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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 133

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.09.2026journal-article

Genes

Precision Medicine in Pediatric Nephrology: From Shared Clinical Phenotypes to Genotype-Guided Diagnosis and Management

John Dotis, Nikoleta Printza

Pediatric nephrology is shifting from broad phenotype-based labels toward molecularly defined, genotype-guided diagnosis and management. Childhood kidney disorders are enriched for monogenic causes, yet persistent microscopic hematuria, bilateral kidney cysts, steroid-resistant nephrotic syndrome, and thrombotic microangiopathy may represent shared endpoints of biologically distinct mechanisms. Using these four scenarios, this narrative review illustrates how structured phenotyping, pedigree analysis, biochemical e …

04.09.2026journal-article

Iranian Journal of Medical Ethics and History of Medicine

The Medico-Ethical Foundations of Galen’s Thought

Morteza Hoseinzadeh, Sahar Kavandi

Galen is regarded as one of the most enduring and influential figures in the history of medicine. What distinguishes his intellectual legacy is his ability to integrate three fundamental domains, namely medicine, philosophy, and ethics, into a coherent intellectual system. This study aimed to identify and comprehensively examine the medico-ethical foundations of Galen’s thought by analyzing the impact of philosophical doctrines on the formation of his approach to medicine and ethics. The study was based on a critic …

04.09.2026journal-article

Radioprotection

Longitudinal occupational radiation exposure trends in nuclear medicine personnel: a five-year retrospective dosimetry study in Saudi Arabia

Mohammed A. Jowhari, Mohammed Khalil Saeed, Khader Hawsawi, Yousif Abdallah

Occupational radiation monitoring is essential for protecting nuclear medicine personnel who routinely handle unsealed radionuclides. This retrospective longitudinal study evaluated occupational radiation exposure among nuclear medicine staff at a tertiary care hospital in Najran, southwestern Saudi Arabia, using routine thermoluminescent dosimetry records. Whole-body dosimetry records covered March 2021 to October 2025, while extremity dosimetry records obtained using ring dosimeters covered April 2021 to November …

04.09.2026journal-article

Journal of Community Hospital Internal Medicine Perspectives

Thoracentesis-Related Complications: A Comparison Between Vacuum-Assisted and Manual Aspiration Methods

Nikith Rao, Muhammad S. Naseer, Farrin A. Manian, Woo J. Moon

Thoracentesis is a commonly performed bedside procedure for diagnostic evaluation or symptomatic relief of pleural effusions. Although generally considered low risk, prior studies comparing complication rates between aspiration methods, particularly manual and vacuum-assisted aspiration, have reported mixed results. We therefore compared complication rates between these two methods among patients undergoing ultrasound-guided thoracentesis by a hospitalist-led procedure service at a community teaching hospital. Thor …

04.09.2026journal-article

Medicine

Association of shift work and shift patterns with thyroid function

Zeyu Li, Wenjing Peng, Zhiqiang Liao

This cross-sectional study examined the association between shift work and thyroid function using data from the National Health and Nutrition Examination Survey 2007 to 2010. Weighted univariate and multivariate regression models were applied, with additional subgroup and interaction analyses performed. A total of 3578 participants were included (mean age 41.17 ± 13.31 years). After adjusting for potential confounders, shift workers exhibited significantly higher levels of thyroid-stimulating hormone (TSH) (β = 0.3 …

04.09.2026journal-article

Medicine

Case report

Shuang Li, Junjie Yu, Jilin Wei, Meihua Liang

Rationale: Prader–Willi syndrome (PWS) is a complex genetic disorder that affects multiple systems and results from loss of expression of paternally inherited genes in the 15q11.2–q13 region. It is characterized by severe hypotonia and feeding difficulties during infancy, followed by hyperphagia in later childhood and adolescence, which, without strict control of excessive eating behaviors, ultimately leads to severe obesity associated with type 2 diabetes mellitus. Patient concerns: We present the case of a woman …

04.09.2026journal-article

Medicine

Alzheimer disease and lichen planus

Wenya Huang, Liyuan Xiao

Observational studies suggest an association between lichen planus (LP) and Alzheimer disease (AD), but causality remains unclear due to confounding and reverse causation. In this study, we conducted a bidirectional two-sample Mendelian randomization (MR) analysis using Integrative Epidemiology Unit OpenGWAS database for LP (ID: finn-b-L12_LICHENPLANUS) and AD (ID: ebi-a-GCST90012877). The inverse-variance weighted (IVW) method was used as the primary analysis, complemented by MR-Egger, weighted median, simple mode …

04.09.2026journal-article

Medicine

Global burden of thyroid cancer among women aged 15 to 49 years, 1990–2021

Yu Mao, Yanjun Su

Thyroid cancer disproportionately affects women during their reproductive years, yet global trends, socioeconomic gradients, and health inequalities in this age group remain incompletely characterized. Using Global Burden of Disease Study 2021 estimates, we quantified incidence, prevalence, deaths, and disability-adjusted life years (DALYs) due to thyroid cancer among women aged 15 to 49 years in 204 countries and territories from 1990 to 2021. Temporal patterns were evaluated using estimated annual percentage chan …

04.09.2026journal-article

Medicine

Association between vitamin D deficiency and chronic kidney disease progression

Sayed Yousef Mojtahedi, Mohsen Sedighiyan, Paniz Pourpashang

Background: This systematic review and dose-response meta-analysis aimed to evaluate the association between serum vitamin D status and chronic kidney disease (CKD) progression. Methods: We searched PubMed, Scopus, Web of Science, and Embase for relevant observational and cohort studies published between 1990 and 2024. Eligible studies reported baseline vitamin D levels and CKD progression outcomes. We performed a random-effects meta-analysis to calculate the pooled odds ratio (OR) for CKD progression. A dose-respo …

04.09.2026journal-article

Medicine

Adolescent emotional dysregulation and suicide

Feifei Xu, Sheng Xu

The purpose of this review is to investigate the relationship between emotional dysregulation and adolescent suicide, as well as advancements in assessment and treatment methods. A literature search was conducted using the CINAHL and MEDLINE databases. The database search occurred during the month of December 2022. This article summarizes the commonly used assessment tools for emotional dysregulation in clinical settings, as well as psychological interventions and research advancements in the field. Emotional dysre …

04.09.2026journal-article

Medicine

Association of eight urinary metals and trouble sleeping

Qiong Ma, Jian-Zheng Liu, Xiu-E. Shi, Li-Li Li, Xiao-Wei Feng, Xiang Fan, Mi Fu, Jian-Min Lv

While toxic heavy metals have been linked to sleep disorders, the role of less-studied metals remains unclear. We aimed to explore the associations of 8 urinary metals with trouble sleeping and to identify potential gender-specific patterns. This study included 10,012 adults from the National Health and Nutrition Examination Survey 2005–2018. Urinary concentrations of tungsten, arsenic, thallium, cesium, antimony, molybdenum, cobalt, and cadmium were measured. Trouble sleeping was self-reported. We employed weighte …

04.09.2026journal-article

American Journal of Hospice and Palliative Medicine®

Communication and support needs of dementia care partners at end-of-life

Jordan M. Alpert, Michael B. Rothberg, Michael K. Paasche-Orlow, Ardeshir Z. Hashmi, Silvia Perez-Protto, Jacqueline Fox, Elaine Wittenberg

Background Care partners of people with dementia have many responsibilities, including providing care at end-of-life (EOL). Discussions about EOL are often delayed until late in the course of disease, if they occur at all. Objective Learn about the communication and support that care partners need regarding EOL. Methods We conducted 27 interviews with care partners and analyzed these data using the Information, Motivation, and Behavioral Skills Model. We analyzed interview transcripts to deductively develop a codeb …

04.09.2026journal-article

Journal of Clinical Medicine

External Validation of Clinical Risk Scores and Machine Learning Models for Predicting 30-Day Cardiovascular Risk After Noncardiac Surgery: The PERICARE Study

Aslan Erdoğan, Şeyma Yeşil, Gamze Gençol Akçay, Ufuk Sali Halil, İhsan Demirtaş, Ezgi Alp, Berat Erdem, Fatma Ekici, Tuğba Öztürk, İpek Göker, Mustafacan Kılıçoğlu, Hüseyin Akgün, Yusuf İnci, Utku Uluköksal, Furkan Fatih Yücedağ, Alihan Ayata, Baran Yılmaz, Taylan Akgün, Selim Topçu, Can Yücel Karabay

Background: Machine learning (ML) has emerged as a promising approach for preoperative cardiovascular risk prediction; however, the generalizability of ML models across institutions remains uncertain. Moreover, comprehensive head-to-head comparisons between ML algorithms and established clinical risk scores for predicting 30-day major adverse cardiac events (MACE) are scarce. We therefore evaluated the performance and external transportability of multiple ML models across independent centers and compared their pred …

04.09.2026journal-article

Scandinavian Journal of Surgery

Survival following colorectal cancer resection in nonagenarians: A Swedish nationwide population-based study

Parisa G. Mörlin, Mojgan C. Sifolahzadeh, Maziar Nikberg, Peter Matthiessen, Abbas Chabok

Background and aims: To evaluate survival according to treatment strategy among nonagenarians diagnosed with colorectal cancer in Sweden. Methods: This retrospective population-based register study used data from the Swedish Colorectal Cancer Registry. All patients aged ⩾90 years diagnosed with colorectal cancer in Sweden between 2010 and 2019 were included. Patient demographics, tumour characteristics, treatment data, and perioperative outcomes were analysed. Overall survival and relative survival were assessed. R …

04.09.2026journal-article

Clinical Child Psychology and Psychiatry

Measuring Adolescents’ Situated Recognition of Human Rights in Mental Health: Development and Psychometric Validation of the Know and Act Scale

Felipe Agudelo-Hernández, Mónica Valeria Parra Alarcón, Juan David Vargas Meneses, Cristian David Marín Luna, Ligia Marcela Ochoa Pérez

Background Adolescents’ access to mental health care depends partly on their ability to recognize when rights related to emotional distress, confidentiality, participation, non-discrimination, continuity of care, and support are respected or violated. This study developed and evaluated the Know and Act Scale , a vignette-based instrument designed to assess situated recognition of mental health-related human rights among Colombian adolescents. Methods An instrumental, cross-sectional psychometric study was conducted …

04.09.2026journal-article

Journal of Cataract & Refractive Surgery

Photorefractive Keratectomy in Keratoconus: Long-Term Outcomes from a Pre-Cross-Linking Era Cohort

Gustavo E. Tamayo, Natalia Moros, Eduardo J. Polania-Baron, Claudia Castell, Pilar Vargas

Purpose: To describe long-term visual, refractive, and topographic outcomes after photorefractive keratectomy (PRK) in keratoconus patients treated before corneal cross-linking (CXL) became available. Setting: Single private ophthalmic center in Bogotá, Colombia. Design: Retrospective observational study. Methods: 1,532 archived paper charts from all patients at the practice between 1996 and 2004 were screened. Patients with keratoconus who underwent PRK using multiple excimer laser techniques, with adequate preope …

04.09.2026journal-article

Journal of the Colleges of Medicine of South Africa

The clinical spectrum of adult patients with hypercalcaemia attending a tertiary centre in South Africa

Chalese Einbeck, Annalise E. Zemlin, Mogamat-Yazied Chothia

Background: Hypercalcaemia is associated with significant morbidity and mortality. We described the prevalence, causes, biochemical features, management and in-patient outcomes of adult patients with hypercalcaemia at a South African tertiary centre in the Western Cape province. Methods: We conducted a retrospective cohort study of adult hospitalised and outpatients (≥ 18 years) with hypercalcaemia, defined as an unadjusted total serum calcium > 2.50 mmol/L, at Tygerberg Hospital between 01 January 2023 and 31 Dece …

04.09.2026journal-article

Frontiers in Medicine

Out-of-pocket expenditure on medicine for chronic patients and its economic impact on Indian households: a systematic review and meta-analysis

Deepak Kumar Vaishnav, A. Venkat Raman, Akriti Bansal, Pradeep Nair, Krishna Kharwar

Background Out-of-pocket expenditure (OOPE) on medicines constitutes a substantial component of healthcare spending in India, particularly among patients with chronic diseases requiring continuous treatment. This systematic review and meta-analysis aimed to synthesise evidence on medicine-related OOPE in India and assess its magnitude and variation across disease categories, healthcare settings, and provider sectors. Methods We conducted a systematic review and meta-analysis in accordance with PRISMA 2020 guideline …

04.09.2026journal-article

European Journal of Nuclear Medicine and Molecular Imaging

PSMA PET/CT-guided salvage elective nodal radiotherapy for nodal metastases after radical prostatectomy: a bi-institutional long-term outcome analysis

Samuel M. Vorbach, Thomas Seppi, Giulia Santo, Irene Virgolini, Ute Ganswindt, Michael Keilholz, Sarah Frederike Brose, Jozefina Casuscelli, Konrad Klimek, Rudolf A. Werner, Nina-Sophie Schmidt-Hegemann, Claus Belka, Christian Trapp, Paul Rogowski

Abstract Purpose PSMA PET/CT has transformed the detection of nodal recurrence after radical prostatectomy, yet real-world evidence on long-term outcomes of PSMA PET/CT-guided salvage elective nodal radiotherapy (ENRT) remains limited. This study evaluated oncological outcomes of PSMA PET/CT-guided salvage ENRT in a bi-institutional cohort with extended follow-up. Methods We retrospectively analysed 179 patients who received PSMA PET/CT-based ENRT for nodal recurrence after radical prostatectomy at two tertiary cen …

04.09.2026journal-article

Journal of Abdominal Wall Surgery

Contemporary global practice in dissection and closure techniques for lower abdominal transverse incisions: a cross-sectional survey

Leo R. Brown, Hephzibah Adegoke, Ellen Gardner, Thomas M. Drake, James Lucocq, Artur Zanellato

Purpose To characterise international contemporary practice in dissection and closure of lower abdominal transverse incisions (LATI) across surgical specialties. Methods An open, cross-sectional survey of surgeons with experience of performing LATI independently was conducted using an anonymised online questionnaire disseminated via professional networks. Data were captured pertaining to respondent characteristics, operative techniques for dissection and closure of abdominal layers, and experience with incisional h …

04.09.2026journal-article

Frontiers in Psychiatry

Correlation between treatment-related symptom burden and psychological flexibility in patients with cervical cancer and their combined correlational association with emotional distress

Jiao Ma, Yan Peng, Qin Chen, Xinying He, Haixiang Wang

Objective To explore the correlation between treatment-related symptom burden and psychological flexibility in patients with cervical cancer, as well as the combined correlational association of these two factors with patients’ emotional distress, so as to provide a theoretical basis for formulating targeted psychological intervention strategies in clinical practice. Methods A cross-sectional survey was conducted. A total of 216 patients with cervical cancer who received treatment in our hospital from June 2025 to …

04.09.2026journal-article

Frontiers in Medicine

Short-term postoperative neurocognitive safety and recovery profiles of remimazolam tosilate combined with flumazenil vs. propofol in cirrhotic patients undergoing endoscopic variceal treatment: a randomized controlled trial

Yanjie Chen, Xiangrong Du, Fu Shi, Na Zhu

Background Patients with liver cirrhosis frequently exhibit compromised drug metabolism due to hepatic dysfunction, which significantly increases their susceptibility to postoperative neurological adverse events. This study aimed to evaluate the impact of remimazolam tosilate combined with flumazenil on early postoperative neurocognitive function and recovery quality in cirrhotic patients undergoing endoscopic variceal ligation (EVL) and/or endoscopic variceal sclerotherapy (EVS), so as to provide evidence-based gu …

04.09.2026journal-article

Smart Medicine

Herbal Formula AC591 Protects Against Cisplatin‐Induced Hearing Loss by Inhibiting p53‐Mediated Ferroptosis

Yunhao Wu, Yu Tao, Lin Wei, Qiuping Liu, Jiaxin Liu, Wen Jiang, Weiwei Shi, Peng Cao, Xiaolong Fu, Cheng Cheng

ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers. However, its clinical application is significantly restricted due to its severe ototoxicity. Therefore, identifying protective medications to prevent cisplatin‐induced hearing loss (CIHL) is of paramount importance. Here, we show that AC591, derived from the classical herbal formula “Huangqi Guizhi Wuwu decoction,” exhibits notable protective effects on cisplatin‐induced ototoxicity. Our findings indicate that pre …

04.09.2026journal-article

O Mundo da Saúde

Resultados clínicos do serviço de gerenciamento da terapia medicamentosa ofertado a pessoas com artrite reumatoide

Cristiane de Paula Rezende, Isabela Viana Oliveira, Ana Luíza Mourawad César, Paulo Vitor Rozario da Silva, Hágabo Mathyell Silva, Djenane Ramalho-de-Oliveira, Mariana Martins Gonzaga do Nascimento

O tratamento da artrite reumatoide (AR) requer uma farmacoterapia complexa e de alto custo, e à qual as pessoas possuem baixas taxas de persistência. Nesse contexto, oferecer o serviço de gerenciamento da terapia medicamentosa (GTM) a pessoas com AR é uma iniciativa importante para atender às suas necessidades farmacoterapêuticas e, assim, otimizar seus desfechos de saúde. Nesse contexto, o presente estudo teve como objetivo avaliar os resultados clínicos do serviço de GTM ofertado a pessoas com AR em um ambulatóri …