Alle Themen: neue Gesundheitspublikationen – Seite 159

08.09.2026journal-article

Journal of Animal Physiology and Animal Nutrition

Combination of In Ovo Nutritional Components Improves Embryonic Development, Growth Performance, and Gut Health in Broiler Chickens

Derya Yeşilbağ, Fulya Odabaşi Erbay, Ender Deniz Asmaz, Berrin Zik, Artun Yibar, Hilmi Can Acar, Engin Erbay, Kadir Yeşilbağ

ABSTRACT This study evaluated the effects of intra‐amniotic administration of combined energy, amino acid, and vitamin sources on embryonic development, post‐hatch growth performance, and intestinal health in broiler chickens. On Day 18 of incubation, 460 fertile Ross 308 eggs were allocated to four groups: non‐injected negative control (NC), saline‐injected positive control (PC), nutrient solution I (NS‐I; glucose, lysine, and ascorbic acid), and nutrient solution II (NS‐II; creatine monohydrate, glutamine, and as …

08.09.2026journal-article

Brazilian Journal of Health Review

IMPACTO DAS INTERVENÇÕES FARMACÊUTICAS NA OTIMIZAÇÃO DA TERAPIA MEDICAMENTOSA EM PACIENTES COM DISFUNÇÃO RENAL EM UNIDADES DE TERAPIA INTENSIVA EM UM HOSPITAL PÚBLICO NO INTERIOR DE RONDÔNIA

Jéssica Piuna Ragnini, Elissa Gonçalves de Oliveira e Silva, Simone Rosária Soares de Moraes Cunha, Sheila Carminati de Lima Soares, Klaus Rodrigues Tavares, Gustavo Henrique Oliveira Santos, Katiéli Mendes Gomes, Andressa de Jesus Lucio

Considerando que pacientes críticos com disfunção renal apresentam maior risco de eventos adversos a medicamentos, decorrente das alterações farmacocinéticas associadas à redução da taxa de filtração glomerular (TFG), objetiva-se analisar o impacto das intervenções farmacêuticas na otimização da terapia medicamentosa em pacientes com disfunção renal internados em Unidades de Terapia Intensiva (UTI) de um hospital público no interior de Rondônia. Para tanto, procede-se a um estudo de campo, transversal, descritivo e …

08.09.2026journal-article

Pharmaceutical Nanotechnology

Exosome-Based Drug Delivery: Prospects in Regenerative Medicine and Cancer

Pratik Rajale, Nilesh Meshram, Shreya Kalbandhe, Kuldeep Vinchurkar, Laxmikant Borse

Various cell types produce small extracellular vesicles called exosomes, which are becoming more and more popular as natural delivery systems for medicinal compounds in cancer treatment and regenerative medicine. They are ideal drug delivery vehicles because they are stable, have minimal immunogenicity, and can transport a variety of molecules, including proteins, nucleic acids, and small drugs, across biological barriers. Recent developments in bioengineering have produced "designer exosomes" with enhanced cargo-l …

08.09.2026journal-article

Journal of Stroke Medicine

Successful Management of Ischaemic Large Vessel Occlusion and ‘Double’ Prosthetic Valve Thrombosis: Short Report with Systematic Review of Literature

Angel Miraclin T., Anitha Mampilly, Ebenezer Daniel, Santhosh Babu K. B., Selvalakshmi M. Arullselvam, John Davis, Aditya V. Nair, John Jose, Shalini Nair, Shyamkumar Nidugala Keshava, Vivek Mathew, Sanjith Aaron

Background Treatment of embolic events, especially ischaemic stroke with large vessel occlusions (LVOs) in the context of prosthetic valve dysfunction, is a management challenge. Stroke might be the harbinger of prosthetic valve thrombosis. Timely management of ischaemic stroke and prosthetic valve thrombosis is essential to offer optimal outcomes. Methods We report our experience in the management of a young woman, a known patient with rheumatic heart disease, status post double valve replacement (St Jude mechanic …

08.09.2026journal-article

European Journal of Innovation Management

From “data silos” to “data sharing”: public data openness and enterprise ambidextrous innovation

Heng Gu, Yueting Shao, Pengzhen Liu, Le Liu, JiaYu Chen

Purpose This paper examines whether and how public data openness affects firms' ambidextrous innovation in China, distinguishing exploratory innovation from exploitative innovation. Design/methodology/approach Using the staggered rollout of municipal public data platforms as a quasi-natural experiment, this study estimates multi-period difference-in-differences models with Chinese listed firms from 2007 to 2023 and conducts robustness, instrumental-variable, channel, heterogeneity and platform-quality analyses. Fin …

08.09.2026journal-article

Artificial Intelligence in Cancer

Artificial intelligence empowering precision oncology: The convergence and innovation of traditional Chinese medicine and Western medicine wisdom

Chang Qiao, Yu-Tong Han, Jiang-Ping Zhan, Jia Yuan, Xiao-Tong Tian, Yue-Chuan Jiao, Hao-Wei Li, Ling-Yong Wu, Chu Li, Yu-Xuan He, De-Hui Li

The prevention and treatment of malignant tumors remain a major global health challenge. Owing to the marked heterogeneity and dynamic evolution of cancer, conventional diagnostic and therapeutic paradigms are increasingly inadequate for the demands of precision medicine. Artificial intelligence (AI) is accelerating the transition of comprehensive cancer care from experience-driven practice toward data-driven, dynamically supported decision-making. By leveraging machine learning, deep learning, natural language pro …

08.09.2026journal-article

Physics in Medicine & Biology

Analysis of computational methods used to optimize transmission x-ray targets for 100- to 500-kV x-ray tubes

Benjamin Abraham Insley, Mohammad R Salehpour, Dirk Alan Bartkoski

Abstract Objective: While the process of designing a low-to-medium energy transmission X-ray target follows a similar general approach throughout the literature, the specific methodology can vary substantially. The goal of this study was to determine the sensitivity of X-ray target optimization to different methods of X-ray quantification and temperature modeling. Approach: Ultrathin (1.5- to 90-μm) tungsten transmission X-ray targets were modeled in TOPAS (v.3.8) and bombarded with electrons at energies of 10 …

08.09.2026journal-article

Journal of Linguistic Anthropology

Transposition as activism: Toward a public‐facing linguistic anthropology

Mike Mena, Britta Ingebretson

Abstract In 2023, the Demystifying Language Project (DLP) held a 3‐day writing workshop that brought together 12 scholars, paired with 11 undergraduates and 15 high schoolers, to collaboratively recompose their own peer‐reviewed articles into a genre legible to those without specialized training in language‐related disciplines. This was done through transposition as activism , or the process by which participants undermine, transcend, or defect from highly regimented boundaries of academic writing genres and their …

08.09.2026journal-article

Revista ft

Absenteísmo na enfermagem: principais causas de afastamento médico e seus impactos na dinâmica do trabalho hospitalar

Lucely Passos Lopes de Fernandes, Eliane Aparecida Peixoto, Ana Paula de Figueiredo, Flávia Maria Lino, Mônica Martins Moreira Garcez, Maria Lucinete Bentes da Silva, Roberta Camargo Silva, Alice Florentino Echeverria, Carla Andréia de Lima Guimarães, Virgínia Sandri Silva Souza, Margareth Junia da Silva, Oldair Donizete Galeni

Absenteeism among nursing professionals is an important indicator related to occupational health and the organization of hospital services, since sickness absence may reflect working conditions characterized by high physical, emotional, and organizational demands. This study aims to analyze the main causes of medical leave among nursing professionals and their impacts on hospital work dynamics, considering repercussions on staffing, workload among remaining workers, continuity of care, and health service management …

08.09.2026journal-article

PLOS Mental Health

Multi-level mental health-related stigma interventions in healthcare systems through the involvement of people with lived experiences: Mixed-methods pilot findings from international study of discrimination and stigma outcomes (INDIGO) study in Nepal

Bhawana Subedi, Kalpana Bhattarai, Brandon A. Kohrt, Claire Henderson, Elaine Brohan, Graham Thornicroft, Ioannis Bakolis, Maya Semrau, Nicole Votruba, Petra C. Gronholm, Uta Ouali, Dristy Gurung

Mental health-related stigma is a barrier to access to mental health services. This mixed-methods pre-post pilot feasibility study aimed to adapt and pilot-test a multi-level anti-stigma intervention across three levels of the health system to assess its feasibility and potential to reduce mental health-related stigma in Nepal. Contact-based interventions integrating people with lived experience in mental health and stigma training packages were adapted and implemented, targeting female community health volunteers …

08.09.2026journal-article

Emergency Medicine Australasia

Paediatric Procedural Sedation and Analgesia in Emergency Departments: A Delphi Consensus Study

Nuria Cahís, Judith Sánchez‐Manubens, Irene Baena, Aurora Eslava, Eduardo Marín, Adrián Ranera, Roberto Velasco, Raquel Corripio

ABSTRACT Objective To develop a national expert consensus on procedural sedation and analgesia practices in paediatric emergency departments in Spain and identify priority areas for standardisation, safety and implementation. Methods We conducted a modified two‐round Delphi study with a panel of 28 clinicians with expertise in paediatric emergency care and procedural sedation from 23 centres in different regions of Spain. Participants rated key domains related to patient selection, fasting, monitoring, staffing, ph …

08.09.2026journal-article

Courier of Kutafin Moscow State Law University (MSAL))

Public Legal Support for the Digital Transformation of Higher Education in the Russian Federation

R. А. Abdusalamov

The article examines the digital transformation of higher education as a special legal phenomenon in the context of the national development goals of the Russian Federation and the project “Data Economics and Digital Transformation of the State”. Based on the doctrinal approaches of information law, the author distinguishes the concepts of “digitalization” and “digital transformation” in relation to higher education. The article analyzes the public legal mechanisms implemented by federal authorities and subjects of …

08.09.2026journal-article

FUDMA Journal of Sciences

Alternative Approaches to Antibiotics: Phage Therapy, Antimicrobial Peptides, and Phytotherapeutics

Haruna Abdullahi, Haliru Ahmad Kabiru, Habila Mamman Paul, Satvil Dalis James, Taiye Salawudeen Muibat, Uche Samuel Ndidi

Antibiotic resistance has emerged as a critical threat to global health, food security, and economic stability due to the overuse of antibiotics in human medicine and livestock production. This review examines the mechanisms of antibiotic action and resistance, clinical and environmental consequences of resistance, and evaluates current alternative strategies to conventional antibiotics. Bacteria develop resistance through enzymatic degradation, target modification, reduced membrane permeability, alternative metabo …

08.09.2026journal-article

Societies

Social Media Peer Communication and Cholera Risk Perception During the 2024 Outbreak in Lagos, Nigeria: A Health Belief Model Analysis

Agwu Agwu Ejem, Uzoamaka Chioma Ogor, Obioma Rachael Ozioko, Ambrose Onwukaike Igboke, Olushola Ayodeji Akanmode, Chinedu Ibekwe, Somtochukwu Victor Okeke, Charles Chukwudi Eze, Grace Damilola Sam-Olaniyan, Ifeanyi Martins Nwokeocha, Ogochukwu Cynthia Obibuike, Ifeanyi Ebenezer Onyike, Ifunanya Grace Okechukwu

Background: Cholera remains a persistent and deadly global public health challenge. Recent resurgences have caused large-scale outbreaks. Due to gaps in public health risk awareness, effective risk communication using the HBM is now critical for cholera control and prevention. During the 2024 cholera outbreak, Lagos Island residents mainly relied on social media peers to exchange risk information. This study examined cholera risk perception among residents in the hotspot areas, established how the six HBM construct …

08.09.2026journal-article

Journal Pharma Saintika

Analysis of Drug Sales Patterns Based on the Anatomical Therapeutic Chemical (ATC) Classification in a Community Pharmacy: A 2025–2026 Study

Fauziah Hasdin, Andi Amelia Sari Riandika

This study aimed to analyze drug sales patterns based on the Anatomical Therapeutic Chemical (ATC) Level 1 classification at Pharmacy X during the period of June 2025 to June 2026 to support the evaluation of community therapeutic needs and pharmaceutical inventory management. A descriptive observational study with a retrospective approach was conducted using secondary drug sales data. All eligible records were included through total sampling. The collected data consisted of drug names, quantities sold, and transac …

08.09.2026journal-article

Frontiers in Cardiovascular Medicine

Deep septal pacing and subsequent individualized interventricular electrical optimization in HCM with preserved ejection fraction and high anticipated pacing burden: a case report

Ali Hakan Konuş

Management of patients with hypertrophic cardiomyopathy (HCM), preserved left ventricular ejection fraction, and high anticipated ventricular pacing burden remains challenging because current pacing guidelines provide limited direction for this clinical scenario. A 68-year-old man with non-obstructive HCM, symptomatic 2:1 atrioventricular block, and nonsustained ventricular tachycardia underwent implantation of a cardiac resynchronization therapy–defibrillator (CRT-D) system using a lumenless septal pacing lead con …

08.09.2026journal-article

Frontiers in Public Health

Factors and a configurational pathway associated with lower turnover intention among high-level medical professionals in county-level hospitals in China: a multicenter cross-sectional study

Shuxin Dong, Qiuyuan Tai, Yiming Yao, Junlong Shen, Xuemei Huang

Objective This study developed a context-specific framework of perceived conditions related to lower turnover intention among high-level medical professionals in county-level hospitals and examined the configurational pattern associated with a high retention-oriented score. Methods A multicenter cross-sectional study combined three Delphi rounds, psychometric evaluation, and fuzzy-set qualitative comparative analysis (fsQCA). The Delphi process progressed from 33 items in round 1–37 in round 2 and 34 assessed in ro …

08.09.2026journal-article

European Journal of Nuclear Medicine and Molecular Imaging

Biodistribution and radiation dosimetry of the PDGFRβ targeting PET tracer [68Ga]Ga-ATH001

Mark Lubberink, Talakad G. Lohith, Zoltan Derdak, Paul Wilkens, Emilia Palmér, Alexandra Ramolli, Mélodie Ferrat, Thuy A. Tran, Bogdan Mitran, Ayman Abouyzayed, Lars Johansson, Haakan Wennbo, Fredrik Rorsman, Johan Vessby, Olof Eriksson

Abstract Purpose [ 68 Ga]Ga-ATH001 is an Affibody molecule targeting PDGFRβ in development as a Positron Emission Tomography (PET) tracer for non-invasive imaging of active fibrosis. Here we present first-in-human [ 68 Ga]Ga-ATH001 biodistribution and radiation dosimetry data. Methods Radiation dosimetry of [ 68 Ga]Ga-ATH001 was evaluated in healthy participants (n = 3) and participants with metabolic dysfunction-associated steatohepatitis (MASH) (n = 3). Each participant was intravenously administered ~ 2.5 MBq/kg …

08.09.2026journal-article

Frontiers in Psychology

The association pathway between music practice and mental health: a study on social connectedness, perceived stress, and anxiety among individuals with piano experience

Jie Tan

Objective To explore the association pathway between daily participation in music practice and mental health indicators, focusing on analyzing the cross-sectional network relationships among performing flow experience, social connectedness, perceived stress, and anxiety among individuals with piano experience. Methods A cross-sectional online survey design was adopted, yielding a total of 890 valid questionnaires. Based on the presence or absence of piano practice experience, the sample was divided into two questio …

08.09.2026journal-article

Lecture Notes in Education Psychology and Public Media

Transgenerational Inheritance of Odour-Specific Fear Memory

Vivian Zhu

Transgenerational epigenetic inheritance suggests that environmental experiences can influence offspring biology through mechanisms that do not involve changes to DNA sequence. Previous studies have demonstrated that paternal fear conditioning to a specific odour can alter offspring sensitivity and behavioural responses to that same odour, indicating that parental experiences may be transmitted across generations. However, the neural mechanisms underlying these effects remain poorly understood. This study investiga …

08.09.2026journal-article

Discover Public Health

Benzodiazepine use across the legal and illegal continuum in Europe and implications for clinical burden and deprescribing

Jose Seijas-Amigo

Abstract Benzodiazepines (BZDs) remain widely used across Europe for anxiety, insomnia, and related indications, despite longstanding recommendations limiting treatment duration and prioritising non-pharmacological care. Alongside sustained prescribing, Europe is characterised by a “legal–illegal continuum” in which authorised medical use, diversion and non-medical consumption, and illicit markets—including novel BZDs monitored as new psychoactive substances—interact and amplify clinical harm. Recent European data …

08.09.2026journal-article

SKIN The Journal of Cutaneous Medicine

Characteristics of Emergency Department Patients Seeking Dermatologic Care Using 2022 National Hospital Ambulatory Medical Care Survey Data

Alexander Gomez-Lara, Noel Vargas, Jason Castillo, Paradi Mirmirani

Emergency department (ED) visits often serve as a safety net for patients with limited access to outpatient dermatologic care. Racial and ethinci minorities experience disproportionate barriers to dermatologic diagnosis, treatment, and specialty access. We evaluated racial/ethnic differences in ED visits identifying primary clinician-rendered dermatologic visits using the 2022 National Hospital Ambulatory Medical Care Survey (NHAMCS). Patient demographics, residence, and payment source were stratified by race and s …

08.09.2026journal-article

Frontiers in Immunology

Oncolytic bacteria therapy for malignant glioma

Feiyue Li, Jing Zhao, Ang Ji, Junlong Zhao, Sanzhong Li

Malignant glioma is a group of primary malignant tumors of the central nervous system with an extremely poor prognosis, with glioblastoma being the most malignant type. Its highly invasive nature, tumor heterogeneity, stubborn immunosuppressive microenvironment, and the barrier effect of the blood-brain barrier result in limited efficacy of traditional surgery, radiotherapy, and chemotherapy, leading to high recurrence rates and short survival times. The tumor hypoxic microenvironment, as a core cause of treatment …

08.09.2026journal-article

Clinical and Experimental Dermatology

Real-world Drug Survival of Guselkumab in Patients With Psoriasis Stratified by Weight and Comorbidities: Retrospective, Observational Data From the British Association of Dermatologists Biologics and Immunomodulators Register

Laura Savage, Maria-Angeliki Gkini, Xiayi Wang, Louise Topping, Bhavika Chauhan

Abstract In the United Kingdom (UK), 89.1% of patients with moderate-to-severe psoriasis are overweight or obese, and 53.2% have at least one comorbidity. However, real-world data on biologic-treated patients with psoriasis and comorbidities remains limited. Objectives were to compare 36-month drug survival of guselkumab in patients across weight and body mass index (BMI) categories, and in those with or without specific comorbidities. This retrospective cohort study used data from the British Association of Dermat …

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Combination of In Ovo Nutritional Components Improves Embryonic Development, Growth Performance, and Gut Health in Broiler Chickens

IMPACTO DAS INTERVENÇÕES FARMACÊUTICAS NA OTIMIZAÇÃO DA TERAPIA MEDICAMENTOSA EM PACIENTES COM DISFUNÇÃO RENAL EM UNIDADES DE TERAPIA INTENSIVA EM UM HOSPITAL PÚBLICO NO INTERIOR DE RONDÔNIA

Exosome-Based Drug Delivery: Prospects in Regenerative Medicine and Cancer

Successful Management of Ischaemic Large Vessel Occlusion and ‘Double’ Prosthetic Valve Thrombosis: Short Report with Systematic Review of Literature

From “data silos” to “data sharing”: public data openness and enterprise ambidextrous innovation

Artificial intelligence empowering precision oncology: The convergence and innovation of traditional Chinese medicine and Western medicine wisdom

Analysis of computational methods used to optimize transmission x-ray targets for 100- to 500-kV x-ray tubes

Transposition as activism: Toward a public‐facing linguistic anthropology

Absenteísmo na enfermagem: principais causas de afastamento médico e seus impactos na dinâmica do trabalho hospitalar

Multi-level mental health-related stigma interventions in healthcare systems through the involvement of people with lived experiences: Mixed-methods pilot findings from international study of discrimination and stigma outcomes (INDIGO) study in Nepal

Paediatric Procedural Sedation and Analgesia in Emergency Departments: A Delphi Consensus Study

Public Legal Support for the Digital Transformation of Higher Education in the Russian Federation

Alternative Approaches to Antibiotics: Phage Therapy, Antimicrobial Peptides, and Phytotherapeutics

Social Media Peer Communication and Cholera Risk Perception During the 2024 Outbreak in Lagos, Nigeria: A Health Belief Model Analysis

Analysis of Drug Sales Patterns Based on the Anatomical Therapeutic Chemical (ATC) Classification in a Community Pharmacy: A 2025–2026 Study

Deep septal pacing and subsequent individualized interventricular electrical optimization in HCM with preserved ejection fraction and high anticipated pacing burden: a case report

Factors and a configurational pathway associated with lower turnover intention among high-level medical professionals in county-level hospitals in China: a multicenter cross-sectional study

Biodistribution and radiation dosimetry of the PDGFRβ targeting PET tracer [68Ga]Ga-ATH001

The association pathway between music practice and mental health: a study on social connectedness, perceived stress, and anxiety among individuals with piano experience

Transgenerational Inheritance of Odour-Specific Fear Memory

Benzodiazepine use across the legal and illegal continuum in Europe and implications for clinical burden and deprescribing

Characteristics of Emergency Department Patients Seeking Dermatologic Care Using 2022 National Hospital Ambulatory Medical Care Survey Data

Oncolytic bacteria therapy for malignant glioma

Real-world Drug Survival of Guselkumab in Patients With Psoriasis Stratified by Weight and Comorbidities: Retrospective, Observational Data From the British Association of Dermatologists Biologics and Immunomodulators Register