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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

Cardiology in Review

Supersaturated Oxygen Therapy for Wound Healing

Saumya Tawakley, Malathi Kalluri, Uttam Kalluri, William H. Frishman

Abstract: Chronic wounds are a major source of patient morbidity and healthcare expenditure, with impaired tissue oxygenation recognized as a notable obstacle to successful repair. Supersaturated oxygen (SSO 2 ) therapies have gained increasing traction as adjunctive treatments to improve the local wound environment and support the healing process. This review examines the current research and applications of SSO 2 therapy in wound healing, including its proposed biological effects, methods of administration, clini …

01.09.2026journal-article

Sanatorium Medical Journal

Temporary Penrose Catheter Fecal Diversion Combined with Negative-Pressure Wound Therapy in Extensive Fournier's Gangrene: A Simple Bridge Before Definitive Stoma Formation.

Ali Levent Işık, Ali Bekraki

Background: Fournier’s gangrene (FG) is a rapidly progressive polymicrobial necrotizing fasciitis of the perineal, perianal, and genital regions associated with high mortality rates. While aggressive surgical debridement and broad-spectrum antibiotics are the cornerstones of treatment, managing severe perianal wounds with extensive abdominal or retroperitoneal spread presents a significant therapeutic challenge. Fecal diversion is often required to prevent wound contamination, but definitive stoma formation can inc …

01.09.2026journal-article

Lecture Notes in Education Psychology and Public Media

Mechanisms and Intervention Pathways of School-Based Music Therapy for Alleviating Students' Academic Anxiety

Anhui Li

Against the backdrop of intensifying academic competition and rising learning pressure, academic anxiety has become highly prevalent among student populations. Conventional school-based psychological interventions are constrained by insufficient professional resources and high levels of student resistance. As a flexible, accessible, and non-pharmacological intervention, music therapy has been increasingly integrated into school mental health services. Employing a combination of literature review, case analysis, and …

01.09.2026journal-article

International Journal of Cancer

Developing Personalized Postoperative Follow‐Up Strategies for Patients With Locally Advanced Gastric Cancer Receiving Neoadjuvant Therapy Based on Dynamic Programming: A Multicenter Retrospective Cohort Study in China

Tianhao Li, Zheng Yang, Chenyu Liu, Lei Lian, Jianxian Lin, Peng Zhang, Hua Xiao, Xinxin Wang, Zhaoqing Tang, Wei Li, Kai Tao, Weiwei Sheng, Yi Cao, Linjun Wang, Jing Sun, Zizhen Zhang, Zheng Shi, Jie Yin, Zhen Wang, Shougen Cao, Shuqiang Yuan, Xinlu Liu, Liang Shang, Yuzhou Zhao, Kaixiong Tao

ABSTRACT The optimal follow‐up strategy for patients with locally advanced gastric cancer (LAGC) receiving neoadjuvant therapy (NAT) remains unknown. Traditional follow‐up strategies based on relatively fixed intervals fail to fully account for dynamic changes in recurrence risk. This study aimed to develop a personalized postoperative follow‐up strategy using dynamic programming (DP) to optimize follow‐up arrangements based on individual patient characteristics and dynamic recurrence risks. This study included 339 …

01.09.2026journal-article

F1000Research

Mapping Physical Therapy Goals to SMART and F-words Frameworks: Insights from Pediatric Neuromotor Rehabilitation in Qatar

Joel Anison, Eugene A. A. Rameckers, Gillian Ferguson

Background Goal setting is central to pediatric physical therapy and guides therapeutic planning and outcomes. For children with neuromotor disabilities, goals must be both technically sound and meaningful. The SMART framework (Specific, Measurable, Achievable, Relevant, and Time-bound) enhances clarity, while the F-words framework (Function, Family, Fitness, Fun, Friends, Future) emphasizes family-centered priorities. Evidence on goal analysis of children with neuromotor disabilities from Qatar remains limited. Ob …

03.09.2026journal-article

BMJ Open

Is home-based management feasible for COVID-19 patients requiring oxygen therapy? A participatory action study and cost analysis

Josi A Boeijen, Alma C van de Pol, Karin Smit, Rick T van Uum, Abeer Ahmad, Miriam P van der Meulen, Robert van den Broek, Wilma G Bijsterbosch, Roderick Venekamp, Frans H Rutten, Dorien LM Zwart

Objectives To explore feasibility and estimate cost of a home-based intervention for COVID-19 patients requiring oxygen therapy. Design and setting Participatory action study embedded in a regional collaborative healthcare network. Participants 13 patients were included (77% female; mean age 68 years, SD 18.2). Intervention A previously designed intervention was piloted and iteratively evaluated in a multidisciplinary expert panel using a participatory action research approach. Primary and secondary outcome measure …

03.09.2026journal-article

Cancer Medicine

Association of Ferritin Levels With Cytokine Release Syndrome in CAR T‐Cell Therapy: A Systematic Review and Meta‐Analysis

Ranjit Sah, Abhinav Bhattarai, Sangam Shah, Rachana Mehta, Sanjit Sah, Zeeshan Solangi, George P. Sorescu

ABSTRACT Background Ferritin elevation is frequently observed during cytokine release syndrome (CRS) following CAR T‐cell therapy; however, its independent clinical utility as a predictive or prognostic biomarker remains uncertain. We performed a systematic review critically evaluating the timing‐specific and context‐dependent role of ferritin in CRS risk stratification and outcomes. Methods We systematically searched PubMed, Web of Science, and Scopus for studies evaluating ferritin in CAR T‐cell recipients. We pe …

03.09.2026journal-article

Health Services Insights

Implementation Considerations for an Occupational Therapy-Led Mental Health Care Navigation Program for Older Adult Patients

Marina Motsenok, Shaghayegh Mirbaha, Mary Clarke, Kristin Morrow, Amanda Knoepfli, Naomi Ziegler, Tracey DasGupta, Sander L. Hitzig

Background Older adults with mental health (MH) challenges often face significant barriers when navigating complex healthcare systems, especially during critical transitions, such as hospital discharge. These challenges are compounded by comorbid physical illnesses, cognitive impairments, and social determinants of health. Objectives This qualitative study aimed to gain insights from patients and providers on factors influencing the implementation of an innovative occupational therapy (OT) led Patient Navigation Pr …

01.09.2026journal-article

Frontiers in Immunology

Neutrophil-associated extracellular DNA pathways in vitiligo: compartment-specific changes following combined fractional CO2 laser and NB-UVB therapy

Joanna Czerwińska, Alicja Frączek, Agnieszka Owczarczyk-Saczonek

Background Vitiligo is a chronic inflammatory depigmenting skin disorder characterized by progressive loss of functional melanocytes, in which adaptive immune mechanisms, particularly T-cell-mediated responses, play a well-established role. Emerging evidence suggests that innate immune pathways, including neutrophil activation, oxidative stress, and dysregulation of neutrophil extracellular trap (NET)-associated processes, may also contribute to disease-associated inflammation. Methods This study investigated NET-a …

01.09.2026journal-article

Journal of Medical Imaging and Radiation Oncology

Stereotactic Ablative Body Radiation Therapy for Spinal Oligometastases: Experience at a Single New Zealand Institution

Kathryn Tucker, Komeela Naidoo, Nur Azri Bin Mohd Yasin, John Chin, Charles De Groot, Roger Huang

ABSTRACT Purpose Spinal metastases are a common complication of advanced malignancy and can result in significant pain, neurological dysfunction, and reduced quality of life. In patients with oligometastatic disease, stereotactic ablative body radiation therapy (SABR) offers the potential for durable local control. This study reports outcomes following spinal SABR at Waikato Hospital and compares these with published literature. Methods A retrospective single‐centre cohort study was conducted of patients with oligo …

01.09.2026journal-article

Journal of Associated Medical Sciences

development of a conceptual model of occupational patterns promoting alcohol abstinence among northeastern Thais with alcohol use disorder

Rapeepat Boonphirom, Atsuko Tanimura, Supaluck Phadsri

Background: The difficulty of alcohol abstinence and recovery from unhealthy living patterns is influenced by individual context. There is still limited evidence to reveal concepts and processes of sustained alcohol abstinence in people with experienced alcohol use disorder, including Northeastern Thais. Objectives: This study aimed to develop a conceptual model explaining how Thais with alcohol use disorder in the northeastern region sustain their alcohol abstinence. Materials and methods: Charmaz’s constructivist …

01.09.2026journal-article

Journal of Korean Medicine

Changes in Facial Asymmetry following Chuna Manual Therapy-Centered Korean Medicine Treatment: A Retrospective Case Series of Four Patients

Eunho Jeong, Hoyeong Seong, Hyun-Jong Jung

Objectives: This study aimed to describe the treatment course and observed changes in patients with facial asymmetry who received Chuna Manual Therapy (CMT)-centered Korean Medicine (KM) treatment.Methods: This retrospective case series analyzed clinical records of four patients treated between January 2024 and April 2026. Eligible patients had no history of acute facial trauma or surgery, received no concurrent treatment for facial asymmetry, completed treatment, had complete pre- and post-treatment data, and prov …

01.09.2026journal-article

Advances in Humanities Research

The explanatory value of multidimensional measures of linguistic complexity for aphasia severity: evidence from AphasiaBank speech data

Lvxin Wang

Aphasia is an acquired language disorder marked by substantial individual variability. Quantitative measures of connected speech may clarify how linguistic performance relates to aphasia severity. Semi-spontaneous speech samples from 22 English-speaking adults with aphasia in the APROCSA subcorpus of AphasiaBank were analyzed. Eight measures represented three domains: Mean Length of Utterance (MLU), clause density, and embedded clause ratio for syntax; type–token ratio, verb diversity, and content-word ratio for le …

01.09.2026journal-article

Attahadi Medical Journal

Mathematical Modeling, Bio-Dynamic Analysis, and Optimal Control of Periodontal Disease Progression Incorporating Time Delays, Host-Modulation Therapy, and Realistic Clinical Scenarios

Emad Awadh

Periodontitis is a chronic multi-factorial inflammatory condition characterized by subgingival dysbiosis and immunopathological tissue breakdown, ultimately leading to connective-tissue attachment loss and alveolar bone resorption. This paper extends a previously formulated four-dimensional ordinary differential equation (ODE) model of subgingival bacterial biofilm, neutrophil/cytokine dynamics, tissue damage, and local antimicrobial pharmacokinetics into a five-dimensional delay-differential-equation (DDE) framewo …

01.09.2026journal-article

International Journal of Public Health Science (IJPHS)

Occupational skin diseases: a cross-sectional survey analysis

Ineke Winda Ferianasari, Reza Yuridian Purwoko, Evy Aryanti, Azizah Boenjamin, Silvan Saputra, Asmail Asmail

Occupational skin diseases (OSDs) are among the most common occupational diseases worldwide, yet scientific data in Indonesia remain limited. This issue is important to study because workers across various sectors frequently encounter wet work, detergents, and chemical exposure. The present study aimed to assess individual and occupational risk factors associated with skin complaints/symptoms on the hands and forearms within the past 12 months and to test the feasibility of a simple prediction model in the Indonesi …

01.09.2026journal-article

Frontiers in Digital Health

Time to first and recurrent missed video directly observed therapy sessions and associated factors among people with Tuberculosis in Kampala, Uganda

Kelvin Bwambale, Drake Amutuheire, Damalie Nakkonde, Patrick Kaggwa, Esther Buregyeya, Sarah Zalwango, Sarah Nabukeera, John B. Isunju, Juliet N. Sekandi

Background Video Directly Observed Therapy (VDOT) provides a promising alternative to in-person directly observed therapy (DOT) for Tuberculosis (TB) treatment adherence monitoring. However, sustained patient engagement and missed video submissions remain a challenge. This study examined the time to first and recurrent missed VDOT submissions and the associated factors. Methods We conducted a retrospective cohort analysis study of 71 people with TB assigned to the VDOT arm of the DOT Selfie randomized trial in Kamp …

01.09.2026journal-article

Geriatrics

Minimally Invasive Implant Rehabilitation in Geriatric Patients: A Comprehensive Narrative Review of Contemporary Strategies to Avoid Extensive Bone Augmentation Procedures

Angelo Aliberti, Wien Cirine Ben Amor, Mauro Mariniello, Gilberto Sammartino, Oreste Trosino, Francesco Giordano

Background/Objectives: The management of edentulism and severe alveolar bone loss in older adults remains a significant challenge in implant dentistry. Given the potential biological and therapeutic burden associated with extensive regenerative procedures, increasing interest has been directed toward treatment strategies that utilize available anatomy and reduce surgical complexity. This narrative review examined contemporary augmentation-avoidance approaches for implant rehabilitation in geriatric patients. Method …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Fostering Learning and Innovative Behavior in Adult Learners Through Learning and Innovation Platforms

Pongwat Fongkanta, Fisik Sean Buakanok, Suwannee Kruaphung

Transforming local communities to foster sustainable careers for adults through the development of community-driven innovations presents a challenge in this era. This study examines the enhancement and development of community innovation through the Learning and Innovation Platform (LIP), and to investigates the innovative behavior of community members who were developed through the LIP. Participants consisted of 64 community members selected through volunteer sampling. The LIP, including 4 activities, was employed …

02.09.2026journal-article

The Oncologist

21 A Phase II Study of Total Consolidative Metastasis-and-Primary Directed Therapy for Renal Cell Carcinoma (NCT06770855)

Henry Litt, Jeffrey Shevach, Ryan Cobb, Arun Goel, Thomas Guzzo, Daniel Lee, Lin Mei, Ronac Mamtani, Kara Maxwell, Vivek Narayan, John Nikitas, Phillip Pierorazio, Sunil Singhal, Michael Soulen, Spyros Stavropoulos, Samuel Takvorian, Neha Vapiwala, E Paul Wileyto, Alexander Huang, Naomi Haas

Abstract Background Immunotherapy (IO)-based frontline therapy has improved outcomes for patients with metastatic renal cell carcinoma (RCC), with some patients achieving a complete response (CR). Patients who achieve CR are most likely to have sustained responses, whereas patients achieving stable disease (SD) or partial response (PR) often progress despite ongoing therapy. Most progression events occur at pre-existing disease sites, emphasizing the need to augment first-line therapy in this population. Methods Th …

01.09.2026journal-article

Clinical Case Reports

Persistent Post‐Traumatic Brain Injury Hiccups Unresponsive to Standard Agents: Resolution Associated With Levetiracetam Therapy

Rostom Karajeh, Ranya Abu Khalaf, Mostafa Ibraheem Abo Alrob, Saif Khaled Abdalhadi Azzam, Youssef Abdelqader Alsaeed

ABSTRACT Post‐traumatic hiccups are an uncommon but distressing complication of traumatic brain injury (TBI), often resistant to conventional pharmacological agents, and the underlying mechanism may involve central neurological disruption of inhibitory pathways rather than gastrointestinal or metabolic aetiologies. We report a male patient in his early 30s who developed refractory hiccups following moderate TBI sustained in a high‐impact motor vehicle collision; standard agents including chlorpromazine, metoclopram …

01.09.2026journal-article

IJU Case Reports

Immune‐Checkpoint‐Inhibitor‐Related Bullous Pemphigoid During Avelumab Maintenance Therapy in a Patient With Metastatic Renal Pelvic Carcinoma: A Case Report

Taketoshi Nara, Kengo Furihata, Akane Kikuchi, Yuya Sekine, Hiromi Sato, Mizuki Kobayashi, Ryohei Yamamoto, Mitsuru Saito, Shintaro Narita, Tomonori Habuchi

ABSTRACT Introduction Bullous pemphigoid is a rare cutaneous, immune‐related adverse event, and avelumab‐associated cases are extremely rare. Case Presentation A 76‐year‐old man receiving avelumab maintenance therapy for recurrent renal pelvic carcinoma developed pruritic erythema and tense blisters 20 days after the first dose. Laboratory examination showed eosinophilia, increased immunoglobulin E level, and markedly elevated anti‐BP180 antibodies. Moreover, skin biopsy revealed subepidermal blistering with eosino …

01.09.2026journal-article

Journal of Pediatric Gastroenterology and Nutrition

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon

Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is limited. This study aimed to describe rates of steroid‐free clinical remission (CR), endoscopic and histological remission, trends in biochemistry, predictors of resp …

01.09.2026journal-article

International Journal of Innovative Science and Research Technology

A Physiotherapy-Based Analytical Study on Spinal Pain Syndromes: Integrating Core Stabilization, Cervical Mobility Training and Functional Rehabilitation for Low Back Pain and Cervical Spondylosis

Imarn Hussain, Shruti Khandelwal

Background: Recommendations of exercise for chronic spinal pain are contentious due to variances in exercise program specificity, progression, and functional transfer. The purpose of this research was to evaluate an integrated physiotherapy model for chronic low back pain and mechanical neck pain due to cervical spondylosis, which involves core stabilization, cervical mobility and motor-control training, graded functional rehabilitation, and self-management education. This dataset represented 100 patients coming fo …

01.09.2026journal-article

Frontiers in Oncology

CAR-HEMATOTOX score as a predictor of hematotoxicity, infection, and survival after CAR T-cell therapy in hematologic malignancies: a systematic review and meta-analysis

Juncheng Wei, Ziyu Chen, Mengfei Li, Miao Jiang

Background Immune effector cell-associated hematotoxicity (ICAHT) is a common and clinically important toxicity after chimeric antigen receptor (CAR) T-cell therapy. The CAR-HEMATOTOX score, also reported as CAR-HT, is a baseline risk score proposed to identify patients at higher risk of hematotoxicity and related adverse outcomes. Methods We conducted a systematic search of PubMed, the Web of Science, and the Cochrane Library on June 19, 2026. Included studies compared high- and low-risk groups defined by the CAR- …