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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

PLOS One

Association between sense of coherence and loss of independence or death in older adults: Locomotive Syndrome and Health Outcomes in Aizu Cohort Study

Sho Matsushita, Hajime Yamazaki, Yoshie Yamada, Yusuke Ogawa, Yosuke Yamamoto

Background Although sense of coherence (SOC) is a core concept to promote healthy aging, evidence of whether SOC improves loss of independence (LOI) or death is lacking. We aimed to investigate the association between SOC and LOI or death in older adults. Methods We enrolled independent older adults aged 65 years or over from a population-based cohort. SOC was assessed using a three-item SOC scale at baseline. The primary outcome was a composite of LOI (defined by Japanese long-term care insurance certification) or …

31.08.2026journal-article

Revista Brasileira Multidisciplinar

Exercícios físicos na mobilidade cervical em pessoas adultas e idosas:

Cyntia Leila Stiz Gessner, Fernanda Souza Tomé da Silva, Braulio Henrique Magnani Branco, Luciana Lozza de Moraes Marchiori

Changes in cervical mobility not only affect the ability to perform simple movements, but also limit more complex functions that disable postural control and balance and generate widespread impacts. The objective of this work was to systematically review studies in the literature that address the therapeutic potential of physical exercises focusing on the mobility of the cervical spine in adults and elderly people. A systematic literature review was carried out with a bibliographic survey of texts published between …

31.08.2026journal-article

Biomedicines

Structural Entropy of Liver Histological Sections as an Integrative Index of Tissue Disorganization in Constant-Light-Induced Hepatic Remodeling with Aging-Associated Features

David A. Areshidze, Nikita S. Gladyshev, Maria A. Kozlova, Anna I. Anurkina

Objective: To evaluate whether structural entropy of liver histological sections reflects tissue disorganization in a rat model of constant light exposure (dark deprivation) and to explore its associations with morphofunctional parameters of hepatic remodeling. Methods: Male Wistar rats (n = 120) were divided into a control group (12:12 h light/dark) and a constant light group (24 h/day, 3 months). Biochemical, histological, immunohistochemical (p16, p21, p53, BMAL1, CLOCK, PER2, Ki-67) and ultrastructural paramete …

31.08.2026journal-article

Revista San Gregorio

Memorias e identidad en Manabí: la historia de Los Tauras y el Pueblo Montuvio

Daniel Yoffre Valdivieso Solórzano

This study analyzes the impact of institutional violence and the actions of Los Tauras on the memory and social structure of the Montuvio communities of Manabí, Ecuador, between the 1930s and the 1960s. A qualitative research design was employed, grounded in oral history and supported by narrative, ethnographic, and hermeneutic approaches. Data were collected through semi-structured interviews, participant observation, and sociodemographic questionnaires administered to eight purposively selected participants. The …

31.08.2026journal-article

Frontiers in Endocrinology

Gender, age, and socioeconomic position-specific associations between illness perception and diabetes-related distress: cross-sectional analysis among people with type 2 diabetes

Elvire N. Landstra, Fleur de Klerk, Dinah van Schalkwijk, Henry Jansen, Lars. L.F.G. Valke, Tom Smeets, Ruth E. Mark, Sabita S. Soedamah-Muthu

Aim Around one-third of people with type 2 diabetes (T2DM) suffer from diabetes-related distress (DRD). Understanding risk factors could aid in targeted interventions to lower distress and improve quality of life. Although the way people perceive their illness – illness perceptions – have been related to DRD, studies so far have been small and it is unclear whether gender, age and socioeconomic position (SEP) affect the association. Therefore, this study aims to investigate the age-, gender-, and SEP-specific relat …

31.08.2026journal-article

Journal of Korean Gerontological Nursing

Factors associated with geriatric nursing performance of nurses in orthopedic units: A cross-sectional descriptive study

Hui Yeong Kim, So Young Shin

Purpose: Nurses in orthopedic units (OUs) play an important role in managing pain, promoting functional recovery, and preventing complications associated with prolonged bed rest in older patients. This study aimed to investigate the factors associated with geriatric nursing performance of nurses in OUs. Methods: The subjects included 131 nurses in OUs from four hospitals in Korea. A structured self-reported questionnaire was administered to assess the subjects’ general characteristics, geriatric nursing stress, res …

31.08.2026journal-article

Ahi Evran Medical Journal

Impact of Anesthesia Type on Mortality and Postoperative Intensive Care Unit Admission in Geriatric Hip Fracture Surgery: A Retrospective Cohort Study

Fadime Tosun, Ufuk Karbaş, Zeliha Bozkurt, Öznur Uludag, Hamza Nakır, Ebubekir Şeramet

Purpose: This retrospective cohort study primarily aims to assess the connection between the type of anesthesia used and in-hospital mortality among elderly patients with hip fractures. Additionally, it seeks to investigate mortality rates post-surgery, at 30 days, and at 1 year, categorized by the need for intensive care (ICU), age groups, and ASA classification.Materials and Methods: Researchers conducted a retrospective analysis of patients who had hip fracture surgery from January 2015 to February 2022, dividin …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Innovative strategies to strengthen geriatric healthcare in India: bridging gaps through digital health and community-based interventions

Pritish Dhal, Subhashree Das, Lisa Sarangi

India is experiencing a demographic shift with a rapidly growing elderly population projected to reach 20% by 2050. However, geriatric healthcare remains underdeveloped and inadequately integrated within the public health system. This article explores the status of elderly healthcare in India, highlighting key gaps in infrastructure, trained human resources, and service delivery. The National Programme for Health Care of the Elderly (NPHCE), though well-intentioned, suffers from limited implementation, particularly …

31.08.2026journal-article

Bioinformation

Mental health crisis and family bonding among the geriatric population in an urban Indian community

Arockia Vinolia Amalraj

Old age in India is associated with increasing mental health concerns and changing family relationships among older adults. Therefore, it is of interest to assess the mental health crisis and family bonding among 60 elderly individuals aged ≥60 years in Choolai, Chennai. Mental health crisis was low in 60.00%, moderate in 23.33% and high in 16.67%, while family bonding was low in 43.33%, moderate in 35.00% and high in 21.67%. A significant negative correlation was found between mental health crisis and family bondi …

31.08.2026journal-article

Journal of Hypertension

Predictors of long-term all-cause mortality and incident disability in older hypertensive outpatients

Giulia Rivasi, Chiara Salucci, Giuseppe D’Ambrosio, Virginia Gori, Marco Capacci, Greta Ceccarelli, Michele Vinci, Vincenzo Giosuè Giambusso, Alessandra Liccardo, Maria Francesca Bisignano, Lorenza Rossi, Giulia Spanalatte, Eleonora Rizzi, Enrico Mossello, Andrea Ungar

Objective: In previous studies involving older hypertensive adults, geriatric conditions with potential prognostic impact and outcomes of geriatric relevance (e.g., disability) remained largely unexplored. This study investigated predictors of all-cause mortality and incident disability in a real-world sample of older hypertensive outpatients undergoing comprehensive geriatric assessment. Methods: We analyzed data from the longitudinal HYPER-FRAIL pilot study, involving hypertensive outpatients ≥75 years undergoing …

31.08.2026journal-article

Iberoforum. Revista de Ciencias Sociales

Participación comunitaria y bienestar en mujeres mayores en un barrio urbano de la periferia de Valencia, España

Karla Daniela González Saldaña, Sacramento Pinazo-Hernandis

El presente estudio analiza cómo una intervención comunitaria participativa contribuye a la construcción y sostenibilidad de redes de apoyo entre mujeres mayores, así como a sus efectos en el bienestar socioemocional y el sentido de pertenencia. Se realizó un estudio de caso con diseño mixto cualitativo-cuantitativo en el barrio de La Creu del Grau (Valencia, España), con diez mujeres de 61 a 91 años. La intervención, con metodología de investigación-acción participativa, consistió en diez sesiones orientadas a pro …

31.08.2026journal-article

Wasathiyyah

Taghlidh al-Uqubah and Reverse Proof: Criminal Law Protection of People with Disabilities Perspective Maqashid al-Syariah

Wiwin Nur Jannah, Khairunnisa, A. Muhyiddin Khotib

Indonesia's criminal justice system fails to provide proportional justice for disabled victims due to strict evidentiary requirements in Article 183 KUHAP and standardized sentencing in the KUHP that ignores victim vulnerability. Employing a normative legal approach grounded in maqāṣid al-Sharīʿah, this study formulates a legal reconstruction to resolve these systemic deadlocks through a dual breakthrough. First, it addresses evidentiary barriers by introducing the reversal of the burden of proof via qiyās al-awlā; …

31.08.2026journal-article

Global Discourse

Supporting people with additional needs and obligations: universal basic income and workplace equity for disabled people and informal carers

Lucy Burke

This article explores some of the challenges presented by the implementation of universal basic income (UBI) for disabled people, including its potential implications for access to employment and income security. The question of a ‘job guarantee’, which is often presented as a mechanism to mitigate the assertion that UBI will somehow facilitate free-riding or the liberation of idleness in an apparently work-shy population, raises significant questions when explored in relationship to disabled people, who are alread …

31.08.2026journal-article

Alzheimer's & Dementia

Regional ventricular enlargement as an in vivo biomarker of cumulative biomechanical neurodegeneration in former American football players

Brian Szekely, Jared Stearns, Anya S. Mirmajlesi, Rebecca D. Folkerth, Sylvain Bouix, Daniel H. Daneshvar, Charles H. Adler, Charles Bernick, Laura J. Balcer, Jeffrey L. Cummings, Eric M. Reiman, Robert A. Stern, Martha E. Shenton, Richard J. Rushmore, Hector Arciniega, for the DIAGNOSE CTE Research Project

Abstract INTRODUCTION Repetitive head impacts (RHIs) have been linked to later life neurodegeneration, yet the in vivo structural correlates of cumulative biomechanical loading remain unclear. We examined whether regional ventricular morphology in former American football players reflects exposure burden and traumatic encephalopathy syndrome (TES) classification. METHODS Participants included 170 male former football players and 54 age‐matched asymptomatic male controls from the Diagnostics, Imaging, and Genetics N …

31.08.2026journal-article

Innovation in Aging

The bidirectional relationship between depression and cognitive function in older adults: Evidence from a psychosocial intervention on late-life depression

Lucy Xi Lu, Dara Kiu Yi Leung, Stephanie Ming Yin Wong, Wai Chi Chan, Gloria Hoi Yan Wong, Terry Yat Sang Lum

Abstract Background and Objectives Depression is a modifiable predictor of dementia, but the effects of addressing depression to improve cognition, especially psychosocial interventions, are understudied. The underlying relationships between depressive symptoms (DS) and cognitive function (CF) are also unclear. Most prior research has been observational, lacking insight into their interactions during interventions. This study examined the longitudinal relationships between DS and CF across psychosocial intervention …

31.08.2026journal-article

Journal of Applied Gerontology

Living Well at Home With Dementia: Home Modifications, Caregiving Duration, and Subjective Well-Being

Soobin Park, Eunsun Kwon, Sojung Park, Oejin Shin, Sehyun Baek

Background Supporting people with dementia to live well at home requires balancing safety with emotional well-being. Although home modifications are promoted to enhance independence, their implications for subjective well-being remain unclear. Objective This study examined associations between home modifications, caregiving duration, and subjective well-being among community-dwelling older adults with dementia, informed by the Ecological Theory of Aging. Methods Using data from five NHATS waves (2015–2019), we cond …

31.08.2026journal-article

The Korean Gerontological Research Society

Social Frailty Components and Mortality in Korean Older Adults Controlling for Physical Frailty: Analysis of the Korean Longitudinal Study of Ageing(2006-2024)

Ilsung Nam

This study examined whether social frailty operates as a single construct or whether its components differ in their association with mortality among Korean older adults. Using the Korean Longitudinal Study of Ageing (KLoSA, 2006–2024), 4,164 adults aged 65 or older at baseline were followed. Mortality excluding external causes (injury and accidents), which are unlikely to reflect social aging, was modeled with Cox proportional-hazards regression. Social frailty was measured by five components-social support deficit …

31.08.2026journal-article

Archiv Euromedica

COLLAGEN SUPPLEMENTATION AND TISSUE HEALTH IN MIDDLE-AGED AND OLDER ADULTS: A NARRATIVE REVIEW OF CLINICAL EVIDENCE

Aleksandra Maria Błoch, Natalia Rządzińska, Kornelia Julia Fimiarz, Aleksandra Olga Pakulska, Maria Anna Miller, Aleksandra Jolanta Kamińska, Aleksandra Katarzyna Kłosowicz

Background Collagen is the principal structural protein of connective tissues, including the skin, cartilage, tendons, bone, and blood vessels. Ageing is associated with changes in collagen synthesis, organisation, cross-linking, and degradation, which contribute to reduced tissue integrity and function. Collagen supplementation has therefore been investigated as a nutritional strategy to support tissue health in middle-aged and older adults. Aims This narrative review aimed to summarise current evidence on the phy …

31.08.2026journal-article

Gazi Sağlık Bilimleri Dergisi

AGING BEYOND NUMBERS: THE ASSOCIATION BETWEEN POPULATION AGING AND COST-RELATED HEALTHCARE ACCESS IN OECD COUNTRIES

Zeliha Köse, Kenan Kıbıcı

Background: This study examines the association between population aging and cost-related healthcare access across OECD countries. Methods: An unbalanced panel dataset comprising 102 country-year observations from 15 OECD countries over the period 2000–2023 was analyzed. Fixed-effects and random-effects models with standard errors clustered at the country level were estimated. Based on the Hausman test, the random-effects model was retained as the preferred specification. Results: In the preferred random-effects mo …

31.08.2026journal-article

Neuro-Cell Molecular Research

Evaluation of Anemia in Geriatric Patients Treated at Bingol State Hospital in 2017

Emine Aydin Bayat, Okan Arihan, Özlem Ergul

Anemia is a worldwide health problem. The aim of the study was to determine how anemia was affected by sociodemographic characteristics and factors such as treatment in hospital, and to evaluate anemia according to morphological, age groups and anemia severity level in individuals with anemia. The study was conducted retrospectively in geriatric patients admitted to Bingöl State Hospital. The incidence of anemia was determined in both inpatients and outpatients, and in men and women. Patients with anemia were class …

31.08.2026journal-article

Alzheimer's & Dementia

Female vulnerability to microvascular transport dysfunction emerges early across the Alzheimer's disease continuum

Manxi Xu, Yian Gao, Peiling Ou, Haoyu Yang, Jia Wang, Wulong Liu, Ni Shu, Yu Sun, Liping Fu, Lidia Glodzik, Tracy A Butler, Gloria C Chaing, Yi Li, Yi Wang, Liangdong Zhou, Guolin Ma

Abstract INTRODUCTION We tested whether quantitative transport mapping (QTM)‐derived perfusion velocity would detect earlier and more sex‐specific microvascular alterations than cerebral blood flow (CBF) across the Alzheimer's disease (AD) continuum. METHODS In 182 participants (cognitively normal = 53, subjective cognitive decline [SCD] = 48, mild cognitive impairment [MCI] = 31, AD = 50), seven‐delay arterial spin labeling was used to derive CBF and QTM velocity. Age/sex‐adjusted models assessed diagnostic and se …

31.08.2026journal-article

International Journal of Molecular Sciences

MIF Promoter Variant rs755622 (−173G/C) in Younger and Older Turkish Adults: An Exploratory Cross-Sectional Genetic and In Silico Analysis

Kursat Ozdilli, Gozde Oztan, Yeliz Ogret, Rustu Oguz, Hayriye Senturk Ciftci, Filiz Aydın, Fatma Oguz

Age-associated immune–inflammatory remodeling may be influenced by regulatory variation in the macrophage migration inhibitory factor gene (MIF). We conducted an exploratory cross-sectional comparison to assess whether MIF rs755622 (−173G/C) genotype distributions differ between predefined younger and older age groups in a Turkish population and to characterize the observed pattern using genetic-model and in silico analyses. We evaluated 368 individuals: 245 older adults aged 65–102 years and 123 younger controls a …

31.08.2026journal-article

Clocks & Sleep

HRV-Based Respiratory-Rate Estimation in Older Adults: Error Modeling and Pilot Validation for Wearable Sleep Monitoring

Emi Yuda, Naoya Morikawa, Junichiro Hayano

Respiratory frequency is a critical biomarker in sleep medicine and circadian biology. We investigated whether the high-frequency (HF) component of heart-rate variability (HRV)—which reflects respiratory sinus arrhythmia (RSA)—can serve as a non-invasive proxy for breathing rate estimation from ECG or PPG. We employed a two-stage validation design: (1) a physiologically calibrated simulation study (N = 30 per condition, five conditions, 180 s recordings) for controlled error characterization using the PhysioNet ECG …

31.08.2026journal-article

Diseases

Safety and Exploratory Pre–Post Changes Associated with an Orally Disintegrating Three-Strain Probiotic Tablet in Older Adults with Functional Constipation: A Single-Center, Open-Label, Single-Arm Study

Daisuke Asaoka, Tsutomu Takeda, Yasuhisa Jimbo, Eiji Kamba, Yusuke Nomoto, Osamu Nomura, Daiki Abe, Kumiko Ueda, Hiroya Ueyama, Hiroyuki Isayama, Mariko Hojo, Akihito Nagahara

Background/Objectives: Functional constipation is common in older adults and impairs quality of life. Evidence for multi-strain orally disintegrating (OD) probiotic formulations in this population remains limited. Methods: In this single-center, open-label, single-arm pre–post study, adults aged 65–90 years meeting the Rome IV criteria for functional constipation were administered an OD tablet containing Bacillus subtilis TO-A, Enterococcus faecium T-110, and Clostridium butyricum TO-A for 8 weeks. The primary endp …