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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
14.08.2026journal-article

Journal of Health Economics and Outcomes Research

Cognitive Behavioral Therapy in Early Intervention for Psychosis: A Cost-Effectiveness Analysis

Maximilian Duckworth, Sofia Venturini, Andres Roman-Urrestarazu

Background: Early intervention for psychosis (EIP) is a multidisciplinary service that treats individuals experiencing early psychosis. Treatment often consists of pharmacotherapy and cognitive behavioral therapy for psychosis (CBTp). While EIP demonstrates clinical efficacy and cost-effectiveness as a comprehensive package, the incremental contribution of its individual components remains unclear. With mental health services facing sustained funding pressures, understanding which EIP elements offer value for money …

14.08.2026journal-article

Frontiers in Public Health

When knowledge is not enough: infection prevention and control practices and occupational biological exposures among dental professionals in Zimbabwe

Tanusha Singh, Kundai Mavis Makozho

Background Dental professionals are routinely exposed to occupational biological hazards, yet evidence from low-resource settings remains limited. This study assessed infection prevention and control (IPC) knowledge and practices, quantified occupational biological exposures, and identified factors associated with sharps injuries and occupational infections. Methods A cross-sectional analytical study was conducted among 220 dental professionals in Bulawayo, Zimbabwe. Data were collected using a structured self-admi …

14.08.2026journal-article

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan

Potential Benefits and Mechanisms of Yoga Therapy For Chronic Low Back Pain: A Narrative Review

Ni Made Rahajeng Ayu Narayani, Made Kurnia Widiastuti Giri, Made Pradnyandari Adiswarya Putri, Putu Elfira Pratiwi, Luh Putu Prema Sutayani, I Gede Satria Dharma Wijaya

Chronic low back pain (CLBP) is a common condition that can significantly impact physical function, psychological health, and overall quality of life, highlighting the need for effective non-pharmacological treatments. Yoga, which integrates physical postures, breathing techniques, and relaxation, may help address various aspects of chronic pain. This narrative review synthesizes potential clinical benefits and mechanisms of yoga therapy for CLBP, drawing from studies published between 2016 and 2025 sourced from Pu …

14.08.2026journal-article

Medicine

A study on the effect of posture-recognition-based mirror visual feedback therapy on balance function and activities of daily living in patients with poststroke neglect

Juan Jin, Hongji An, Juanxiu Cui, Long Piao

This study aimed to investigate the effects of posture-recognition-based mirror visual feedback therapy (MVFT) on the degree of neglect, balance function, and activities of daily living in patients with poststroke neglect. A retrospective cohort study design was employed. Patients with poststroke neglect admitted to the Department of Rehabilitation Medicine of our hospital from May 2023 to May 2025 were selected and divided into a feedback therapy group and a conventional rehabilitation group based on whether they …

14.08.2026journal-article

Journal of Modern Education and Culture

Developing Trends of Sports Rehabilitation Programs in New Zealand Higher Education Institutions in the Context of Population Aging

Xu Dai, Shan Jiang

As the world's population is ageing, so too has New Zealand's problem of an aging society. As the proportion of older people in society has been increasing, so too has the demand for health and medical services for older adults. As a scientific way to help people, exercise rehabilitation can boost the physical strength, bone density and other functions of older adults to slow down age-related decline and improve their quality of life. Research on the role of sports rehabilitation programs in New Zealand's universit …

14.08.2026journal-article

The BRICS Health Journal

Analysis of the CAR-T cell therapy landscape in Russia

Dmitry G. Shchurov, Igor N. Mizin

The objective of this study was to provide a comprehensive overview of the CAR-T (chimeric antigen receptor T-cells) therapy landscape in Russia, including the types of products used, their target antigens, indications, the role of CAR-T therapy in treatment pathways, clinical trials, marketing authorization, and production infrastructure data. A key feature of the Russian landscape is the emergence of a hybrid ecosystem in which academically developed products coexist with the first industrial CAR-T products. Mono …

14.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

The effect of SportsMetrics training program on functional performance, landing error, dynamic knee valgus and hamstrings/quadriceps strength in athletes: a systematic review and meta-analysis

Fereshteh Kazemi pakdel, Ahmad Kazemi pakdel, Elham Hajihoseini, Mohamad Mottaghitalab, Hamed Zarei

Abstract Objective The SportsMetrics training (SMT) program is a comprehensive injury prevention initiative designed for athletes, focusing on improving strength, flexibility, and overall performance through targeted exercises and assessments. Therefore, the purpose of this systematic review is to examine the effect of SMT program on functional performance, landing error, dynamic knee valgus and hamstrings/quadriceps strength ratio in athletes. Methods Primary sources were sourced from four databases: SCOPUS, PubMe …

14.08.2026journal-article

Acta Mechanica et Automatica

Method for Improving Muscular Activations during Exoskeleton-Aided Therapy with Intelligent Algorithms and VR-Based Teleoperation

Piotr FALKOWSKI, Kajetan JEZNACH, Tomasz OSIAK, Jan OLEKSIUK, Krzysztof ZAWALSKI, Piotr KOŁODZIEJSKI, Daniel ŚLIŻ, Zbigniew PILAT, Tomasz CHOMIUK

Population ageing, neurological and orthopaedical diseases, and shortages in medical staff result in the need to develop tools for minimally su-pervised therapy. To guarantee effective kinesiotherapy in high doses, rehabilitation robots are required. However, they require additional tech-nologies for automating treatment and monitoring patients' safety. This paper presents and assesses such technologies integrated with the SmartEx-Twin exoskeleton of a lower extremity and its digital twin in virtual reality (VR) fo …

14.08.2026journal-article

Archives of Mental Health

Acute dystonia following occupational inhalation of risperidone powder in a pharmaceutical trainee chemist

Anand Bhogaraju, Yasaswi Kadaru, Tabitha Jezreel, Kamma Vishnu Tulasi

Abstract Risperidone is an atypical antipsychotic whose occupational hazards, particularly via inhalation, are under-recognized. We report the case of a 22-year-old male trainee chemist in a pharmaceutical company who developed acute dystonia after unintentional inhalation of risperidone powder while working in a dryer room without adequate respiratory protection. Symptoms, including orofacial deviation, jaw clenching, torticollis, hand tremors, giddiness, tachycardia, and hypertension, began approximately 1 h post …

14.08.2026journal-article

Current Psychiatry Reports

Eating Disorder Focused Family Therapy with Autistic Children and Young People: A Narrative Review of Recent Developments

Amelia Austin, Rachel Loomes, Fiona Duffy

Abstract Purpose of review This review aims to report the recent advances for eating disorder focused family therapy (FT-ED) for Autistic children and young people, including outcomes, experiences, and suggested adaptations. Recent findings Quantitative studies suggest that Autistic children and young people (and those with high autistic traits) receiving outpatient FT-ED are more likely to require escalation to more intensive levels of care compared to non-autistic peers. Qualitative research shows that Autistic y …

14.08.2026journal-article

International Forum of Allergy & Rhinology

Clinical Improvement and Immune Signatures Following Platelet‐Rich Plasma Therapy for Post‐Viral Olfactory Dysfunction

Vivienne M. Li, Jennifer S. Lee, Arwa Kurabi, Thomas Zhou, Farhoud Faraji, Carol H. Yan

ABSTRACT Background Platelet‐rich plasma (PRP) has emerged as a promising therapy for post‐viral olfactory dysfunction (PVOD) though its biological mechanisms remain unclear. This study evaluated clinical outcomes and targeted proteomic changes following PRP for refractory PVOD. Methods Adults with PVOD ≥ 6 months refractory to standard therapies underwent a single bilateral PRP injection into the olfactory clefts. Demographics, subjective olfactory ratings, and psychophysical assessment using the University of Pen …

14.08.2026journal-article

Cerrahpaşa Medical Journal

Effect of Maintenance Anti-EGFR Therapy on Survival in RAS Wild-Type Metastatic Colorectal Cancer: Real-World Data

Simay Çokgezer, Selay Artan, Sevde Topuz, Muhammet Şenkal, Abdulmunir Azizy, Burak Şakar, Didem Taştekin, Senem Karabulut

Objective: This study aimed to evaluate the impact of anti-epidermal growth factor receptor (anti-EGFR)–based maintenance therapy administered after first-line chemotherapy combined with anti-EGFR treatment on progression-free survival (PFS) and overall survival (OS) in patients with RAS wild-type metastatic colorectal cancer (mCRC), using real-world data. Methods: Patients followed at a single center between 2015 and 2025 were retrospectively analyzed. A total of 37 RAS wild-type patients who achieved disease cont …

14.08.2026journal-article

Robotics

Advances in Pneumatic Upper-Limb Rehabilitation Robots: A Critical Review of Structural Design, Human–Robot Interaction, and Clinical Translation

Yonggen Zhao, Yeming Zhang, Maolin Cai, Feng Wei

Upper-limb motor dysfunction resulting from neurological disorders severely limits patients’ activities of daily living and social participation. Pneumatic upper-limb rehabilitation robots have emerged as a promising intervention owing to their inherent compliance, lightweight design, and high power-to-weight ratio, which facilitate safe, repetitive, and home-based training. Despite these advantages, extensive clinical translation remains hindered by challenges including actuator hysteresis, nonlinear dynamics, lim …

14.08.2026journal-article

Pharmaceutics

Bergapten as a Multifunctional Phytochemical in Cancer Therapy: Mechanistic Insights, Pharmacokinetics, and Possible Nanotechnology-Enabled Formulation Strategies

Victória Dogani Rodrigues, Maria Angélica Miglino, Claúdia Rucco Penteado Detregiachi, Sandra Maria Barbalho, Lucas Fornari Laurindo

Bergapten is a plant-derived linear furanocoumarin widely distributed in Rutaceae and Apiaceae species and increasingly recognized for its multifunctional anticancer potential. This review critically synthesizes current evidence on bergapten’s biosynthesis, physicochemical and pharmacokinetic properties, anti-inflammatory and antioxidant pharmacodynamics, and mechanistic antitumor activity, highlighting its translational relevance within pharmaceutical development. Preclinical studies across diverse malignancies de …

14.08.2026journal-article

Advances in Translational Research

Novel biomarkers in breast cancer for precision therapy and adaptive treatment strategies

Dao-Fu Dai, Tamas Micsik

Abstract Breast cancer is a biologically heterogeneous disease in which clinical outcomes are strongly influenced by molecular characteristics that guide therapeutic decision-making. While the traditional framework based on estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) has enabled major advances in patient stratification, it provides only a limited and static representation of tumor biology. Increasing evidence indicates that breast cancer evolves dynamicall …

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14.08.2026journal-article

Gynecology and Minimally Invasive Therapy

Complication Spectrum of Hysterectomy: A Retrospective Cohort Study from a Tertiary Care Hospital

Arun Sanap, Neha Gangane, Medha Davile, Anusha Kamath, Shuchita Mundle, Anita Yadav

Abstract Objectives: The objective of this study was to investigate the complications of hysterectomy. Materials and Methods: This retrospective cohort study was conducted at Tertiary Care Hospital and Institute of National Importance in Central India, including 310 patients, to analyze the complications associated with the hysterectomy. Medical records were obtained, and the demographic details, associated co-morbidities, surgical details, including indication, timing, and route of hysterectomy, were noted. Intrao …

14.08.2026journal-article

CAMPO JURÍDICO

ANTIMICROBIAL RESISTANCE IN INTENSIVE CARE: CURRENT CHALLENGES AND FUTURE PERSPECTIVES ON COMBINATION ANTIMICROBIAL THERAPY

Dianah Dantas Pulvirenti, João Pedro Zanatto, Ana Carolina Fontana Bolsoni, José Gabriel Cavalcanti Garcia, Maria Júlia Daniel Peixoto, Edna Pereira da Silva, Arthur Menegucci Vicenconi, Bruna Gonçalves Manzoni, Lucileia Mazuqueli Marques, Mirella Cristina Mazuqueli Marques, Fabiana Campos Castro de Carvalho, Rodolfo de Oliveira Medeiros

Antimicrobial resistance represents one of the greatest contemporary challenges in intensive care medicine, being associated with increased mortality, prolonged hospital stays, higher healthcare costs, and reduced therapeutic options. Critically ill patients are particularly susceptible to the development and dissemination of multidrug-resistant microorganisms due to disease severity, frequent exposure to invasive devices, prolonged antimicrobial use, and immune dysregulation associated with critical illness. In th …

14.08.2026journal-article

Nutrients

Medical Nutrition Therapy with Meal Sequence and Divided Carbohydrate Intake: Associations with Ketonuria Resolution and Neonatal Outcomes in Gestational Diabetes Mellitus

Saeko Imai, Shizuo Kajiyama, Yuki Higuchi, Shintaro Kajiyama, Yoshitaka Hashimoto, Michiaki Fukui

Background/Objectives: Ketonuria is frequently observed in women with gestational diabetes mellitus (GDM), particularly when energy and carbohydrate intake is inadequate. This retrospective study evaluated nutritional status and neonatal outcomes following dietitian-led medical nutrition therapy (MNT) in 517 Japanese women with GDM with and without ketonuria. Methods: Dietary counseling emphasized a meal sequence in which vegetables were consumed before protein-rich foods and carbohydrates were consumed last, toget …

14.08.2026journal-article

RSV

Care Management for Neurological Sequelae in Brazil's Unified Health System: Strategies for Comprehensive Rehabilitation

Juliana Aparecida Pereira Ribeiro, Gabriela Eiras Ortoni, Mônica Rodrigues da Silva, Wenderson Gonçalves Andrade, Janayna de Oliveira Silva, Mônica Alessandra Dias Rocha, Regina Gabriela Caldas de Moraes, Oldair Donizete Galeni

Neurological sequelae resulting from stroke, traumatic brain injury, spinal cord injury, neurodegenerative disorders, and other neurological conditions have become a major challenge for healthcare systems due to their long-term impact on functionality, autonomy, and quality of life. In Brazil's Unified Health System (SUS), comprehensive rehabilitation requires coordinated care management capable of integrating different levels of healthcare while ensuring continuity, equity, and patient-centered interventions. This …

14.08.2026journal-article

Journal of Clinical Medicine

Hematological Toxicities in the Modern Era of Melanoma Therapy

Rodica Anghel, Ana-Maria Zamfirescu-Deryder, Vlad-Luca Moga, Antonia-Ruxandra Folea, Radu-Valeriu Toma, Andreea-Iren Șerban, Liviu Bîlteanu

Background/Objectives: The advent of immune checkpoint inhibitors (ICIs) and targeted therapies has revolutionized advanced melanoma treatment but introduced unique immune-related adverse events (irAEs). Hematological irAEs (Hem-irAEs) are rare but carry disproportionately high morbidity and mortality. This review systematically synthesizes current literature to comprehensively understand the incidence, pathophysiology, clinical presentation, and management of Hem-irAEs in modern melanoma therapy. Methods: A compre …

14.08.2026journal-article

Traumatology and Orthopedics of Russia

EFFICACY AND SAFETY OF VARIOUS ORAL ANTIBACTERIAL THERAPY REGIMENS FOR IMPLANT-ASSOCIATED INFECTION CAUSED BY LEADING GRAM-NEGATIVE PATHOGENS

Olga S. Tufanova, Svetlana A. Bozhkova, Ekaterina M. Gordina, Alexander P. Antipov

Background. The high level of antibacterial resistance of the leading gram-negative pathogens of orthopedic infection leads to difficulties in selecting antibacterial drugs at both in patient and out patient treatment stages. Does the antibiotic resistance of Gram(-) bacteria isolated from patients to oral antibiotics affect the effectiveness of treatment? Is it necessary to prescribe oral AB drugs to patients who have isolated a pathogen resistant to them? Are there differences in the efficacy and safety of using …

14.08.2026journal-article

Pharmaceutics

Machine Learning for Valproic Acid Therapy: A Scoping Review of Pharmacokinetic-Prediction Models and Pharmacokinetic-Informed Clinical Outcome Models

Janthima Methaneethorn, Supavadee Aramvith, Wanaporn Charoenchokthavee, Sohaib Habiballah, Khanita Duangchaemkarn, Brad Reisfeld

Background/Objectives: Population pharmacokinetics (PopPK) has been used to aid valproic acid (VPA) dose individualization. However, this approach faces limitations owing to the complexity and high dimensionality of datasets. Machine learning (ML) can handle these challenges. However, the comparative evaluation of these ML algorithms and their practical application in optimizing VPA therapy have not yet been established. This review aims to summarize the current evidence, identify research gaps, and outline ML appl …

14.08.2026journal-article

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology

Quality of Life Outcomes in Patients with Pulmonary Hypertension Receiving Prostacyclin Therapy: Impact of Anxiety, Depression, Sociodemographic Characteristics, and Treatment-Related Factors

Fatma Yıldırım, Elif Ok, Vesile Ünver, Dilek Sezgin, Halil Ataş, Betül Şentürk Saraç

Objective: Despite advances in prostacyclin therapy, pulmonary hypertension (PH) continues to impair patients' quality of life (QoL). This study aimed to identify the clinical and psychological factors associated with QoL in patients receiving prostacyclin therapy. Method: This cross-sectional study was conducted between July 2023 and September 2024 and included 58 patients with PH receiving prostacyclin therapy. Data were collected using a structured questionnaire assessing sociodemographic and disease-related cha …

14.08.2026journal-article

Pilot and Feasibility Studies

Protocol for a feasibility study of a self-help resource based on the principles of cognitive behavioural therapy to reduce needle fear in young people aged 11- to 16 years

Fiona Sotir, David White, Gemma Wheeler, Helen Rodd, Zoe Marshman

Abstract Background Needle fear affects up to half of all young people, with the potential to impede their accessing and acceptance of healthcare interventions. There is presently a lack of accessible self-help resources available to support young people in managing needle-based procedures. This feasibility study aims to create a trial protocol for future definitive assessment of a self-help tool co-designed with young people, to manage their fear of needles. Methods This article presents the protocol for a study t …