …

03.09.2026journal-article

Anesthesia & Analgesia

Remote Ischemic Preconditioning and Survival in Noncardiac Surgery: An Updated Meta-analysis of Randomized Trials

Rosa Labanca, Federico Mattia Oliva, Stefano Fresilli, Maurizio Carravetta, Simone Vietri, Gaetano Lombardi, Marilena Marmiere, Luigi Beretta, Alberto Zangrillo, Domenico Pontillo, Stefano Turi, RIPC Study Group

BACKGROUND: Remote ischemic preconditioning (RIPC) demonstrated potential benefits in terms of organ protection in preclinical and several clinical settings. This systematic review of randomized controlled trials (RCTs) evaluates the association of RIPC with mortality and other relevant clinical outcomes in patients undergoing noncardiac surgery. METHODS: We conducted a systematic review and meta-analysis of RCTs assessing the effects of RIPC in adult patients undergoing noncardiac surgery. A comprehensive search w …