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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 136

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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.09.2026journal-article

Frontiers in Medicine

An update on the diagnosis and treatment of seborrheic keratosis

Sri Nauli Dewi Lubis, Imam Budi Putra

Background Seborrheic keratosis (SK) is a common benign epidermal neoplasm, particularly affecting the elderly. Although non-malignant, it often poses cosmetic and diagnostic challenges due to its resemblance to malignant skin tumors. This review aims to provide a comprehensive update on the recent advancements in the epidemiology, pathogenesis, diagnostic modalities, and therapeutic approaches for SK. Methods A narrative review of current literature was conducted, focusing on molecular insights, diagnostic innovat …

04.09.2026journal-article

Frontiers in Cell and Developmental Biology

Progress on hydrogel delivery systems targeting metabolism disorders in the treatment of diabetic foot ulcers

Shihua Liu, Lixian Huang, Hong Dong

Diabetic foot ulcer (DFU) is a severe and difficult-to-heal complication of diabetes in which systemic metabolic dysregulation is translated into local neurovascular injury and dysfunction of wound-healing cells. This narrative review examines the relationships among glucose, lipid, and amino acid/protein metabolism disorders, the dysfunction of macrophages, fibroblasts, and endothelial cells, and hydrogel-based therapeutic strategies. Persistent hyperglycemia disrupts the tricarboxylic acid cycle, activates the po …

04.09.2026journal-article

ANZ Journal of Surgery

How to Do 10 mL Syringe Port Retroperitoneal Access for Staged Minimally Invasive Pancreatic Necrosectomy

Katharine Ji, Adrian Fox, Matthew Marshall‐Webb

ABSTRACT Acute necrotising pancreatitis with infected pancreatic necrosis has a significant mortality of up to 23.5%, with survival dependent on achieving a complete necrosectomy. In recent years, several minimally invasive techniques have been developed including laparoscopic and endoscopic approaches, which are feasible, well‐tolerated and beneficial for the patient when compared with open surgery. Percutaneous drainage with radiologically guided drains has limited efficacy as pancreatic necrosis is mostly solid …

04.09.2026journal-article

Frontiers in Endocrinology

Synergistic effect of insulin resistance and glycemic variability on mortality in ICU patients with gastrointestinal bleeding: impact of the TyG-GVI index and development of an explainable web-based clinical calculator

Yanqiu Jiang, Keyang Guo, Kexin Jiang, Shengshan Xu, Ke-Jie He

Objective To investigate the association between the composite Triglyceride-Glucose Index combined with Glycemic Variability (TyG-GVI) and early-death risk in ICU patients with gastrointestinal bleeding, and evaluate whether integrating this biomarker into ensemble-learning models improves prognostic performance. Methods This retrospective study analyzed adult ICU patients (≥18 years) with gastrointestinal hemorrhage as the principal diagnosis from the MIMIC-IV v3.1 database. TyG-GVI was calculated as the product o …

04.09.2026journal-article

Oncologie

PFB-03 study protocol: diagnostic performance and clinical application of 18 F-FAPI-PET/CT for detecting axillary metastasis in breast cancer patients after neoadjuvant therapy

Ru Yao, Yang Qu, Zhixin Hao, Jiahui Zhang, Jie Lian, Aocheng Wu, Songjie Shen, Feng Mao, Bo Pan, Qiang Sun, Li Huo, Yidong Zhou

Abstract Objectives Axillary lymph node (ALN) status is a crucial prognostic factor in breast cancer. Accurate, non-invasive methods for evaluating axillary lymph node metastasis after neoadjuvant therapy (NAT) are needed to optimize surgical decisions and minimize patient morbidity. Fibroblast activation protein inhibitor (FAPI) PET/CT targets cancer-associated fibroblasts and may improve diagnostic accuracy. This study aims to assess the diagnostic performance and clinical utility of 18 F-FAPI PET/CT in detecting …

04.09.2026journal-article

Hormone and Metabolic Research

Recent Advances in Glucagon-Like Peptide-1 Receptor and Melanocortin-4 Receptor Agonists for the Treatment of Obesity and Type 2 Diabetes

Chang-Min Lee, Jin-Young Kim, Jeong-Hyun Shim, Gwang-won Cho

Abstract The global rise in aging populations has been accompanied by increasing rates of obesity and type 2 diabetes, both of which pose significant public health and economic challenges. This review aims to investigate the pathophysiological link between obesity and diabetes and evaluate emerging therapeutic strategies that involve glucagon-like peptide-1 receptor and melanocortin-4 receptor agonists, including their dual and triple agonist developments. A comprehensive literature review was conducted focusing on …

04.09.2026journal-article

JEADV Clinical Practice

Dietary Patterns in Patients With Hidradenitis Suppurativa

Maria Victoria Gerdes‐Miranda, Marianne Bengtson Løvendorf, Simon Francis Thomsen, Lone Skov, Charlotte Näslund‐Koch

ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic immune‐mediated inflammatory skin disease associated with obesity and metabolic syndrome. However, the role of diet is still unexplored. Objectives The aim of this study was to describe dietary habits in patients with HS and to examine the association between an unhealthy diet and disease severity. Methods In this cross‐sectional study we included patients with HS from out‐patient clinics of two different departments of dermatology. Patients were enroll …

04.09.2026journal-article

Frontiers in Medicine

From hematuria warning to precision immunotherapy: an AI-assisted cross-platform analysis of bladder cancer information on social media

Peng Han, Xin Yang, Qiuxiang Li, Pengcheng Lu, Penghuan Wang, Zhonglei Deng, Zeping Gui, Yiping Zong, Mingyu Liu

Objective Bladder cancer often presents with hematuria, while modern management increasingly depends on pathology-based risk stratification, immunotherapy, and biomarker-informed treatment. This study evaluated whether social media videos adequately connect early hematuria warning with precision bladder cancer care. Methods We conducted a cross-sectional, AI-assisted structured extraction and urologist consensus-scored content analysis of publicly available videos from Bilibili, Douyin, and YouTube. Videos were sea …

04.09.2026journal-article

Innovative Medicine of Kuban

Stress Levels in Anesthesiologists and Intensivists: A Prospective Multicenter Observational Study

V. E. Ironosov, K. V. Pshenisnov, Yu. S. Aleksandrovich, V. Yu. Talaiko, V. S. Potapov, A. V. Soboleva, F. G. Ulmasov

Anesthesiology and intensive care medicine is one of the medical specialties in which professional practice is associated with frequent stress and the development of burnout syndrome. Objective : To assess the level of stress in anesthesiologists and intensivist according to the characteristics of their professional practice and length of clinical experience. Materials and methods : An anonymous survey was conducted among 138 anesthesiologists and intensivists, including 79 (57.2%) women and 59 (42.8%) men. The que …

04.09.2026journal-article

Innovative Medicine of Kuban

Surgical Treatment of Atrophic Femoral Shaft Nonunion

D. A. Zelyanin, V. E. Dubrov, L. V. Abramenkova, M. L. Mukhanov

This review aims to identify the advantages and limitations of the treatment strategies for atrophic femoral nonunion and is based on the analysis of 358 publications (from 1973 to 2025). The literature search was conducted using the PubMed (MEDLINE) and eLibrary databases in accordance with the PRISMA guidelines for systematic reviews. The analysis demonstrated that the majority of the publications consist of single case reports or small case series. No universally accepted standard for the treatment for this cond …

04.09.2026journal-article

Complex Issues of Cardiovascular Diseases

BIOMATERIALS IN AORTIC ROOT SURGERY: MID-TERM OUTCOMES

Roman N. Komarov, Maxim I. Tkachev, Elizaveta A. Palaznik, Nikoloz I. Kviloriya, Armais A. Galstyan, Daniil V. Rodin, Maria V. Pipnik, Grayr G. Shabunts, Diana O. Mdivnishvili, Margarita P. Zaikina

Highlights For the first time, a comparative study was conducted of the medium‑term results of using aortic homografts, autografts (Ross operation), and a domestic biological conduit in the surgical treatment of aortic root pathology. It has been shown that all three biomaterials provide high survival rates, acceptable freedom from reoperations, and stable hemodynamics in the medium term. The data obtained indicate the clinical viability of the domestic biological conduit as a competitive alternative to traditional …

04.09.2026journal-article

Physics in Medicine & Biology

CAFDIM: A Group Convolution and Self-Attention Fusion-Based Dual-Domain Iterative Method for Sparse-View CT Reconstruction

Jizhong Duan, Chenghong Sun, Haibo Tao, Zhenyu Huang, Yu Liu

Abstract Objective. Sparse-view computed tomography (CT) reduces radiation dose and acquisition time by decreasing the number of projection views, but it also makes image reconstruction severely ill-posed, leading to structural distortion and severe artifacts. This study aims to develop an effective reconstruction framework for improving both projection-data fidelity and reconstructed image quality in sparse-view CT. Approach. We propose a group Convolution- and self-Attention Fusion-based Dual-domain Iterative Met …

04.09.2026journal-article

Medicine & Science in Sports & Exercise

Long-Term Career and Healthcare Impacts of Hip/Pelvic Bone Stress Injuries Sustained During Basic Combat Training: A Case-Control Study in Graduates

Garry F. Dredge, Daniel I. Rhon, Abe R. Dummar, Brian W. Noehren, Johanna M. Hoch, Nicholas R. Heebner

Background: Hip and pelvic bone stress injuries (BSIs) represent a small but clinically significant subset of overuse injuries sustained during U.S. Army Basic Combat Training (BCT). However, the long-term military service and healthcare implications remain unclear. This study examined the impact of hip and pelvic BSIs sustained during BCT on subsequent military career outcomes and musculoskeletal healthcare utilization. Methods: In this case-control study, BCT graduates from fiscal years 2015 to 2017 were analyzed …

04.09.2026journal-article

Clinical and Translational Gastroenterology

Splenic Elastography as a Predictor of Gastroesophageal Varices in Cirrhosis

Jorge Pacheco Oliva, Ninoska Isamar Meléndez Rodríguez, Abel Alberto Sánchez Orozco

Introduction: Gastroesophageal varices are a major complication of portal hypertension in cirrhosis, associated with high morbidity and mortality. Noninvasive predictors are needed to reduce reliance on endoscopy. Splenic elastography has emerged as a potential tool to assess portal hypertension severity. Methods: We conducted prospective, descriptive cross-sectional study at Hospital Roosevelt, Guatemala, in 2024, including 78 patients with recent diagnosis of cirrhosis confirmed by ultrasonography. Patients with …

04.09.2026journal-article

Tropical Medicine and Health

Maternal, newborn, and child health continuum of care: completion and associated factors in Xiengkhuang and Huaphanh, Lao PDR

Hyejung Han, Khammany Phommachanh, Sung Hye Kim

Abstract Background Completing the full continuum of maternal, newborn, and child health (MNCH) care remains challenging in remote Lao PDR, which has among the highest maternal and neonatal mortality rates in Southeast Asia. Evidence on continuum of care (CoC) completion and its determinants is limited for Xiengkhuang and Huaphanh, two underserved provinces. Methods A community-based cross-sectional household survey was conducted in February 2023 using stratified three-stage cluster sampling across eight districts. …

04.09.2026journal-article

Journal of modern medicine

CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF ATOPIC DERMATITIS SEVERITY IN CHILDREN: THE ROLE OF TOTAL IGE, EOSINOPHILIA, AND POLYSENSITIZATION

I.S. Razikova, Sh.K. Khodjaeva, G.R Razikova

Atopic dermatitis is a common chronic inflammatory skin disease in children, with considerable heterogeneity in clinical course and severity associated with immunological activity and patterns of allergen sensitization. The aim of this study was to evaluate the relationship between the clinical severity of atopic dermatitis and total immuno­globulin E (IgE), peripheral blood eosinophilia, and the extent of sensitization in children. The study included 200 children aged 3–18 years with a confirmed diagnosis of atopi …

04.09.2026journal-article

European Journal of Haematology

Treatment Patterns, Outcomes and Survival Trends in T‐Cell Prolymphocytic Leukemia: A Nationwide Population‐Based Study in the Netherlands

Mirian Brink, Arie C. van der Spek, Jeanette K. Doorduijn, Koen de Heer, Sabina Kersting, Lidwine W. Tick, Doreen G. te Raa, Hanneke M. van der Straaten, Gerrit Jan Veldhuis, Laurens Laterveer, Rogier Mous, Mark‐David Levin, Kees Meijer, Andre Mulder, M. Nijland, Gerwin Huls, Arnon P. Kater, Mar Bellido

ABSTRACT Background T‐cell prolymphocytic leukemia (T‐PLL) is a rare, aggressive mature T‐cell malignancy with limited therapeutic options. Alemtuzumab remains the backbone of therapy, and fit responders are consolidated with allogeneic stem cell transplantation (alloSCT). However, contemporary population‐level outcomes remain poorly defined. Methods All T‐PLL cases diagnosed between 2001 and 2023 were identified from the nationwide Netherlands Cancer Registry. Overall survival (OS) and survival after relapse (OS2) …

04.09.2026journal-article

Oral

Post-Treatment Aesthetic Perception and Facial Satisfaction After Mandibular Angle Volumization with Hyaluronic Acid: A Preliminary Prospective Clinical Study

Nicole Barbosa Bettiol, Selma Siéssere, Giovana Dornelas Azevedo Romero, Franciele Aparecida de Carvalho, Márcio de Menezes, Luana Cristina de Freitas, Jardel Francisco Mazzi-Chaves, Laís Valencise Magri, Simone Cecilio Hallak Regalo, Marcelo Palinkas

Background/Objectives: Mandibular angle volumization with hyaluronic acid is used to redefine facial contours and improve the aesthetics of the lower third of the face. However, beyond the aesthetic outcomes, it is important to understand the impact of this intervention on the aesthetic perception of subjects undergoing the procedure. This preliminary prospective, non-randomized, uncontrolled clinical trial aimed to evaluate post-treatment aesthetic satisfaction and facial appearance perception in subjects who unde …

04.09.2026journal-article

S.S. Korsakov Journal of Neurology and Psychiatry

Matrix metalloproteinases and vascular endothelial growth factor in the acute phase of ischemic stroke: correlation with pathogenetic subtypes and clinical outcomes

K.S. Kucherova, E.S. Koroleva, V.M. Alifirova, N.G. Brazovskaya, L.A. Levchuk, A.S. Boiko, S.A. Ivanova

Objective. To evaluate the changes in serum levels of matrix metalloproteinase (MMP)-2, MMP-9, and vascular endothelial growth factor (VEGF) during the acute phase of ischemic stroke (IS) to elucidate subtype-specific pathogenetic mechanisms and assess the predictive value of these biomarkers for clinical and functional recovery in patients. Material and methods. The study included 114 patients diagnosed with IS. Participants were categorized into the following groups: Group 1 (n=26) with atherothrombotic stroke, G …

04.09.2026journal-article

Frontiers in Public Health

Relapse prediction and individualized treatment-effect modeling in relapsing multiple sclerosis: a systematic review

Martin Budil, Martin Rožánek, Petra Petrová

Introduction Individualized prediction of relapse-related outcomes may support treatment selection and monitoring in relapsing multiple sclerosis. However, existing studies differ substantially in clinical purpose, target outcomes, modeling approaches, and validation strategies. Methods We conducted a systematic review in accordance with PRISMA 2020. PubMed, Web of Science, IEEE Xplore, and Scopus were searched for English-language records published from 1 January 2010 to 14 January 2026. Studies developing or eval …

04.09.2026journal-article

Journal of the American College of Surgeons

Lyon Consensus 2.0 vs Conventional Surgical Criteria for Predicting Favorable Outcomes After Antireflux Surgery

Sven E Eriksson, Vineeth Sadda, Ahmed Aly, Tasneem Ekhtiar, Inanc S Sarici, Ping Zheng, Shahin Ayazi

Background: Lyon Consensus 2.0 revised the criteria for conclusive GERD by including grade B esophagitis and requiring abnormal acid exposure on at least 2 monitoring days for physiologic confirmation. Whether these criteria improve selection of patients for antireflux surgery (ARS) remains uncertain. We compared Lyon 2.0 with conventional surgical criteria for their association with favorable postoperative outcomes. Study Design: Patients undergoing ARS after preoperative endoscopy and 48-hour wireless pH monitori …

04.09.2026journal-article

Journal of Clinical Medicine

Clazosentan Administration Was Not Associated with Intracranial Pressure Elevation in Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study with Direct ICP Monitoring

Yo Nishimoto, Tadashi Miura, Ken Shinno, Yongran Yanase, Nao Kagimoto, Shota Nishimoto, Satoru Hayashi, Hitoshi Fukuda

Background/Objectives: Clazosentan reduces cerebral vasospasm and delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage (aSAH). However, concerns that clazosentan may cause cerebral edema and increase intracranial pressure (ICP) have discouraged its use in patients with poor-grade aSAH. Methods: This single-center retrospective study included 59 patients with aSAH who underwent continuous direct ICP monitoring, of whom 23 received clazosentan and 24 received fasudil. Most clazosentan-treated patien …

04.09.2026journal-article

Journal of Translational Medicine

Decreased mechanosensitivity and metabolic reprogramming impair bone regeneration in type II diabetes: core mechanism and targeted scaffold design

Yongqiang Mo, Linqin Tang, Jingwei Zhang, Weitao He, Jingtao Chen, Songrui Zhang, Bo Chai, Xinli Tian, Zezheng Yang, Yiling Zhang, Peng Li, Xintao Wang

Abstract Background Bone regeneration in individuals with type 2 diabetes mellitus (T2DM) is significantly impaired, even when autologous bone grafts are used. However, previous studies have failed to elucidate the physiological mechanism, and effective treatments are lacking. This study investigated the underlying mechanisms and developed a targeted therapeutic strategy. Methods We established a femoral condyle defect model in diabetic rats and performed autologous bone grafting. Multiomics sequencing analyses rev …

04.09.2026journal-article

Frontiers in Pediatrics

AutoGluon-based interpretable machine learning for clinical risk stratification of retinopathy of prematurity in very preterm infants

Siyu Chen, Shuyue Deng, Xinyi Liu, Wanting Xu, Wenbin Dong, Linxiao Wan, Lan Kang

Introduction Retinopathy of prematurity (ROP) remains an important cause of preventable visual impairment in preterm infants. Current screening relies primarily on gestational age and birth weight, which may not fully capture the heterogeneous postnatal clinical course of very preterm infants. This study aimed to develop and internally validate an interpretable machine-learning framework using routinely collected clinical variables for clinical-course-based in-hospital ROP risk stratification. Methods A total of 23 …