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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
15.08.2026journal-article

Actas Españolas de Psiquiatría

Research Progress on Light Therapy to Improve Depressive Symptoms of Bipolar Depression

Yutong Cui

Bipolar depression is the predominant and most disabling phase of bipolar disorder, featured by recurrent depressive episodes that impair psychosocial function and quality of life. Conventional pharmacotherapy has limited efficacy and carries a risk of mood destabilization (e.g., affective switch). Light therapy, a nonpharmacological chronotherapeutic intervention, has shown potential to improve bipolar depression symptoms by regulating circadian rhythms and mood regulating neural circuits. This review synthesized …

15.08.2026journal-article

American Journal of Human Psychology

Influence of Solution-Focused Therapy (SFT) in Inculcating Passion and Dedication to Counseling in Guidance Counselors in Imo State

Francisca Ngozi Okoro

This study examined the perceived influence of Solution-Focused Therapy (SFT) on passion and dedication to counseling among guidance counselors in Imo State. A descriptive survey design was adopted, involving 107 guidance counselors selected through purposive sampling. Data were collected using a structured online questionnaire and analyzed using descriptive statistics (mean and standard deviation). Findings revealed that counselors perceived SFT as having a strong influence on their passion (M = 4.02) and dedicati …

15.08.2026journal-article

Journal of Dementia and Alzheimer's Disease

Fluid and Imaging Biomarkers in Lecanemab Therapy for Early Alzheimer’s Disease: Current Evidence, ARIA Risk Prediction, and Treatment Monitoring

Pan-Woo Ko

Background/Objectives: Lecanemab, a humanized anti-amyloid-β protofibril antibody, achieves substantial amyloid clearance and modest slowing of clinical decline in early Alzheimer’s disease (AD). Amyloid-related imaging abnormalities (ARIA) represent the most clinically important safety concern, yet no fluid biomarker has been prospectively validated for ARIA prediction in lecanemab-treated patients. This review critically synthesizes current evidence on fluid and imaging biomarkers for ARIA risk stratification and …

15.08.2026journal-article

Advanced Healthcare Materials

Algae‐Integrated Optoelectronic Nanoplatform for Tumor Hypoxia Relief and Enhanced Photodynamic Therapy

Gongcheng Ma, Nan Zhang, Hongrong Shi, Yaoqiang Li, Haoran Wang, Chaoyang Tang, Shengmei Wang, Hongli Chen, Qingzhi Wang, Zhaohui Wang, Guogang Liu, Ben Zhong Tang, Qihang Ding

ABSTRACT The clinical efficacy of photodynamic therapy (PDT) is fundamentally limited by the scarcity of efficient photosensitizers (PSs) and the oxygen dependence of singlet‐oxygen–mediated cytotoxicity. Here we report pentaperylene decaimide selenide (PPD‐Se), a nanographene‐derived photoelectronic material that functions as a high‐performance Type‐II photosensitizer. PPD‐Se exhibits broadband absorption (300–650 nm), enhanced intersystem crossing enabled by a selenium‐induced heavy‐atom effect, a small ΔE ST (0. …

15.08.2026journal-article

Actas Españolas de Psiquiatría

Effect of Mobile Application-Based Cognitive Behavioural Therapy on Atopic Dermatitis Comorbid With Obsessive-Compulsive Disorder: A Retrospective Study

Dan Liang, Lihong Yang, Xian He

Background: This study aimed to evaluate the effect of mobile application-based cognitive behavioural therapy (MCBT) in patients with atopic dermatitis (AD) and comorbid obsessive-compulsive disorder (OCD). Methods: This retrospective study analysed 100 patients with AD and comorbid OCD treated at Chengdu First People’s Hospital from January 2024 to December 2025. Patients were divided into an MCBT group (n = 50) and a conventional group (n = 50) according to the treatment they received. All patients received routi …

15.08.2026journal-article

BMC Oral Health

Dentoalveolar and skeletal changes after customized elastodontic appliance therapy in mixed dentition children with maxillary transverse deficiency: a retrospective CBCT study

Jianhua Li, Xinran Fan, Qingyu Wang

Abstract Background This exploratory study aimed to evaluate the expansion effects of a customized elastodontic appliance (CEA) on maxillary and mandibular arches in mixed dentition children using cone-beam computed tomography (CBCT), and to clarify whether these effects are dental, dentoalveolar, or skeletal. Methods This retrospective study included 31 mixed dentition children (mean age 8.3 ± 1.2 years) who underwent CEA treatment for 8.2 ± 1.3 months. Pre- and post-treatment CBCT images were used to measure widt …

15.08.2026journal-article

Actas Españolas de Psiquiatría

Effects of Emotion-Focused Therapy on Weight Restoration and Emotion Regulation in Adolescents With Anorexia Nervosa

Linfeng Liu, Nongmei Cheng, Qing Feng

Background: To investigate the effects of emotionfocused therapy (EFT) on weight restoration and emotion regulation in adolescents with anorexia nervosa (AN). Methods: This retrospective study included 188 adolescents with AN treated at Chongqing Mental Health Center between January 2023 and December 2025. According to treatment methods, patients were divided into a control group and an EFT group. After screening based on inclusion and exclusion criteria, 60 patients in each group were included in the final analysi …

15.08.2026journal-article

JOEY: Journal of English Ibrahimy

The The Role of Drama in Improving Students' comprehension of Reported Speech

Rawend Sitorus, Chairuddin, Baihaqi

This study aims to examine the role of drama scripts implemented through role-play activities in improving students’ comprehension of reported speech at SMK Negeri 2 Langsa. This research employed a quantitative approach using a one-group pre-test and post-test design. The population of this study consisted of all eleventh-grade students of SMK Negeri 2 Langsa, while the sample was class XI RPL comprising 25 students selected through purposive sampling. The instrument used to collect the data was a grammar test in …

15.08.2026journal-article

Cancers

Exploring the Impact of T2-Weighted MRI Fat Saturation on Radiomics Stability for Brain Radionecrosis Prediction After Skull-Base Proton Therapy: A Pilot Study

Sithin Thulasi Seetha, Giulia Fontana, Sara Imparato, Sara Lillo, Lucia Pia Ciccone, Marina Francesca Achilli, Chiara Paganelli, Silvia Molinelli, Alberto Iannalfi, Guido Baroni, Lorenzo Preda, Ester Orlandi

Background/Objectives: In skull-base proton therapy, T2-weighted brain magnetic resonance (MR) imaging may be acquired with or without fat saturation (FS). The present study investigated the impact of this protocol variation on radiomics feature stability and brain radionecrosis (BRN) prediction. Methods: Paired T2-weighted FS and non-FS follow-up MR scans of proton-treated skull-base chordoma patients (n = 52) were used to assess feature stability. For BRN prediction (CTCAEv5 grade ≥ 1), baseline planning scans of …

15.08.2026journal-article

Stem Cell Research & Therapy

Stem cell–based therapies in pediatric disorders: translational advances, unresolved challenges, and future horizons

Hany E. Marei

Abstract Pediatric disorders consist of genetic, hematologic, neurologic, autoimmune, and inflammatory diseases. These conditions impose long-term health challenges on children, despite many advancements with conventional medicine. Although conventional treatments increase life expectancy and provide better disease control, many present challenges such as toxicity, insufficient control of the disease, and adverse effects on normal growth, development, and quality of life. Many researchers have shown increased inter …

15.08.2026journal-article

International Journal of Digital Rehabilitation & Therapy

Syndrome Diagnosis in Traditional Chinese Medicine: Meridians, Eight Extraordinary Vessels and Five Element Theory

İpek Nurdan Dikmen, Dilek Öztaş, Salih Mollahaliloğlu

Syndrome diagnosis in Traditional Chinese Medicine (TCM) holistically evaluates functional and energetic imbalances in the body. This review aims to examine the fundamental principles of syndrome diagnosis in TCM by integrating meridian theory, the eight extraordinary vessels, and the five-element theory within a holistic diagnostic framework. The conceptual and theoretical foundations of syndrome diagnosis were examined by focusing on the functions of the meridian system, the regulatory roles of the eight extraord …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

Oxidative stress severity and mitochondrial DNA polymorphisms in patients with heart failure at high risk of sudden cardiac death

T. Yu. Rebrova, V. A. Korepanov, M. V. Golubenko, E. F. Muslimova, T. A. Atabekov, S. V. Popov, S. S. Dorzhieva, A. A. Utusikova, S. A. Afanasyev

Aim. To assess the severity of oxidative stress and the presence of polymorphic variants of mitochondrial deoxyribonucleic acid (mtDNA) in patients with heart failure (HF) and a high risk of sudden cardiac death (SCD). Material and methods . The study included 198 patients (78,79% men) diagnosed with HF and implantable cardioverter-defibrillators (ICDs) for the prevention of life-threatening ventricular tachycardia (VT) and SCD. The control group consisted of 28 healthy volunteers (men, 64,29%). Clinical and paracl …

15.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Small-sided games in floorball: impact on technical actions in players aged 7–18

Mårten Storm, Taru Tervo, Jonas L. Markström

Abstract Background Small-sided games (SSGs; modified match play with fewer players and a smaller pitch) are widely used in team sports to develop adaptable movement skills and decision-making in game-like contexts. However, evidence is limited on how different SSG formats affect technical actions in youth floorball. This study examined how different SSG formats influence technical actions by outfield players in floorball, and whether these effects differ by age group and biological sex. Methods Twenty-four youth f …

15.08.2026journal-article

Cardiovascular Therapy and Prevention

Coronary Artery Ectasia prevalence and factors associated with ectasia in patients undergoing coronary angiography: An observational comparison analytic study

Hayder Abdulateef Zghair Nassir, Ahmed Qasim Ibrahim Mohammed, Hassan Abdulrazzaq Swaid

Aim . To determine the prevalence and risk factors of coronary artery ectasia (CAE), as well as the distribution of ectasia among the coronary vessels. Material and methods . An observational comparison analytic study was conducted in two cardiac centers in Iraq from February 2020 to February 2021, involving 263 patients who underwent coronary angiography. Clinical data and cardiovascular factors were analyzed to identify associations with CAE using logistic regression. Results . CAE was detected in 14.8% of the pa …

15.08.2026journal-article

Tạp chí Y học Dự phòng

Thực trạng căng thẳng nghề nghiệp của điều dưỡng tại các cơ sở y tế giai đoạn 2015-2025: Tổng quan luận điểm

Thị Thu Hà Nguyễn, Nguyễn Thị Mỹ Duyên, Nguyễn Thị Thu Hà, Phạm Diệu Linh

Căng thẳng nghề nghiệp ở điều dưỡng là một thách thức phổ biến trong bối cảnh môi trường y tế ngàycàng phức tạp. Nghiên cứu này nhằm mô tả thực trạng và nhận diện một số yếu tố liên quan đến căngthẳng nghề nghiệp của điều dưỡng trong giai đoạn 2015–2025. Nghiên cứu được thực hiện theo phươngpháp tổng quan luận điểm, thông qua rà soát và sàng lọc các tài liệu xuất bản từ năm 2015 đến năm 2025trên các cơ sở dữ liệu lớn, gồm PubMed, Cochrane Library, ScienceDirect, Google Scholar và hệ thốngdữ liệu y khoa Việt Nam. Kế …

15.08.2026journal-article

Actas Españolas de Psiquiatría

Effectiveness of Digital Cognitive Behavioural Therapy (dCBT) for Co-Occurring Anxiety, Depression and Chronic Pain in Adults: A Systematic Review and Meta-Analysis

Li Zhu, Yanping Ji, Juner Le, Henan Wu

Background: This study aimed to evaluate the effectiveness of digital cognitive behavioural therapy (dCBT) in reducing pain intensity, pain interference, depression, and anxiety symptoms in adults with co-occurring chronic pain, anxiety and depression. Methods: We systematically searched in PubMed, PsycINFO, Cochrane Library and Web of Science for randomized controlled trials (RCTs) published up to October 2025. Included studies comparing dCBT with control conditions in adults with chronic pain (≥3 months), co-occu …

15.08.2026journal-article

Revista ft

Burnout e qualidade de vida na enfermagem oncológica: desafios para a saúde do trabalhador e para a assistência humanizada

Josefa Maria Oliveira Xavier, Neidejane Trajano do Nascimento, Rosilene Vila Nova Feliciano, Aurinéa Santos da Rocha, Avanize Maria Gomes, Solange Matilde Cordeiro de Souza, Wedja da Silva Lima

Oncology nursing is characterized by high technical and emotional complexity, involving specialized care, continuous monitoring, and frequent exposure to suffering, pain, therapeutic uncertainty, and end-of-life situations. These characteristics may contribute to the development of Burnout Syndrome and negatively affect professionals' quality of life. This study aimed to analyze the available scientific evidence on Burnout and quality of life among nursing professionals working in oncology services. This is an inte …

15.08.2026journal-article

World Journal of Gastrointestinal Oncology

Association of claudin 18.2 expression with outcomes of ramucirumab plus paclitaxel as second-line therapy in advanced gastric cancer

Mi-Ran Han, Ji Eun Shin, Sung Hee Lim, Jeeyun Lee, Seung Tae Kim

BACKGROUND Ramucirumab plus paclitaxel remains the standard second-line treatment for advanced gastric cancer (AGC), despite evolving frontline therapies. However, the prognostic and predictive significance of claudin 18.2 (CLDN18.2) expression in this setting remains unclear. AIM To evaluate the prognostic and predictive significance of CLDN18.2 expression in patients with AGC treated with ramucirumab plus paclitaxel. METHODS This retrospective study included patients with AGC who underwent treatment with ramuciru …

15.08.2026journal-article

International Journal of Ayurveda360

Management of Recurrent Fistula-in-Ano with Apamarga Ksharsutra Therapy: An Ayurvedic Case Report

Dilip Parmar, Dhimant V. Bhatt, Prashant R. Madane

Background: Fistula-in-ano is a chronic anorectal condition with a high risk of recurrence after conventional surgical procedures. Ayurveda describes this condition as Bhagandara, categorized under Aṣṭa Mahāgada because of its complexity and tendency to recur. Case Presentation: A 20-year-old male presented with perianal pain, boil formation, and pus discharge for one month, with a history of fistulotomy performed twice, first in February 2025 and again in May 2025. MRI pelvis revealed a recurrent low intersphincte …

15.08.2026journal-article

International Journal of Innovative Technologies in Social Science

ADJUVANT THERAPY IN MELANOMA: A REVIEW OF CONTEMPORARY TREATMENT STRATEGIES

Gabriela Płodzień, Nikola Król, Aleksandra Łoś, Karolina Majowicz-Czaszyńska, Inga Jakubczyk, Kacper Szkodziński, Jagoda Maternia, Wiktoria Pempuś, Aleksandra Blok, Dominik Wiater, Barbara Tomaszek

Melanoma is a highly aggressive skin cancer with a steadily increasing annual incidence. Although it accounts for only 1% of diagnosed skin cancers, it has the highest mortality rate among them. Therefore, it is essential to continuously develop treatment methods and improve long-term outcomes. In recent years, a breakthrough has been the introduction of adjuvant therapy following surgical treatment, which has become the standard of treatment. This has led to an increase in recurrence-free survival and overall surv …

15.08.2026journal-article

Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)

Nurse-Physician Collaboration in Mitigating Workload-Induced Burnout and Turnover Intention: A Scoping Review of Adaptive Risk Pathways

Muhammad Hafidh Taqiuddin, Ati Surya Mediawati, Hana Rizmadewi Agustina, Muhammad Afiif Aziz, Windu Santoso, Sri Sudarsih, Reni Afriana, Vica Cahya Ningrum

Burnout and turnover intention threaten hospital workforce stability and patient safety. Workload is an established contributor, but how nurse–physician collaboration may interrupt this pathway across hospital contexts remains unclear. This scoping review followed Joanna Briggs Institute methodology, the Population–Concept–Context framework, and PRISMA-ScR guidance. PubMed, Scopus, and EBSCOhost were searched from database inception to 19 May 2026, with eligibility restricted to English-language peer-reviewed empir …

15.08.2026journal-article

ACS Applied Materials & Interfaces

A Non-Invasive Transtympanic Bioadhesive Hydrogel for Sustained Delivery of Dexamethasone in Otitis Media Effusion Therapy

Qian Wan, Hanwei Liu, Shizhe Sun, Ruotong Wang, Jingwei Lai, Wendi Shi, Yuanyuan Xu, Yumeng Jiang, Xianchuang Hu, Ziyuan Li, Minhui Zhu, Junji Zhang, Haibo Shi

Abstract Otitis media with effusion (OME) is a highly prevalent condition characterized by persistent inflammatory effusion in the middle ear cavity. The clinical management of OME remains challenging due to the anatomical inaccessibility of the middle ear, which limits drug efficacy and often necessitates invasive surgical interventions. To address this, we engineered a transtympanic hydrogel platform (Gel-HADA) that undergoes rapid, enzyme-mediated gelation on the tympanic membrane (TM), forming a “second membran …

15.08.2026journal-article

International Journal of Recent Advances in Multidisciplinary Topics

Availability and Utilization of Rehabilitation Services Among People with Disabilities in Maiduguri, Borno State, Northeastern Nigeria

Fatima Lawan Bukar, Bello Umar, Musami Umar Baba, Fatima Sadiq Abdullahi, Zainab Abdullahi Godowoli, Muhammad Mustapha Umar, Maryam Ibrahim, Donald Reuben

Rehabilitation services are interventions designed to optimize functioning and reduce disability in individuals living with disability. Given the growing need for these services, especially in conflict-affected areas like Maiduguri, understanding their availability and utilization is crucial. The aim of the study was to assess the availability and utilization of rehabilitation services among people with disabilities in Maiduguri, Borno state. The study employed a cross-sectional study design. A total of 488 partici …

15.08.2026journal-article

Journal of Science, Technology, and Innovation

Analisis Tingkat Kesesuaian Pintu Darurat pada Bangunan Satuan Pelayanan Pemenuhan Gizi (SPPG) di Kota Bengkulu Berdasarkan Standar Keselamatan dan Kesehatan Kerja (K3): Kajian Konseptual Berbasis Studi Literatur

Riki Setiadi, M. Wisridani P

Emergency exit doors are critical components of building safety systems because they support rapid and safe evacuation during emergencies. This study aimed to analyze the compliance level of emergency exit doors in Satuan Pelayanan Pemenuhan Gizi (SPPG) buildings in Bengkulu City based on SNI 03-1746-2000 and Minister of Public Works Regulation No. 26/PRT/M/2008. A quantitative descriptive approach was employed using purposive sampling involving two SPPG buildings. Data were collected through direct observation usi …