JAMA Cardiology
Effect of Acoramidis on Heart Failure–Related Health Status
Importance In patients with transthyretin amyloid cardiomyopathy (ATTR-CM), acoramidis achieves near-complete (≥90%) transthyretin stabilization and reduces mortality and cardiovascular-related hospitalizations; however, its effect on patient-reported health status has not been comprehensively described. Objective To evaluate the effect of acoramidis on heart failure (HF)–related health status as assessed by the Kansas City Cardiomyopathy Questionnaire Overall Summary score (KCCQ-OS) in patients with ATTR-CM. Desig …