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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 131

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.09.2026journal-article

African Journal of Primary Health Care & Family Medicine

The lived experiences of caregivers of people with epilepsy in Botswana

Jappy M. Toe, Tebogo T. Mamalelala, Esther I. Ntsayagae

Background: Epilepsy is a common neurological disorder affecting about 50 million people worldwide. Caregivers of people with epilepsy face significant emotional, physical and psychological distress due to the demands of caregiving. Limited resources, stigma and the lack of a proper support system often worsen these challenges. Aim: This study aimed to explore the lived experiences of caregivers of individuals with epilepsy in Botswana. Setting: This study was conducted in Gaborone, the capital city of Botswana, lo …

04.09.2026journal-article

Physics in Medicine & Biology

A deep unrolling network based on cartoon texture decomposition for low-dose CT reconstruction

Tingyue Liu, Zhiguo Gui, Yi Liu, Jinxin Luo, Zhen Sun, Pengcheng Zhang

Abstract Objective. Deep unrolling network, as a promising deep learning approach for low-dose computed tomography (LDCT) reconstruction, can efficiently address the issues of severe noise and artifacts in LDCT imaging. However, most existing methods predominantly unrolled the fidelity term to convolutional neural networks (CNNs) while failing to unroll regularization terms, which inevitably limits the feature capture capability of the network. To further improve the performance of deep unrolling networks, this pap …

04.09.2026journal-article

Perioperative Medicine

Temporal trends in intraoperative hypotension exposure in major non-cardiac surgery: a retrospective cohort analysis

Savan Shah, Ewan McFarlane, Sohail Bampoe, Peter M. Odor

Abstract Background Intraoperative hypotension is a common occurrence during general anaesthesia that has consistently been associated with perioperative organ injury. While international consensus guidelines increasingly advocate for maintaining absolute mean arterial pressure thresholds to mitigate this risk, it remains unclear whether these safety recommendations have translated into measurable changes in routine clinical practice. This study aimed to evaluate temporal trends in the burden of hypotension exposur …

04.09.2026journal-article

Cardiology in Review

Safety and Glycemic Efficacy of Perioperative Liraglutide in Cardiac Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ibrahim Gamal, Mohamed Hamouda Elkasaby, Osama Ewidat, Nuha Riyad, Zahra Sadin, Angad Singh Gill, Mahmoud Nassar, William H. Frishman, Wilbert S. Aronow

Perioperative hyperglycemia in cardiac surgery is associated with wound infection, acute kidney injury, and death, yet the intravenous insulin used to treat it is itself coupled to hypoglycemia. Glucagon-like peptide-1 receptor agonists lower glucose only when glucose is elevated and might therefore separate glycemic control from hypoglycemic risk. We searched PubMed/MEDLINE, Scopus, Web of Science, and CENTRAL through September 2025 for randomized controlled trials of perioperative subcutaneous liraglutide versus …

04.09.2026journal-article

European Spine Journal

The accuracy of navigated vs. robot-assisted pedicle screw placement in spine surgery: a retrospective single-centre comparative study

Ali Mulhem, Lennart Schreiweis, Harald Krenzlin, Jens Conrad, Sven Kantelhardt

Abstract Study design Retrospective comparative cohort study. Introduction Accurate pedicle screw placement is critical for spinal stability and for preventing neurological or vascular injury. This study compared screw-placement accuracy and safety between robot-assisted and navigation-guided pedicle screw implantation and explored differences between intraoperative 3D-fluoroscopy and preoperative CT-based surface-matching registration. Methods We assessed all consecutive patients who underwent robot-assisted or na …

04.09.2026journal-article

Prosthesis

Occlusion in Implant-Supported Fixed Partial Restorations: Biological Basis, Biomechanical Considerations and Clinical Recommendations

Andrea Berzaghi, Tiziano Testori, Riccardo Scaini, Sergio Bortolini

Background/Objectives: The management of occlusion in implant-supported fixed partial restorations (ISFPRs) remains a controversial topic due to the limited availability of high-level clinical evidence and the biomechanical differences between natural teeth and dental implants. The absence of the periodontal ligament and the altered biomechanics of implants have led to the development of specific occlusal concepts. This narrative review provides an up-to-date overview of the biological basis and biomechanical princ …

04.09.2026journal-article

Journal of the Association of Nurses in AIDS Care

Promoting Physical Activity in the Context of Clinical Care for People With HIV and Unhealthy Substance Use in the United States: A Qualitative Study

Colleen Mistler, Christie Idiong, Dini Harsono, Linda S. Pescatello, Lydia A. Barakat, Sydney Kang, Jaimie P. Meyer, E. Jennifer Edelman

Abstract Using qualitative methods, we investigated barriers and facilitators to promoting physical activity in an HIV clinic in New Haven, CT. We conducted focus groups with HIV clinicians/staff ( n = 12) and interviews among people with HIV with unhealthy substance use ( n = 10). Data collection and deductive analysis were guided by the Health Equity Implementation Framework domains. Innovation barriers included lack of evidence-based interventions; facilitators included behavioral strategies and app-based progra …

04.09.2026journal-article

Operative Neurosurgery

Sagittal Deformity Correction With a Schwab 4 Osteotomy and a Large-Footprint Interbody Cage: Radiographic and Patient-Reported Outcomes: Case Series

Esteban Quiceno, Isabelle G. Stockman, Mohamed A. R. Soliman, Hendrick Francois, José Manuel Orenday-Barraza, Ethan Kaiser, Kyungduk Rho, Asham Khan, John Pollina, Jeffrey P. Mullin

BACKGROUND AND OBJECTIVES: Sagittal plane deformities can profoundly affect health-related quality-of-life and patient-reported outcomes. We aimed to present our experience with Schwab 4 osteotomy and explore associated radiographic and patient-reported outcomes. METHODS: We conducted a single-center retrospective review of consecutive patients who underwent surgery for severe adult spinal deformities. Patients were included if they underwent a Schwab 4 osteotomy with a large-footprint cage used at the osteotomy si …

04.09.2026journal-article

Frontiers in Medicine

Case Report: Cross-overlapping multi-purse-string closure of a large gastric wall defect after endoscopic full-thickness resection

Zhiyu Ma, Xuan Bai, Jialong Qi, Qiang Guo, Fan Zhang, Tian He, Zan Zuo

Background Secure endoscopic closure of large gastric full-thickness defects after endoscopic full-thickness resection (EFTR) remains challenging, particularly when the defect is irregular and dedicated closure devices are unavailable or unsuitable. Case presentation A 63-year-old man underwent EFTR for a 4.5-cm gastric body lesion originating from the muscularis propria. Resection created an irregular full-thickness defect of approximately 4 cm. Three nylon loops were independently anchored around the defect margi …

04.09.2026journal-article

Research Connections

Biopsy Proven IgA Nephropathy in a Patient with Leprosy: A Case Report and a Literature Review

Susmin Karki, Asmita Parajuli, Prasanna Karki, Nawris Alhassan, Jagdish Lal, Newton Ashish Shah, Poojan Kaphle

Abstract Introduction Leprosy is a chronic infectious disease that may involve the kidneys through immune-mediated mechanisms, most commonly presenting as amyloidosis or proliferative glomerulonephritis. The clinical coexistence of multibacillary leprosy and mesangioproliferative IgA nephropathy (IgAN) is rarely documented. It remains a diagnostic challenge to determine if such cases represent a specific infection-related phenomenon or a coincidental association of two distinct disease processes. Case Description W …

04.09.2026journal-article

European Journal of Case Reports in Internal Medicine

Adult-onset levodopa-unresponsive parkinsonism as the presenting feature of aromatic l-amino acid decarboxylase deficiency

Matthew Spiteri, Russel Tilney, Edith Said, Malcolm Vella

Introduction: Aromatic L-amino acid decarboxylase is a critical enzyme required for the final step in the synthesis of dopamine and serotonin, two important neurotransmitters. Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive disorder of neurotransmitter biosynthesis caused by pathogenic variants in the dopa decarboxylase (DDC) gene. An absence or decrease of dopamine and serotonin levels may lead to severe motor and neurodevelopmental impairments. It classically presents within th …

04.09.2026journal-article

Pediatric Nephrology

Safety and clinical outcomes of antithrombotic therapy in children and young adults with kidney failure on dialysis: a 10-year single-center retrospective cohort study

C. Federico Moral-Ortega, Yasmine Ghattas, Rachel S. Kronenfeld, Chryso Katsoufis, Wacharee Seeherunvong, Jayanthi Chandar, Carolyn Abitbol, Marissa DeFreitas, Fernando F. Corrales-Medina

Abstract Background Pediatric and young adult patients with kidney failure on dialysis are at increased risk of developing thrombotic events (TE). Antithrombotic therapy in this population is challenging due to a concomitant elevated risk of bleeding and the lack of pediatric and young adult–specific data. Methods We conducted a 10-year single-center retrospective cohort study of patients

04.09.2026journal-article

Journal of Medical Microbiology

Tetracyclines, a timely resurgence or doomed to fail again?

Samuel Fenn, Dimitra Panagiotopoulou, Kim R. Hardie

Graphical Abstract Brief diagrammatic overview of tetracyclines structure, mode of action, side-effects, spectrum of action and administration. Tetracyclines are type II polyketides consisting of four fused rings, with an oxygen-rich ‘non-modifiable’ region required to maintain antimicrobial activity. Tetracyclines target the prokaryotic ribosome by binding the 30S subunit, inhibiting polypeptide elongation. These antimicrobials have a broad spectrum of activity targeting Gram-positive and Gram-negative bacteria al …

04.09.2026journal-article

Regional Anesthesia & Pain Medicine

When gastric point-of-care ultrasound changes management: a research letter

Stephen C Haskins, Yuriy Bronshteyn, Cristian Arzola, Hari Kalagara, David Hardman, Oliver Panzer, Marissa M Weber, Eric Heinz, Jan Boublik, Javier Cubillos, Nadia Hernandez, Joshua Zimmerman, Anahi Perlas

Gastric point-of-care ultrasound (POCUS) is increasingly used to assess aspiration risk, but studies differ in whether ultrasound is used to validate the technique, characterize gastric contents in populations, or guide bedside clinical decisions. We performed a focused secondary analysis of 65 studies from the study-level extraction associated with a previously published ASRA Pain Medicine narrative review to determine how often gastric POCUS studies evaluated or reported changes in management. Studies were catego …

04.09.2026journal-article

Medicine

Effect of a modified soft contact lens combined with a noncontact wide-angle viewing system during vitrectomy

Jintao Xia, Hongbing Zhang, Lina Cheng, Xiaogang Yang

Background: To evaluate the efficacy of a modified soft contact lens (MSCL) in maintaining intraoperative visual clarity and protecting the cornea during vitrectomy using a noncontact wide-angle viewing system. Methods: Patients undergoing pars plana vitrectomy were randomly assigned to a balanced salt solution (BSS) group or an MSCL group. All surgeries were performed with a noncontact wide-angle viewing system. In the BSS group, the cornea was intermittently irrigated with BSS, whereas an MSCL was applied through …

04.09.2026journal-article

Medicine

Search for risks of intravenous chemotherapy-induced severe neutropenia in solid cancers

Na Zhang, Aina He

Chemotherapy-induced neutropenia is a common adverse effect, with severe neutropenia associated with significant morbidity, mortality, and costs that require immediate evaluation and treatment. To identify the risk factors that may predispose adult patients with solid cancers to severe intravenous chemotherapy-induced neutropenia, we conducted a retrospective study. A study was performed by collecting data of solid cancer patients who received intravenous chemotherapy from January 2023 to May 2024 at Shanghai Sixth …

04.09.2026journal-article

Medicine

TabPFN-based explainable machine learning for predicting neonatal hyperbilirubinemia

Yu Zhang, Hui Wang, Liping Zhang

Neonatal hyperbilirubinemia is common in early neonatal life, and delayed recognition of high-risk infants may result in bilirubin-induced neurological injury. Prediction models based on routinely available maternal, perinatal, neonatal, and standardized laboratory variables may support early risk stratification as an adjunct to bilirubin measurement and clinical assessment. This single-center retrospective cohort included 986 neonates admitted between January 1, 2016, and March 1, 2026. The hemolytic-disease varia …

04.09.2026journal-article

Journal of Community Hospital Internal Medicine Perspectives

Can Peripheral Angiography Be Safely Performed in Patients with Chronic Renal Insufficiency Without Significant Risk of Contrast-Associated Renal Injury in Outpatient Settings?

Mubashar Choudry, Artem Shmelev, 0. Pierce Sebastian, Noor-E-Fatima Khan, Aleezay Farhat, Donald Wilkerson

Contrast-associated acute kidney injury (CA-AKI) is a known complication following coronary angiographic procedures using iodinated contrast media (ICM). The risk of CA-AKI is multifactorial, dependent largely on estimated glomerular filtration rates. The most important and accepted hospital-based preventive strategy involves both a reduction of iodinated contrast and multi-hour pre- and post-intervention normal saline hydration. Because of time constraints, neither ambulatory surgical centers (ASC), nor outpatient …

04.09.2026journal-article

American Journal of Clinical and Experimental Medicine

Laboratory Resistance to Antiplatelet Therapy as Part of Secondary Prevention of Ischemic Stroke in a Young Patient (Clinical Case)

Batenkova Yurevna, Volkova Ivanovna

In recent years, the incidence of ischemic strokes in young people worldwide has been increasing, leading to early disability, loss of work capacity, and reduced quality of life. Platelets play an active role in the pathogenesis of ischemic stroke. The main drugs for secondary prevention of ischemic stroke are acetylsalicylic acid (ASA) and clopidogrel (CL). ASA inhibits cyclooxygenase-1 (COX-1), which prevents the production of thromboxane A2 (TXA2), thereby inhibiting platelets, while CL acts by inhibiting ADP, w …

04.09.2026journal-article

Innovative Medicine of Kuban

Experience with Augmented Reality Technology in the Removal of Foreign Bodies Following Combat-Related Penetrating Brain Injury

Sh. Kh. Gizatullin, A. Yu. Kokoreva, Z. Sh. Aliev

Background: Advances in modern military technology have resulted in an increased incidence of severe combat-related traumatic brain injuries. Penetrating cranial and brain injuries affect both military personnel and civilians, highlighting their significant medical and societal impact. Such injuries may result in severe neurological deficits and profound disability, while secondary complications may further exacerbate the patient’s condition and increase the risk of mortality. The management of retained foreign bod …

04.09.2026journal-article

Journal of Clinical and Translational Research

Myokines as mediators of muscle–brain crosstalk: Implications for neuroplasticity and neurodegenerative diseases

Marco Machado, Flavio Bachini, Greziene S. Silva, Fabiana P.C. Ramos, Alex Itaborahy

Background: Skeletal muscle is increasingly recognized as an endocrine organ that releases bioactive factors, termed myokines, capable of mediating inter-organ communication, including signaling to the brain. Aim: To summarize current evidence on key myokines involved in muscle–brain crosstalk and their potential roles in neuroplasticity, cognition, and neurodegenerative diseases. Methods: This narrative review synthesizes findings from experimental and clinical studies addressing exercise-induced myokines, their i …

04.09.2026journal-article

Ceramics

The Effect of Different Types of Surface Treatment on the Strength of the Bond Between Veneering Ceramic and Titanium

Leszek Klimek, Michał Wilk, Beata Śmielak

Prosthetic restorations made of titanium and its alloys are often veneered with ceramics. While Co-Cr or Ni-Cr alloys are subjected to high-temperature oxidation before ceramic application, this is not possible for titanium due to its high reactivity; hence, the resulting layers are thick, porous, and have poor adhesion. An alternative method for obtaining an oxide layer is anodic oxidation, or anodization. This paper presents the shear strength of the titanium–ceramic bond after different anodization variants. The …

04.09.2026journal-article

Frontiers in Medicine

Intracanal bridging ossification after lumbar decompression: a case report and imaging analysis of postoperative bone regrowth

Yudong Fu, Wenhui Zhu, Bifeng Fu, Pengtao Huang, Jinchang Han, Dan Xiao, Wenguang Han, Peng Xu, Jingjing Xue, Xiaoqing Zhang

Postoperative bone regeneration following lumbar decompression is an important factor affecting long-term clinical outcomes. However, bridging ossification between the laminectomy defect and the posterior vertebral body margin has rarely been reported, and its imaging characteristics and underlying mechanisms remain poorly understood. Here, we report a case of bridging ossification following lumbar decompression and discuss its possible mechanisms and imaging manifestations based on the relevant literature. A patie …

04.09.2026journal-article

Basic & Clinical Pharmacology & Toxicology

Fluoride as a Modifier of Metallome Homeostasis: A Systematic Review of Animal Studies

Natalia Macedo‐Ribeiro, Jonas Tostes‐Figueiredo, Davi da Silva Barbirato, Isabel Maria Porto, Eliude Barbosa Gomes, Erico Marlon Moraes Flores, Marília Afonso Rabelo Buzalaf, Fernando Barbosa, Raquel Fernanda Gerlach

ABSTRACT Fluoride is widely used for caries prevention due to its effects on mineralized tissues, yet its potential role as a modifier of systemic metal homeostasis remains insufficiently explored. This systematic review synthesizes preclinical evidence on the association between fluoride exposure and changes in metal and semi‐metal concentrations across biological matrices. A comprehensive search strategy was conducted across major databases without language or date restrictions, following SyRF, CAMARADES and PRIS …