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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 139

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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.09.2026journal-article

Металловедение и термическая обработка металлов

Influence of post-weld heat treatment on microstructure and properties of laser-welded 17-4PH/HR-2 dissimilar stainless-steel joints

Wenhui Xue, Jian Zhao, Yijie Pu, Hangtian Liu, Zixuan Zhang, Ke Han

Лазерная сварка разнородных нержавеющих сталей часто приводит к микроструктурной неоднородности и нестабильности эксплуатационных характеристик сварных соединений из-за их быстрого затвердевания. В данном исследовании лазерная сварка использована для соединения аустенитной стали HR-2 (Х20Н8Г9) и мартенситной нержавеющей стали 17-4PH (09Х17Н7Ю1) с последующей послесварочной термической обработкой (ПСТО) при 760 и 1050 °C. Выполнено систематическое исследование микроструктуры, механических свойств и коррозионной стой …

04.09.2026journal-article

Cancers

Biopsy Provides Actionable Information Associated with Treatment Decisions for 2–7 cm Renal Masses

Daniel F. Roadman, Daniel D. Shapiro, Paz Lotan, Tudor Borza, Isabelle SueJin Lee, J. Louis Hinshaw, Fred T. Lee, Edwarda Golden, Erica Knavel Koepsel, Paul Laeseke, David F. Jarrard, Kyle A. Richards, Elizabeth L. Koehne, Glenn O. Allen, Michael C. Risk, E. Jason Abel

Background/Objectives: Renal mass biopsy (biopsy) is increasingly incorporated into the evaluation of localized renal masses, yet its role in guiding management remains variable among clinical practices. We evaluated the clinical association of biopsy using a simplified classification system categorizing biopsy results as Biopsy Actionable for Immediate Treatment (BAIT) or Biopsy Actionable for Active Surveillance (BAAS)—assessing how biopsy-derived histology influences real-world management. Methods: We identified …

04.09.2026journal-article

BMC Cancer

Clinical outcomes of SMARCA4-deficient thoracic tumor patients and therapeutic value of immune checkpoint inhibitors in advanced stage patients

Qing Jiang, Shuya Mu, Yingjia Sun, Yongfeng Yu

Abstract Objectives SMARCA4-deficient thoracic tumor(SMARCA4-DT) is a relatively rare and highly aggressive tumors, typically associated with mutations or deletions of the SMARCA4 gene. This article aims to explore the clinical features of SMARCA4-DT patients, disease outcomes, effective prognostic indicators, and the therapeutic value of immune checkpoint inhibitors (ICIs) in advanced SMARCA4-DT patients. Methods A total of 98 cases of SMARCA4-DTs diagnosed at Shanghai Chest Hospital from May 2019 to September 202 …

04.09.2026journal-article

Journal of Clinical Medicine

Blood Donation Deferral at a Tertiary Centre in Riyadh: Epidemiology, Sex-Specific Patterns, and Donor Retention Outcomes

Nawaf Oraijah, Muhammad Raihan Sajid, Rimah Abdullah Saleem, Jana H. Husein, Hibba Siraj, Salman Aldosari, Ammar Alsughayir, Mohammed Alkhalifah, Naif Bin Muhanna, Sara Bakr Abobakr, Alyazeed Alsaif

Background: Blood donation deferral poses a significant challenge to transfusion services worldwide, threatening blood supply adequacy and donor retention. Population-specific data on deferral epidemiology and subsequent donor return behavior in Saudi Arabia remain limited. This study aimed to characterize the prevalence, reasons, and demographic patterns of blood donation deferral at King Fahad Medical City (KFMC)—a major quaternary referral center in Riyadh—and to quantify the rate at which temporarily deferred d …

04.09.2026journal-article

Human Reproduction Update

Genetic architecture of endometriosis: risk factors, comorbidities and clinical implications

Grant W Montgomery, Isabelle M McGrath, Michael Toft Overgaard, Mette Nyegaard, Sally Mortlock

Abstract BACKGROUND In 1999, Dr Susan Treloar and colleagues conducted a landmark twin study in Australia and reported their estimate of 51% for the heritability of endometriosis. This important result led several groups to begin mapping genetic factors contributing to increased endometriosis risk. Despite early challenges, advances in genome-wide association studies (GWAS) have identified multiple genetic risk factors and some target genes implicated in follow-up studies on genetic regulation of transcription. Acc …

04.09.2026journal-article

Journal of Computational Design and Engineering

Operational Strategies for Patient Isolation Units to Control Aerosol Transmission: A Computational Fluid Dynamics-based Multi-objective Optimization Approach

Jong Hyeon Lee, Min Hyuk Lim, Jae Woo Shim, Dong Hyun Choi, Byoungjun Jeon, Ki Hong Kim, Jongmo Seo, Changhoon Baek, Sungwan Kim

Abstract The COVID-19 pandemic overwhelmed hospital capacities, prompting the use of patient isolation units (PIUs) to flexibly expand containment in emergency rooms (ERs). However, existing studies primarily rely on static analyses and rarely quantify the direct infection risk to healthcare workers (HCWs). To address these, we propose an integrated framework to simultaneously minimize the aerosol dispersion index (ADI) and infection risk index (IRI) under dynamic conditions. A multistage methodology integrating co …

04.09.2026journal-article

Journal of Clinical Medicine

Intraoperative Arterial Waveform Morphology Trajectories and Prediction of Postoperative Acute Kidney Injury: A Latent-Class Analysis of the VitalDB Registry

Mesher Ensarioğlu, Alperen Kutay Yıldırım

Background: Intraoperative hypotension is an established risk factor for postoperative acute kidney injury (AKI), but whether arterial waveform morphology adds prognostic information beyond the hypotension burden is unknown. Methods: In this study, 2587 adult surgical cases from the Vital Signs Database (VitalDB) with continuous invasive arterial waveforms and creatinine-based (KDIGO) AKI ascertainment were analyzed retrospectively. Maximal systolic upstroke (dP/dtmax), a late-diastolic pressure-decay descriptor (τ …

04.09.2026journal-article

Journal of Wrist Surgery

The Impact of Countersinking Headless Compression Screws on Fracture Compression

Spencer B. Chambers, John Daniel Thompson, Michael B. Gottschalk, Eric R. Wagner, Nina Suh

Abstract Scaphoid fractures are commonly fixated with headless compression screws. These devices generate intrinsic compression that is dependent on the bone-screw interface at the proximal and distal fragments as well as depth of insertion. To minimize the risk of prominent hardware, screws are countersunk beneath chondral surfaces, but the biomechanical implications of this practice have not been explored. The purpose of this study is to characterize fracture compression with and without countersinking in three f …

04.09.2026journal-article

Medicine

Relation between anion gap and 28-day all-cause mortality in patients with chronic total coronary occlusion

Jun Yang, Min Huang, Guofeng Zhu, Zhonglan Cai, Guang Tu

Chronic total coronary occlusion (CTO) is a critical condition associated with poor outcomes in patients with coronary artery disease. Anion gap, a readily available laboratory marker, has been linked to various clinical outcomes, but its relationship with mortality in CTO patients is not well established. This study aimed to investigate the association between anion gap and 28-day all-cause mortality in patients with CTO admitted to the intensive care unit (ICU). We conducted a retrospective cohort study using dat …

04.09.2026journal-article

Medicine

Exploring the role of gut microbiota in coronary atherosclerosis through lipoprotein-mediated cholesterol transport and distribution

Xiaobo Liu, Kailin Shen, Fangtao Zhu, Cunwei Cheng, Haibin Yu

We employed Mendelian randomization (MR) to explore causal relationships between gut microbiota (GM), coronary atherosclerotic heart disease (CAHD), and potential metabolic mediators. We utilized summary statistics from genome-wide association studies (GWAS), encompassing data on 473 GM traits from comprehensive microbiome GWAS, 61 lipoprotein-mediated cholesterol transport and distribution data from large-scale metabolic biomarker studies, and coronary atherosclerosis (CA) data from the GWAS catalog (study accessi …

04.09.2026journal-article

Medicine

Risk evaluation of neck extension in patients with degenerative or ossified cervical spine undergoing extension-dependent surgical procedures

Ye Won Lee, Jong Beom Lee, Min Jai Cho, Hyoung Soo Byoun, Hong Rye Kim, Kyung Soo Min, Mou Seop Lee, Byeong Ho Oh

This study aimed to establish a structured clinical flow for evaluating the risk of iatrogenic spinal cord injury in patients with cervical spine pathology undergoing surgeries requiring neck extension. We retrospectively reviewed 152 patients who underwent anterior neck surgeries requiring cervical extension between March 2022 and February 2024. All patients received preoperative cervical computed tomography (CT) to assess for ossification of the posterior longitudinal ligament, degenerative stenosis, and other co …

04.09.2026journal-article

Cancer Research, Statistics, and Treatment

Postmortem tumor decomposition and environmental dissemination: A narrative review of theoretical ecotoxicological risks

Jerin James, Sanudev SV Puthiyottil

ABSTRACT Patients with cancer harbor a significant oncogenic load, including circulating tumor DNA, extracellular vesicles, and microRNAs, which exhibit relative stability in biofluids. This review explores the theoretical ecotoxicological risks posed by the postmortem release of these tumor-derived biomolecules into the environment. Upon death, decomposition processes facilitate the release of this oncogenic material into soil and water, contributing to the formation of cadaver decomposition islands. We examine th …

04.09.2026journal-article

SAS Journal of Medicine

Takayasu Arteritis Associated with Tuberculosis in the Pediatric Population: A Case Report

Chadine Sefraoui, Daoud Bentaleb, Kamilia Chbani, Dalal Laoudiyi, Siham Salam

Takayasu disease is a rare chronic vasculitis affecting large and medium-caliber arteries, particularly the aorta and its main branches. Rare cases have been reported in the pediatric population, particularly in the initial phase of disease activity. Association with tuberculosis was described. We report a case of a 15-year-old girl, showing active Takayasu disease associated with hypertension in the context of pulmonary tuberculosis. Thoracoabdominal CT angiography revealed involvement of the thoracoabdominal aort …

04.09.2026journal-article

Diabetic Medicine

Participant and physician perspectives on the use of SGLT2 inhibitors in type 1 diabetes

Julia Fielden, Pam Leblanc, Chloe Parezanovic, Vikas S. Sridhar, Bruce A. Perkins, David Z. Cherney, David J. T. Campbell

Abstract Aims Sodium–glucose co‐transporter inhibitors (SGLT2i) have proven cardiorenal benefits in type 2 diabetes and are promising as adjunct‐to‐insulin therapy in participants with type 1 diabetes (T1D). However, clinical use in T1D has been limited owing to a lack of regulatory approval and the augmented risk of diabetic ketoacidosis (DKA). Participant and physician input is critical in understanding how and when the risk–benefit ratio with these therapies is perceived to be favourable for users. This study ai …

04.09.2026journal-article

Advanced Materials Technologies

Hydrogel Microneedles Loaded With a Reactive Oxygen Species (ROS)‐Responsive Carbon Monoxide Donor and Finasteride for Synergistic Treatment of Androgenetic Alopecia

Hui Shi, Zhi Wang, Xinbo Zhang, Xiaoyang Hou, Jingxi Zhang, Dacai Chen, Chunsheng Yang, Guan Jiang

ABSTRACT Androgenetic alopecia (AGA) is highly prevalent, yet its treatment is limited by systemic side effects and poor patient compliance. This study aims to develop a topical delivery system for synergistic, effective, safe, and highly compliant AGA treatment. A methacrylated hyaluronic acid (HAMA)‐based hydrogel microneedle patch (C‐F‐HMN) co‐loaded with a carbon monoxide‐releasing molecule (CORM‐401) and finasteride (FIN) was prepared. CORM‐401 and FIN were formulated into CORM‐401@Pluronic F127 (CO@F127) mice …

04.09.2026journal-article

Current Opinion in Critical Care

Advanced hemodynamic monitoring of the patient with acute heart failure and cardiogenic shock

Antonio Messina, Mathieu Jozwiak, Xavier Monnet

Purpose of review To provide a practical, physiology-driven framework for advanced hemodynamic monitoring in patients with acute heart failure (AHF) and cardiogenic shock, highlighting and supporting clinicians in integrating monitoring tools into an individualized bedside approach. Recent findings Cardiogenic shock is increasingly recognized as a heterogeneous syndrome involving not only impaired cardiac output, but also systemic inflammation, vasoplegia, tissue hypoperfusion and multiorgan dysfunction. Recent stu …

04.09.2026journal-article

Journal of Robotic Surgery

Robotic-assisted transbronchial biopsy versus computed tomography–guided transthoracic needle biopsy for peripheral pulmonary lesions: a systematic review and meta-analysis of direct comparative studies

Atef A. Hassan, Mohamed Mostafa El Sheikh, Amr A. Hassan, Abdelrahman Mady, Mohab Hesham, Yousef Mohamed Hamroush, Shimaa Mostafa Elnahas Wahdan, Mustafa M. Kaff, Mohamed Ashraf Abd El Moniem, Mona Ibrahim Ahmed

Abstract Robotic-assisted bronchoscopy (RAB) and computed tomography–guided transthoracic biopsy (CTTB) are competing strategies for sampling peripheral pulmonary lesions (PPLs). Whether they differ in yield or safety is uncertain. To our knowledge, this is the first systematic review restricted to direct comparisons. We searched MEDLINE, Europe PMC, Scopus, Web of Science and ClinicalTrials.gov from inception to 7 July 2026 for studies directly comparing RAB with CTTB in adults with PPLs. The primary outcome was s …

04.09.2026journal-article

Frontiers in Endocrinology

Pre-Ramadan time-below-range stratifies the simulated pump basal-rate dose–response during Ramadan fasting: a five-policy paired virtual-patient study

Ameen Banjar

Background Pump basal-rate reduction during Ramadan may prevent hypoglycemia but can increase hyperglycemia. Its dose-response relation and phenotype-dependent trade-off remain uncertain. Methods Thirty UVA/Padova virtual patients (10 children, 10 adolescents, 10 adults) underwent paired 30-day Ramadan conditions delivering 100%, 90%, 80%, 70%, or 60% of the pump steady-state basal rate. The primary complete-case analysis included 29 virtual patients. Outcomes were time in range (TIR), time below range (TBR), time …

04.09.2026journal-article

Journal of Cutaneous and Aesthetic Surgery

Dual-mode carbon dioxide laser (continuous and fractional) with 1540 nm non-ablative fractional laser and topical sirolimus in lymphangioma circumscriptum

Ojas Dipak Kulkarni, Ruta Joshi Kulkarni, Charu Garg, Dipak Shridhar Kulkarni

Lymphangioma circumscriptum (LC) is a rare lymphatic malformation majorly localized in the skin. We report a case of 12-year-old girl with LC which was simultaneously treated with carbon dioxide laser (10600 nm) and 1540 nm non-ablative fractional laser, followed by topical sirolimus during and after the procedure for a total of seven sessions. Simultaneous combination of 1540 nm non-ablative fractional and CO2 laser as a targeted therapeutic strategy for LC has been limited to one case in the past, but without the …

04.09.2026journal-article

Frontiers in Pharmacology

The immune-related symptom web in immune checkpoint inhibitor therapy: a longitudinal clinical safety surveillance framework for immune-related adverse events

Bing Li, Haina Che, Yanfeng Song

Immune checkpoint inhibitors (ICIs) produce durable antitumor activity by releasing inhibitory immune pathways, but the same pharmacology can disrupt peripheral tolerance and generate immune-related adverse events (irAEs) that are delayed, recurrent, chronic, multisystem, and clinically nonspecific. Organ-specific guidelines are indispensable once toxicity is suspected; however, clinical surveillance commonly begins with an undifferentiated patient report or an objective abnormality rather than a confirmed organ di …

04.09.2026journal-article

Emergency Care Journal

SpO₂ monitoring in emergency and acute care: clinical utility, limitations, and interpretation pitfalls

Om P. Sanjeev, Utsav Anand Mani, Tapas Kumar Singh, Prerana Kumari

Pulse oximetry provides a non-invasive numerical estimate of arterial oxygen saturation. It is simple to apply and interpret by clinicians at all levels, and its use has expanded substantially across prehospital care, emergency departments, acute care units, and household monitoring. Although pulse oximetry is portable, non-invasive, and cost-effective, its limitations are clinically important because it measures oxygen saturation rather than ventilation, oxygen delivery, or tissue oxygen utilization. Over-reliance …

04.09.2026journal-article

Cells

Fabry Disease: Integrating Molecular Pathophysiology, Precision Diagnosis, and Artificial Intelligence Toward Precision Medicine

Giuseppa Biddeci, Gaetano Spinelli, Paolo Colomba, Monia Anania, Giovanni Duro, Francesco Di Blasi

Fabry disease is a rare X-linked lysosomal storage disorder caused by pathogenic variants in the GLA gene, resulting in deficient α-galactosidase A activity and progressive accumulation of globotriaosylceramide (Gb3) and globotriaosylsphingosine (lyso-Gb3). Although lysosomal substrate storage represents the primary molecular defect, accumulating evidence indicates that disease progression is driven by interconnected mechanisms, including chronic inflammation, oxidative stress, endothelial dysfunction, and impaired …

04.09.2026journal-article

Scientia Pharmaceutica

Translating the Properties of Physicochemical Dressings into Clinical Decision-Making for Heavily Exuding Wounds

Paulina Sánchez-Toledo, Rosa M. Salgado, Silvestre Ortega-Peña, Edgar Krötzsch

Introduction: Heavily exuding wounds can macerate perilesional skin and favour infection. Information on the properties and use time of dressings should be clear and available to healthcare providers. Methods: Our aim was to evaluate the updated series of the AQUACEL® dressing family, because their evolution from a single layer of carboxymethylcellulose (NaCMC) to a multicomponent antiseptic or its combination with polyurethane covered with a silicon layer has developed the technology beyond simple exudate absorpti …