Therapie & Reha: neue Gesundheitspublikationen – Seite 171

14.08.2026journal-article

REVISTA DE ESTUDOS INTERDISCIPLINARES

VIVÊNCIAS ACADÊMICAS E QUALIDADE DE VIDA NO ENSINO SUPERIOR

Beatriz Freitas Launé, Cleiziane Lima de Oliveira, Elson Ferreira Costa Costa, Lucivaldo da Silva Araújo, Debóra Ribeiro da Silva Campos Folha

O estudo analisou a relação entre vivências acadêmicas e qualidade de vida de estudantes do curso de Terapia Ocupacional da Universidade do Estado do Pará. A pesquisa permite a compreensão de que o ingresso e permanência no ensino superior exige adaptações significativas e pode impactar tanto o desempenho acadêmico quanto o bem-estar dos discentes. O objetivo central buscou analisar as vivências acadêmicas e as percepções sobre a qualidade de vida de estudantes de Terapia Ocupacional, considerando aspectos sociodem …

14.08.2026journal-article

BDJ Open

Impact of post-resection maxillofacial defects on outcomes of 3D-printed prosthetic rehabilitation in oral cancer patients: a scoping review protocol

Smitha Sammith Shetty, Shibani Shetty, Sameep S. Shetty, Swapna BV

Abstract Introduction Oral cancer patients undergoing surgical resection often develop extensive maxillofacial defects that compromise function, aesthetics, and quality of life. Three-dimensional (3D) printing has enabled the development of customized, patient-specific prostheses, offering improved precision in rehabilitation. However, the extent to which defect type and location influence prosthetic outcomes remains inadequately synthesized in the current literature. Objective To map and synthesize the available e …

14.08.2026journal-article

Gynecology and Minimally Invasive Therapy

Resection of Ovarian Teratoma for the Treatment of Anti-N-Methyl-D-aspartate Receptor Encephalitis – The New Battey’s Operation: A Case Report

Poh Ting Lim, Siak Ming Goh, Satish Kumar Reddy Challa, Simon Robert Ling

Abstract We present the case of a 14-year-old girl diagnosed with Anti-N-Methyl-D-aspartate Receptor (NMDAR) encephalitis following the onset of acute seizures associated with dysautonomia and hallucinations, successfully treated after a laparoscopic ovarian cystectomy and immunotherapy. Histology of the ovarian cyst confirmed the diagnosis of an ovarian teratoma with neural tissues. She then underwent neurorehabilitation and had full recovery of her neurological and functional status. This case highlights the impo …

14.08.2026journal-article

International Journal of Law and Society

Juridical Analysis of Criminal Punishment and Rehabilitation for Narcotics Offenders in Islamic Criminal Law.

Resi Darwis, A. Husin Ritonga, Hermanto Harun, Abdul Halim

This study aims to analyze the criminalization provisions for narcotic abuse under Indonesian positive law, examine the concept of rehabilitation for narcotic abusers within the Indonesian legal system, and investigate the Islamic criminal law perspective on the criminalization and rehabilitation of narcotic abusers. This research employs a normative-juridical approach using qualitative methods through library research. Data were collected from primary sources including the Qur'an, Hadith, and narcotic-related legi …

14.08.2026journal-article

Journal of Monolingual and Bilingual Speech

Referent Mention When Parents Tell a Story: A Means to Explain Children's Referential Uses in Narratives

Camille Dupret

Abstract This study aims to describe parents’ referential choices while recounting a story to their child. Indeed, in choosing referring expressions (REs), until the 8 years of age or even later, children are less sensitive to discourse accessibility than factors such as visual accessibility or characters’ status within the story. In this study, 24 parents’ narratives co-constructed with their child (mean age: 6;06) from a textless picture book were video-recorded. REs were coded according to their form (pronouns, …

14.08.2026journal-article

Turkish Journal of Biology

Profiling arbutin as a potent cholinesterase and GSK-3β inhibitor and evaluating its cytotoxicity in SH-SY5Y cells for Alzheimer’s disease therapy

SHIRIN TARBIAT, TUĞBA BAL, DENİZ GÜLMEZ

Background/aim: Alzheimer’s disease (AD) is a neurodegenerative disorder linked to cognitive decline and memory loss, marked by hyperphosphorylated tau tangles and decreased acetylcholine levels, which are affected by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity. Glycogen synthase kinase-3 beta (GSK-3β) also plays a role in AD through abnormal activation. In this study, the potential of β-arbutin to inhibit cholinesterases and GSK-3β was investigated, utilizing in vitro assays, cytotoxicit …

14.08.2026journal-article

Monoclonal Antibodies in Immunodiagnosis & Immunotherapy

Monoclonal Antibody-Based Anti-Cryptococcosis Therapy

Marcos William de Lima Gualque, Gabriel Rezende Pimenta, Daniel Gomes de Sousa, Lara Yukari Ogasawara, Aline Ruan Wu, Mariana Macul, Matheus Torrichelli Antunes, Marcela Santana Demarchi, Giovana Moreno Fratus, Maria Júlia Siqueto, Andrei Moroz, Maria José Soares Mendes Giannini, Ana Marisa Fusco Almeida

Cryptococcosis remains one of the most severe invasive fungal diseases worldwide, causing high morbidity and mortality, particularly among immunocompromised individuals. Despite the availability of antifungal drugs, current therapeutic regimens are limited by drug toxicity, prolonged treatment, antifungal resistance, biofilm-associated tolerance, and frequent disease relapse, highlighting the need for novel therapeutic approaches. Monoclonal antibodies (mAbs) have emerged as promising immunotherapeutic agents becau …

14.08.2026journal-article

International Journal of Innovative Technologies in Social Science

ISOTRETINOIN THERAPY AND ITS IMPACT ON DEPRESSION: A COMPREHENSIVE LITERATURE REVIEW

Filip Kamyszek, Marta Krężołek, Julia Dobrowolska, Alicja Palus, Kornel Pawlak, Marcin Stępiński, Mateusz Balicki, Oliwia Zynek, Paula Kaczmarczyk, Tomasz Arkuszyński

Background: The association between isotretinoin therapy and depression remains controversial. Early case reports suggested a potential link with psychiatric adverse effects, whereas contemporary large-scale studies have produced conflicting results. Methods: A structured literature review was conducted using PubMed/MEDLINE, Cochrane Library, and Google Scholar. Studies included systematic reviews, meta-analyses, cohort studies, and mechanistic research published between 2000 and 2024. Results: Most high-quality st …

14.08.2026journal-article

Mindfulness

Acceptability and Feasibility of Mindfulness-Based Cognitive Therapy in Adults with Inflammatory Bowel Disease: A Mixed-Methods Study

Milou M Ter Avest, Loes HC Nissen, Sabien JE Bosman, Ilse Dijkman, Anne EM Speckens, Marloes J Huijbers

Abstract Objectives The high psychological burden of inflammatory bowel diseases (IBD) underscores the need for effective and feasible psychological treatment options. This study aimed to explore the acceptability and feasibility of mindfulness-based cognitive therapy (MBCT) for adults with IBD. Method This mixed-methods study was embedded in a multicenter randomized controlled trial on the effectiveness of MBCT in IBD. Reasons for participation were discussed in the context of the trial and reasons for non-partici …

14.08.2026journal-article

eneuro

Auditory Brainstem Encoding of Speech-in-Noise Predicts Word Identification, Narrative Comprehension, and Subjective Listening Effort in a Selective Attention Task

Kelsey Mankel, Daniel C. Comstock, Brett M. Bormann, Soukhin Das, Doron Sagiv, Hilary Brodie, Lee M. Miller

The auditory brainstem plays a crucial role in speech-in-noise (SiN) listening, refining numerous acoustic features such as pitch and spatial location under continual descending influence from the cortex. However, the difficulty of characterizing brainstem activity during continuous speech listening has obscured its functional role in ecologically valid contexts—not only the effects of selective attention on neural responses but also their impact on comprehension and listening effort. Here, we evaluated the role of …

14.08.2026journal-article

NEW SOLUTIONS: A Journal of Environmental and Occupational Health Policy

Translation and Validation of the Job Factor Questionnaire (JFQ) and Quick Exposure Check (QEC) into Malay Language for Small and Medium Food Manufacturing Industries (SME)

Melor Amran, Dayana Hazwani Mohd Suadi Nata, Ismarulyusda Ishak, Putri Anis Syahira Mohamad Jamil

Reliable assessment of ergonomic and job-related risk factors requires tools that are linguistically, culturally, and contextually appropriate. This study translated, culturally adapted, and preliminarily evaluated Malay versions of the Job Factor Questionnaire (JFQ) and Quick Exposure Check (QEC) among workers in Malaysian food manufacturing small- and medium-sized enterprises. The process included forward and backward translation, expert review, face validation, pilot testing, and psychometric evaluation. The ins …

14.08.2026journal-article

European Journal of Case Reports in Internal Medicine

Splenic artery embolization, a therapy that can be life-saving for small bowel variceal bleeding

Rached Radwan, Marianne Ghantous, Johny Salem, Joe Khoury, Antoine Geagea, Khalil Chidiac

Introduction: Small bowel varices are a rare manifestation of portal hypertension, accounting for only 1–5% of variceal gastrointestinal bleeding. Their diagnosis and management remain challenging because of their uncommon occurrence, difficult anatomical accessibility, and lack of standardized treatment strategies. We report a case of refractory small bowel variceal bleeding successfully treated with splenic artery embolization after failure of conventional therapeutic options. Case presentation: A 45-year-old man …

14.08.2026journal-article

Annals of the American Thoracic Society

Digital Exposure Therapy to Reduce Posttraumatic Stress Disorder Symptoms After Critical Illness: A Pilot Feasibility Study

Nadia Liyanage-Don, Karin Maria Nylocks, Sheila Rauch, Barbara Rothbaum, George E Sayde, Robin Cumella, Nakesha Fray, Talea Cornelius, Miguel Mendieta, Sheau-Yan Ho, Carla M Sevin, Ian M Kronish

Abstract Background Posttraumatic stress disorder (PTSD) is common after critical illness. Therapist-delivered exposure therapy is a first-line treatment, but often inaccessible due to cost, limited therapist availability, and perceived stigma. Mobile app-delivered exposure therapy may help address these barriers. Messy Memories is a novel smartphone app that guides patients through core exposure therapy techniques, including self-directed processing of prior distressing experiences. We evaluated the feasibility, a …

14.08.2026journal-article

Annals of Plastic Surgery

The Use of Negative Pressure Wound Therapy as an Adjunct Treatment in Patients Undergoing Sternal Wound Reconstruction With Pectoralis Major Flaps

Kevin Kuonqui, Michael B. Amrami, Dylan K. Kim, Myles N. LaValley, Julia K. Kim, Sarah Diaddigo, Jeffrey A. Ascherman

Background: Deep sternal wound infection and dehiscence following median sternotomy remain challenging clinical problems with high morbidity. Negative pressure wound therapy (NPWT) has been reported to improve wound healing outcomes in various types of wounds. However, the reported efficacy of NPWT in sternal wound reconstruction varies widely in the literature. There are few large-scale single-institution studies examining the preoperative factors associated with NPWT and associated postoperative outcomes. Methods …

14.08.2026journal-article

Journal of Fungi

Clinical and Economic Trade-Offs in Antifungal Therapy for Invasive Aspergillosis and Mucormycosis: A Markov Model–Based Analysis

Alejandro Rico Mendoza, Alexandra Porras Ramirez, Liliana Encinales, Oscar Madiedo, Marianna Carrillo Encinales, Juan Pablo Duque Bolivar, Juan Fernando Ramon Cuellar, Jorge Andrés Urquijo Mendez, Zuly Moreno Perilla, Roberto Jurado Zambrano

Invasive aspergillosis and mucormycosis are life-threatening fungal infections characterized by high early mortality, substantial toxicity, and intensive healthcare resource utilization. While multiple antifungal therapies are recommended in international guidelines, their comparative clinical and economic value remains uncertain, particularly in resource-limited settings. We developed a hybrid decision tree and Markov model to evaluate antifungal strategies, including liposomal amphotericin B, isavuconazole, voric …

14.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Identification of exposed body segments and risk levels in specialized construction tasks involving upper limbs above shoulder level

Mario Alberto Villegas Romero, Juan Luis Hernández Arellano, Jorge Hernán Restrepo Correa, Aidé Aracely Maldonado Macías

Background Musculoskeletal disorders are common among specialized construction workers due to repetitive, physically demanding work. However, biomechanical risks and the specific involvement of body segments in vaulted roof construction remain insufficiently characterized. Objective Identify the most exposed body segments and measure biomechanical risk in vaulted roof construction. Methods This observational study took place at six construction sites. Thirteen workers participated: six vault masters and seven helpe …

14.08.2026journal-article

Advances in Translational Research

Pharmacological strategies for relapsed multiple myeloma after T-cell engager therapy: From molecular mechanisms to translational opportunities

Hermina Sánta, Gergely Varga, Gábor Mikala

Abstract The treatment landscape of relapsed/refractory multiple myeloma (RRMM) has evolved significantly with the introduction of T-cell–redirecting therapies, including bispecific antibodies and chimeric antigen receptor (CAR) T-cell therapies. Despite high response rates observed with these approaches, disease progression remains inevitable for most patients, and no standard of care has been established for those relapsing after T-cell engager (TCE) therapies. Mechanisms of resistance include antigen loss, T-cel …

14.08.2026journal-article

Science and Innovation

PSYCHOMOTOR THERAPY COMBINED WITH COGNITIVE-BEHAVIORAL TECHNIQUES FOR NEUROTIC SYMPTOMS IN VASCULAR DEMENTIA: A PROSPECTIVE COMPARATIVE PILOT STUDY

S Karakhonova

Neuropsychiatric symptoms are common in vascular cognitive impairment and can complicate rehabilitation and long-term care. This 30-day prospective comparative pilot study evaluated two multimodal regimens for neurotic symptoms in patients with mild-to-moderate vascular dementia. Forty-six patients were enrolled, and 42 had complete baseline and end-of-treatment records for comparative analysis: 20 received basic neuroprotective therapy, rational psychotherapy, and temgicoluril (Adaptol), whereas 22 received basic …

14.08.2026journal-article

Journal of Marital and Family Therapy

Empirically Supported Couple Therapy Models for Couple Relationship Distress: A Replication and Update

Jeffrey B. Jackson, Luca Codecá, Richard B. Miller, Jessica E. Simpson, Abigail M. O'Leary, Samantha M. Renner

ABSTRACT This systematic review replicated and updated Baucom and colleagues' (1998) evaluation of empirically supported treatments (ESTs) for couple relationship distress using the Chambless criteria, the primary framework used by the American Psychological Association to classify ESTs. Applying these criteria to 40 eligible studies, we found that, in contrast to Baucom and colleagues, no couple therapy models met the standards for strong empirical support; insufficient sample size and lack of independent replicat …

14.08.2026journal-article

Journal of Medical Internet Research

AI-Powered Robotics Are Personalizing Rehabilitation

Benedette Cuffari

Abstract Rehabilitation is crucial for making a full recovery from surgery or managing a chronic physical disability, but it can be resource-intensive and highly individual in treatment response. In this News and Perspectives article, JMIR Correspondent Benedette Cuffari reports on robotics in rehabilitation and how AI is helping to make it more personalized, efficient, and effective.

14.08.2026journal-article

Current Oncology

Impact of Lebanon’s Economic Crisis on Cancer Care Delivery: A Multicenter Cross-Sectional Study of Treatment Initiation Delays and Incomplete Therapy

Mohamad Ali Hachem, Nadeen Zayour, Elie Daibess, Jacqueline Najjar, Elie Jean Karam, Solay Farhat, Zeinab Hammoud, Ghadir M. Nasreddine, Mohamad Abbass, Zeinab Sleiman, Maroun Sadek, Ahmad Ibrahim, Issam Chehade, Bassam Matar

Background/Objectives: In Lebanon, the economic crisis since 2019 has severely strained healthcare infrastructure, yet its impact on cancer treatment adherence remains incompletely characterized. This study assessed factors associated with treatment delay and regimen modification to identify barriers to optimal cancer care among Lebanese patients. Methods: This multicenter, cross-sectional study was conducted in five tertiary hospitals in Beirut, Lebanon, between 13 June 2024, and 27 June 2025. Demographic, clinica …

14.08.2026journal-article

Nutrients

Beyond Weight Loss: Skeletal Muscle Health During Incretin-Based Therapy in Patients with Diabesity

Edoardo Luigi Maria Mollero, Ivan Dozzani, Emilia Biamonte, Giulia Bendotti, Paolo Marzullo, Gianluca Aimaretti, Marco Gallo

Background: Incretin-based therapies (IBTs), including glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 receptor agonists (GIP/GLP-1 RAs), have transformed the management of obesity and type 2 diabetes mellitus (T2DM). Although these agents provide substantial metabolic and cardiometabolic benefits, their effects on skeletal muscle, particularly in older adults at increased risk of sarcopenia and functional decline, remain incomplete …

14.08.2026journal-article

Frontiers in Medicine

Therapy-related acute myeloid leukemia with 24-month latency after CD19 CAR-T cell therapy in relapsed/refractory diffuse large B-cell lymphoma: a case report

Manqi Su, Chentong Huang, Zhanna Zhang, Xiaoxia Wang, Panruo Jiang, Yiran Chen, Gongqiang Wu

Background Therapy-related myeloid neoplasms (t-MNs) have emerged as a serious late complication of CD19-directed chimeric antigen receptor (CAR) T-cell therapy. While large-scale studies have characterized the epidemiology of t-MNs, the mechanisms underlying their development remain incompletely understood, and cases with extended latency are rarely documented. We report a case of therapy-related acute myeloid leukemia (t-AML) occurring 24 months after initial CD19 CAR-T cell therapy, with longitudinal genomic mon …

14.08.2026journal-article

Transcultural Psychiatry

Navigating Faith-based Practices in Therapy: Psychotherapists’ Experiences in India

Ananda Krishnan, Amrita Deb

Addressing clients’ faith-based practices (FBPs) is indispensable in psychotherapy, especially in a religiously diverse country like India. This can be particularly challenging in contexts where psychotherapy is highly stigmatized and FBPs are culturally accepted. A review of the literature highlighted a gap in research on how psychotherapists negotiate FBPs in the Indian context. This pilot qualitative study aims to address this gap by exploring the experiences of Indian psychotherapists in navigating FBPs as ment …

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VIVÊNCIAS ACADÊMICAS E QUALIDADE DE VIDA NO ENSINO SUPERIOR

Impact of post-resection maxillofacial defects on outcomes of 3D-printed prosthetic rehabilitation in oral cancer patients: a scoping review protocol

Resection of Ovarian Teratoma for the Treatment of Anti-N-Methyl-D-aspartate Receptor Encephalitis – The New Battey’s Operation: A Case Report

Juridical Analysis of Criminal Punishment and Rehabilitation for Narcotics Offenders in Islamic Criminal Law.

Referent Mention When Parents Tell a Story: A Means to Explain Children's Referential Uses in Narratives

Profiling arbutin as a potent cholinesterase and GSK-3β inhibitor and evaluating its cytotoxicity in SH-SY5Y cells for Alzheimer’s disease therapy

Monoclonal Antibody-Based Anti-Cryptococcosis Therapy

ISOTRETINOIN THERAPY AND ITS IMPACT ON DEPRESSION: A COMPREHENSIVE LITERATURE REVIEW

Acceptability and Feasibility of Mindfulness-Based Cognitive Therapy in Adults with Inflammatory Bowel Disease: A Mixed-Methods Study

Auditory Brainstem Encoding of Speech-in-Noise Predicts Word Identification, Narrative Comprehension, and Subjective Listening Effort in a Selective Attention Task

Translation and Validation of the Job Factor Questionnaire (JFQ) and Quick Exposure Check (QEC) into Malay Language for Small and Medium Food Manufacturing Industries (SME)

Splenic artery embolization, a therapy that can be life-saving for small bowel variceal bleeding

Digital Exposure Therapy to Reduce Posttraumatic Stress Disorder Symptoms After Critical Illness: A Pilot Feasibility Study

The Use of Negative Pressure Wound Therapy as an Adjunct Treatment in Patients Undergoing Sternal Wound Reconstruction With Pectoralis Major Flaps

Clinical and Economic Trade-Offs in Antifungal Therapy for Invasive Aspergillosis and Mucormycosis: A Markov Model–Based Analysis

Identification of exposed body segments and risk levels in specialized construction tasks involving upper limbs above shoulder level

Pharmacological strategies for relapsed multiple myeloma after T-cell engager therapy: From molecular mechanisms to translational opportunities

PSYCHOMOTOR THERAPY COMBINED WITH COGNITIVE-BEHAVIORAL TECHNIQUES FOR NEUROTIC SYMPTOMS IN VASCULAR DEMENTIA: A PROSPECTIVE COMPARATIVE PILOT STUDY

Empirically Supported Couple Therapy Models for Couple Relationship Distress: A Replication and Update

AI-Powered Robotics Are Personalizing Rehabilitation

Impact of Lebanon’s Economic Crisis on Cancer Care Delivery: A Multicenter Cross-Sectional Study of Treatment Initiation Delays and Incomplete Therapy

Beyond Weight Loss: Skeletal Muscle Health During Incretin-Based Therapy in Patients with Diabesity

Therapy-related acute myeloid leukemia with 24-month latency after CD19 CAR-T cell therapy in relapsed/refractory diffuse large B-cell lymphoma: a case report

Navigating Faith-based Practices in Therapy: Psychotherapists’ Experiences in India