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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
14.08.2026journal-article

Journal of Acute Care Physical Therapy

Development of Interprofessional Collaboration and Communication Through Simulation-Based Learning Experiences for Physical Therapy and Speech-Language Pathology Learners

Sheri R. Kiami, Sarah Young-Hong, Wendy C. Georgan, Heidi Cheerman

ABSTRACT Background and Purpose: Literature has shown that interprofessional simulation-based learning experiences (Sim IPE) are effective at preparing future healthcare providers for interprofessional practice and an impactful way to meet health professions’ accreditation standards. However, there is a lack of literature examining outcomes of Sim IPE among entry-level Doctor of Physical Therapy (DPT) and Master of Science Speech-Language Pathology (MS-SLP) learners. The purpose of this study is to examine how part …

14.08.2026journal-article

Veterinary Medicine and Science

Adjunctive Therapy With a Perna canaliculus and Euphausia superba Extract (EAB‐277 TM ) for Clinical Signs of Tracheal Collapse in Dogs: A Prospective, Randomized and Placebo‐Controlled Exploratory Trial

Wasutorn Yangwanitset, Somkiat Huaijantug, Mookmanee Taechikantaphat, Melanie Hezzell, Walasinee Sakcamduang

ABSTRACT Background Tracheal collapse is a common canine respiratory disease characterized by dorsoventral cartilage flattening, airway lumen narrowing and subsequent mucosal inflammation. Objectives To investigate the efficacy of EAB‐277, a marine lipid extract combining Perna canaliculus (30 mg) and Euphausia superba (20 mg) as an adjunctive therapy in the management of tracheal collapse in dogs. Methods Forty‐one dogs with confirmed tracheal collapse were randomly assigned to receive standard conventional medica …

14.08.2026journal-article

American Journal of Speech-Language Pathology

Paired-Comparison Versus Cross-Sectional Approaches for Assessing Longitudinal Speech Change in Parkinson's Disease Following Deep Brain Stimulation of the Subthalamic Nucleus

Jordan L. Manes, Andrea H. Rohl, Mengyang Qiu, Kaila L. Stipancic, Daniel M. Corcos, Charity G. Patterson, Jeremy D. W. Greenlee, Kris Tjaden

Purpose: Longitudinal changes in perceptual speech outcomes are typically derived from independent judgments at each time point rather than side by side within-speaker comparisons. This study evaluated a paired-comparison method for detecting longitudinal speech change in Parkinson's disease (PD) across three perceptual constructs (intelligibility, listener effort, and severity) relative to a cross-sectional method for detecting speech changes in the same cohort. Method: We collected recordings of the Speech Intell …

14.08.2026journal-article

Annals of African Medicine

Clinico-epidemiological Profile and Outcome of Severe Acute Malnutrition Children Admitted to the Nutritional Rehabilitation Center of a Tertiary Care Center in Kalaburagi, Karnataka: A Retrospective Study

K. S. Sreeshyam, N. A. Gururaj, S. Sangita, H. Ramesh, Ajaykumar Gududur

Abstract Introduction: Severe acute malnutrition (SAM) continues to be one of the most important preventable causes of under-five morbidity and mortality in low- and middle-income countries, particularly in South Asia, a significant proportion of which is contributed by India. Nutritional rehabilitation centers (NRCs) deliver standardized care for children with SAM using guidelines derived from the World Health Organization (WHO); however, there is a paucity of data regarding their functioning in Karnataka and Sout …

14.08.2026journal-article

PLOS One

Factors associated with return to pre-admission functional category at hospital discharge among acute inpatients receiving physical therapy and/or occupational therapy: A retrospective cohort study

Yazeed Temraz, Wafa Bin Salamh, Naif Alsayahi, Mohammed Alrehaili, Fahdah Aljamaan, Hend Alqudaimi, Dina Alqueflie

Background Functional decline associated with acute hospitalization may persist at hospital discharge. This study examined associations between routinely documented admission-time characteristics and return to the same pre-admission functional category among acute inpatients receiving physical therapy and/or occupational therapy. Methods This exploratory single-center retrospective cohort study included 444 unique adults who received acute inpatient physical therapy and/or occupational therapy at a tertiary hospita …

14.08.2026journal-article

International Journal For Multidisciplinary Research

Run Smart, Run Strong: Exploring the Role of Physiotherapy in Running Load Management and Injury Prevention Among Recreational Runners

Ruchita Handore, Aditi Davane, Shashwat Joshi, Priyanranjan Chaudhary

Background Running is a widely practiced form of physical activity among recreational runners; however, inappropriate training load and inadequate progression may contribute to running-related injuries. Physiotherapy may play an important role in optimizing running load, improving physical capacity, and preventing running-related injuries through strengthening, flexibility, neuromuscular, and load-management strategies. Therefore, this narrative review aimed to explore the role of physiotherapy in running load mana …

14.08.2026journal-article

Journal of VitreoRetinal Diseases

Sequential Application of Transpupillary Thermal Therapy and Cryotherapy in the Management of Small Choroidal Melanoma: A Pilot Evaluation of Efficacy and Safety

Jessica Henry, Thomas M. Aaberg

Purpose: To evaluate whether transpupillary thermal therapy and cryotherapy could improve control of small choroidal melanoma and reduce scleral extension risk. Methods: A retrospective review identified 30 patients with clinically diagnosed unilateral choroidal melanoma treated sequentially with transpupillary thermal therapy and cryotherapy between 2001 and 2025. Data collected included demographics, tumor characteristics, treatment response, complications, visual acuity, metastasis, and mortality. Treatment fail …

14.08.2026journal-article

International Journal of Advanced Research in Commerce, Management & Social Science

Essential Commodities and Household Adaptation: Framing Family Economy Rhythm Therapy as a Coping Paradigm

M Balagopal

Family budgets are getting affected more and more by price instability of essential commodities, including coconut oil, onions, cooking gas, and petrol. The price rises of 200–300 percent recently seen have made family budgets unstable and compelled people to find ways that gradually bring back normalcy. This research paper proposes the idea of Family Economy Rhythm Therapy (FERT), which is based on the idea of Social Rhythm Therapy, to illustrate how families adjust to such economic shocks. With the help of instan …

14.08.2026journal-article

BMJ Supportive & Palliative Care

Time toxicity in patients receiving brachytherapy and hormonal therapy for recurrent prostate cancer: a cohort study

Ronald Chow, Sarah Bayrakdarian, Camilla Zimmermann, Georgia C Richards, Carl Heneghan, Jennifer Leigh, Hans Chung

Objectives Time toxicity—the time patients spend receiving treatment and associated care—is an increasingly recognised burden of cancer treatment. Literature has largely relied on calendar-day–based measurement, which may obscure meaningful variation in time burden. This study aimed to quantify time toxicity with greater granularity by measuring it in hours. Methods We conducted a retrospective cohort study of patients with recurrent prostate cancer enrolled in a clinical trial of concurrent high-dose-rate brachyth …

14.08.2026journal-article

British Journal of Clinical Pharmacology

Twenty years of inhaler therapy: A nationwide drug utilization study

Katrine Bitsch Johansen, Lars Christian Lund, Zandra Nymand Ennis, Andrew Scourfield, Anders Løkke, Sidsel Arnspang Pedersen

Aims This study aimed to map nationwide trends and prescribing patterns in inhaler use from 2004 to 2023. In light of evolving clinical guidelines and attention to the environmental impact of inhalers within recent years, we also examined variation in prescribing behaviour and patient‐level treatment choices. Methods Using nationwide health registries, we identified all individuals redeeming prescriptions for pressurized metered‐dose inhalers (pMDIs), dry powder inhalers (DPIs) and soft mist inhalers (SMIs) in Denm …

14.08.2026journal-article

Hygiene and sanitation

Myocardial and microvascular remodeling in dust-related lung pathology as a morphological substrate of occupational cardiomyopathy in miners

Oleg I. Bondarev, Egor S. Filimonov

Introduction. Heart diseases are the leading cause of death among miners (>60%). Between 2000 and 2016, 1,797 acute cardiovascular events occurred at the workplace, including 467 fatal cases. These are usually classified as ischemic heart disease, but this is not confirmed by microscopy and does not account for direct damage to the heart by coal-rock dust.Objective. To provide microscopic evidence for defining “dust cardiomyopathy” as a distinct occupational heart disease.Materials and methods. Heart tissue from 80 …

14.08.2026journal-article

International Journal of Traditional and Complementary Medicine Research

One-Year Outcomes of Bioresonance Therapy for Smoking Cessation: A Prospective Primary Care Study

Gamze Dur, Nazlı Şensoy

Aim: Tobacco use remains a major global health concern. Despite pharmacological advances, many smokers seek non-invasive interventions due to side-effect concerns. This study evaluated the 1-year effectiveness of a standardized biophysical therapy, namely Bioresonance Therapy (BRT), for smoking cessation in a primary care setting.Material and Methods: In this prospective longitudinal study, 50 adult participants (mean age 44.3 ± 10.4) underwent a standardized BRT protocol. Nicotine dependence was assessed using the …

14.08.2026journal-article

ACS Applied Materials & Interfaces

Multifunctional MoO3− X Nanozyme-Hydrogel for Synergistic Photothermal Antibacterial Therapy and Enhanced Healing of Wounds Infected with Drug‑Resistant Bacteria

Weiwei Zhang, Lixiang Fan, Xuanjun Zhang, Hongyan Lu, Longbao Zhu, Ping Song, Fei Ge, Dongdong Sun, Wanzhen Li

Abstract Multidrug-resistant (MDR) bacterial infections and recalcitrant biofilms remain intractable barriers to wound healing, with traditional antibiotics offering limited efficacy due to resistance and poor biofilm penetration. To address this unmet clinical need, we innovatively engineered a multifunctional composite hydrogel (MoO3−X@CG-ODP) by integrating oxygen-vacancy-rich MoO3−X nanozymes into a dynamic cross-linking network formed by L-glutamine-grafted chitosan (CG) and 3-aminophenylboronic acid-mediated …

14.08.2026journal-article

Journal of Pharmaceuticals and Natural Sciences

Review: Drug Interactions Between Depression and Epilepsy Therapy

Erwin Samsul, Sandrina Nur Yulianda, Rahmawati Eka Sari, Dina Nurfauziah Rahmi, Rahma Nur Afifah, Risma Nur Ramadhani, Annisa Azhalia Syakina, Selvina Nirmaya Saputri, Listra Febrina Taruk

Background: Managing comorbid depression and epilepsy is challenging due to complex drug-drug interactions (DDIs). Objective: This systematic review evaluates clinically significant pharmacokinetic and pharmacodynamic interactions between antidepressants and antiepileptic drugs (AEDs). Methods: A systematic search was conducted across PubMed, ScienceDirect, and Google Scholar (2010–2025) following PRISMA guidelines. Results: Of 377 identified records, 24 studies met the inclusion criteria. Pharmacokinetic interacti …

14.08.2026journal-article

ACS Omega

Mining of Novel Human DPP-IV-Targeting Tripeptides through Multicomputational Screening and In Vitro Validation for Diabetes Therapy

James V. Lavilla, Francis Kirby B. Burnea, Hironobu Hojo, Changge Guan, Charlie A. Lavilla

Abstract Inhibition of human dipeptidyl peptidase IV (hDPP-IV) is considered an effective strategy in the management of type 2 diabetes (T2D). However, the lack of high-throughput screening approaches and the high cost of experimental evaluation have limited the discovery of peptide-based hDPP-IV inhibitors. Herein, an integrated multicomputational screening strategy was employed to successfully mine novel hDPP-IV inhibitory tripeptides. Among the screened candidates, FAW exhibited the highest inhibitory activity, …

14.08.2026journal-article

Russian Journal of Skin and Venereal Diseases

Comparative efficacy of photodynamic therapy, autologous platelet-rich plasma therapy, and their combination in the treatment of diffuse telogen effluvium

Farah Bedoui, Vladimir B. Pineguin, Viktoria M. Poglazova, Olga V. Cergeeva

Background. Diffuse telogen effluvium accounts for a significant proportion of visits to trichologists and reduces the quality of life of patients. However, comparative data on the effectiveness of various physiotherapeutic methods for this condition remain limited. Photodynamic therapy and PRP therapy are considered promising methods for stimulating hair growth by targeting various pathogenesis factors, but the feasibility of their combined use remains poorly understood. AIM:To evaluate the clinical efficacy of ph …

14.08.2026journal-article

Analytical Chemistry

Evaluation and Optimization of Different Digestion Strategies for In-Depth Proteomic Characterization of Residual Host Cell Proteins in rAAV-Based Gene Therapy Products

Kathrin Viodé, Timo Bohlig, Fabienne Intlekofer, Roberto Falkenstein, Marco Thomann

Abstract Recombinant adeno-associated virus vectors (rAAVs) are the most important vectors for in vivo gene therapies, yet their safety relies on low levels of residual host cell proteins (HCPs). While mass spectrometry-based proteomics enables sensitive and untargeted HCP profiling, it faces challenges with matrix interferences from purification buffers and the high dynamic range between abundant viral capsids and trace HCPs. Although sample preparation methods that address these challenges are well-established fo …

14.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Acute adaptations in dynamic torque and torque control to practicing with known and unknown sequences of concentric and eccentric muscle contractions in healthy young adults

Balázs Gáspár, Sarolta Tar, Ádám Fésüs, Patrik Ivusza, Mátyás Varga, Balázs Sebesi, Zsolt Murlasits, Anikó Kőnig-Péter, Tibor Hortobágyi, Márk Váczi

Abstract Background During human movement, the neuromuscular system continuously adapts to varying and differently predictable demands. Practicing with sequences of known and unknown types of muscle contractions could train force control of muscle. We compared the acute effects of practicing with eccentric and concentric quadriceps muscle contractions at different velocities with known and unknown sequences, on knee extension torque, torque steadiness, and joint position sense in healthy young adults. Methods Ninet …

14.08.2026journal-article

International Journal of Offender Therapy and Comparative Criminology

Exploring the Truths of Moral Reconation Therapy: A Dialogical Narrative Analysis of the Voices of Women on Probation and Facilitators

Vanessa Lynn, Addrain Conyers

This study examines Moral Reconation Therapy (MRT) as a mandated narrative intervention focusing on how women on probation and MRT facilitators make sense of its emphasis on responsibility, honesty, and trust. Drawing on interviews with eight women on probation and two MRT facilitators at a Women Reentry Project, we conduct a dialogical narrative analysis. This approach examines how multiple, sometimes competing, voices emerge within the clients’ accounts and those of the facilitators. Women frequently draw on inst …

14.08.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Development and validation of the arabic version of the Spine Functional Index (SFI-AR) in patients with spinal disorders

Marc Boutros, Guy Awad, Caren Hassan, Shaza Hammad, Tia-Maria Akoury, Zina Smadi, Rami Rachkidi

Background The Spine Functional Index (SFI) is a patient-reported outcome measure used to evaluate functional limitations in patients with spinal disorders. However, no validated Arabic version has been available, limiting standardized assessment in Arabic-speaking populations. Methods This prospective cross-sectional validation study translated and culturally adapted the SFI into Arabic (SFI-AR) following internationally accepted guidelines, including forward and back-translation, expert committee review, and pilo …

14.08.2026journal-article

Hygiene and sanitation

The impact of occupational experience on the development of circulatory system pathology in workers in the coal mining industry

Egor S. Filimonov, Olesya A. Rumpel, Oleg I. Bondarev

Introduction. Primary prevention of circulatory system diseases is extremely important due to the additional impact of harmful industrial factors on the body, which can accelerate the development of cardiovascular pathology in workers of industrial enterprises.The aim of the study was to investigate the incidence of atherosclerosis and premorbid heart failure in coal mining workers, depending on their occupation and the duration of exposure to harmful industrial factors.Material and methods. Four hundred ninety sev …

14.08.2026journal-article

International Journal of Educational Teaching and Research

Discussion on the Sports and Exercise Rehabilitation Majors in New Zealand Universities and their Relationships with Aging Society

Man Li, Xu Dai

With the increase in the number of older people around the world, problems in their health have attracted more attention from society. Sports and exercise rehabilitation play an essential role in improving the physical fitness, boosting the mental health and overall quality of life of older people, and thus have gradually become important ways to address the health problems of an aging society. As the main institutions for knowledge innovation and talent cultivation, universities in New Zealand have achieved good r …

14.08.2026journal-article

JCC Plus

Hepatitis E Infection in Patients With IBD Treated With Advanced Therapy: A Case Series

Jakub Jirsa, Kristyna Kubickova, Dana Duricova

ABSTRACT Background and Aims Hepatitis E virus is an RNA virus with 8 genotypes. Infection is usually acute and asymptomatic, but chronic infection may develop in immunocompromised individuals. Data on the course of hepatitis E virus infection in patients with inflammatory bowel disease receiving advanced therapy are limited. We aimed to describe the clinical course and outcomes of hepatitis E virus infection in this population. Methods We conducted a case series of consecutive patients with inflammatory bowel dise …

14.08.2026journal-article

ACS Applied Materials & Interfaces

Ingestible Hydrogel-Encapsulated Optogenetic Yeast Controlled by Wearable Electronics Enables Programmable IL-10 Delivery for Inflammatory Bowel Disease Therapy

Chao Zhang, Hongxiang Li, Yue Jiang, Lu Wang, Zhijie Feng, Yanyan Shi, Duo Liu, Hanjie Wang

Abstract Engineered yeast-living drugs offer significant potential for oral protein therapy but remain limited by poor intestinal retention and lack of precise spatiotemporal control over therapeutic delivery. Here, we developed an ingestible hydrogel-encapsulated optogenetic yeast system controlled by a wearable electronic device for programmable interleukin-10 (IL-10) delivery in inflammatory bowel disease (IBD). We engineered Pichia pastoris with an EL222-based blue-light-inducible circuit achieving rapid, strin …