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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

Lecture Notes in Education Psychology and Public Media

The Theoretical Origin of Adhering to People-Centeredness in Ideological and Political Education in the New Era —An Investigation Based on Marxist Classic Texts

Shuyuan Hao

The people-centeredness advocated by ideological and political education has profound Marxist theoretical origins, and its core essence is consistent with Marx and Engels' theories on human beings. Adhering to people-centeredness in ideological and political education in the new era represents the dialectical unity of logical starting point and logical destination: taking "free and conscious human beings" as the logical starting point, it requires ideological and political education to respect human subjectivity, c …

03.09.2026journal-article

International Journal of Rheumatic Diseases

Cross‐Sectional and Longitudinal Association Between Biological Aging Acceleration and the Risk of Osteoarthritis: A Cohort Study From UK Biobank

Sisi Liu, Weishu Wang, Chengxu Li, Yuxin Lai, Zhounan Zhou, Menglin Han, Yujie Zhang, Yan Zhang, Ke Tang, Haitao Sun, Qian Yang, Muhui Zeng, Tianxiang Fan, Zhong Alan Li, GO Consortium, Changhai Ding, David J. Hunter, Zhaohua Zhu

ABSTRACT Objective To evaluate the relationship between biological ages and the prevalence and incidence of osteoarthritis (OA). Methods 332 261 participants from UK Biobank were analyzed. Biological aging was measured using phenotypic age (PhenoAge) and Klemera–Doubal (KDMAge). KDMAge was derived from nine clinical biomarkers to gauge system integrity decline, while PhenoAge was computed from chronological age and nine clinical biomarkers to gauge mortality risk. Biological aging accelerations were computed as res …

01.09.2026journal-article

Healthcare

Understanding Well-Dying Research in a Rapidly Aging Society: A Text Network and Topic Modeling Analysis of Korean Academic Publications

Jin-Hui Ku, Kwang-Hwan Kim

Background/Objectives: Population aging has emerged as a major global challenge, particularly in Asian countries experiencing rapid demographic transitions. Among them, South Korea represents one of the fastest aging societies in the world, having rapidly transitioned into a super-aged society. As aging populations expand worldwide, increasing attention has been directed toward well-dying as an important component of quality of life, end-of-life care, and social well-being in later life. This study aims to identify …

04.09.2026journal-article

International Journal of Geriatric Psychiatry

Dementia Risk After Glaucoma Surgery and Medical Therapy: A Multicentre Real‐World Cohort Study

Lee‐Yuan Lin, Jie‐Syuan Wu, Wei‐Jung Jeng, Chen‐Hsin Tsai, Shu‐Yu Liu, Tsai‐Wei Huang, Fara Silvia Yuliani, Shyh‐Hsiang Lin

ABSTRACT Background and Purpose Glaucoma, a neurodegenerative optic neuropathy and leading cause of irreversible vision loss, shares vascular and neurodegenerative mechanisms with dementia. The 2024 Lancet Commission newly identified visual impairment as a modifiable dementia risk factor. As glaucoma management ranges from long‐term medical therapy to laser/surgical intervention, it remains uncertain whether treatment modality influences long‐term systemic outcomes such as dementia. This study compares dementia ris …

01.09.2026journal-article

Journal of Transportation Engineering, Part B: Pavements

Impact of Wetting and Drying Cycles on Reclaimed Asphalt Pavement and Warm Mix Asphalt Performance: Comparison with Long-Term Aging Conditions for Pavement Durability

Kumari Monu, Surya Kant Sahdeo, Gondaimei Ransinchung Rongaimei Naga

Abstract The primary objective of this study was to evaluate the effect of reclaimed asphalt pavement (RAP) and warm mix asphalt (WMA, Sasobit) combinations on moisture susceptibility, fatigue resistance, rutting behavior, Marshall stability, and aging of bound base-course mixes. Two RAP sources (from pavements with different service lives) were incorporated at ≈ 35 % and ≈ 70 % by mix mass, and mixtures were produced as hot mix asphalt (HMA) and WMA. Specimens were conditioned under two environmental regimes’ stan …

01.09.2026journal-article

JMIR mHealth and uHealth

Correction: Effects of Telehealth Interventions for People With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Minyue Sun, Fuyou Tang, Luo min, Shiyu Wen, Shuang Wang, Huiping Jiang

In the originally published version of this article, the designation for co-first authors was inadvertently omitted. The author list and footnote should be corrected as follows: Corrected Author Line:​ Minyue Sun¹, Fuyou Tang²*, Luomin¹, Shiyu Wen¹, Shuang Wang¹, Huiping Jiang¹ (Note: The asterisks (*) denote co-first authors) Corrected Footnote:​ * These authors contributed equally to this work. All other aspects of the article remain unchanged.

01.09.2026journal-article

Nutrition & Dietetics

“Hello, these people exist”: Examining dietitians' perspectives, approaches, and experiences in transgender and gender diverse health

Majella Jones, Christie Bennett, Julia McCartan, Janeane Dart

Abstract Aim The lack of research and guidelines on transgender and gender diverse health, including nutrition considerations, contributes to negative health outcomes for transgender and gender diverse people. This study sought to examine dietitians' perspectives, knowledge, and experiences regarding transgender and gender diverse health dietetic practice. Methods This critical inquiry study recruited dietitians globally. Data collection involved online surveys and interviews. At survey completion, consenting dieti …

01.09.2026journal-article

Nutrients

Sex Modifies the Association Between Planetary Health Diet Adherence and Kidney Function Decline in US Adults Aged 50 Years and Older

Guido Gembillo, Luca Soraci, Alberto La Spada, Paolo Fabbietti, Claudia Lo Re, Maria Federica Ricca, Andrea Corsonello, Domenico Santoro

Background/Objectives: Diet is a modifiable determinant of kidney health, and sex differences in kidney physiology support sex-specific evaluation of dietary patterns. We examined the association of Planetary Health Diet Index (PHDI) adherence with cystatin C-based eGFR decline, and its modification by sex, in US adults aged 50 years and older. Methods: We analyzed 2126 Health and Retirement Study participants (950 men, 1176 women) with diet assessed by food frequency questionnaire in 2013 and cystatin C-based eGFR …

02.09.2026journal-article

BMJ Open

Mapping longitudinal evidence on multidimensional frailty among community-dwelling older adults: protocol for a scoping review

Mi-So Shim, Gaya Kim, Somyee Min

Introduction Multidimensional frailty among community-dwelling older adults has emerged as an important issue in ageing research, given its close association with declines in health status, functional independence and overall quality of life. This scoping review aims to map longitudinal evidence on multidimensional frailty in community-dwelling older adults, including its measurement, prevalence, changes over time and associated risk factors. The findings will be used to generate insights for future research and in …

01.09.2026journal-article

Clinical Infectious Diseases

Direct Initiation of Long-Acting Cabotegravir Plus Rilpivirine in People with HIV and Suboptimal Virologic Suppression: A Randomized Trial

Nan-Yu Chen, Cheng-Pin Chen, Yi-Chun Lin, Shu-Hsing Cheng, Shien-Shian Huang, Jun-Yuan Zheng, Ching-Tai Huang, Ting-Shu Wu, Ting-Yi Su, Shian-Sen Shie, Jung-Jr Ye, Chun-Fu Yeh, Peng-Hao Chang, Chong Kei Lao, Shu-Yuan Li, Yu-Hsiang Hsiao, Zhuo-Hao Liu, Chien-Yu Cheng

Abstract Background Long-acting injectable cabotegravir plus rilpivirine (LA CAB+RPV) is approved for virally suppressed people with human immunodeficiency virus (HIV), but evidence for its use in those with persistent viremia and adherence challenges remains limited. Methods We conducted a multicenter, open-label, randomized study involving oral antiretroviral therapy (ART)-experienced people with HIV who had been diagnosed with HIV for at least 12 months and a most recent HIV-1 RNA level of at least 200 copies pe …

01.09.2026journal-article

Sexually Transmitted Diseases

An exploratory intersectional analysis of lifetime syphilis prevalence among people who inject drugs in Montreal, Canada

Brendan L. Harney, Julie Bruneau, Valérie Martel-Laferrière, Sarah Larney

Background: Syphilis cases have increased among women and heterosexual men in Canada and people who inject drugs (PWID) are an emerging group at risk of infection. We aimed to examine syphilis prevalence among PWID stratified by men and women, and differences according to intersecting population groups, socio-structural factors and sexual and substance use behaviors. Methods: Data were from HEPCO, a community-based cohort study of PWID in Montreal. We tested for syphilis (lifetime and active) via treponemal testing …

01.09.2026journal-article

International Journal of Integrated Care

Protecting or Excluding? Ethical Tensions in Integrated Care Research with People with Complex Needs

Catherine Hudon, Marie-Dominique Poirier

This perspective paper draws on our experience as a clinician researcher and a patient partner involved in the implementation and evaluation of an integrated care program for people with complex needs. Although an organization actively engaged in integrated care agreed to participate in a research project evaluating implementation, no patient referrals were ultimately received from case managers. Using a real-world vignette, we examine how well-intentioned protective practices within integrated care settings can le …

01.09.2026journal-article

Alzheimer's & Dementia

Brain‐derived plasma p‐tau217 shows enhanced dynamic range for Alzheimer's disease neuropathological change

Marisa N. Denkinger, Wagner S. Brum, Antoine Leuzy, Alpana Singh, Taina M. Marques, Valentina Ghisays, Hillary Protas, Yi Su, Ali Atri, Thomas G. Beach, Geidy E. Serrano, Kinal Bhatt, Corey M. Carlson, Katharine Hoffmann, Eric M. Reiman, Nicholas J. Ashton

Abstract INTRODUCTION Plasma phosphorylated tau (p‐tau), particularly p‐tau217, is a highly specific biomarker of Alzheimer's disease (AD) pathology. However, plasma p‐tau217 can be elevated in rare non‐AD conditions. Brain‐derived (BD) p‐tau217 may reduce these off‐target effects, but its performance against neuropathology has not been evaluated. METHODS We compared p‐tau217, BD p‐tau217, their amyloid beta 42 (Aβ42) ratios, BD p‐tau217/p‐tau217, and BD p‐tau217/BD tau in end‐of‐life plasma from 288 neuropathologi …

01.09.2026journal-article

Journal of Intelligence

Effects of Combined Physical and Cognitive Stimulation on Go/No-Go Performance in Older Women: A Pilot and Feasibility Study

Mauricio Barramuño-Medina, Pablo Valdés-Badilla, Pablo Aravena-Sagardia, Jordan Hernandez-Martínez, Edgar Vásquez-Carrasco, Esteban Fariña-Hermosilla, Wilson Pastén-Hidalgo, Germán Gálvez-García

This study aimed to examine within-subject changes associated with a 12-week multicomponent training program combined with cognitive stimulation in cognitive–motor performance in older women, and to evaluate changes in cognitive status and health-related quality of life (HRQoL). Thirty-three participants aged 70.24 (4.32) years were assessed at baseline, 6 weeks, and 12 weeks. Cognitive–motor performance was evaluated using a Go/No-Go task, including reaction time (RT), omission errors, and commission errors. Cogni …

01.09.2026journal-article

Journal of Dementia and Alzheimer's Disease

MicroRNAs as Diagnostic Biomarkers for Alzheimer’s Disease and Related Dementias

Manivannan Subramanian, Aditi Singh, Amit Singh

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of late-life dementia. As pathology spreads through the brain, affected individuals experience devastating cognitive decline, linguistic impairments, mood changes, and behavioral issues. Developing effective disease-modifying therapies remains a persistent challenge because diagnosis typically occurs at a late stage, long after extensive, irreversible neuronal and synaptic loss has taken place. To overcome these diagnostic an …

01.09.2026journal-article

Journal of Alzheimer’s Disease

The association between retinal vascular occlusions and dementia using TriNetX

Michelle A. Spratt, Millen S. Khangura, Ambika Manhapra, Audrey Gao, Nicole H. Siegel, Vasiliki Poulaki, Steven Ness, Manju L. Subramanian

Background Retinal vascular occlusions have been associated with higher incidence of dementia and may serve as clinical indicators for underlying cognitive disease. Objective This study investigated whether retinal vascular occlusion and their subtypes are linked to increased risk of dementia, including all-cause dementia, Alzheimer's disease (AD), and vascular dementia (VaD). Methods Participants age 65 and over were categorized into eight groups using the TriNetX global database: 1) Retinal vascular occlusion, 2) …

01.09.2026journal-article

Journal of Public Health and Development

Factors predicting self-protective behaviors against PM2.5 exposure among rural community-dwelling older adults in the Central Region of Thailand: A cross-sectional study

Winthanyou Bunthan, Anchalee Ngamchantratip, Pirunlak Jitdorn, Jariyawat Kompayak

Health problems resulting from exposure to Particulate Matter 2.5 (PM2.5) have been increasing rapidly, especially among vulnerable groups such as older adults. This cross-sectional survey research aimed to examine the level of self-protective behaviors and the factors predicting such behaviors against PM2.5 exposure among 885 rural community-dwelling older adults in the central region of Thailand. The research instruments consisted of three parts: 1) a demographic questionnaire for older adults including related m …

01.09.2026journal-article

Dentistry Journal

Advancing Geriatric Dental Education: A Scoping Review of Barriers and Facilitators in Undergraduate Curricula

Alice Kit Ying Chan, Lindsey Lingxi Hu, Joanna Cheuk Yan Hui, Chun Hung Chu

Background: Geriatric dentistry prepares dentists to care for an aging population. Yet, its integration into undergraduate curricula remains inconsistent. Objectives: To map evidence on the barriers to and facilitators of the implementation and development of undergraduate geriatric dental education. Methods: A scoping review was conducted using systematic searches of PubMed, Scopus, and Embase for English-language original research articles published from 1 January 2016 onward. Two reviewers screened titles, abstr …

01.09.2026journal-article

Historical Ethnology

Jewelry of the Buzuluk Chuvash people from the mid-19th – first third of the 20th century (Based on materials from the Russian Museum of Ethnography)

Nataliya Yu. Kashpar

The presented article is based on materials from the Russian Museum of Ethnography. It examines jewelry worn by the Chuvash people of the Buzuluk ethno-territorial group, which formed in the Buzuluk and southern part of the Buguruslan districts of the Samara province in the second half of the 18th and 19th centuries. The museum collection represents all the main types of jewelry of this group (over 60 items), making it a comprehensive source for research. Utilization of new materials discovered in the museum collec …

03.09.2026journal-article

CNS Neuroscience & Therapeutics

Melatonin Improves Cognitive Function and Suppresses Excessive Mitophagy in Rats With Vascular Dementia

Si‐jia Hou, Xing‐yi Guo, Zhi‐gang Wang, Ting‐yan Chen, Yang Li, Sui‐yi Xu

ABSTRACT Aims Melatonin has shown neuroprotective potential in various models of cerebrovascular diseases, but its effects on mitophagy in vascular dementia (VaD) induced by chronic cerebral hypoperfusion (CCH) remain unclear. Methods Eighteen adult male Sprague–Dawley rats underwent bilateral common carotid artery occlusion (BCCAO) to induce CCH. Animals were randomly assigned to three groups ( n = 6 per group): sham‐operated controls, BCCAO model animals receiving vehicle injection, and BCCAO animals treated with …

01.09.2026journal-article

Circulation

Vacuolar H + -ATPase Preserves Cardiolipin Homeostasis Through the Lysosomal-Mitochondrial Axis to Restrain Cardiac Aging

Hongtao Tie, Mengqian Hou, Yumeng Li, Min Pan, Dietbert Neumann, Ruimin Liu, Jun Zhang, Martijn F. Hoes, Miranda Nabben, Jan F.C. Glatz, Xi Li, Xin Wu, Joost J.F.P. Luiken, Shujin Wang

BACKGROUND: Cardiac aging involves progressive mitochondrial dysfunction, contributing to heart failure. Cardiolipin (CL), essential for mitochondrial function, is increasingly depleted in aging cardiomyocytes, promoting mitochondrial decline. Lysosomal degradation relies on v-ATPase (vacuolar-type H+-ATPase)–mediated acidification, and although lysosomes regulate phospholipid metabolism, their roles in CL homeostasis during aging remains unclear. This study examines whether v-ATPase dysfunction drives age-related …

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01.09.2026journal-article

Saudi Journal of Kidney Diseases and Transplantation

Chronic Dehydration in Older Adults: A Silent Threat to Healthy Aging

Tej K. Mattoo, Hong Lu

Abstract In contrast to acute dehydration, which is usually recognized through identifiable risk factors, clinical signs, and laboratory abnormalities, chronic dehydration develops insidiously and frequently goes unrecognized. This is particularly true in older adults, among whom many of its nonspecific manifestations—such as weakness, constipation, headache, dizziness, gait instability, and confusion—are often mistakenly attributed to normal aging. This population is especially vulnerable to chronic dehydration be …

01.09.2026journal-article

The Gerontologist

“The right to be heard: exploring epistemic injustice in dementia care. A qualitative study”

Lara Calabrese, Marco Brigiano, Martina Quartarone, Alice Annini, Elisa Ferriani, Stefania Martinelli, Lisa Bortolotti, Rabih Chattat

Abstract Background and Objectives Epistemic injustice, introduced by philosopher Miranda Fricker in 2007, refers to harm affecting individuals as knowers because of social prejudices and stereotyping. This leads to the partial or complete exclusion of certain individuals from knowledge building. People living with dementia are particularly vulnerable because cognitive impairments may reinforce assumptions about reduced credibility, marginalising their voices in clinical, social and family contexts and limiting opp …

01.09.2026journal-article

Journal of the American Heart Association

Amyloid‐Related Imaging Abnormalities Summit Special Proceedings: Cardiovascular and Stroke Considerations for β‐Amyloid Immunotherapy in Alzheimer Disease

Steven M. Greenberg, Costantino Iadecola, Sherry H.‐Y. Chou, Petrice M. Cogswell, Mitchell S. V. Elkind, William J. Hicks, Caitlin Le, Deborah A. Levine, Richard Lipton, Lauren Massimo, Stephanie M. Mohl, Sudha Seshadri, Heather M. Snyder, Kristine Yaffe, Kori S. Zachrison, Robert Adams, Marc Agronin, Alireza Atri, Mary Ann Bauman, James L. Bernat, Alessandro Biffi, Sonja Blum, Thierry Bussiere, Tara C. Carlisle, Maria C. Carrillo, Gloria Chiang, Kenrick Cato, Alexander Chaitoff, Suzanne Bakken, Matthew W. Schelke, Salvador Cruz‐Flores, Janice Y. Chyou, Colin Derdeyn, Amar Dhand, David A. Evans, Cameron Gettel, Larry B. Goldstein, Joshua Grill, Makoto Ishii, Ambar Kulshrestha

Background New antiamyloid therapies (AAT) for treating patients with early Alzheimer disease (AD) have become available in the past 3 years. Although AAT can be beneficial in slowing progression of AD, they also come with potentially serious side effects, particularly for patients requiring anticoagulation or thrombolysis for cardiovascular conditions. Given that most patients with AD are older and likely to have cardiovascular risk factors, there is urgent need for additional guidance for clinicians about potenti …