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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Therapie & Reha · Seite 176

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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
13.08.2026journal-article

PLOS One

Prevalence and determinants of soil transmitted helminth infections among children on Highly Active Antiretroviral Therapy (HAART) in Mulobezi and Sesheke Districts, Zambia: A cross – sectional study

Benjamin Mbonshi, Evans Mwape Kabemba, Collins Bowa

Background Soil-transmitted helminth (STH) infections are a major public health challenge in regions where they overlap with HIV/AIDS. Children with HIV may be especially vulnerable to STHs due to immunosuppression, yet the burden and drivers of this co-infection among those on antiretroviral therapy (ART) in Zambia are not well documented. This study aimed to determine the prevalence and identify the key determinants of STH infections among ART-treated children in Western (Mulobezi and Sesheke districts) Zambia. M …

13.08.2026journal-article

Indonesian Journal of Innovation Multidisipliner Research

Molecular Basis for the Adjuvant Potential of Nigella sativa–Derived Bioactive Constituents in Overcoming Resistance to Cancer Therapy

Nasywa Zahirah Yustin, Ghani Phalosa, Feby Anastasya Sirait

Resistance to cancer therapy remains a major cause of treatment failure, tumor recurrence, and disease progression because malignant cells can adapt through interconnected mechanisms involving prosurvival signaling, apoptosis suppression, drug efflux, epithelial–mesenchymal plasticity, cancer stemness, and the tumor microenvironment. This narrative review evaluates the molecular basis and adjuvant potential of Nigella sativa–derived bioactive constituents in overcoming resistance to conventional cancer therapies. R …

13.08.2026journal-article

BMC Health Services Research

Organizational determinants of psychological safety and occupational stress in healthcare: a phenomenological study in a tertiary health system

Ibrahim Alghamdi, Shadi Ashour

Abstract Background Modern healthcare ecosystems are shaped by rising service demands, structural workforce shortages, and heightened organizational complexity. While individual-level burnout has been widely evaluated, the underlying organizational determinants that systematically influence psychological safety and occupational stress require deeper investigation. This study explores how healthcare structures, leadership execution, and workload governance shape these dynamics within a transforming tertiary health s …

13.08.2026journal-article

Cell and Gene Therapy Insights

Reflecting on the evolution of gene therapy from good idea to mundane miracle

Paula Cannon

“Five years from now, when we have treated and cured many people with sickle cell disease, it will begin to feel mundane.” Abi Pinchbeck, Editor, Cell and Gene Therapy Insights, speaks with Paula Cannon, Distinguished Professor of Molecular Microbiology and Immunology, Keck School of Medicine of USC, about the evolution of gene therapy from a bold engineering challenge to an increasingly routine clinical reality. They discuss the financial and regulatory barriers to patient access, the field’s perceived image probl …

13.08.2026journal-article

Case Reports in Ophthalmology

Acute Orbital Inflammation Following Neridronate Therapy: A Case Report

Sofia Ginelli, Jennifer Cattaneo, Anna Bruno, Francesca Mojana, Simona Caprani, Stefano Ranno

Introduction Bisphosphonates are known to occasionally induce ocular and orbital inflammation. While most reported cases involve agents such as zoledronate or alendronate, reports associated with neridronate remain exceedingly rare. Early recognition is vital as this condition can be vision-threatening but typically responds well to treatment. Case Presentation We describe a 69-year-old man who developed fever and myalgia, followed by the abrupt onset of severe unilateral orbital inflammation 72 hours after receivi …

13.08.2026journal-article

Frontiers in Endocrinology

Central and peripheral areal BMD, bone microarchitecture, and strength after initiation of androgen deprivation therapy in men with prostate cancer: a two-year follow-up study

Marsha M. van Oostwaard, Melissa S.A.M. Bevers, Johanna H.M. Driessen, Caroline E. Wyers, Joop P. van den Bergh

Introduction Androgen Deprivation Therapy (ADT) in prostate cancer (PCa) is associated with bone loss and increased fracture risk. Previous studies on the effects of ADT on bone have focused on areal bone mineral density (aBMD) from dual-energy X-ray absorptiometry (DXA) at the central skeleton, while the effects on peripheral aBMD, bone microarchitecture, and bone strength are less well studied. Methods In this two-year observational study, we examined the changes in aBMD and volumetric BMD, bone area, microarchit …

13.08.2026journal-article

International Journal of Web of Multidisciplinary Studies

Healing effect of ultrasonic sound wave therapy in case of femoral osteochondritis disecans. A narrative review

Dr.Ashish Yadav, Dr.Sudhansu Bhusan Mangaraj

ABSTRACT Background: Osteochondritis dissecans is a condition in which a segment of articular cartilage with its underlying subchondral bone gradually separates from the surrounding bone. Aim: The study's objective is to assess the therapeutic benefits of conservative physiotherapy. In order to determine the persuasiveness of ultrasonic wave treatment's fundamental therapeutic effects, practice-based conservative physical therapy is ultimately required. This assessment demonstrates both the repair of cartilage and …

13.08.2026journal-article

Advanced Electromagnetics

Analysis on the Effect of Chinese Herbs Decoction Combined with Warm Acupuncture and Auricular Point Sticking Therapy on Insomnia Caused by Deficiency of Both Qi and Yin

L. Zhang, W. G. Xue, Y. Wang, H. X. Zhang, Y. Ma

Objective: This study investigates the therapeutic effect of Chinese herb decoction combined with warm acupuncture and auricular point sticking therapy on insomnia caused by deficiency of both Qi and Yin. Methods: A total of 104 patients with Qi-Yin deficiency-type insomnia admitted to the hospital from November 2023 to November 2024 are selected and randomly divided into Group A and Group B, with 52 cases in each group, using the random number table method. Group B receives routine Western medical treatment, while …

13.08.2026journal-article

Advanced Science

Kidney‐Targeted Cilastatin Nanoparticles Inhibit DPEP1‐Mediated Ferroptosis for Acute Kidney Injury Therapy

Wanbing Qin, Jiaqi Huang, Manting Zhang, Wanchun Yang, Mingwei Xu, Chi Jiang, Jiekai Li, Jinjuan Wen, Qibin Huang, Shiqi Wen, Weidong Wang, Junbing He, Qinghua Liu

ABSTRACT Cisplatin‐induced acute kidney injury (CI‐AKI) is a frequent, dose‐dependent complication in patients receiving cisplatin chemotherapy, and effective targeted treatments remain unavailable. The development of targeted therapies for CI‐AKI may improve the efficacy of chemotherapy while mitigating renal toxicity. Given that ferroptosis is a key pathological mechanism in CI‐AKI, targeted drug delivery systems against this process represent a promising therapeutic strategy. Dipeptidase 1 (DPEP1) is highly expr …

13.08.2026journal-article

Electronics

AS-Split Conformer: A Stage-Wise Convolution–Attention Framework with Mamba Decoder for End-to-End Speech Recognition

Lulu Qin, Xuan Fu, Mingchen Sun, Dadong Wang

Automatic speech recognition (ASR) systems based on Conformer architectures achieve strong performance by jointly modeling local acoustic patterns and global contextual dependencies. However, their interleaved convolution–attention design leads to progressive entanglement of fine-grained acoustic features and global semantic representations, which weakens monotonic alignment in speech recognition and degrades performance in long utterances. To address this limitation, we propose an AS-Split Conformer–Mamba framewor …

13.08.2026journal-article

Neurological Research and Practice

Guideline of the German Society of Neurology (DGN): "diagnosis and therapy of HIV-1-associated neurological disorders”

Katrin Hahn, Gabriele Arendt, Christian Eggers, Cristina Granziera, Matthias Maschke

Abstract Epidemiology and treatment of HIV changed substantially within the last three decades. However, HIV-associated neurological disorders such as mild forms of HIV-associated neurocognitive disorder (HAND) as well as HIV-associated distal symmetrical sensory polyneuropathy are amongst the most frequent complications in patients with longstanding HIV infection. Opportunistic infections occur less frequently compared to former years, but especially in patients with late presentation of HIV progressive multifocal …

13.08.2026journal-article

Frontiers in Neurology

Robot-assisted integrated cognitive-motor rehabilitation in patients with chronic stroke: a randomized controlled trial

Seungwoo Cha, Jiyeon Lee, Hyojin Jeon, Min Ho Chun

Background Cognitive and motor impairments are major determinants of functional independence after stroke. While robot-assisted training is effective for motor recovery, its impact on cognitive function through integrated cognitive–motor training remains less explored. This study evaluated the effects of an end-effector robot-assisted integrated cognitive–motor rehabilitation program on global cognitive function and upper limb motor outcomes in patients with chronic stroke. Methods In this single-center, randomized …

13.08.2026journal-article

LIFE: International Journal of Health and Life-Sciences

EFFECT OF RADIAL EXTRACORPOREAL SHOCK WAVE THERAPY ON MUSCLE POWER OUTPUT IN MAJOR THIGH MUSCLE GROUPS

Riki Tanaka, Kensei Tsujimoto, Tetsushi Moriguchi

Background: Radial extracorporeal shock wave therapy (rESWT) is widely used in sports medicine for pain relief and functional recovery; however, quantitative evidence regarding its immediate effects on neuromuscular performance in healthy athletes remains limited. Objective: To determine the acute effects of rESWT applied to the mid-quadriceps on isokinetic knee extension and flexion output in female university athletes. Methods: Eleven female university athletes (18–22 years) completed rESWT and control conditions …

13.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Feasibility and functional benefits of a workplace short-burst walking intervention: A pilot study in sedentary middle-aged employees

Ravi Shankar Reddy

Background Prolonged sedentary behavior among office workers is associated with reduced physical function, increased fatigue, and decreased occupational well-being. Short-burst walking interventions have shown promise in counteracting these risks but require further evidence regarding their feasibility and functional impact in workplace settings. Objective To evaluate the feasibility and preliminary efficacy of a short-burst walking intervention on functional mobility and self-reported work outcomes among sedentary …

13.08.2026journal-article

Stem Cells and Development

The Potential Role of Mesenchymal Stem Cell Therapy for Moderate-to-Severe Atopic Dermatitis: A Systematic Review and Meta-Analysis of Human Clinical Trials

Martin Cevallos-Cueva, Laura Ghanem, Taissa Novis, Sakshi Arora, Najwaa Kirmani, Sümeyye Aktaş, Esteban Fernández-Faith

Despite currently available treatment options for moderate-to-severe atopic dermatitis (AD), some patients fail to achieve adequate disease control. Emerging evidence suggests that mesenchymal stem cells (MSCs) may represent a promising therapeutic option. This systematic review and meta-analysis included four randomized controlled trials (RCTs) and one non-randomized clinical trial. Eligible studies evaluated patients with moderate-to-severe AD treated with MSCs derived from human umbilical cord blood, autologous …

13.08.2026journal-article

Evidence-Based Dentistry

Chemically modified curcumin in periodontal therapy: a scoping review

Vishala Bhargavi Chilukuri, Rupali Agnihotri, Deepa G. Kamath

Abstract Aims/Objectives Periodontitis, a multifactorial chronic inflammatory disease that destroys the supporting structures of the teeth, is conventionally managed with treatments focusing on biofilm removal; however, these therapies do not fully address the dysregulated host response central to disease progression. To address this, chemically modified curcumin (CMC) analogues have been developed by modifying curcumin, a derivative of Curcuma longa , a host-modulating agent with potent anti-inflammatory and antio …

1 Zitationen
13.08.2026journal-article

BMC Pulmonary Medicine

Age-related effects of comprehensive in-patient physiotherapy after lung cancer surgery across age groups: an ambispective observational cohort study in middle-aged and older patients

Ayse Sena Manzak Dursun, Betul Cinar, Fuat Gökdemir, Omer Soysal, Alis Kostanoğlu

Abstract Background Postoperative recovery after lung cancer surgery may be influenced by age, comorbidity burden, and perioperative rehabilitation strategies. However, evidence regarding the age-related effects of structured early inpatient physiotherapy programs remains limited. This study aimed to evaluate the age-related effects of a comprehensive in patient physiotherapy (CIPT) program on hospital length of stay (LoS), clinical parameters, symptom-related outcomes, and inflammatory biomarkers in patients under …

13.08.2026journal-article

Russian Journal of Cardiology

Efficacy of immunosuppressive therapy in the treatment of myocarditis and inflammatory cardiomyopathy. A systematic review

N. A. Varavin, E. M. Petrova, D. A. Volkova, I. A. Puzhalov, N. I. Gulyaev

Aim . To systematize published data evaluating the effectiveness of immunosuppressive therapy (IST) in the treatment of myocarditis and inflammatory cardiomyopathy. Material and methods. A systematic search was conducted for studies evaluating the effectiveness of IST in the treatment of myocarditis and inflammatory cardiomyopathy between 1995 and 2025. R e sults . Thirteen studies were included in the systematic review. Twelve studies found a positive effect of IST, including improved left ventricular (LV) ejectio …

13.08.2026journal-article

Small

Delivery of Mitoxantrone by Biodegradable Cobalt‐Doped Hollow Prussian Blue Nanoparticles for Synergetic Photothermal Amplified Chemodynamic Therapy/Chemotherapy/Metalloimmunotherapy Against Tumor

Liyou Guo, Nannan Fu, Yuanyuan Fu, Shan‐Shan Xue, Yuxing Xie, Shili Zhou, Jinyang Wang, Qiuhua Li, Ming Li, Gen He, Dong‐Yang Zhang

ABSTRACT Immunotherapy has revolutionized antitumor treatment, but its effectiveness is severely compromised by the immunosuppressive tumor microenvironment (TME) and inadequate induction of antitumor immune responses, with most solid tumors remaining immunologically “cold” and unresponsive to monotherapies. Mitoxantrone (MTO), a first‐line chemotherapeutic agent, is additionally limited by poor bioavailability, acquired drug resistance, and insufficient immune activation. Herein, we developed biodegradable cobalt‐ …

13.08.2026journal-article

Cancer Gene Therapy

Targeting HDAC and proteostasis to eradicate quiescent cancer cells

Qi Jiang, Michelle Ertel, Austin Arrigo, Amjad Hijazzi, Sara Sannino, Jennifer L. Goeckeler-Fried, April Sagan, Ian Beddows, Betsy Ann Varghese, Daniel D. Brown, Wayne Stallaert, Adrian Lee, Amanda M. Clark, Hui Shen, Jeffrey L. Brodsky, Hatice U. Osmanbeyoglu, Ronald J. Buckanovich

Abstract Chemotherapy remains the primary treatment for ovarian cancer (OvCa), and chemoresistance drives patient mortality. Cellular quiescence, reversible exit from the cell cycle, increases chemotherapy resistance as chemotherapies primarily target rapidly proliferating cells. Here, we report that CHD4 and MBD3, components of the nucleosome remodeling and deacetylase (NuRD) complex, are downregulated in quiescent OvCa cells (qOvCa). We find that either CHD4 or MBD3 knockdown or histone deacetylase inhibitors (HD …

13.08.2026journal-article

Rehabilitation Counseling Bulletin

Family-Led Intervention in Improving Employment Outcomes for Persons With Intellectual Disabilities: CBT and MI: A Pilot Study

Abdoulaye Diallo, Lidia Fonseca, Omobolanle Wunuken, Diana Holland

This pilot randomized controlled trial examined whether a brief, family-led cognitive behavioral therapy and motivational interviewing intervention improved employment motivation among adults with intellectual disabilities. Intellectual disability is characterized by limitations in intellectual functioning and adaptive behavior, originating before age 18; it involves challenges in conceptual, social, and practical skills that affect everyday functioning. Fifty-two adults with moderate intellectual disability were r …

13.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

How Patients Hospitalized for Chronic Obstructive Pulmonary Disease Exacerbation Understood Dyspnea Management in Acute Occupational Therapy

Yasunori Imaoka, Sho Maruyama, Syota Matsumoto, Keita Yuba, Osamu Hataji

This qualitative study explored how patients hospitalized for chronic obstructive pulmonary disease (COPD) exacerbation interpreted dyspnea-management strategies learned during acute occupational therapy (OT) and how they related those strategies to anticipated use after discharge. Semi-structured interviews were conducted before discharge with 15 patients, 14 of whom were male, who received acute OT at a single acute care hospital in Japan, and the data were analyzed using reflexive thematic analysis. Patients des …

13.08.2026journal-article

Turkish Journal of Medical Sciences

Association of occupational lead exposure with erythrocytic parameters and nitric oxide–related metabolites: a case-control study ​​

MELİH GAFFAR GÖZÜKARA, SERVET BİRGİN İRİTAŞ, DENİZ ÖZKAN VARDAR, LÜTFİYE TUTKUN, ÖZLEM İRİTAŞ, SERDAR DENİZ, VUGAR ALİ TÜRKSOY, ENGİN TUTKUN

Background/aim: Occupational lead (Pb) exposure remains a significant public health concern due to its persistent presence in industrial environments and its cumulative toxic effects. Although the hematological and neurological consequences of Pb exposure are well documented, early vascular effects and the mechanisms associated with potential endothelial impairment remain unclear. This study aimed to investigate the associations between Pb exposure, erythrocytic parameters, and nitric oxide (NO)–related metabolites …