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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
10.08.2026journal-article

Frontiers in Medicine

Impaired peripheral perfusion during anesthesia is associated with postoperative delirium in older patients undergoing minimally invasive colorectal surgery: a retrospective observational study

Yu Matsumoto, Shohei Nakatani, Tomomi Yamada, Takeshi Yoshida

Introduction Postoperative delirium (POD) is a frequent postoperative complication in older patients and is associated with poor outcomes. Mean arterial pressure may not adequately reflect microcirculatory perfusion during anesthesia, and the perfusion index (PI), derived from pulse oximetry, is a promising noninvasive surrogate. This study aimed to investigate the association of intraoperative PI with POD in older adults undergoing minimally invasive colorectal surgery. Methods This retrospective observational stu …

10.08.2026journal-article

The Gerontologist

Effectiveness of Mind–Body Therapies for Sleep Disturbance in Older Adults: A Network Meta-Analysis

Haoyu Yang, Zhongli Wang, Fanghua Wang, Jianbang Su, Zhilin Gu, Yingying Liao, Xiaoyu Liang, Zhenhua Xu

Abstract Background and Objectives Mind–body therapies are increasingly used to improve sleep quality in older adults with sleep disturbance. Although previous studies have explored the effects of mind–body therapies, it remains necessary to determine which interventions are most effective and comprehensively evaluate their comparative effects. Research Design and Methods We conducted a systematic search across PubMed, Embase, the Cochrane Central Register of Controlled Trials, and the Web of Science from their inc …

10.08.2026journal-article

International Journal of Nursing Knowledge

NANDA-I, NIC, NOC for Successful Aging in Older Adults with Risk for Imbalance Blood Pressure: Cross-Mapping

Ricardo Costa da Silva, Clarissa Santos de Lima Araujo, Agueda Maria Ruiz Zimmer Cavalcante

Background Global demographic shifts necessitate effective health management for older adults, with blood pressure variability indicating early adverse outcomes. Nurses require theory-guided care for optimal blood pressure management. This study aims to integrate NANDA-I, Nursing Interventions Classification (NIC), and Nursing Outcomes Classification (NOC) to support care for older adults diagnosed with “Risk for imbalanced blood pressure” from the perspective of the Multidimensional Model of Successful Aging (MMSA …

10.08.2026journal-article

Journal of Clinical Medicine

Impact of Preoperative Waiting Time on Intraoperative Blood Transfusion in Older Patients with Hip Fracture: A Retrospective Cohort Study

Neng-Jun Wang, Wei-Song Zhang, Lin Liu, Bin-Fei Zhang

Objective: To explore the associations of preoperative waiting time with the incidence of intraoperative blood transfusion and transfusion volume among older patients with hip fracture, to inform perioperative blood management and optimize surgical timing. Methods: Older patients aged ≥65 years who underwent hip fracture surgery at a tertiary trauma center in Northwest China between 1 January 2015 and 30 September 2019 were included. The primary exposure variable was preoperative waiting time. The outcome indicator …

10.08.2026journal-article

Nicotine & Tobacco Research

Early cigarette smoking reduction and longer-term smoking abstinence in a randomized placebo-controlled e-cigarette trial among people who smoke with no plans to quit

Sitasnu Dahal, Jessica Yingst, Laraib Mazhar, Caroline O Cobb, Jonathan Foulds

Abstract Introduction Evidence from nicotine replacement therapy (NRT) trials for smoking reduction suggests that early reductions in cigarette consumption are associated with long-term smoking abstinence among individuals not initially planning to quit. Whether similar associations exist in smoking reduction trials using electronic cigarettes (e-cigarettes) remains unclear. Methods We conducted an exploratory analysis of a placebo-controlled smoking reduction trial among adults (N=520) who smoked ≥10 cigarettes pe …

10.08.2026journal-article

International Journal of Pharmacy Practice

Recruitment and retention of older people with dementia in clinical trials focused on evaluating the pharmacological management of the cognitive symptoms of dementia: a scoping review

Bara’a Shawaqfeh, Carmel M Hughes, Bernadette McGuinness, Heather E Barry

Abstract Objective To investigate recruitment and retention of older people with dementia in clinical trials focused on evaluating pharmacological interventions for the treatment of cognitive symptoms of dementia. Methods A scoping review conducted using Joanna Briggs Institute methodological guidance. A systematic search of five databases and the International Clinical Trials Registry Platform was conducted from inception to July 2023, and updated in January 2025. Randomised controlled trials of any type in Englis …

10.08.2026journal-article

Processes

Thermal Aging of Aerospace Electro-Hydrostatic Actuator (EHA) Motor Insulation Systems

Yunci Qing, Dongdong Zhao, Dongtao Wu, Guangcai Hu, Peng Wang, Quan Zhao

During the entire service cycle, the Electro-Hydrostatic Actuators (EHAs) are subjected to multi-physical stresses, including coupling effects, including high temperatures, severe temperature variation, and high-frequency pulses. These stresses not only act on the mechanical structures but also continuously degrade the dielectric properties and mechanical strength of the insulation materials, with long-term accumulation potentially leading to deterioration in insulation performance. Consequently, whether the insula …

10.08.2026journal-article

Swiss Archives of Neurology, Psychiatry and Psychotherapy

Geropsychosis: A Biophysical Framework for Understanding Psychiatric Symptoms as Accelerated Aging Pathologies

Nicholaus Nelson-Goedert

The geropsychosis hypothesis proposes that anxiety, mood, psychotic, and neurocognitive disorders may share a common biophysical origin with aging itself, rather than arising from wholly disparate pathological routes in many instances. Specifically, we postulate that these conditions may emerge from the bioaccumulation of metals, advanced glycation end products (AGEs), advanced lipoxidation end products (ALEs), and their hybrid complexes in post-pubescent individuals. Such inputs may drive self-reinforcing molecula …

12.08.2026journal-article

Sociology Study

Food Insecurity among Unsheltered Homeless People in Fresno, California, with an Emphasis on the Role of Drugs and Other Substances, Disease/Illness, Sleeping Patterns, and Food Consumption. II. A Qualitative Study

Helmut Kloos, Ben Matson

The objective of this study is to examine the role of substance use, disease and illness, inadequate sleep, and 24-hour dietary patterns in food insecurity in Fresno’s unsheltered homeless population. We conducted 201 semi-structured interviews and 32 in-depth interviews, and made direct observations of people’s behavior and circumstances. Triangulation of the information from these three methods ensured its reliability and credibility. We employed an inductive thematic analysis, which enabled us to identify, analy …

10.08.2026journal-article

BMC Geriatrics

Older adults’ participation and experiences in design thinking for AI-driven assistive technology: a scoping review

Dhika Dharmansyah, Laili Rahayuwati, Iqbal Pramukti, Kuswandewi Mutyara

Abstract Background Population ageing and the rapid integration of artificial intelligence (AI) into assistive technologies have created a need to engage older adults as active partners in technology design. AI-driven assistive technologies are frequently developed with limited older-adult involvement, a pattern associated with low adoption, poor fit with daily routines, and the reinforcement of ageist assumptions about older adults as passive recipients of care. Design thinking (DT)—an empathy-driven, iterative, h …

10.08.2026journal-article

PLOS Medicine

Risk stratification for significant acute traumatic intracranial hemorrhage in older adults after a ground-level fall: A prospective multicentre cohort study

Xavier Dubucs, Cassandre Even, Jemery Guenezan, Margaux Lagache, Barbara Villoing, Lorraine Pouzet, Marián Sedlák, Radoslav Morochovič, Yann-Érick Claessens, Frédéric Balen, Valérie Boucher, Sandrine Charpentier, Éric Mercier, Marcel Émond

Background Falls among older adults are now the leading cause of traumatic brain injury worldwide. We aimed to identify historical and clinical characteristics including the visible head impact location indicative of significant acute traumatic intracranial hemorrhage in older patients presenting to emergency department with mild traumatic brain injury subsequent to a ground-level fall. Methods and findings We conducted a multicentre prospective cohort study across five university-affiliated emergency departments o …

10.08.2026journal-article

The Journal of the Astronautical Sciences

Assessment of Aging Effects through Remote Sensing Using Color Photometry

Elena Plis, Gregory Badura, Sergey Plis, Yuliya Kuznetsova, Noah Lewis, Jainisha Shah, Zachary Gibson, Ryan Hoffmann

Abstract Accurately characterizing spacecraft materials and the effects of aging is essential for space situational awareness. This study explores the use of a color index taxonomy, developed from laboratory data, as a tool for distinguishing satellite materials based on their optical signatures. The approach extends this taxonomy to include both pristine materials and their irradiated states. Samples from various chemical groups were exposed to high-energy (95 keV) electron irradiation, while their optical propert …

10.08.2026journal-article

Environmental Science & Technology

Correction to “Disaster Preparedness and Perceptions of People who Experienced Water Insecurity: Insights from the Lloyd’s Register Foundation’s World Risk Poll”

Joshua F. Inwald, Wändi Bruine de Bruin, Marc Yaggi

Abstract Water insecurity refers to lacking stable access to enough safe water for drinking and domestic use. To understand the communication needs of individuals who have experienced water insecurity, we analyzed World Risk Poll data from over 125,000 participants across 121 countries. We present three key findings. First, having experienced water insecurity was associated with lower perceived disaster preparedness. Second, participants who had experienced water insecurity trusted disaster information providers sl …

09.08.2026journal-article

Modelling

Collaborative Robust Multi-Objective Optimization of Electrode Air-Flotation Drying Under Equipment Aging Uncertainty

Juchen Hong, Xue Feng, Zhengyun Ren

In the wet-process stage of lithium-ion battery manufacturing, double-sided coating combined with air-flotation drying can reduce repeated drying operations, thereby helping improve production throughput. However, the requirements of air-flotation drying for equipment stability, together with the coupling among process parameters such as temperature, air velocity, and tension, substantially increase the difficulty of process-parameter calibration. As critical components degrade over time, deviations arise between n …

09.08.2026journal-article

Psychology of Music

What Music Do People Use for Mood Regulation?

Catherine Tan, Peter M. C. Harrison

This study seeks to understand what music is used for music mood regulation (MMR). We question how audio features can characterise the music used for different MMR strategies and explore how participant background variables (musical sophistication, sensitivity to musical reward, empathy, and well-being) might predict the use of these strategies, and hence the kinds of music adopted for MMR. Participants ( N = 229) completed an online survey that produced a dataset composed of 5,334 tracks for MMR, their Spotify aud …

09.08.2026journal-article

People and Nature

Balancing forage and fear: How people, environment and predators shape reindeer grazing in the Fennoscandian tundra

Marianne Stoessel, Felicia Wikinger, Regina Lindborg

Abstract The long history of reindeer herding in Fennoscandia has shaped the mountain tundra by influencing its productivity, nutrient and carbon cycling and vegetation structure. By partly limiting shrub expansion, extensive reindeer grazing contributes to ecosystem resilience and helps mitigate climate change effects. Yet, outdoor tourism is discussed as a major pressure that can alter reindeer grazing patterns, with likely consequences cascading onto the tundra plant communities and vegetation structure. To stud …

09.08.2026journal-article

ACS Energy Letters

Material Selection through Accelerated Aging Enables >95% Performance Retention of a Perovskite–Silicon Tandem Solar Cell after 1 Year of Outdoor Monitoring

Helen Bristow, Nathalie Nguyen, Yannick Roujol, Giuliana Giuliano, Diego Di Girolamo, Giuseppe Bengasi, Amandine Boulanger, Vincent Barth, Matthias Demuylder, Marina Foti, Cosimo Gerardi, Noëlla Lemaitre

Abstract In order to ensure that the degradation modes of perovskite–silicon tandem solar cells exacerbated by accelerated aging tests are relevant to those observed under real-world operating conditions, accelerated testing should be developed in line with outdoor monitoring. Here, a short 3-day accelerated aging test under 1 sun equivalent illumination and at open-circuit conditions is validated by outdoor monitoring data. This accelerated test is used to successfully screen perovskite–silicon tandem cell archite …

09.08.2026journal-article

JOR SPINE

Human In Vivo Disc Mechanics in Flexion, Extension, and Diurnal Loading With Aging and Degeneration

Harrah R. Newman, John M. Peloquin, Edward J. Vresilovic, Dawn M. Elliott

ABSTRACT Background The intervertebral disc serves a critical role in spine function, but with aging and degeneration the disc undergoes changes that alter disc mechanics, and degeneration is often implicated in low back pain. The objective of this study was to quantify and evaluate the impact of aging and degeneration on in vivo lumbar disc mechanics across the lifespan. Methods Repeated MRI was performed at a reference state and three loading states: flexion , extension , and diurnal loading for 84 subjects (even …

09.08.2026journal-article

Chemosensors

LIBS-Based Classification of Thermal Aging Levels in High-Voltage Wire Harnesses of New Energy Vehicles Using MAD-RF

Jiapei Cao, Jie Tang, Zhenlin Hu, Jie Ouyang, Ting Luo, Junfei Nie

High-voltage wiring harnesses in new energy vehicles (NEVs) are susceptible to thermal aging in high-temperature environments, whereas conventional assessment methods are difficult to deploy rapidly. This study combines laser-induced breakdown spectroscopy (LIBS) with random forest (RF) classification to assess thermal aging levels in cross-linked polyethylene (XLPE) insulation. Thirteen laboratory-aged XLPE wiring harness samples were prepared, and 100 single-shot spectra were acquired at fresh positions for each …

09.08.2026journal-article

Biomedicines

Associations of Accelerated DNA Methylation Aging Algorithms with Chronic Liver Disease and All-Cause Mortality

Xinyi Zhang, Zhenduo Chen, Zike Cheng, Hui Zhang, Yaqian Xu, Chongyu Ding, Tongyan An, Yulu Gong, Darong Hao, Jinjie Xu, Shuaiyin Chen

Background: Chronic liver disease (CLD) represents a substantial global health challenge, with significant morbidity and mortality worldwide. Biological aging may be involved in CLD-related outcomes, but the associations of diverse DNA methylation (DNAm) aging algorithms with CLD phenotypes and long-term mortality remain incompletely characterized. Methods: Using a US nationally representative cohort, we analyzed 12 DNAm aging algorithms in 2522 adults aged ≥50. CLD was classified into viral, alcohol-related, metab …

09.08.2026journal-article

Sustainability

Digital Economy and Aging-Service Capacity in China: Service Availability Mechanisms and Fiscal-Technology Support Thresholds

Mengqing Wu, Zihao Wu, Fang Bu, Junhe Liu, Jiangao Deng

China’s aging population is placing growing demands on medical care, social protection, community-based provision, and everyday assistance. Using a balanced panel for 31 provincial-level regions over 2014–2023, this study evaluates whether regional digital-economy development is linked to the capacity to meet those demands and how that relationship varies across service and institutional settings. The Digital Economy Index (DEI), Aging-Service Capacity Index (ASC), Daily-Life Service Availability (DLSA), and Health …

09.08.2026journal-article

Healthcare

Association Between Computed-Tomography-Derived Erector Spinae Muscle Characteristics and Swallowing Outcomes in Older Patients with Pneumonia

Yuichi Murakawa, Akira Tamaki, Ryota Matsuzawa, Shinjiro Miyazaki, Koji Fujishima, Tatsuma Hori, Miki Naide, Kenichiro Sakai, Tomoya Ishii

Background/Objectives: Trunk muscle mass and quality may be related to swallowing function; however, it is unclear whether the same trend is observed in older patients with pneumonia. We aimed to determine the impact of the mass and quality of the erector spinae muscles (ESM), measured using chest computed tomography (CT), on swallowing function decline during hospitalization. Methods: The participants were patients hospitalized at Sanuki Municipal Hospital with a diagnosis of pneumonia who underwent pulmonary reha …

09.08.2026journal-article

Longevity Horizon

MCARA: The Centriole as a Fourth Counter in Cellular Aging: A Hypothesis

Jaba Tqemaladze

Cells divide a finite number of times, and the limit is not fully explained by telomeres or mitochondrial damage. This paper proposes that the centriole, the microtubule cylinder at the core of the centrosome, records how many division cycles a cell has survived. The centriole and the primary cilium are two states of a single organelle: in the ciliary state it is short, anchored at the membrane, and receives developmental signals; in the centrosome state the cilium is resorbed and the cell divides. Across successiv …

09.08.2026journal-article

Journal of Gastroenterology and Hepatology

BEAT‐B Study (Behavior, Aspirations, and Treatment Needs): A Mixed‐Methods Study of Patient Values, Preferences, and Barriers to Care Among People Living With Chronic Hepatitis B in South and Southeast Asia

Manya Prasad, Tushar Prabhakar, Priyanka Shenoy, Priyanka Aggarwal, Tawesak Tanwandee, K. C. Sudhamshu, M. Golam Azam, Zaigham Abbas, G. Vaishnavi, Vivekanandan Shanmugam, Bharat Bhushan Rewari, Shiv Kumar Sarin

ABSTRACT Background Chronic hepatitis B (HBV) infections have significant challenges in treatment uptake and adherence due to sociocultural barriers, healthcare system inefficiencies, and economic constraints. The evidence to decision framework highlights the importance of understanding patient values and preferences to align evidence‐based policies with the “treat all” approach. Methods This mixed‐methods study included a cross‐sectional survey in five South Asian countries and qualitative data collection through …