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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Neuro-Cell Molecular Research

Evaluation of Anemia in Geriatric Patients Treated at Bingol State Hospital in 2017

Emine Aydin Bayat, Okan Arihan, Özlem Ergul

Anemia is a worldwide health problem. The aim of the study was to determine how anemia was affected by sociodemographic characteristics and factors such as treatment in hospital, and to evaluate anemia according to morphological, age groups and anemia severity level in individuals with anemia. The study was conducted retrospectively in geriatric patients admitted to Bingöl State Hospital. The incidence of anemia was determined in both inpatients and outpatients, and in men and women. Patients with anemia were class …

31.08.2026journal-article

Clocks & Sleep

HRV-Based Respiratory-Rate Estimation in Older Adults: Error Modeling and Pilot Validation for Wearable Sleep Monitoring

Emi Yuda, Naoya Morikawa, Junichiro Hayano

Respiratory frequency is a critical biomarker in sleep medicine and circadian biology. We investigated whether the high-frequency (HF) component of heart-rate variability (HRV)—which reflects respiratory sinus arrhythmia (RSA)—can serve as a non-invasive proxy for breathing rate estimation from ECG or PPG. We employed a two-stage validation design: (1) a physiologically calibrated simulation study (N = 30 per condition, five conditions, 180 s recordings) for controlled error characterization using the PhysioNet ECG …

31.08.2026journal-article

Revista jurídica. Investigación en ciencias jurídicas y sociales

Acceso a la justicia de personas adultas mayores en Paraguay

Victor Manuel Benítez Salinas, María Eliane Ovelar Dure

Las personas adultas mayores enfrentan barreras sistémicas que condicionan la efectividad de sus derechos fundamentales ante los órganos jurisdiccionales. El trabajo tuvo como objetivo analizar el grado de garantía del derecho de acceso a la justicia de las personas adultas mayores en el contexto paraguayo, a partir del examen del marco normativo interno y su conformidad con los estándares del Sistema Interamericano de Derechos Humanos. La metodología responde a un tipo de investigación dogmático–jurídica, que se d …

31.08.2026journal-article

Aging Cell

Integrative Analysis Uncover the Effects and Multi‐Omics Features of Thigh Muscle Fat Infiltration

Yiwei Zhang, Qin Dang, Xizeng Zong, Haowei Chen, Simin Wen, Siqi Xu, Kunyan Wang, Xiaoshuai Wang, Jianwei Zhu, Zhaohua Zhu, Changhai Ding, Guangfeng Ruan, Yan Zhang

ABSTRACT The health impacts and underlying biological pathways of thigh muscle fat infiltration (TMFI) remain incompletely understood. In this study, we analyzed TMFI measured by magnetic resonance imaging in 55,120 UK Biobank participants and found that higher TMFI was significantly associated with all‐cause mortality as well as with all major system‐specific diseases examined ( p values ranged from 2.50 × 10 −88 to 9.97 × 10 −04 ). TMFI also mediated the effects of lifestyle factors on health‐related outcomes, wi …

31.08.2026journal-article

International Journal of Innovative Technologies in Social Science

A LITERATURE REVIEW OF SGLT2 INHIBITORS IMPACT ON MAJOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER AND PARKINSON DISEASE

Jakub Jucha, Dominik Zając, Dominika Darasz, Artur Łukawski, Lesia Slobozheniuk, Magdalena Bieniak, Marta Kaczorek, Krzysztof Machnik, Oliwia Dziewięcka, Wojciech Ziębka

SGLT2i (sodium-glucose cotransporter 2 inhibitors), also called flozins or gliflozins, are a group of hypoglycemic agents that have revolutionized the approach in treatment of T2DM (type 2 diabetes mellitus). Recent years have witnessed a rise in number of neurological conditions, which requires novel approaches to be examined to provide neuroprotection in these patients. Some studies suggest that presence of SGLT2 receptors in the central nervous system can provide possible neuroprotective properties in Alzheimer …

31.08.2026journal-article

JURNAL ILMU KEFARMASIAN INDONESIA

Comparative analysis of DALY in people with diabetes mellitus between Central Java and Yogyakarta

Akbar Eka Nugraha, Devi Yanthre Manurung

Diabetes mellitus (DM) is a non-communicable disease with an increasing health burden. Differences in disease burden in Indonesia can be attributed to various factors. Therefore, a comparative analysis of disease burden based on DALY is needed to understand the differences in the epidemiological characteristics of DM in Central Java and Yogyakarta. This study is a comparative descriptive study with a quantitative approach using secondary data. DALY and its components were analyzed to observe trends, calculate the C …

31.08.2026journal-article

Technology audit and production reserves

Development of a marketing strategy for realizing the economic potential of people with disabilities under conditions of inclusive economic development

Diana Raiko, Yuliia Shypulina, Hanna Paimash

The object of research is the process of implementing a marketing strategy for the potential of people with disabilities in the system of inclusive marketing for the development of the national economy. A marketing strategy for the realization of the labor potential of people with disabilities has been developed by integrating inclusive marketing mechanisms to ensure sustainable inclusive development using a complex of economic and mathematical models. An assessment of the potential of people with disabilities usin …

31.08.2026journal-article

Acute and Critical Care

Admission characteristics and factors associated with outcomes in elderly patients aged 75 years and older in a level 3 ICU in Nepal: a 4-year registry-based retrospective study

Kishor Khanal, Saroj Poudel, Sunidhi Aryal, Rabin Bhurtel, Anup Ghimire, Ashim Regmi

Background: The global rise in elderly populations has led to increasing admissions of older adults to intensive care units (ICUs). Understanding predictors of mortality in the very elderly is essential, particularly in low- and middle-income countries (LMICs) where ICU resources are limited.Methods: This retrospective observational study analyzed 1,028 ICU patients aged ≥75 years admitted to a level 3 ICU in Nepal. Demographics, comorbidities, frailty score, Acute Physiology and Chronic Health Evaluation II (APACH …

31.08.2026journal-article

npj Dementia

Peripheral blood microarray-based transcriptomic and epigenetic analyses identify immune, inflammation, and metabolic dysregulation in Alzheimer’s disease

Brendan A. Mitchell, Isabella Hausle, Sara Smith, Pamela Thropp, Marina Sirota, Duygu Tosun, for the Alzheimer’s Disease Neuroimaging Initiative

Abstract Leveraging multi-omics to better understand the molecular signatures and pathways underlying Alzheimer’s disease (AD) pathogenesis is critical for early diagnosis and disease modifying interventions. We performed peripheral blood transcriptome ( N = 669) and epigenome microarray analyses ( N = 553) on non-Hispanic white participants from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to identify molecular signatures of AD. We identified specific transcripts (e.g., MAPK14 , GM2A , CD177 ) and co-exp …

31.08.2026journal-article

Frontiers in Neuroscience

The spectrum of C9orf72 repeat lengths in Portuguese frontotemporal dementia and amyotrophic lateral sclerosis patients: from pathogenic expansions to intermediate alleles

Maria Rosário Almeida, Miguel Tábuas-Pereira, Anabela Matos, Ana Santos, Carolina Teixeira, Inês Baldeiras, Marisa Lima, Isabel Santana

Introduction Frontotemporal dementia and amyotrophic lateral sclerosis are clinically distinct disorders that share a common genetic etiology, with pathogenic hexanucleotide repeat expansions in the C9orf72 gene representing the most frequent genetic cause of both conditions. In this study we aim to determine the frequency of C9orf72 repeat expansions in patients with FTD and/or ALS and their at-risk relatives from central Portugal, and to analyze the distribution and repeat size of intermediate alleles within this …

31.08.2026journal-article

Frontiers in Genetics

A workshop considering genetic research and data collection with American Indian and Alaska Native people outside of Tribal jurisdiction

Julie A. Beans, Jessica W. Blanchard, Vanessa Y. Hiratsuka, Taiawagi Helton, Stephanie Russo Carroll, Denise A. Dillard, Raymond Orr, Francine C. Gachupin, Sara C. Hull, Rodney C. Haring, Nanibaa’ A. Garrison, Bobby Saunkeah, Krystal S. Tsosie, Aaron J. Goldenberg, David Wilson, Richard R. Sharp, Joseph Yracheta, Erika Blacksher, R. Brian Woodbury, Dalaki Livingston, Paul Spicer

Introduction In the United States (US), Tribes are sovereign nations and have the right to oversee research conducted with Tribal citizens. However, it is unclear who should approve research protocols when data from American Indian and Alaska Native (AIAN) people are collected off Tribal lands. As genetic research continues to advance and transform the delivery of healthcare, equitable inclusion of AIAN people is necessary, but oversight of research needs clarity. Methods We held a 3-day workshop with US thought le …

31.08.2026journal-article

Journal of Korean Academy of Nursing

Effects of a health literacy program on COVID-19 awareness and preventive behaviors among older adults in Bangkok, Thailand: a quasi-experimental study

Walaya Tupanich, Sasawan Attaworakun, Suteekarn Chaiyalap, Nattanan Wattanawikan

Purpose: This study examined the effectiveness of a health literacy (HL) enhancement program in improving awareness of and preventive behaviors related to coronavirus disease 2019 (COVID-19) among older adults in an urban community in Bangkok, Thailand.Methods: This quasi-experimental study included 76 older adults in Dusit District, Bangkok. Eight participants were lost to follow-up; however, all 76 participants (38 per group) were included in the primary analysis using all available observations. The intervention …

31.08.2026journal-article

BMC Psychology

Stigma concerns and depressive symptoms among people ever infected with COVID-19 in Hong Kong: cross-sectional mediation via perceived stress and maladaptive cognitive emotion regulation

Yanqiu Yu, Mason M.C. Lau, Joseph T.F. Lau

Abstract Background Stigma concerns are common during outbreaks of emerging respiratory infectious diseases and have been associated with mental distress such as depressive symptoms. This study investigated the associations between stigma concerns related to COVID-19 infection and depressive symptoms among people who had ever contracted COVID-19 (PECC), and whether these associations would be significantly mediated by perceived stress and maladaptive cognitive emotion regulation of rumination and catastrophizing. M …

31.08.2026journal-article

Przegląd Socjologii Jakościowej

Od ubrania oczywistego, przez niezrozumiałe, po ubranie nieoczywiste, czyli o tym, jak zmieniał się ubiór osób starszych i jego społeczna percepcja. Casus Polski

Emilia Kramkowska

Wykorzystując w tekście podejście interakcjonizmu symbolicznego, a dokładniej koncepcję Gregory’ego Stone’a, autorka traktuje ubiór jako komunikat, zamierzony lub niezamierzony, za pomocą którego człowiek niewerbalnie komunikuje własną tożsamość i afiliację społeczną. Recenzja ubioru jednostki dokonywana przez różne osoby z otoczenia społecznego nie pozostaje obojętna zarówno dla niej samej (i jej tożsamości), jak i dla tych, którzy recenzji dokonują. Stone wyróżnił trzy sposoby recenzowania autoidentyfikacji jedno …

31.08.2026journal-article

Kurnia Mengabdi: Jurnal Pengabdian kepada Masyarakat

Counseling and Facilitation of Testament Deed Preparation for Older Adults and Low-Income Urban Families to Prevent Inheritance Disputes

Henny Saida Flora, Suryani Intan Pratiwi Puwa, Anstasia Sarjono, Ahmad Yani

This community service article examines a legal counseling and facilitation program on testament deed preparation for older adults and low-income urban families in an urban Indonesian setting. The program was designed in response to the continuing vulnerability of families who possess limited legal literacy, fragmented family communication, and inadequate access to formal legal assistance in inheritance matters. Indonesian civil law recognizes inheritance by testament, while the Civil Code also preserves mandatory …

31.08.2026journal-article

International Journal for Research in Applied Science and Engineering Technology

NeuroNest: Community based Cognitive Health Monitoring & Early Dementia Detection System

Mr. Ajay Kushwaha, Mr. Mayur Dete, Mr. Shreyas Chavan, Prof. Sneha Sankhe

Dementia represents a major public health concern worldwide, particularly as the global population continues to age. The condition is characterized by a gradual deterioration in cognitive functions including memory retention, reasoning ability, decision making, and language processing. As the disease progresses, individuals experience increasing difficulty performing routine daily activities, which significantly affects their independence and overall quality of life. Early identification of cognitive decline is ess …

31.08.2026journal-article

Frontiers in Aging Neuroscience

Short-term environmental enrichment modulates brain region-specific redox responses in adolescent female mice

Matheus Santos de Sousa Fernandes, Alexandre Kanashiro, Tiago Lacerda Ramos, Danielle Dutra Pereira, Vanessa Lima de Souza, Claudia Jaques Lagranha, Sacide Tüfekci, Burak Yagin, Nouf H. Alkhamees, Fabrício Oliveira Souto

Background Environmental enrichment (EE) is a non-pharmacological intervention known to enhance neuroplasticity and resilience. However, studies of EE on brain redox balance have focused predominantly on males and single regions, leaving the developing female brain and region-specific responses largely uncharacterized. This study investigated the effects of a three-week EE protocol on oxidative balance in the hippocampus, hypothalamus, and brainstem of adolescent female C57BL/6 mice. Methods Lipid peroxidation was …

31.08.2026journal-article

Stanzaleaf International Journal of Multidisciplinary Studies

Role of Artificial Intelligence in Green Human Resource Management: An Integrated Framework for Sustainable People Management

R. Idhenya, Dr. S. Vennillashree

This paper examines the rapidly developing relationship between Artificial Intelligence (AI) and Green Human Resource Management (GHRM). As organizations pursue environmental objectives while digitizing their HR systems, AI is increasingly being considered for recruitment, learning, performance assessment, employee engagement and workforce analytics. The paper argues that the sustainability contribution of AI cannot be inferred from automation alone. A critical review of foundational GHRM scholarship and recent AI- …

31.08.2026journal-article

Frontiers in Dental Medicine

Entrustable professional activities as a framework for longitudinal geriatric oral health curriculum reform in undergraduate dental education

Kiran Kumar Ganji, Shivasakthy Manivasakan, Mohammad Khursheed Alam, Mohammed Katib Alruwaili, Meshal Aber Alonazi, Hmoud Ali Algarni

Population ageing is increasing the complexity of oral health care and creating new expectations for undergraduate dental education. Elder adults increasingly present with multimorbidity, frailty, polypharmacy, functional dependency, cognitive decline, and social vulnerability, all of which require dental graduates to move beyond procedural competence toward integrated, person-centred, and collaborative care. However, the literature continues to show substantial variability and underdevelopment in undergraduate ger …

31.08.2026journal-article

Alzheimer's & Dementia

Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk

Erika Pugh, Muriel Taks Calle, Ganesh M. Babulal, Paris B. Adkins‐Jackson

Abstract INTRODUCTION The social exposome is increasingly recognized as a key determinant for cognitive health. Adverse policing represents an understudied aspect of the social exposome, reflecting persistent encounters with punitive surveillance and law enforcement that accumulate as chronic structural stressors across the life span. METHODS Using data from the Health and Retirement Study (2006–2020), we performed exploratory and confirmatory factor analyses to examine the dimensional overlap between depressive sy …

31.08.2026journal-article

Physiotherapy Canada

A Theory-Based Approach to Adapting a Task-Oriented Community Exercise Programme for Virtual Delivery for People With Balance and Mobility Limitations

Elizabeth L. Inness, Anessa Koussiouris, Navaldeep Kaur, Margot Catizzone, Diane Tse, Gayatri Aravind, Jennifer O’Neil, Lisa Sheehy, Joyce Fung, C. Allyson Jones, Heidi Sveistrup, Nancy M. Salbach

Abstract Purpose: Despite the health benefits for people with mobility limitations of participating in community-based exercise programmes (CBEPs), accessing and implementing in-person CBEPs can be challenging. We describe a theory-based approach to adapting a group task-oriented, in-person CBEP targeting balance and mobility to a virtual format. Method: We used the Knowledge-to-Action and Medical Research Council frameworks to guide adaptation of an established CBEP for virtual delivery. We undertook consultations …

31.08.2026journal-article

Frontiers in Public Health

Associations between DigComp 2.2-based digital competence and multidimensional health literacy among older adult learners in Shanghai Universities of the Third Age: a cross-sectional study

Xindi Shen, Yingyi Luo, Chen Yang, Ouyang Xu, Yangli Wei, Qianqian Ma, Jiayu Cao

Background Digital competence may influence older adults' engagement with health information in increasingly digitalized societies. However, evidence on the association between DigComp 2.2-based digital competence and multidimensional health literacy remains limited. This study examined digital competence levels and its associations with health literacy domains among older adult learners in Shanghai Universities of the Third Age. Methods A cross-sectional study was conducted from September to December 2024 in four …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Nutritional status and dietary adequacy in people living with HIV: a systematic review

Pragya Yadav, Meenakshi Khapre

HIV infection adversely affects nutritional status by increasing metabolic demands, impairing nutrient absorption, and reducing dietary intake. Malnutrition and dietary inadequacy among people living with HIV (PLHIV) contribute to immune suppression, poor treatment response, and accelerated disease progression, yet nutrition remains an underemphasized component of HIV care. This systematic review aimed to assess the nutritional status and dietary adequacy of PLHIV by synthesizing evidence from Indian and internatio …

31.08.2026journal-article

Bhakti Sabha Nusantara

Implementation Of A Simplified Comprehensive Geriatric Assessment And Emergency Warning-Sign Education For Older Adults In An Internal Medicine Outpatient Clinic

Puji Setya Rini

Introduction: Older adults are vulnerable to acute health deterioration due to multimorbidity, functional decline, cognitive impairment, nutritional problems, and fall risk. Comprehensive Geriatric Assessment (CGA) provides a multidimensional approach to identifying geriatric problems and supporting appropriate interventions. This community service program aimed to implement simplified CGA and improve older adults’ knowledge of emergency warning signs. Methods: The program involved 30 older adults attending the Int …