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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 123

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Dental Medicine

A novel image-based algorithm to support future remote assessment of chewing function

Dawn Branley-Bell, Richard Brown, Elias Obreque-Sepúlveda, Claire McGrogan, Helen Cartner, Elhassan Mohamed, Chee Siang Ang, Robert Pellegrino

Background Chewing difficulty is associated with poorer physical and mental health. Objective measurement of chewing function is currently limited to methods that require specialist lab equipment (for example lab-based manipulation or comminution tests). A remote method for estimating chewing-related metrics would support the development of accessible and scalable means of detecting and monitoring chewing-related health issues. Method This paper details initial work on developing a novel smartphone-based, image-ana …

03.09.2026journal-article

Frontiers in Neuroscience

Multimodal neuroimaging fusion in presurgical evaluation of drug-resistant epilepsy: current evidence, clinical integration, and future directions

Yuying Zhao, Mingli Wang, Bo Shen, Wei Luo

Approximately 30% of patients with epilepsy are drug-resistant, and for many of them surgical resection of the epileptogenic zone (EZ) offers the best chance of seizure freedom. Because the EZ cannot be measured directly by any single test, it must be inferred from the convergence of complementary imaging markers, and multimodal neuroimaging fusion has therefore become central to modern presurgical evaluation. This critical narrative review examines what each modality—structural MRI, [18F]FDG-PET, ictal SPECT/SISCO …

03.09.2026journal-article

Frontiers in Endocrinology

Artificial intelligence in obesity management: clinical evidence, translational gaps, and implementation priorities—a structured narrative review

Wenneng Liu, Jian Zhao, Dan Zhang, Chun Dang, Yaoheng Lu, Xiao Du

Obesity is a chronic, relapsing disease that requires long-term lifestyle treatment, pharmacotherapy, and metabolic and bariatric surgery. Artificial intelligence (AI) is increasingly being studied across these pathways, but its clinical readiness varies substantially. This Scale for the Assessment of Narrative Review Articles (SANRA)-informed structured narrative review searched PubMed/MEDLINE, Embase, Scopus, ScienceDirect, and Google Scholar through 1 June 2026, primarily for literature published since 2015, wit …

03.09.2026journal-article

Frontiers in Cellular and Infection Microbiology

Diagnostic accuracy of recombinase polymerase amplification-based assays for mosquito-borne virus detection in clinical samples: a systematic review and meta-analysis

Yonghui Gao, Jihong Chen

Background Mosquito-borne viral diseases pose an important public health threat due to their frequent outbreaks, similar early clinical manifestations, and potential for rapid transmission. Conventional diagnostic methods, such as virus isolation, serological assays and RT-qPCR, are reliable but may be limited by long turnaround time, cross-reactivity, laboratory equipment requirements and trained operators. Recombinase polymerase amplification (RPA)-based methods have emerged as promising tools for rapid detection …

03.09.2026journal-article

Frontiers in Dental Medicine

Making periodontal risk visible: the role of artificial intelligence in recall adherence

Prajakta Karkare

Supportive periodontal care is essential for maintaining periodontal stability after active therapy, yet adherence to periodontal maintenance remains difficult. Once bleeding, halitosis or other presenting concerns improve, some patients may interpret the disease as resolved and the maintenance visit as “just a clean.” This Perspective uses the intention–behaviour gap to examine behavioural, financial and health-literacy barriers to continued supportive care. It then considers a narrower, testable hypothesis: artif …

03.09.2026journal-article

Frontiers in Medicine

PD-1/PD-L1 inhibitors combined with chemotherapy as first-line treatment for advanced biliary tract cancer: a systematic review and meta-analysis

Hongye Geng, Chengyuan Lu, Shuling Wang, Lijuan Tian

Objective To systematically evaluate the efficacy and safety of PD-1/PD-L1 inhibitors plus chemotherapy as first-line treatment for advanced biliary tract cancer (BTC). Methods PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases were searched for RCTs and retrospective studies. Meta-analysis was performed using R 4.6.1 software with the meta (v8.5–0) and metafor (v5.0–1) packages. The full R code and datasets are provided in the supplementary material to ensure reproducibility. Result …

03.09.2026journal-article

Frontiers in Medicine

Water awareness and bioethical perspectives among medical students at Mersin University Faculty of Medicine: an analytical cross-sectional study comparing academic-stage groups

Selda Okuyaz, Oya Ögenler

Background The escalating environmental crisis underscores water as a vital bioethical responsibility and public health determinant. Accordingly, water consumption, sustainability, and related ethical responsibilities are relevant topics in medical education. Objective This study aimed to compare water-consumption behaviours, awareness, knowledge, and attitudes toward water use and water-related ethics between Year 3 and Year 6 medical students. Methods This analytical cross-sectional study was conducted at Mersin …

03.09.2026journal-article

Frontiers in Oncology

Comparison of patient-reported outcomes and healthcare utilization between metastatic colorectal cancer patients receiving systemic therapy with or without concurrent palliative care support: a retrospective cohort study

Xiaoli Liu, Fangtuan Wu, Lunlan Li

Background Patients with metastatic colorectal cancer (mCRC) experience substantial symptom burden, yet evidence on the integration of specialist palliative care (PC) in real-world settings remains limited. We assessed the impact of concurrent PC on patient-reported outcomes and healthcare utilization. Objective To evaluate the impact of integrating professional palliative care (PC) with standard systemic therapy on patient-reported outcomes, medical resource utilization, and overall survival (OS) in metastatic col …

03.09.2026journal-article

Archives of Current Research International

Artificial Intelligence Across the Clinical Microbiology Diagnostic Workflow: A Critical Appraisal of Applications, Implementation Challenges and Research Priorities

Adaora Nkiruka Ofole, Dorcas Ayanru

Background and Significance: Clinical microbiology laboratories occupy a decisive position in the management of infection and in the containment of antimicrobial resistance, yet they face rising specimen volumes, contracting specialist workforces and persistent dependence on subjective visual interpretation. Artificial intelligence, and in particular supervised machine learning applied to images, mass spectra, genomes and structured laboratory data, has been proposed as a means of relieving these pressures. Purpose …

03.09.2026journal-article

BMC Cancer

Towards a universal ovarian cancer biomarker model: clinical validation of Trx1 and CA125 dual strategy

Mi A Park, Songhak Kim, Xiaoguang Yang, Jong Am Song, Geon Woo Lee, Heon Jong Yoo, Soyoung Kim, Kyoung Hoon Suh, Young Bok Ko

Abstract Background Ovarian cancer is the fifth leading cause of cancer-related mortality in women, with early detection being critical for improving patient outcomes. Current diagnostic biomarkers, including Cancer antigen 125 (CA125), human epididymis protein 4 (HE4), and their combined Risk of Ovarian Malignancy Algorithm (ROMA), exhibit limited sensitivity and specificity, particularly in early-stage disease and premenopausal women. Thioredoxin-1 (Trx1) has emerged as a potential complementary biomarker. This e …

03.09.2026journal-article

Current Opinion in Otolaryngology & Head & Neck Surgery

A translational framework for early-phase inner-ear gene therapy: clinical trial design, regulatory strategy, and ethical considerations

Emma C. Dunn, Spencer H. Short, Ravi N. Samy

Purpose of review Hereditary hearing loss has historically been approached as a diagnostic category rather than a therapeutically modifiable disease. Recent advances in molecular genetics, cochlear gene delivery, and first-in-human clinical trials are changing that. This review summarizes contemporary progress in the genetics of hearing loss, with emphasis on emerging gene-based therapies, clinical trial design, regulatory and ethical considerations, and practical implications for otolaryngologists as biologic trea …

03.09.2026journal-article

JAMA Otolaryngology–Head & Neck Surgery

Compartment-Specific Recurrence in Medullary Thyroid Cancer

Young-Ji Seo, Kelsey N. Larios, Yifan V. Mao, Yehia K. Elkersh, Bryce England, Elena G. Hughes, Alexandra N. Lim, Jiyoon Kim, Masha J. Livhits, Michael W. Yeh, Trevor E. Angell, Q. Lina Hu-Bianco, Denise Lee, James X. Wu

Importance Total thyroidectomy with bilateral central neck dissection is recommended for medullary thyroid carcinoma (MTC), even in patients without clinical nodal involvement. However, the role of contralateral prophylactic central neck dissection (pCND) remains debated, leading to variations in practice. Objective To evaluate the outcomes of nodal dissection in compartment-specific recurrence in patients undergoing surgical treatment for MTC, including a subgroup analysis of patients with preoperative clinically …

03.09.2026journal-article

JAMA Otolaryngology–Head & Neck Surgery

Persistent Oral Erosions in a 13-Year-Old Male

Siqi Li, Xu Wang, Zhimin Yan

A 13-year-old boy presented to the oral medicine clinic with a 3-year history of oral erosions resistant to treatment with topical steroids and mouthwashes. What is your diagnosis?

03.09.2026journal-article

Scientific Reports

Genomic and epidemiological comparative analysis of clinical Campylobacter isolates from public and private healthcare centers in Santiago, Chile

Dona Benadof, Mirta I. Acuña-Ávila, Mireya Ahumada, Lorena Porte, Thomas Weitzel, Alfonso Fernández, Gabriel Cavada, Christopher Grim, Narjol González-Escalona, Carlos J Blondel, Assaf Katz, Verónica Bravo

Abstract Campylobacteriosis remains underestimated in Latin America due to limited surveillance and diagnostic capacity. In this context, a comparison was made of clinical Campylobacter strains from two distinct healthcare settings in Santiago, Chile: a public pediatric hospital and a private tertiary clinic. Through genomic analysis, host-source attribution was observed to vary across socioeconomic profiles: poultry-associated lineages (such as ST-353 and ST-443 complexes) were, as expected, frequently identified …

03.09.2026journal-article

Journal of Occupational Health

Applicability of Infrared Thermography in Occupational Health for Multidisciplinary Clinical Decision-Making: A Systematic Review with Narrative Synthesis

Marta Regina Cezar-Vaz, Aline da Rosa Pizarro, Joice Simionato Vettorello, Gabriela Laudares Albuquerque de Oliveira, Sérgio Martin Gonzalez Montaño, Clarice Alves Bonow

Abstract Objectives To identify and synthesize evidence on the applications of infrared thermography in the assessment of work-related conditions and to examine its contribution as a non-invasive, adjunctive, and complementary tool to support multidisciplinary clinical assessment and decision-making in occupational health. Methods A systematic review with narrative synthesis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 statement and was registered in the International Prospec …

03.09.2026journal-article

Measurement Science and Technology

A multi-prototype structure constrained class-incremental method for Compound Fault Diagnosis of rolling bearings

Mingrui Wang, Bin Liu, Jiuzheng Ji, Changfeng Yan, xingxiang Zhang, Wang Yi

Abstract Rolling bearing Compound Fault Diagnosis (CFD) is constrained by several factors in industrial environments, including the staged emergence of fault classes, limited sample, and boundary ambiguity among highly correlated fault classes. Traditional diagnostic models are poorly aligned with continuous class-incremental monitoring. To address these problems, a structured multi-prototype diagnosis method is proposed within a class-incremental learning (CIL) framework. Multi-prototype representations are constr …

03.09.2026journal-article

Journal of Behavioral Medicine

Examining relationships between delay and probability discounting and perceived stress in a high-income online sample

Mary J. King, Michelle Rockwell, John Epling, Jeffrey S. Stein

Abstract Previous studies have shown a positive association between perceived stress and delay discounting (DD; devaluation of a consequence as a function of its delay); individuals experiencing high levels of stress tend to prefer smaller, immediate rewards over larger, delayed rewards. However, the link between perceived stress and DD may be confounded by their mutual and well-documented association with socioeconomic disadvantage (e.g., low income, scarcity). Moreover, few studies have examined the association b …

03.09.2026journal-article

JPGN Reports

Referral patterns and patient characteristics in pediatric feeding disorder care at a multidisciplinary outpatient clinic

Edward Tannenbaum, Riad Rahhal, Linda Cooper‐Brown, Willow Cover, Adam Vaske, Dina Al‐Zubeidi

Abstract Objectives Pediatric feeding disorders (PFDs) are increasingly prevalent in the United States. Limited research has examined referral characteristics for outpatient feeding programs. This study analyzes patient referral characteristics based on referral patterns, patient demographics, and treatment interventions. Methods A retrospective cohort study was conducted of pediatric patients evaluated in a multidisciplinary outpatient feeding clinic at a tertiary pediatric academic institution from 2021 to 2024. …

03.09.2026journal-article

HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery

Plate Versus Nail Fixation in Periprosthetic Distal Femur Fractures: An Updated Systematic Review and Meta-Analysis

Tejas Subramanian, Sereen Halayqeh, Michael Mazzucco, Michael J. Cahill, Jennifer Eurich, Elizabeth B. Gausden, Brianna Fram, Mary Kate Erdman, Anthony Christiano, Gregory Schimizzi

Background: Periprosthetic distal femur fractures (PDFFs) are increasing in frequency with the rise in primary total knee arthroplasty in an aging global population. Optimal surgical fixation remains controversial, with both plate and nail constructs widely utilized. Purposes: We sought to compare clinical and radiographic outcomes between plate and intramedullary nail fixation for PDFFs. Methods: A systematic review and meta-analysis were conducted according to Preferred Reporting Items for Systematic Reviews and …

03.09.2026journal-article

Bioengineering

Patient-Reported Knee Function Versus Star Excursion Balance Performance as Correlates of Psychological Return-to-Sport Readiness After Anterior Cruciate Ligament Reconstruction

Ryan T. Halvorson, Aidan Foley, Hayden Sampson, Cameron Nosrat, Drew A. Lansdown, Brian T. Feeley, Jeannie F. Bailey

Background: Psychological readiness, quantified by the Anterior Cruciate Ligament Return to Sport after Injury (ACL-RSI) scale, is one of the most consistent correlates of return-to-sport success following ACL reconstruction. Whether psychological readiness reflects an independent construct or is related to measured functional performance is not known. Purpose: To evaluate the associations between patient-perceived knee function and objective performance on a functional task, as quantified by traditional scoring, k …

03.09.2026journal-article

Frontiers in Human Neuroscience

The association between nonverbal fluency and anomia treatment outcomes in people with post-stroke aphasia

Deena Schwen Blackett, Victoria A. Diedrichs, Alexandra Zezinka Durfee, Courtney C. Jewell, Stacy M. Harnish

Introduction Many people with aphasia experience concomitant executive functioning deficits, and the literature supports a role of executive functioning in treatment response. However, the optimal executive functioning assessment for measuring this impact is unclear, as is the extent to which outcomes (e.g., acquisition, generalization) may be impacted differently. The present retrospective study aimed to determine the degree to which nonverbal fluency, one measure of executive functioning with minimal language dem …

03.09.2026journal-article

Nutrients

Unmetabolized Folic Acid: Biology, Epidemiology, and Clinical Consequences: A Systematic Review

Richard E. Frye, Daniel A. Rossignol

Background: Mandatory folic acid (FA) fortification prevents neural tube defects but generates unmetabolized folic acid (UMFA) in blood, because hepatic dihydrofolate reductase (DHFR) reduces FA only slowly. Whether UMFA itself, as distinct from high total folate, carries biological consequences is unresolved. Methods: We systematically searched six databases (January 1995–May 2026; PROSPERO CRD420261407616) and included 65 publications describing 61 unique primary studies, yielding 71 analytic contributions (15 me …

03.09.2026journal-article

British Journal of Sports Medicine

Prevalence and cardiac outcomes of T wave inversions in high school athletes: an analysis of 15 years of preparticipation screening ECGs

Zachary P Morehouse, Dermot M Phelan, David E Price

Objective To characterise the prevalence, distribution pattern and clinical relevance of T wave inversion (TWI) on a screening preparticipation 12-lead ECG in high school athletes. Methods A retrospective cohort study analysed ECGs from athletes screened between 2010 and 2025 during a preparticipation event. Athletes with TWI in ≥2 contiguous leads were included. Longitudinal cardiac outcomes were assessed via electronic health records, semistructured interviews and extensive media and death registries review. Resu …