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EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Onkologie · Seite 138

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Basic & Clinical Pharmacology & Toxicology

Regional Variation in ADHD Treatment and Diagnosis Among Children and Adolescents in Denmark

Heidi Sonne, Anton Pottegård, Anna Sofie Kjærgaard Hansen, Mickael Bech, Helene Kildegaard

ABSTRACT Geographic variation in ADHD treatment and diagnosis among children and adolescents is well documented, yet the system‐level factors driving such differences remain poorly understood. We examined nationwide patterns of ADHD medication use and diagnoses in Denmark in 2024 and assessed whether municipal socioeconomy, regional hospital waiting times or private child psychiatrist capacity contributed to geographic variation. In this register‐based cross‐sectional study, we included all Danish residents aged 4– …

30.08.2026journal-article

HEALTH SCIENCES AND DISEASE

Infection à Papillomavirus Humain et Lésions Précancéreuses du Col Chez les Travailleuses de Sexe à Parakou (Bénin) en 2025 : Prévalence et Acceptabilité du Traitement

Atade Sèdjro Raoul, Sidi Imorou Rachidi, Vodouhe Mahublo Vinadou, Yessoufou Junior Abd’ousmane, Klikpezo Roger, Bakary Samiath, Doha Valdes, Salifou Kabibou

RÉSUMÉIntroduction. Les travailleuses de sexe constituent une population à haut risque d'infection à Papillomavirus humain (HPV) et de lésions précancéreuses du col de l'utérus. Au Bénin, les données sur le dépistage et le traitement dans ce groupe vulnérable sont rares. Cette étude visait à déterminer la prévalence des lésions précancéreuses et à évaluer l'acceptabilité du traitement chez les travailleuses de sexe à Parakou en 2025. Méthodes. Nous avons mené une étude transversale descriptive du 3 août au 20 septe …

30.08.2026journal-article

physica status solidi (a)

Multilayer WS 2 /Borophene/Au/MXene/Cu Metasurface Terahertz Biosensor With Machine Learning‐Augmented Prediction for Label‐Free Brain Tumor Detection

Hassan Nasiri, Amuthakkannan Rajakannu

High‐performance terahertz metasurface biosensor is numerically developed for label‐free brain tumor detection. The sensor employs six multilayer elliptical resonators integrating WS 2 , borophene, Au, MXene, and Cu on a graphene‐coated SiO 2 substrate. Three material configurations are compared, with the hybrid WS 2 /borophene/MXene/Cu structure (Case 3) enabling plasmon–exciton (plexcitonic) coupling and delivering the best performance. Full‐wave FEM simulations in COMSOL incorporate dispersive material models, g …

30.08.2026journal-article

International Journal of Research in Ayurveda and Pharmacy

FORMULATION AND EVALUATION OF MUCOADHESIVE HERBAL ORAL GEL CONTAINING SCUTELLARIA BAICALENSIS EXTRACT FOR THE TREATMENT OF ORAL INFLAMMATORY CONDITIONS

Aditya Uttam Waghmare, Pratik Sanjeev Gunale, Kiran C. Rodage, Sameer Shafi, Dharashive VM, Kavita Shivkumar Sirgire

The present study aimed to formulate and evaluate a mucoadhesive herbal oral gel containing Scutellaria baicalensis extract for the treatment of oral inflammatory conditions. The plant extract, rich in flavonoids such as baicalin and baicalein, exhibits significant anti-inflammatory, antimicrobial, and antioxidant properties. Herbal gel formulations (F1-F6) were prepared using Carbopol 940 as a gelling agent with varying concentrations to optimise physicochemical and release characteristics. The formulations were e …

30.08.2026journal-article

Advanced Science

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo

ABSTRACT Developing effective therapies for triple‐negative breast cancer (TNBC) requires the identification of key molecular regulators. Here, among the major m6A modulators, we find that only the reader YTHDC1 is specifically overexpressed in TNBC and correlates to unfavorable prognosis. Mechanistically, YTHDC1 orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress in TNBC cells. It not only stabilizes GLUT3 mRNA to sustain glucose uptake …

30.08.2026journal-article

Eskisehir Medical Journal, Eskisehir City Hospital

TREATMENT STRATEGY AND INTERVENTION TIMING IN ELDERLY PATIENTS WITH ACUTE MESENTERIC ISCHEMIA: A MULTICENTER RETROSPECTIVE COHORT STUDY

Mehmet Emin Gonullu, Ahmet Tugrul Zeytin, Gurkan Guneri, Kadir Corbaci, Mucahit Unal, Fatih Gursoy, Erman Yekenkurul

Introduction: This study aimed to evaluate the association between treatment modality, intervention timing, and clinical outcomes in patients aged 65 years or older with acute mesenteric ischemia (AMI). Methods: This multicenter retrospective cohort study included 126 patients aged 65 years or older who were diagnosed with AMI between January 2015 and December 2025. Patients were classified according to treatment modality as endovascular treatment, open surgery, or conservative management. The primary outcome was 3 …

30.08.2026journal-article

Ukrainian Heart Journal

Ізольована дисекція верхньої брижової артерії: ендоваскулярне лікування. Клінічний випадок

S. M. Furkalo, Yu. H. Vahis, A. O. Danylets

The aim – to describe a case of elective endovascular treatment of asymptomatic spontaneous isolated dissection of the superior mesenteric artery with a self-expanding covered stent via right transbrachial access and to justify the indication for intervention based on morphological risk criteria.Materials and methods. The follow-up of a 67-year-old man with coronary artery disease, compensated type 2 diabetes mellitus, arterial hypertension, dyslipidaemia and previous left total hip arthroplasty is presented. The d …

30.08.2026journal-article

Anatolian Journal of Health Research

The relationship between infertility stress, coping, and quality of life among women undergoing infertility treatment

Büşra Çark, Seyhan Çankaya, Ümmügülsüm Esenkaya

Aim: This study aimed to examine the relationships between infertility-related stress, coping strategies, and quality of life among women undergoing infertility treatment. Methods: This descriptive, cross-sectional study was conducted between April-November 2025 with 200 women attending an infertility outpatient clinic at a city hospital in Central Anatolia, Türkiye. Data were collected using a Personal Information Form, the COMPI Fertility Problem Stress Scales, the COMPI Coping Strategy Scales, and the Fertility …

30.08.2026journal-article

European Heart Journal

Safety of withdrawal of pharmacological treatment after recovery from HER2 therapy-related cardiac dysfunction: the HER-SAFE trial

B Dowsing, H-M Dehbi, M S Andres, R Chung, A Oashou, J M Wilson, I Hussein, B Meredith, I Pierce, S Ahmed, J Pedra, O Worn, M Howe, S Assadullah, P Schmid, R Roylance, T Crake, M Westwood, A K Ghosh, D Auger, C M Plymen, J Baksi, M S Nazir, J C Moon, D Chen, A R Lyon, J M Walker, C H Manisty

Abstract Background Heart failure therapy (HFT) is routinely continued in breast cancer survivors after recovery from anti-HER2 cancer therapy-related cardiac dysfunction (CTRCD), despite limited evidence. HER-SAFE is the first randomised trial to assess HFT withdrawal in this population. Methods In this open-label, multicentre, randomised controlled trial, breast cancer survivors with recovered anti-HER2 CTRCD (asymptomatic, left ventricular ejection fraction [LVEF] ≥50%, normalised biomarkers) were randomised to …

30.08.2026journal-article

MedComm

Artificial Intelligence Integration With Nanotechnology for Cancer Therapy

Shengbin Liu, Zhi Liu, Haixing Shi, Chengyi Wei, Ruijie Zhang, Xiangrong Song

ABSTRACT Cancer nanomedicine offers a versatile platform for improving therapeutic index, but its clinical translation remains limited by unpredictable in vivo behavior, heterogeneous biological contexts, and inefficient design paradigms. Artificial intelligence (AI) is emerging as an integrative framework that links data‐driven modeling with nanomedicine design, biological transport, and clinical decision‐making. In this review, we discuss AI‐guided strategies for material design, targeting, payload optimization, …

30.08.2026journal-article

Phlebology: The Journal of Venous Disease

Clinical treatment strategies and perioperative management of restenosis or secondary deep venous thrombosis after iliac vein balloon angioplasty

Zi-shuo Yang, Shuang-jie Tang

Objective To explore the surgical selection of iliac vein balloon angioplasty, as well as the treatment and management of postoperative complications including restenosis and secondary deep venous thrombosis. Methods All 55 enrolled patients received routine telephone follow-up, and imaging reexamination and statistical analysis were only performed on 10 patients complicated with restenosis or secondary thrombosis after balloon angioplasty. Conclusion This study provides reference basis for the selection of clinica …

30.08.2026journal-article

Medicina

Radiotherapy Modality and Primary Tumor Type as Determinants of Outcomes in Brain Metastases: A Retrospective Study of 734 Patients

Lucie Hnidakova, Andrea Pagacova, Sarka Kristkova, Jan Svancara, Ludmila Hynkova, Petr Pospisil, Renata Belanova, Jana Maistryszinova, Radek Lakomy, Tomas Prochazka, Miroslav Vrzal, Jiri Sana, Radim Jancalek, Martin Smrcka, Ivana Kolouskova, Lukas Moran, Katerina Prochazkova, Vera Andraskova, Jan Garcic, Pavel Slampa, Pavel Fadrus, Tomas Kazda

Background and Objectives: Radiotherapy (RT) is a standard component of palliative treatment for brain metastases. The aim of this retrospective analysis of consecutive patients treated between 2017 and 2023 is to analyze overall survival after brain radiotherapy depending on the type of radiotherapy delivered and to monitor the shift from whole-brain radiotherapy (WBRT) to stereotactic radiotherapy (SRS/FSRT) in real-world practice before the era of routinely used modern brain-penetrant targeted therapy. Materials …

30.08.2026journal-article

Cancer Medicine

Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study

Lotte Pitlo, Francis S. P. L. Wens, Paulien A. M. A. Raymakers‐Janssen, Lianne M. Haveman, Johannes H. M. Merks, Martine van Grotel, Geert O. Janssens, Marta Fiocco, Marry M. van den Heuvel‐Eibrink, Gerrit van den Berg

ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce. This study aimed to determine the prevalence, course, and determinants of CKD in ifosfamide‐treated children within the first five years after chemotherapy. Methods This cohort study included children treated with ifosfamide at the Princess Máxima Center …

30.08.2026journal-article

Cellular Oncology

The role of hSSB1 and hSSB2 in the DNA damage response: mechanisms and implications

Armin Sharifi, Amila Suraweera, Kenneth J. O’Byrne, Derek J. Richard

Abstract The DNA damage response preserves genome integrity by detecting DNA lesions, activating checkpoint signalling, and coordinating repair with cell-cycle control. Defective or incomplete repair can promote mutation accumulation, chromosomal instability, cancer development, and ageing-associated diseases. In this review, we discuss the human single-stranded DNA-binding proteins hSSB1 and hSSB2, with an emphasis on their roles in ssDNA-rich repair intermediates generated during double-strand break repair, repli …

30.08.2026journal-article

Frontiers on Healthcare Research

What Explains the Survival Gap? Decomposing Cross-National Inequality in Breast Cancer Mortality-to-Incidence Ratios Using Open Global Data Repositories

Graduate Institute of Translational Medicine and New Drug Development, College of Medicine, China Medical University, Taichung, Taiwan, Siti Mardhiah El-Khairah Siti Mardhiah, Department of Epidemiology, Faculty of Public Health, Universitas Andalas, Padang, Indonesia, Melsi Pita Sari Melsi Pita

Background: Women diagnosed with breast cancer in low-resource countries are several times more likely to die from the disease than those in high-income countries, despite lower incidence. The mortality-to-incidence ratio (MIR) captures this survival gap, but previous studies have mainly described its association with national wealth rather than quantified the contribution of specific health-system factors. We aimed to measure inequality in breast cancer MIR across the human development gradient and identify key de …

30.08.2026journal-article

Advanced Science

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov

ABSTRACT Targeting nanoparticles to cancer cells in vivo remains a challenge for cancer imaging. We assessed nanoparticle distribution after injecting iron oxide nanoparticles conjugated with either a monoclonal anti‐HER2 (human epidermal growth factor 2), or a non‐specific IgG antibody into a human HER2 overexpressing murine breast cancer model. We used Magnetic Particle Imaging (MPI) and histopathology to assess particle localization at 72 h after injection. MPI detects magnetic moments produced by magnetic parti …

30.08.2026journal-article

Biomedicines

Basic Periodontal Treatment Improves Periodontal Inflamed Surface Area Without Adverse Events in Patients Receiving Direct Oral Anticoagulants: A Retrospective Clinical Study with an Animal Model

Ryousuke Fujimori, Yuri Taniguchi, Kazuhisa Ouhara, Shunsuke Miyauchi, Shinji Matsuda, Naoya Kuwahara, Shoya Ueda, Yitong Hou, Masaru Shimizu, Misako Tari, Shoko Kono, Tomoyuki Iwata, Tomoaki Shintani, Mikihito Kajiya, Mutsumi Miyauchi, Yukiko Nakano, Noriyoshi Mizuno

Background/Objectives: The optimal management of periodontal treatment in patients receiving direct oral anticoagulants (DOACs) remains poorly established, and bleeding concerns may lead clinicians to delay or limit treatment. We evaluated the clinical efficacy and safety of nonsurgical periodontal treatment in patients receiving DOAC therapy. Methods: This retrospective study included 67 patients receiving continuous DOAC therapy (edoxaban, apixaban, dabigatran, or rivaroxaban) who underwent nonsurgical periodonta …

30.08.2026journal-article

International Journal of Molecular Sciences

Systemic Immune-Inflammatory Biomarkers in Epithelial Ovarian Cancer: Subgroup-Dependent Prognostic Performance and Integrated Risk Stratification

E Sun Paik, Young Eun Chung, Seoyoung Youn, Seongyun Lim, Jun-Hyeong Seo, Chel Hun Choi, Tae-Joong Kim, Jeong-Won Lee, Yoo-Young Lee

Systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are surrogate markers of the systemic immune-inflammatory response proposed as perioperative prognostic biomarkers in epithelial ovarian cancer (EOC), yet their performance across subgroups remains unexamined. In 373 EOC patients undergoing primary cytoreductive surgery, postoperative day-1 changes (ΔSII, ΔNLR, ΔPLR) were compared for overall survival (OS) and progression-free survival (PFS) across …

30.08.2026journal-article

Journal of Clinical Nursing

Nursing‐Led Models of Tracheostomy Management for Patients With Head and Neck Cancer: A Mixed‐Methods Study

Sarah Davies, Carsten Palme, Faruque Riffat, Emma Charters

ABSTRACT Background The incidence of head and neck cancer (HNC) is rising globally, with patients undergoing extensive surgical resection for advanced disease frequently requiring prophylactic tracheostomy to secure the airway in the early postoperative period. Specialised HNC nurses undertake extended scope tracheostomy procedures, including tube changes and decannulations, yet practice varies widely between institutions and no standardised training framework exists. Aims and Objectives To benchmark the roles and …

30.08.2026journal-article

Journal of Research and Investigation in Education

Development of a Web-Based Expert System for Cancer and GERD Diagnosis

Aprilia Adelina Roring, Gilbert Josua Mangkay, Jean Stella Saragih, Ricat Abetnego Sundari, Jhosua Allesandro Tingon, Paul Aleksander Mundung, Yulisa Aprianti

Cancer and Gastroesophageal Reflux Disease (GERD) are serious health problems whose early detection is often hampered by limited access and awareness. This research aims to develop a website-based expert system as a solution to help the public perform an initial diagnosis of cancer and GERD independently. The system development methodology includes a requirements analysis phase, data flow design using DFD and ERD, and implementation using Visual Studio Code with programming languages ​​such as Python and JavaScript …

30.08.2026journal-article

Brain Pathology

Complement receptor C3aR marks heterogeneous tumor‐associated macrophage states associated with improved survival in IDH ‐wildtype glioblastoma

Marion Imara, Yosra Bedoui, Théotime Pignolet, Sebastien Freppel, Camille Brochard, Auguste Delattre, David Cappellen, Luc Bauchet, Mohamed Khettab, Franck Ah‐Pine

Abstract Glioblastomas (GBM), IDH‐wildtype, are highly aggressive brain tumors with poor prognosis and inter‐individual variability despite established prognostic factors such as age, performance status, and MGMT promoter (MGMTp) methylation. Increasing evidence highlights the role of the tumor microenvironment (TME) in GBM progression. The complement system, a key component of innate immunity, can influence tumor growth and immune regulation through the generation of the anaphylatoxin C3a and the activation of its …

30.08.2026journal-article

npj Breast Cancer

Genomic characterization of ER-positive primary tumors and corresponding relapses identifies potentially targetable alterations

Caroline Schagerholm Stanev, Stephanie Robertson, Hosein Toosi, Emmanouil G. Sifakis, Jens Lagergren, Johan Hartman

Abstract The majority of breast cancer patients have tumors expressing estrogen receptor α (ER) and receive endocrine therapy. However, around one-third relapse in their disease, predominantly with retained ER expression. Molecular alterations are proposed to be contributors to the resistance mechanisms. Patients with ER-positive, human epidermal growth factor receptor 2 (HER2)-negative primary breast cancer with an ER-positive relapse

30.08.2026journal-article

HEALTH RESEARCH IN AFRICA

Effectiveness of the Ponseti Method for Clubfoot Treatment in Children in Chad : A 77‑Case Study

Salhadine Yacoub Ahmat, Bembo Lamega, Mahamat Nour Abakar Djibrine, Ngaringuem Olivier, Moyalbaye Yireta, Dezoumbet Olivier, Sobdjolbo Olivier, Souad Abakar, Choua Oucheimi

RÉSUMÉIntroduction. Le pied bot varus équin (PBVE) est une déformation congénitale tridimensionnelle du pied, associant un équin du talon, un varus de l'arrière-pied et une rotation interne du bloc calcanéo-pédieux. En Afrique subsaharienne, son traitement reste un défi en raison du coût des approches chirurgicales et de l'accès limité aux soins spécialisés. La méthode de Ponseti, non invasive et peu coûteuse, pourrait offrir une solution adaptée à notre contexte, mais ses résultats dans les pays en développement s …