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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Therapie & Reha · Seite 168

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
13.08.2026journal-article

Working with Older People

Ageing of former manual scavengers in India: occupational health vulnerability, social exclusion and healthy ageing

Aniket Godse, Saikat Deb, Vinod Sharma

Purpose This paper aims to build a conceptual framework to examine the consequences of biological and occupational ageing among former manual scavengers in India. It determines the effects of ageing on social inclusion, perceived dignity, economic security and healthy ageing through considering the mediation of occupational health vulnerability and the moderation of safeguarding mechanisms. Design/methodology/approach This paper summarizes the interdisciplinary literature to hypothesize the conceptual framework tha …

13.08.2026journal-article

The Indonesian Journal of Occupational Safety and Health

Occupational Exposure and Work-Related Factors Associated with Metabolic Syndrome among Vegetable Farmers

Bibit Nasrokhatun diniah, Sulistiyani Sulistiyani, Tri Joko, Budiyono Budiyono

Introduction: Long-term pesticide exposure can harm farmers. Metabolic syndrome (MetS) occurs due to metabolic disorders associated with the use of pesticides which act as diabetogenic and obesogenic agents. High pesticide use and diverse agricultural activities contribute to the increased incidence of MetS. This study aims to examine the associations between history of direct exposure (HDE) and history of indirect exposure (HIE) to pesticide and MetS, as well as to identify factors associated with MetS among farme …

12.08.2026journal-article

Pharmacia

Development and evaluation of clobetasol propionate-loaded nanoliposomal hydrogel integrated with plant-derived microneedle-like microstructures for site-specific psoriasis therapy

Shahad Sadiq Jafer, Yasir Qasim Almajidi

The hyperkeratotic stratum corneum is a principal barrier to the efficient topical treatment of psoriasis and limits drug penetration and therapeutic efficacy. In this regard, the aim of this study was to prepare a new topical delivery system containing clobetasol propionate (CP)-encapsulating nanoliposomes dispersed in Carbopol 940 hydrogel and various plant-derived microneedle-like structures for improved topical drug administration. The optimum formula (F2) had a vesicle size of 100 nm, a low polydispersity inde …

12.08.2026journal-article

Communication and Theater Association of Minnesota Journal

CTAMJ forum on MSHSL activities: Speech

Kathleen Walker, Scott Voss, Tanner Sunderman, Rebecca Meyer-Larson

The CTAM Journal seeks to raise up voices from notable interest groups. Occasionally, individuals are asked to share their thoughts on issues that pertain to the target readership of CTAMJ. For this special forum, four coaches share their voices on Minnesota State High School Speech: Kathleen Walker (Fairmont), Scott Voss (Apple Valley), Tanner Sunderman (Mounds Park), and Rebecca Meyer-Larson (Moorhead).

12.08.2026journal-article

Journal of Ayurveda and Integrated Medical Sciences

Computational Insights on Cow urine distillate used as a Bioenhancer in Cancer Therapy

Prachi Dabhade, Akshata Nandanwar, Amit Nayak, Aliabbas Husain, Nandini Bhojraj, Govind Reddy, U.R. Sekhar Namboori, Dr. Rajpal Singh Kashyap

Cancer poses a significant global health burden, aligning conventional therapies limited by poor drug bioavailability, systemic toxicity, and the development of chemoresistance. The aligning challenges have showcased the growing interest in natural bioenhancers, which are capable of improving therapeutic efficacy while mitigating adverse effects. Cow urine distillate (CUD), a traditional Ayurvedic preparation that is derived from Bos indicus, holds impressive research data in terms of immunomodulatory, antioxidant, …

12.08.2026journal-article

Archives of Medical Science

Safety and efficacy of oncolytic virus therapy in malignant brain tumours: a meta-analysis

Xin Yang, Meng Zhang, Wenjing Zhao, Rong Zhang, Wenbin Li

Introduction Oncolytic virus (OV) therapy has been investigated as a treatment for malignant brain tumours due to its ability to directly induce tumour cell lysis and stimulate antitumor immunity, especially in malignant gliomas. Nonetheless, clinical evidence is primarily derived from small, early-phase trials. We conducted a meta-analysis to consolidate the safety profile and clinical outcomes of OV therapy in patients with malignant brain tumours. Methods We searched PubMed, Embase, Web of Science, Cochrane Libr …

12.08.2026journal-article

MP

SURUNKALI OBSTRUKTIV OʻPKA KASALLIGI VA ZOTILJAMDA ANTIBIOTIKOTERAPIYANING ZAMONAVIY YONDASHUVLARI

Farxod Musayev

Maqolada surunkali obstruktiv oʻpka kasalligi (SOOʻK) kuchayishi va jamiyatda yuzaga kelgan zotiljamni davolashda antibiotikoterapiyaning zamonaviy tamoyillari klinik tajriba va keng adabiyotlar tahlili asosida yoritilgan. Antibakterial dorilarni tanlash mezonlari, davolash davomiyligi, mikrobiologik nazorat masalalari, rezistentlik oldini olish strategiyalari va qoʻshma yurak qon tomir patologiyasi bilan bogʻliq xususiyatlar koʻrib chiqilgan. Oqilona antibiotikoterapiyaning bemor prognoziga taʼsiri asoslangan.

12.08.2026journal-article

Sensors

Tibetan-PASEM: Phonology-Aware Speech Evidence Matching for Low-Resource Tibetan Written-Query Keyword Spotting

Yanze Guo, Xingmeng Guo, Zengguang Li, Jiaxin Song, Yuyang Gong, Guanyu Li

Low-resource written-query keyword spotting detects a text-specified target in speech without spoken enrollment or full automatic speech recognition. We present Tibetan Phonology-Aware Speech Evidence Matching (Tibetan-PASEM), a method that encodes graphemic, approximate phonological, and dialect-related query information, matches it with local acoustic windows, aggregates window-level evidence, and applies a validation-selected operating point. Querybank198 contains 198 Tibetan written queries derived from four pu …

12.08.2026journal-article

Frontiers in Pediatrics

Association of early oxygen therapy parameters with retinopathy of prematurity stages in preterm infants with respiratory distress syndrome: a gestational age-stratified analysis

Shanshan Chen, Rong Li, Na Shi, Qinxing Xie, Wenqiang Liu

Objective To investigate the associations between early oxygen-related parameters and ROP severity in preterm infants with respiratory distress syndrome (RDS), and to evaluate their discriminative performance for severe ROP. Methods This retrospective study included 825 preterm infants (24–<37 weeks) with RDS stratified by gestational age (32–<37, 28–<32, and 24–<28 weeks). Early oxygen parameters during the first 7 days after birth included cumulative oxygen duration, mean and maximum FiO 2 , SpO 2 target range ti …

12.08.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Bone fragility in mastocytosis: Clinical insights from a 5-patient retrospective case series

Dalila Scaturro, Alessandro de Sire, Jessica Accomando, Adele Duca, Maria Silvia Mangano, Michele De Simone, Sofia Tomasello, Giulia Letizia Mauro

Objective This retrospective case series aimed to describe 36-month skeletal, biochemical, safety, and patient-reported outcomes in five postmenopausal women with mastocytosis treated with denosumab. Methods A technical expert panel (TEP) retrospectively evaluated five consecutive eligible patients with osteoporosis associated with indolent systemic mastocytosis. All subjects underwent physiatric assessment, DXA assessment, and Mini-Osteoporosis Quality of Life (Mini-OQoL) evaluation using the validated Italian ver …

12.08.2026journal-article

Diabetes, Obesity and Metabolism

Stage‐Adapted Disease‐Modifying Therapy in Type 1 Diabetes

Chenming Ye, Zhenning Jin, Shen S. Hu

ABSTRACT Aims To propose a stage‐adapted framework for disease‐modifying therapy in type 1 diabetes (T1D) that integrates immune plasticity and residual β‐cell function, and to examine how these evolving constraints may inform treatment selection, combination strategies, and trial endpoints. Materials and Methods This narrative review synthesizes mechanistic, observational, and interventional evidence across presymptomatic T1D, recent‐onset Stage 3 disease, and longer‐duration Stage 3 disease. Evidence relating to …

12.08.2026journal-article

Advanced Science

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li

ABSTRACT The development of high‐performance, environmentally adaptive enzyme‐mimicking catalysts for the treatment of peri‐implantitis (PI) is of great importance yet remains highly challenging. Herein, we report a high‐performance cerium single atom on B, N co‐doped carbon nanotubes enzyme (SAzyme), denoted as Ce‐BNC. Benefitting from its unique N/O‐coordinated electronic environment and reversible Ce 3+ /Ce 4+ redox cycle, Ce‐BNC exhibits an intrinsic pH‐switchable catalytic function, with acidic conditions favo …

12.08.2026journal-article

Current Opinion in Endocrinology, Diabetes & Obesity

Thyroxine withdrawal prior to radioiodine therapy in papillary thyroid carcinoma – current scenarios

Saumya Sunny, Julie Hephzibah

Purpose of review This review aims to compare the different methods of achieving adequate thyroid-stimulating hormone (TSH) stimulation prior to radioiodine (RAI) therapy in patients with differentiated thyroid carcinoma (DTC). It focuses on thyroid hormone withdrawal strategies and recombinant human TSH, examining their relative efficacy, safety, and impact on patient quality of life. Additionally, the review highlights recent guideline updates, and how these approaches influence postoperative risk stratification, …

12.08.2026journal-article

Frontiers in Endocrinology

Long-acting growth hormone therapy in paediatric growth hormone deficiency: reduced treatment burden and unproven motivation-related neuroendocrine effects

Rossella Gaudino, Franco Antoniazzi, Marco Zaffanello, Angelo Pietrobelli, Thomas Zoller, Ruggero Lanzafame, Giorgio Piacentini

Long-acting growth hormone (LAGH) formulations represent an important therapeutic advance in the management of growth hormone deficiency (GHD) because they reduce injection frequency and treatment burden and may improve adherence and patient-reported experience. Beyond these established advantages, we propose a hypothesis-generating framework in which motivation- and reward-related neuroendocrine pathways may interact with hypothalamic regulation of the growth hormone (GH) axis. This review summarises current knowl …

12.08.2026journal-article

Frontiers in Chemistry

Recent advances in photodynamic therapy systems based on pillar[n]arene host–guest chemistry

Fuqiang Zhao, Zhiying Zhu, Liang Li

Photodynamic therapy (PDT) is a minimally invasive and low-toxicity strategy for tumors and bacterial infections. However, conventional small-molecule photosensitizers have poor water solubility, severe aggregation-caused quenching and weak tumor targeting, restricting their clinical translation. Macrocyclic host-guest supramolecular assembly improves the performance of photosensitizers via reversible noncovalent recognition. Pillar[n]arenes feature symmetric electron-rich cavities, abundant modifiable sites and wi …

12.08.2026journal-article

Journal of Midwifery & Women's Health

Differentiating Inflammatory Breast Cancer From Lactational Mastitis: A Diagnostic Challenge

Irena Zakarija‐Grković

Abstract Inflammatory breast cancer (IBC) is a rare but aggressive form of cancer; hence, early diagnosis is essential. Although predominantly occurring in older women, it can occur during pregnancy and lactation, making the diagnosis especially challenging. IBC is characterized by erythema and edema of the breast skin, with or without an underlying palpable mass. In pregnant and postpartum women, it can be easily confused with lactational mastitis. Awareness of the history and clinical signs of IBC, and how it dif …

12.08.2026journal-article

Current Cancer Drug Targets

Targeting Metal-Dependent Cell Death in Cancer: From Molecular Circuitry to Biomarker-Guided Precision Combination Therapy

Xuyang Huang, Xinyue Zhang, Wei Chen, Qi Zhu

Abstract: Cuproptosis and ferroptosis are increasingly recognised not merely as parallel metal-dependent regulated cell death programmes, but as dynamic state variables of tumour metabolism, redox buffering and immune contexture. In this review, we synthesise the field beyond a descriptive pathway summary. We first integrate the core circuitry that governs death susceptibility, including copper trafficking, mitochondrial protein lipoylation and oxidative phosphorylation, iron handling, polyunsaturated-lipid remodel …

12.08.2026journal-article

American Journal of Occupational Therapy

Toward Scalable Driver Readiness Screenings for Autistic Teens: Clinical Measures Correlated With Real-World Evaluations

Chelsea Ward McIntosh, Miriam Monahan, Laura Bennett, Allison E. Curry, Emma B. Sartin

Importance There are no standardized pathways to guide autistic adolescents through the learning-to-drive process, beginning with deciding whether they are ready to pursue driving. Objective To examine whether commonly used clinical assessments correlate with driver readiness determinations. Design Cross-sectional, nonexperimental study using a single in-person visit comprised of a clinical assessment and on-road passenger activities. Setting A primary care clinic in an urban city. Participants Twenty-one autistic …

12.08.2026journal-article

Signal Transduction and Targeted Therapy

From probe to prodrug: immunoproteasome activity as a trigger for disease-selective therapeutics

Cody A. Loy, Yijun Gu, Samuel C. Kim, Mariam V. Mohagheghi, Noah B. Trask, Marina Suarez-Pizarro, Lisa E. Wagar, Claudia A. Benavente, Darci J. Trader

Abstract Developing novel strategies that can exploit a cell's endogenous machinery to selectively release toxic compounds in diseased cells, while leaving healthy cells unaffected, is a challenging task to accomplish. An established approach involves antigen recognition on tumor cells, enabling targeted delivery of prodrugs in which a cytotoxic compound is appended to an antibody by a cleavable linker. However, this strategy depends on the presence of highly expressed surface markers for which antibodies can be de …

12.08.2026journal-article

Cancer Biome and Targeted Therapy

Targeting immune checkpoint B7-H6 in cancer immunotherapy

Ziyi Yang, Qi Zhao

Natural killer (NK) cells are central mediators of antitumor immunity and possess the unique ability to recognize and eliminate malignant cells independently of major histocompatibility complex (MHC) restriction. Compared with T-cell-based approaches, NK-cell immunotherapies generally exhibit a more favorable safety profile, highlighting their growing therapeutic potential in oncology. Among the ligands that regulate NK-cell activity, B7-H6 has emerged as a particularly attractive target because of its highly restr …

12.08.2026journal-article

Journal of Clinical Medicine

Psilocybin-Assisted Therapy in Psychiatry: A Narrative Clinical Review of Mechanisms, Therapeutic Applications, and Emerging Evidence (2025–2026)

Teodora Anghel, Adriana Cojocaru, Lavinia Hogea, Iuliana Costea, Amalia Marinca, Raluca Dumache, Laura Nussbaum, Iuliana-Anamaria Trăilă

Background/Objectives: Psilocybin-assisted therapy has progressed from early proof-of-concept work to a substantially expanded evidence base, with four pivotal studies published in 2025–2026 that were not incorporated into earlier reviews. This review synthesizes the pharmacological and neurobiological foundations of psilocybin and appraises clinical evidence across major depressive disorder (MDD), treatment-resistant depression (TRD), post-traumatic stress disorder (PTSD), cancer-related distress, and substance us …

12.08.2026journal-article

Frontiers in Cardiovascular Medicine

Patent foramen ovale closure versus medical therapy for prevention of recurrent ischemic events in patients with cryptogenic stroke or transient ischemic attack and documented patent foramen ovale: a systematic review and network meta-analysis of randomized controlled trials and observational studies

Yuanpeng Deng, Di An, Xiaoman Xiong, Zhengmei Zhou, Xingde Liu, Yi Xiang

Background This network meta-analysis (NMA) aimed to compare the efficacy and safety of patent foramen ovale (PFO) closure and medical therapy categories, including antiplatelet therapy, anticoagulation, and mixed medical therapy. Methods We systematically searched PubMed, Embase, the Cochrane Library, and Web of Science from inception to June 22, 2026. Eligible randomized controlled trials and observational studies comparing PFO closure with medical therapy in adult patients with cryptogenic ischemic stroke or tra …

12.08.2026journal-article

Molecules

Development and Validation of a Method to Determine CYP4V2 Enzyme Activity in rAAV-hCYP4V2 Gene Therapy Products Using a Bioluminescent Substrate Assay

Yiran Li, Wenhong Fan, Shuting Hou, Yue Ding, Xiuqing Jia, Xi Zhu, Yuemeng Yuan, Yufei Zhang, Yanrong Cao, Xi Qin, Chenggang Liang, Lan Wang

Bietti crystalline dystrophy like retinal degeneration (BCD) is an inherited retinal degenerative disease caused by defects in the CYP4V2 gene. Recombinant AAV-based gene replacement therapy holds promise for this disease, yet reliable enzymatic activity assays for product potency evaluation remain urgently needed. This study established and validated a method for determining the enzymatic activity of CYP4V2 based on the bioluminescent substrate Luciferin-MultiCYP.HEK293-AAVR cells were seeded at 1 × 104 cells/well …

12.08.2026journal-article

South Florida Journal of Environmental and Animal Science

Adjunctive antioxidant therapy in the bidirectional relationship between periodontitis and type 2 diabetes mellitus: a narrative review emphasizing glycemic interaction and metabolic improvement

Suzana Carolina Ramos Silva, Paulo Vinicius de Oliveira Bastos, Pedro Augusto Dias Lima, Rafael Rudimar Holler Peres, Kelly Barbosa Leal Castro, Paula Regina de Souza Inácio, Daniel Domingues S. Junior, Dayane Rosevics Saran Chagas

Periodontitis and type 2 diabetes mellitus (T2DM) are linked by a well-established bidirectional relationship, mediated by hyperglycemia-driven oxidative stress, advanced glycation end-products (AGEs), and chronic low-grade inflammation. Because oxidative stress sits at the mechanistic crossroads of both diseases, adjunctive antioxidant therapies have emerged as a rational strategy to interrupt this cycle. To review current evidence on antioxidant adjuncts to non-surgical periodontal therapy (NSPT) in patients with …