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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Neurology

Pediatric stroke in inborn errors of metabolism: clinical characteristics, neuroimaging features, and short-term outcomes

Javeria Raza Alvi, Areeba Wasim, Saher Gul Ahdi, Tipu Sultan, Muhammad Zia-ur-Rehman, Khalid Al-Thihli, Fathiya Al Murshedi, Amna Al Futaisi

Introduction Pediatric stroke has a broad etiological spectrum, with inborn errors of metabolism (IEM) increasingly recognized as an important and potentially treatable cause. This study aimed to characterize the clinical, radiological, and electroencephalographic features of IEM-related pediatric stroke and to evaluate short-term functional outcomes. Methods This prospective cohort study was conducted at The Children’s Hospital Lahore, Pakistan, and Sultan Qaboos University Hospital, Muscat, Oman (January 2024–Dec …

03.09.2026journal-article

LAW AND BUSINESS

Legal Regime of the Circulation of Digital Financial Assets: A Comparative Legal Analysis

Danil R. Bogachev, Aleksandr S. Kiselev

The introduction of digital technologies into many economic processes is changing the functioning principles of many government institutions. This process requires regulatory regulation of newly emerged economic relations and their proper registration and legal protection. The issues of developing information relations in the sphere of turnover of the Central Federal District are related to economic, political, social and other factors that are taken into account in strategic planning, including the national securi …

03.09.2026journal-article

Revista de Ciencias Tecnológicas

Análisis de riesgo a la salud humana por ingesta de arsénico presente en agua purificada en Zinapécuaro, Michoacán: Un enfoque probabilístico

Alexis Calderón Herrera, Marco Antonio Martínez Cinco, José Leopoldo Mendoza Lagunas, Laura Nelly Rodríguez Cantú, María Mercedes Meza Montenegro, María del Mar Navarro Farfán, Jesús Ávila Guzmán

El arsénico (As) como elemento tóxico se encuentra de manera natural regiones geotérmicas de México. En el área de Zinapécuaro, ubicado en Michoacán se han detectado concentraciones que superan la norma de salud de 10 μg/L, particularmente en las aguas subterráneas y de manantial. En este estudio se realizó el muestreo en 6 diferentes negocios de recarga de agua para determinar las concentraciones de arsénico inorgánico presente. El objetivo del trabajo es evaluar el riesgo para la salud humana, particularmente en …

03.09.2026journal-article

An Idea Health Journal

Factors Associated the Perceived Effectiveness of Seven-Jumps Problem with Based Learning Tutorials among Nursing Students: A Mixed-Methods Study

Ika Purnamasari, Candra Dewi Rahayu, Anisa Ell Raharyani

Background: Seven-Jumps Problem-Based Learning (PBL) tutorials are commonly implemented in nursing education to foster active learning, critical reasoning, and collaborative problem-solving. However, evidence on factors influencing students’ perceptions of tutorial effectiveness remains limited in Indonesian nursing education. Methods: An explanatory sequential mixed-methods design was employed. The quantitative phase included 70 fourth-semester undergraduate nursing students and utilized the Tutorial Group Effecti …

03.09.2026journal-article

Advances in Operation Research and Production Management

The impact of board digital cognition on the execution quality of corporate ESG strategy

Shuhao Chen

Against the background of deep integration between digital transformation and ESG governance, corporate ESG strategy no longer remains at the level of responsibility disclosure or image construction. It is gradually shifting toward target decomposition, resource allocation, process supervision, and performance improvement. As the core body of strategic decision-making and governance supervision, the board affects how firms understand ESG data, risk information, and execution processes through its level of digital c …

03.09.2026journal-article

Health Promotion Journal of Australia

Food Processing Knowledge in Relation to Healthiness and Self‐Reported Understanding of the Health Star Rating in Australia

Jacqueline Penney, Tailane Scapin, Adrian J. Cameron, Christine M. White, David Hammond, Clara Gomez‐Donoso

ABSTRACT Issue Addressed This study aimed to examine Australians' food processing knowledge in relation to food healthiness and self‐reported understanding of the Health Star Rating (HSR), their association, and sociodemographic differences. Methods An online survey was completed by 3760 adults in Australia as part of the 2021 International Food Policy Study. Participants rated the healthiness of foods across four categories (grains, meat, dairy, fish), with three products presented per category representing increa …

03.09.2026journal-article

Frontiers in Public Health

Staff-mediated doll therapy in Chinese residential dementia care: an exploratory pilot and feasibility mixed-methods cluster randomized clinical trial

Zhenti Cui, Rongrong Guan, Tianrui Xue, Yongchang Sun, Maw Pin Tan, Mas Ayu Said, Yingdong Cao

Background Doll therapy is a person-centered intervention for behavioral and psychological symptoms of dementia, but evidence from Chinese nursing homes and information about implementation, medication use, and ethical acceptability remain limited. Methods We conducted an exploratory pilot and feasibility mixed-methods cluster-randomized clinical trial in six nursing homes in Zhengzhou, China. Homes were randomized 1:1 to a staff-mediated doll-therapy care package plus routine care or routine care alone. Residents …

03.09.2026journal-article

Frontiers in Public Health

Physical activity perceptions, barriers, and needs among nursing home residents: an explanatory sequential mixed-methods study

Jung-A. Kim, Haeyeon Kim, Hye-Young Jang

Background/objectives Physical activity is essential for maintaining health and preventing functional decline among older adults residing in nursing homes. However, engagement in physical activity remains suboptimal in this population due to multifactorial influences. This study aimed to examine the perceptions, barriers, and needs related to physical activity among nursing home residents. Methods An explanatory sequential mixed-methods design was employed from September to December 2024. In the quantitative phase, …

03.09.2026journal-article

Frontiers in Medicine

Clinical efficacy of the Galdakao-modified supine Valdivia position vs. the lithotomy position in FANS-UAS-assisted IPC-RIRS for renal calculi

Qiuhua Zhu, Yunxia Cai, An Wang, Jiansheng Xiao, Leming Song, Tairong Liu, Hua Chen

Objective To evaluate the clinical efficacy and safety of a modified Galdakao-modified supine Valdivia (GMSV) position combined with a flexible and navigable suction ureteral access sheath (FANS-UAS) in intelligent pressure-controlled retrograde intrarenal surgery (IPC-RIRS) for the treatment of renal calculi. Methods This single-center retrospective cohort study included 158 patients with renal calculi who underwent FANS-UAS-assisted IPC-RIRS between June 2023 and June 2025. Patients were categorized into the GMSV …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Novel predictors of late recurrence after catheter ablation for atrial fibrillation: from biomarkers to artificial intelligence models

Chiyu Chen

Atrial fibrillation (AF) is the most common sustained arrhythmia, and catheter ablation is an established rhythm-control strategy. However, late atrial arrhythmia recurrence remains common, limiting long-term procedural benefits. This review provides a structured and critical overview of current evidence on the predictors of late recurrence after AF catheter ablation across four domains: circulating biomarkers, imaging and electrophysiological substrate markers, genetic susceptibility, and artificial intelligence a …

03.09.2026journal-article

Frontiers in Psychology

When chatbots are perceived as “understanding”: a study on how virtual agent persona styles and affective interaction promote mental health acceptance

Qi Wu, Shizhu Lu, Yuqi Yan, Lin Liu, Xiaojie Peng

Introduction Mental health challenges among university students have become increasingly prevalent, while existing digital interventions often struggle to sustain user engagement and provide meaningful emotional support. Although previous studies have proposed various explanations for the limited acceptance of AI-based mental health chatbots, the role of affective experience remains insufficiently understood. This study proposes an affect-centered framework to examine how different virtual agent persona styles (Lis …

03.09.2026journal-article

Frontiers in Digital Health

Hardware-aware knowledge-distilled CNN for real-time classification of plaque-associated angiographic findings on FPGA

Nazarkar Pravalika, Jabeena Afthab, Vetriveeran Rajamani

Coronary artery disease (CAD) is one of the leading causes of global mortality, necessitating accurate assessment of coronary artery stenosis and plaque-associated angiographic findings from coronary angiography images. Although deep learning-based diagnostic models have demonstrated high predictive capability, their deployment on resource-constrained embedded platforms remains challenging because of computational complexity and memory requirements. To address these limitations, this study proposes a knowledge-dist …

03.09.2026journal-article

Frontiers in Public Health

The need for measurable targets in national action plans on antimicrobial resistance: opportunities for action

Uswa H. Shafaque, Arne Ruckert, Samuel Orubu, Kayla Strong, Suzanne Garkay Naro, Susan Rogers Van Katwyk, Mathieu J. P. Poirier

Antimicrobial resistance (AMR) represents a significant global health challenge that defies simple solutions and requires multisectoral coordination and interdisciplinary collaboration. National action plans (NAPs), which are built on the template of the World Health Organization’s Global Action Plan on AMR, offer a critical framework for addressing AMR. However, the lack of measurable targets within many NAPs hinders progress in mitigating AMR and setting up accountability and monitoring frameworks for tracking im …

03.09.2026journal-article

Frontiers in Oncology

The expression and clinical significance of SIRT5, H2A and TOP2A in cervical cancer

Fenghu Li, Xue Tian, Fan Mei, Yanjun Du, Lili Hu, Jiehui Li, Shengfa Su, Bing Lu

Objective To analyze the correlation between the expression of lysine deacetylase 5 (SIRT5), histone H2A and topoisomerase IIα (TOP2A) protein with clinical stage and survival in cervical cancer. Methods The expression levels of SIRT5, H2A and TOP2A proteins were detected by immunohistochemical two-step method in paraffin-embedded tissue blocks from 65 patients with cervical cancer (21 cases of stage IB, 9 cases of stage IIA and 35 cases of stage IIIC1p). The expression distribution and positive rate of SIRT5, H2A …

03.09.2026journal-article

Forensics analyst

Specifics of Forensic Support for Economic Crime Investigations Based on a Comprehensive Analysis of a Personal Digital Profile

Nina V. Olinder

The article examines current economic crime investigations in the context of the digital transformation of the economy and the record growth in damages from such acts. Based on a practical analysis, a conceptual approach to integrating a person’s digital profile into a forensic support system for crime investigations is developed. A framework for a comprehensive digital profile analysis is proposed, comprising three blocks: payment and identification, communication and network, and psychological and behavioral one. …

03.09.2026journal-article

Clinical Chemistry and Laboratory Medicine (CCLM)

Toward harmonized reporting of Alzheimer’s disease biomarkers in clinical practice

Luisa Agnello, Andrea Pilotto, Lorenzo Gaetani, Giovanni Bellomo, Valentina Bessi, Marco Bozzali, Annachiara Cagnin, Angelo Labate, Federico Massa, Fabio Moda, Roberto Monastero, Giulia Musso, Tommaso Piccoli, Giulia Sancesario, Lucilla Parnetti, Alessandro Padovani, Marcello Ciaccio

Abstract Cerebrospinal fluid biomarkers, and more recently blood-based biomarkers, are playing a pivotal role in reshaping the clinical management of neurodegenerative diseases, supporting early detection, biological diagnosis, patient stratification, prognostic assessment, therapeutic decision-making, and longitudinal disease monitoring. To effectively support clinical decision-making, biomarker measurements must be communicated in a standardized, transparent, and clinically interpretable manner. Despite internati …

03.09.2026journal-article

Clinical and Experimental Dermatology

Uncommon benign tumour of the scalp

Peter Robinson, Sam Cook, Stephanie Ball, Fraser Charlton, Neil Rajan

A 37-year-old male (Fitzpatrick skin type III) presented with a 10-month history of an enlarging nodule on the right parietal scalp. There was a paternal history of melanoma, but no family history of similar skin lesions. Physical examination revealed an ill-defined, pink, round, non-tender, mobile nodule measuring 15 x 15 mm. A second similar papule measuring 6 x 5 mm was found at the right scalp apex.

03.09.2026journal-article

Frontiers in Public Health

Understanding the needs of employees with non-communicable diseases regarding physical activity-related workplace health promotion programs: a qualitative study

Andrea Schaller, Lena Katharina Spanio, Martin Lange

Introduction The prevalence of non-communicable diseases (NCD) is rising and increasingly affects people of working age. Thereby, NCD burden those affected and challenge society, welfare systems and companies in many different ways. Workplace Health Promotion (WHP) is considered promising to improve and maintain employee health and physical activity (PA)-related WHP programs constitute a main area of action. This study aimed to better understand the needs employees with NCD have with regard to PA related WHP progra …

03.09.2026journal-article

Frontiers in Psychology

Psychometric properties of the test of nonverbal intelligence–third edition (TONI-3) in Turkish middle school students

Ahmet Bildiren, Sevinç Zeynep Kavruk

Background The aim of this study was to examine the psychometric properties of Form A of the Test of Nonverbal Intelligence–Third Edition (TONI-3) in Turkish middle school students aged 10 years 0 months to 14 years 0 months. Although TONI-3 has previously been validated in Turkish children and late adolescents, psychometric evidence for early adolescence remains limited. Method The sample consisted of 1,041 middle school students in Aydın province (50.6% female; M = 11.74, SD = 1.15), selected using stratified clu …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

A clinical prediction model for post-procedural hemolysis after transcatheter VSD closure in children

Jingyi Tian, Xinru Gan, Dan Yin, Huichao Sun, Ping Xiang, Mi Li

Background Transcatheter closure has been widely used for the treatment of ventricular septal defect (VSD) in children. However, post-procedural hemolysis remains a clinically relevant complication, and its underlying mechanisms and risk factors have not been systematically investigated. Methods In this single-center retrospective cohort study, children who underwent transcatheter VSD closure at the Children's Hospital of Chongqing Medical University between June 2015 and June 2024 were included. Perioperative clin …

03.09.2026journal-article

Frontiers in Artificial Intelligence

Words matter: measuring and titrating the communicative character of AI

William C. Kouns

As large language models become primary communication partners, the stylistic and communicative character of their output—specifically the degree to which it relies on intellectual, affective, or action-oriented language—shapes how users interpret, and act on what they read. Yet this property is rarely measured or controlled directly. We introduce the Intellect-Emotion-Action Profile (IEAP), a purpose-built lexical framework featuring an inductively constructed dictionary from AI-generated text. IEAP decomposes any …

03.09.2026journal-article

Ege Tıp Dergisi

Clinical correlates of follow-up discontinuation in adult psychiatric outpatients: A retrospective cohort study

Deniz Alçı, Sevda Yıldız Saray

Aim: This study aimed to compare treatment continuation and follow-up discontinuation in adult psychiatric outpatients and to evaluate the clinical variables associated with discontinuation.Materials and Methods: In this retrospective, single-center, observational study, patients aged 18 years and older who were evaluated and started on treatment at the Psychiatry Outpatient Clinic of Balıkesir University Faculty of Medicine Hospital between January 1, 2024 and December 31, 2024 were reviewed. One hundred patients …

03.09.2026journal-article

Frontiers in Public Health

Knowledge, perceptions, and support for human milk banking among Saudi mothers: a cross-sectional study

Yahya A. Almutawif, Renad M. Alhamawi

Background Donor Human Milk (DHM) is recommended for preterm infants when a mother’s own milk is unavailable. This study explored Saudi mothers’ knowledge, attitudes, and concerns regarding human milk banking (HMB) and donation, to identify barriers to acceptance and to inform future implementation. Methods A cross-sectional survey of 835 mothers across Saudi regions assessed support for HMB and its association with sociodemographic factors, feeding practices, breastfeeding duration, and knowledge of the benefits o …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Cardiac safety of L-Annamycin: a pooled analysis of five clinical trials

Ziad Zalaquett, Stuart Waymack, Patrick Collier

Background Anthracyclines are highly effective chemotherapeutic agents but are limited by cumulative, dose-dependent cardiotoxicity, leading to strict lifetime exposure thresholds. L-Annamycin is a next-generation liposomal anthracycline designed to preserve antitumor efficacy while reducing cardiotoxicity. Methods We performed a pooled analysis of cardiac safety data from five sponsor- and investigator-initiated clinical trials evaluating L-Annamycin in acute myelogenous leukemia (AML) and metastatic soft tissue s …