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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
15.08.2026journal-article

Cardiovascular Therapy and Prevention

Myocardial remodeling in elderly women with heart failure with preserved ejection fraction: association with a burdened obstetric history

M. V. Kosulina, M. I. Shperling, A. A. Ivanova, E. A. Rogozhkina, O. N. Dzhioeva, O. M. Drapkina

Aim. To evaluate structural and functional cardiac parameters in elderly women with heart failure with preserved ejection fraction (HFpEF) in association with unfavorable pregnancy factors and outcomes in history. Material and methods . This cross-sectional study included 80 women aged 60-74 years with HFpEF and a history of pregnancy. All patients underwent echocardiography to assess the structural and functional parameters of the left heart. Obstetric history was collected using a standardized interview. Results. …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

Efficacy of human immunoglobulin for overcoming interleukin-1 inhibitor dependence in patients with chronic and recurrent pericarditis

Z. N. Sukmarova, A. S. Starkova, N. L. Bondarenko

Aim . Practical data indicating the optimal adjuvant therapy strategy for preventing and overcoming interleukin-1 inhibitor (IL-1I) dependence are lacking. Therefore, we evaluated the efficacy of intravenous immunoglobulin (IVIG) in patients with chronic (CP) and recurrent pericarditis (RP) during the discontinuation of IL-1I (anakinra). Material and methods. The follow-up group included patients with chronic pancreatitis and recurrent pancreatitis who received anakinra 100 mg for >6 months. For 2 months, in parall …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

Effect of transcutaneous vagus nerve stimulation on reducing the recurrence risk in patients with paroxysmal atrial fibrillation after pulmonary vein cryoablation

E. M. Sizhazhev, V. A. Shvarts, V. V. Antonyan, S. A. Donakanyan

Aim. To evaluate the efficacy and safety of long-term (6 months) transcutaneous vagus nerve stimulation (tVNS) in reducing the risk of atrial fibrillation (AF) recurrence and improving quality of life (QOL) in patients after catheter cryoablation. Material and methods . This randomized, double-blind, sham-controlled study was conducted. Patients with paroxysmal AF after cryoablation (n=42) were randomized into two following groups: an active group (n=20) receiving tVNS, and a sham-control group (n=21) using sham pa …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

First experience of applying a new staging classification of heart failure in real-world practice (based on an interim analysis of the HOSTA-CHF registry study data)

F. T. Ageev, O. N. Svirida, Z. N. Blankova, N. V. Lazareva, V. Yu. Mareev, A. G. Ovchinnikov, F. N. Paleev, A. V. Pustelenin, E. V. Sorokin, E. M. Filichkina, E. G. Chernyshenko, A. M. Shangina, E. B. Yarovaya, S. A. Boytsov

Aim . To evaluate and compare the application and interpretation of heart failure stages by physicians based on the criteria of the previous and new classifications of heart failure (HF). Material and methods . In October 2024, the new guidelines of the Russian Ministry of Health on HF, with revised classifications of HF stages, came into effect. It is unknown how accurately physicians apply the changes in the HF staging classification in practice. Data on diagnoses of 13902 patients with HF from the interregional …

15.08.2026journal-article

Advanced Healthcare Materials

Decoration of Porous TiO 2 Implants With Metal‐Organic Composites Enables Synergistic Therapy for Osteoporotic Fracture Healing

Xinyi Huang, Shaoyin Wei, Zhenqian Sun, Xiang Li, Huanyu Liu, Lin Han, Yunyun Feng, Zongwang Yang, Jinglin Lu, Yixuan Li, Jiwei Cui, Jie Guo, Chao Liu

ABSTRACT Osteoporotic fracture healing is trapped in a vicious cycle where multiple pathological factors, including persistent oxidative stress, inadequate vascular supply, and an imbalance bone remodeling process that favors resorption, combine to form a hostile niche for regeneration. The intricate interaction of these pathologies highlights the need to transform titanium implants from inert devices into active platforms for bone regeneration. In this study, a multifunctional coating where titanium dioxide nanotu …

15.08.2026journal-article

Journal of Health Science and Medical Therapy

Relationship between Toxoplasma Gondii Infection and Neurological Disorders: A Systematic Review

Rolando Sánchez Artigas, Ariagna Martínez Pérez, Yoiler Batista Garcet, Leonardo Vera Viteri

Toxoplasma gondii infection has traditionally been considered a zoonosis with an asymptomatic course; however, recent research has suggested its involvement in various neurological and neuropsychiatric disorders. The aim of this study was to analyze the relationship between toxoplasmosis and alterations of the human nervous system through a systematic review of the scientific literature. A structured search was conducted in biomedical databases (PubMed, Scopus, SciELO, RedALyC, Google Scholar) using key descriptors …

15.08.2026journal-article

Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)

The Family and Health Workers Support Role to Undergo Triple Elimination Screening in Pregnant Women based on The Health Belief Model Perspevtive

Erika, Iskandar Muda

Triple Elimination testing is an important strategy to prevent the transmission of HIV, syphilis, and hepatitis B from mother to child. However, currently the coverage of check-ups for pregnant women is still not optimal. This study aimed to explore the role of family and health worker’s support in strengthening pregnant women's decisions to undergo Triple Elimination tests based on Health Belief Model perspective. This study used a qualitative design with a descriptive approach. Seven pregnant mothers were selecte …

15.08.2026journal-article

Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)

Reducing Blood Pressure and SRAS Scores in Preoperative CDL Patients Through Alternate Nostril Breathing Exercise (ANBE)

Asni Hasaini, Muhlisoh

Patients diagnosed with CKD often experience changes in both physiological and psychological responses. Alternate Nostril Breathing Exercise (ANBE) has been reported to influence cardiorespiratory and autonomic functions, as well as to reduce anxiety and stress scores. The objective of the study was to analyze the effectiveness of ANBE on the stability of physiological and psychological responses in preoperative patients undergoing CDL insertion at Ratu Zalecha Hospital, Martapura. The study employed a quasi-experi …

15.08.2026journal-article

Genetics and Molecular Research

EFFECTIVENESS OF MICRONIZED PURIFIED FLAVONOID FRACTION AS ADJUNCTIVE THERAPY IN PATIENTS WITH VARICOSE VEINS: A PROSPECTIVE OBSERVATIONAL STUDY

Jalpa Suthar, Shruti Upadhyay

Varicose veins are a common manifestation of chronic venous disease (CVD) and are associated with symptoms such as pain, edema, heaviness, and impaired quality of life (QoL). Micronized purified flavonoid fraction (MPFF), a venoactive agent composed primarily of diosmin and hesperidin, has been widely used for symptomatic management of CVD because of its venotonic, anti-inflammatory, and microcirculatory effects. Objective: To evaluate the prescribing patterns, clinical outcomes, and safety of MPFF in patients with …

15.08.2026journal-article

Pharmacogenetics and Pharmacogenomics

Pharmacogenetics and mathematical modeling: approaches to individual prediction of response to ACE inhibitor therapy

O. V. Komarova, B. I. Kantemirova, A. N. Romanova, O. V. Petrova

Background. The therapeutic response to ACE inhibitors in hypertension is variable and depends on a combination of clinical, behavioral, and pharmacogenetic factors. Mathematical modeling allows us to assess their contribution to achieving the target values of blood pressure. Objective. To determine the factors associated with the achievement and non-achievement of target blood pressure values in patients with arterial hypertension receiving ACE inhibitors in monotherapy. Materials and methods. A single-center obse …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

A comparative analysis of hypertension in men living in Novosibirsk and rural areas of the Novosibirsk Oblast

M. A. Ismailova, A. D. Afanasyeva, E. V. Garbuzova, V. S. Shramko, G. I. Simonova, O. N. Gerasimenko, L. A. Shpagina, O. V. Dunicheva, A. E. Imaeva, Yu. A. Balanova, Yu. I. Ragino

Aim . To compare the main risk factors for hypertension (HTN), its incidence, treatment coverage, treatment patterns, and blood pressure (BP) control among men living in Novosibirsk and rural areas of the Novosibirsk Oblast. Material and methods . The study included 900 men aged 35-74 years registered at the Novosibirsk outpatient clinics and central district hospitals in the Ordynsky and Kochenevsky districts of the Novosibirsk Oblast. Hypertension was considered diagnosed if systolic BP exceeded 140 mm Hg and/or …

15.08.2026journal-article

Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)

Risk Factors of Sexual Behavior Related to Sexually Transmitted Infections among Male Adolescents in Sidoarjo Regency

Iryani Yuni Yastutik, Ani Margawati, Zahroh Shaluhiyah, Ayun Sriatmi

Risky sexual behavior among male adolescents contributes substantially to the increasing incidence of sexually transmitted infections (STIs). Understanding the associated determinants is essential for developing effective prevention strategies. This study analyzed factors associated with risky sexual behavior related to STIs among male adolescents in Sidoarjo Regency. An analytical cross-sectional study was conducted among the population of 10,980 and took 9,160 male adolescents aged 15–24 years in Sidoarjo Regency …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

Model for estimating the fatal outcome probability after coronary artery bypass grafting

I. A. Ulyanov, N. I. Ostroushko, S. A. Kovalev, N. E. Nekhaenko, Yu. A. Sharapova

Aim. To develop a model for assessing the fatal outcome probability after coronary artery bypass grafting (CABG) based on comprehensive preoperative patient characteristics. Material and methods . The model of fatal outcome-associated factors after CABG was developed using medical records from 1584 patients who underwent isolated CABG between 2021 and 2024. Twenty-four preoperative patient characteristics were selected, from which factors associated with fatal outcome were identified. The study endpoint was death d …

15.08.2026journal-article

Journal of Medicine and Palliative Care

Emotional responses and practice characteristics of speech and language therapists on delivering bad news in Turkiye

Beril Ayran, Nazmiye Evra Günhan Şenol

Aims: This study aimed to examine the emotional experiences, and practice characteristics of speech and language therapists (SLTs) in Turkiye regarding the delivery of bad news.Methods: A descriptive cross-sectional design was used. Data were collected through an online questionnaire completed voluntarily by 113 SLTs who had experience delivering bad news to clients and/or their families. The questionnaire addressed participants’ demographic and professional characteristics, communication practices, emotional respo …

15.08.2026journal-article

Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)

Intention-Based Transcultural Family Empowerment Model for Complementary Feeding Practices: A Structural Equation Modeling Approach

Agusta Dian Ellina, Novian Mahayu Adiutama, Yudisa Diaz Lutfi Sandi, Wardah Fauziah, Dewi Rahayu Ningsih, Esti Andarini, Sandi Alfa Wiga Arsa, Nuridha Fauziyah

Stunting remains a major public health concern in Indonesia, particularly among children aged 6–24 months. The quality of complementary feeding is strongly influenced by cultural norms and family dynamics. This study aimed to validate a previously developed transcultural care-based family empowerment model by integrating “intention” as a mediating factor in behavioral change. A cross-sectional study was conducted involving 530 families in Kediri, East Java, Indonesia. Data were collected using structured questionna …

15.08.2026journal-article

The Journal of Rheumatology

Multi-target Therapy with Rituximab plus Mycophenolate Mofetil versus Rituximab Monotherapy in Systemic Sclerosis–Associated Interstitial Lung Disease

Rudra P. Goswami, Vamshikrishna Patel Kotha, Manupati Surya

Objective To compare the effectiveness and safety of rituximab (RTX) plus mycophenolate mofetil (MMF) versus RTX monotherapy in patients with SSc-ILD. Methods We performed a retrospective comparative analysis among adults with radiologically confirmed SSc–ILD treated with rituximab monotherapy or RTX + MMF (MTT) as rituximab-based treatment strategy. The primary outcome was improvement in percent-predicted forced vital capacity (FVC%) of more than 5 percentage points at the end of 2 nd year (ΔFVC>+5). Secondary out …

15.08.2026journal-article

International journal of health sciences

Comprehensive midwifery care for Mrs. “R” G2P1A0 in the independent practice of midwife Desi Fitriani, SKM., S.Keb

Indrawati Indrawati

One of the government's efforts to reduce MMR and IMR in Indonesia is the provision of continuous care or Continuity Of Care (COC) to supervise, care and management of pregnant women, childbirth, newborns, postpartum and family planning. The aim is to provide midwifery care to Mrs. "R" at TPMB Desi Fitriani, SKM., S.Keb during pregnancy, childbirth, postpartum, and neonates using a midwifery care management approach. The research method used is a descriptive observational method with a case study approach. The time …

15.08.2026journal-article

Pedagogy and Psychology of Sport

The Axiological Potential of Sport as a Means of Rehabilitation and National Identity in Wartime: A Comprehensive Review

Olena Kuznietsova

Background. The main problems of axiology and communication in sports are focused on the transformation of moral values, adaptation to the challenges of martial law and the transition to transparent business communications and the club system. The problem of interaction between state executive bodies and public associations and the population of the region remains poorly studied in the scientific literature, in addition, a systematic review does not synthesize the results of all aspects of sport as an important pla …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

Intravascular ultrasound-guided renal artery stenting without the use of radiocontrast agents

I. A. Aboyan, Y. V. Kulikovskikh, N. V. Kalaitanova, R. H. Mkrtchyan, D. S. Luzhanskyi, D. V. Lavnik, D. S. Strokov, L. G. Oganesyan, M. Z. Gasanov

Aim . To analyze immediate and in-hospital outcomes of intravascular ultrasound (IVUS)-guided renal artery (RA) stenting without the use of radiocontrast agents in patients with chronic kidney disease (CKD) and renovascular hypertension. Material and methods . This prospective single-center study included 26 patients with CKD stage C3a-C5 and hemodynamically significant RA stenosis based on triplex ultrasound imaging. The patient age (median [min-max]) was 63 [48-76] years; 61,5% were women. Before the procedure, t …

15.08.2026journal-article

Russian Journal of Cardiology

Platelet-to-hemoglobin ratio (PHR) as a prognostic marker of thrombotic events and inhospital mortality in cardiovascular diseases and potential for its use in patients on antithrombotic therapy: a literature review

S. S. Postnikov, N. V. Teplova, O. V. Gulbekova, G. R. Zaripova

Platelet-to-hemoglobin ratio (PHR = platelets ×10 9 /L/hemoglobin g/L) is a laboratory marker proposed in 2019-2020 that combines prothrombotic potential and anemia grade in a single indicator. The aim of this study is to systematize existing data on the pathophysiological basis, calculation methodology, and prognostic value of PHR for adverse cardiovascular outcomes and in-hospital mortality. In addition, we assessed its potential in thrombotic and bleeding risk stratification in patients receiving antithrombotic …

15.08.2026journal-article

International Medical Education

An Exploratory Pilot Evaluation of a Blended Virtual Reality and Mannequin-Based Educational Program for Teaching the Initial Management of Postpartum Hemorrhage to Midwifery Students

Yumika Tachikawa, Kenya Kamimura, Tomoko Sumiyoshi, Mayumi Nishikata, Mayumi Ishida, Chiho Morita, Sayaka Kojima, Mieko Uchiyama

Background/Objectives: Opportunities for pre-service midwifery students to manage postpartum hemorrhage (PPH), a high-risk, infrequent emergency, are limited. Virtual reality (VR) can provide contextual decision-making practice, whereas mannequin training provides tactile psychomotor practice. Evidence on combining these modalities and their instructional sequence remains limited. This exploratory pilot study examined implementation and preliminary outcomes of a blended lecture–VR–mannequin program. Methods: Ten fi …

15.08.2026journal-article

Journal on Audio, Speech, and Music Processing

Attention-based time–frequency aggregated tokens for sound event classification in basketball game

Yunhao Zhao, Lifang Wu, Zeyu Xi, Haoying Sun, Yue Yao

Abstract With the rapid advancement of computer technology, its application in basketball game analysis has become a prominent research focus. Sound events in basketball games encapsulate critical game-related information. However, research on sound event classification in basketball games remains in its early stages. This research systematically analyzes the sound events in basketball games, and constructs an open-source dataset of sound events in basketball games, which is characterized by larger scale and more d …

15.08.2026journal-article

Société Internationale d’Urologie Journal

Empirical Oral Antibiotic Therapy Is Associated with Reduced Sperm DNA Fragmentation in Infertile Men: A Retrospective Paired Pre- and Post-Intervention Study

Moises Abraham Adel Domínguez, Walter D. Cardona Maya, Andrés Mora Topete

Background/Objectives: This study aims to assess changes in seminal parameters and sperm DNA fragmentation (SDF) index after empirical oral antibiotic therapy in infertile men with baseline SDF index > 15%. Methods: This retrospective, paired, uncontrolled pre- and post-intervention study included 98 infertile men with elevated baseline SDF index. Semen samples were obtained before treatment and at least two months after simultaneous oral treatment with ciprofloxacin 1000 mg/day for 21 days and doxycycline 100 mg/d …