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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
10.08.2026journal-article

Quality in Sport

Deprescribing in Primary Care Patients Aged 65 Years and Older Exemplified by Hypertension, Type 2 Diabetes, and Insomnia: A Literature Review

Zofia Biernacka, Urszula Kacprzak, Mikołaj Celmer, Mateusz Majchrzak, Julia Kossakowska, Marcin Ruszkowski, Norbert Piątkowski

Background. An aging population has become a fact around the world. It is estimated that by 2050, individuals over the age of 65 will constitute more than 56.7% of the European population. Aging involves a series of physiological changes and is a highly variable process among individuals. In elderly patients with hypertension, type 2 diabetes, or insomnia, treatment de-escalation is frequently required. This study identifies challenges physicians encounter in daily practice during the deprescribing process and high …

10.08.2026journal-article

Proceeding Cendekia International Conference Health and Technology

Provision Of Stigm A To People With Hiv/Aids (Odha) In Students In Pati District

Yuli Irnawati, Siti Ni'amah

Negative stigma related to HIV/AIDS is one of the the barrier that faced People living with HIV/AIDS For prevention And treatment disease HIV/AIDS(Wahyuni S & Ronoatmodjo , 2017). Impact from giving negative stigma to PLWHA can cause feeling rejected and isolated so that PLWHA try For covering up their health status . As a result , negative stigma can hinder effort For reach HIV information , HIV testing , treatment , and prevention HIV /AIDS (Boakye &Mavhandu-Mudzusi, 2019). The aim of this study was to determine …

10.08.2026journal-article

The International Conference on Sustainable Economics Management and Accounting Proceeding

POPULATION AGING, ECONOMIC GROWTH, AND HEALTH FINANCING SUSTAINABILITY: EVIDENCE FROM ASEAN-5 COUNTRIES

Afiati Hary Kresnawati, Budi Aji, Diah Setyorini Gunawan, Unik Lestari

This study examines the impact of population aging, economic growth, and investment on public health expenditure within the framework of health financing sustainability in ASEAN-5 countries (Indonesia, Malaysia, Thailand, the Philippines, and Singapore). Using a quantitative approach with panel data from 2009–2023, the analysis employs the Fixed Effects Model (FEM) to control for unobserved heterogeneity across countries. Population aging is proxied by the old-age dependency ratio, economic growth by GDP per capita …

10.08.2026journal-article

Geriatrics

Appropriateness over Numbers: Pharmacological Burden and Scalable Medication Review in Older Adults

Michał Pstrągowski, Dawid Hachlica, Łukasz Izbicki

Polypharmacy in older adults is common, rising and inconsistently defined, and it is widely treated as a problem of how many medicines a person takes. This non-systematic narrative review argues that its harm depends more on the appropriateness of the regimen and the pharmacological burden the regimen imposes, with the number of drugs a partly confounded marker rather than the principal cause. Drawing on evidence published mainly since 2020, it traces the shift from counting medicines to weighting them; the prescri …

10.08.2026journal-article

Psychogeriatrics

Progression to Dementia in Very Late‐Onset Schizophrenia‐Like Psychosis Stratified by A lzheimer's Disease and L ewy Body Disease Biomarkers: A Retrospective Cohort Study

Yuto Satake, Hideki Kanemoto, Daiki Taomoto, Kayo Takeda, Shigeki Katakami, Matasaburo Kobayashi, Keiko Matsunaga, Kayako Isohashi, Takashi Suehiro, Kenji Yoshiyama, Manabu Ikeda

ABSTRACT Background Very late‐onset schizophrenia‐like psychosis (VLOSLP) is clinically heterogeneous, and its relationship with dementia‐related neurodegenerative disease remains unresolved. We examined whether Alzheimer's disease (AD) and Lewy body disease (LBD) biomarker status were associated with dementia progression in VLOSLP. Methods We retrospectively identified patients who visited the University of Osaka Hospital between January 2018 and December 2023 and met criteria for VLOSLP. Twenty‐two participants w …

10.08.2026journal-article

Current Alzheimer Research

Subclinical Atherosclerosis Markers in Alzheimer's and Vascular Dementia: A Cross-Sectional Comparison with Healthy Controls

Aylin Güneşli, Fazirah Hussein

Introduction: Vascular mechanisms are increasingly implicated in the pathophysiology of Alzheimer’s disease and vascular dementia. This study aimed to evaluate the association between subclinical atherosclerosis markers and cognitive performance in patients with Alzheimer’s disease and vascular dementia compared with healthy controls. Methods: This cross-sectional study included 79 patients with Alzheimer’s disease, 69 patients with vascular dementia, and 69 age- and sex-matched controls. Vascular markers were meas …

10.08.2026journal-article

ACS Food Science & Technology

The Prospects for the Application of Optical Probes for Detecting Senescent Cells in Research into Natural Anti-Aging Substances: A Review

Yu Cheng, Yi Jia, Liyi Zhou

Abstract With the intensification of population aging and the rising incidence of chronic diseases posing significant threats to health and longevity, interventions targeting the regulation of aging have garnered increasing attention. Consequently, the development of natural edible substances possessing antiaging properties has become a prominent focus in food research. To meet this demand, the creation of novel visualization assessment methods is paramount. Compared to the limitations of traditional techniques, op …

10.08.2026journal-article

Journal of Intellectual Disabilities

Intellectual disabilities and risk of dementia: A Korean population-based cohort study

Yoo Jin Um, In Young Cho, Hye Yeon Koo, Yong-Moon Mark Park, Kyung Mee Kim, Chung Eun Lee, Kyungdo Han

This retrospective cohort study assessed the risk of all-cause dementia, Alzheimer’s disease (AD), and vascular dementia (VaD) in individuals with intellectual disabilities compared to those without. Using data from the Korean National Disability Registry and National Health Insurance Service, individuals over 40 who underwent health examinations in 2009 were followed until 2020. Cox proportional hazards models estimated hazard ratios (HRs) for dementia outcomes, adjusting for confounders. Over a mean 8-year follow …

10.08.2026journal-article

Oral Diseases

Fractal Analysis of Periodontal Tissues in Geriatric Patients With Different Periodontal Conditions: A Retrospective Study

Dilek Ozkan Sen, Omer Ogutcen, Fatma Ucan Yarkac, Ibrahim Burak Yuksel, Muhammet Emin Arslan, Zeynep Tastan Eroglu

ABSTRACT Objective This study evaluated the relationship between fractal dimension (FD) values and periodontal status in geriatric patients using digital panoramic radiographs. Methodology In this retrospective observational study, 147 elderly individuals were classified as periodontally healthy ( n = 30), gingivitis ( n = 32), Stage I periodontitis ( n = 26), Stage II periodontitis ( n = 14), Stage III periodontitis ( n = 20), and Stage IV periodontitis ( n = 25) according to the 2017 World Workshop Classification …

10.08.2026journal-article

Frontiers in Psychology

Intelligent health management technology use and depressive symptoms among older adults: the serial mediating roles of physical activity and social adaptation

Xiagang Song, Zhenjiang Tian

Objective This study examined the association between intelligent health management technology (IHMT) use and depressive symptoms among older adults in China, focusing on the mediating roles of physical activity and social adaptation. Methods Using data from the 2023 China Longitudinal Aging Social Survey, this cross-sectional study included 10,300 older adults aged 60 years and above. A serial mediation model was estimated using the PROCESS macro (Model 6) in SPSS 25.0. The significance of the indirect effects was …

10.08.2026journal-article

npj Dementia

Ensuring access to Tau-Targeting therapies for MAPT frontotemporal dementia: patient community priorities for regulators and industry

Linde Jacobs, Cure MAPT FTD, Tanya Steel, Barbara Dawson, Barbara Frommell, Annika Roll, Marian Grems

Abstract MAPT Frontotemporal Dementia (FTD) is a rare and devastating neurodegenerative disease caused by genetic mutations leading to tau aggregation. This document outlines seven key requests that Cure MAPT FTD, a nonprofit patient advocacy organization, made on May 23, 2025 in a Patient Listening Session to the U.S. Food and Drug Administration (FDA) regarding clinical trial design and the approval of tau-targeting therapies for MAPT FTD patients. The recommendations were informed by a community survey of 44 pat …

10.08.2026journal-article

Frontiers in Public Health

Parental socioeconomic position, childhood poverty and healthy aging: retrospective and prospective study of six cohorts across 32 wealthy and developing nations

Gindo Tampubolon

Background and aim Children who were poor in wealthy countries have reported worse cognitive, muscle, and mental functions, as well as greater frailty and multimorbidity, in later life. However, it remains unclear whether those who were poor in childhood worldwide fall short of healthy aging, as information on childhood conditions is often unreliable. Here, I present new evidence on the lifecourse shaping of healthy aging among older adults worldwide. Methods Some 80,000 older adults aged 50 and over in 32 wealthy …

10.08.2026journal-article

Frontiers in Neurology

Person-centered non-pharmacological interventions for agitation in dementia: a meta-analysis with subgroup analysis by behavioral subtypes

Ruilong Ye, Mengqing Lin, Lingjun Lei

Objective This meta-analysis aimed to evaluate the overall efficacy of person-centered non-pharmacological interventions for agitation in dementia and to compare treatment effects across behavioral subtypes, specifically physical aggressive agitation, physical non-aggressive agitation, and verbal agitation. Methods A systematic literature search was conducted in PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL) from database inception to March 2026. Randomized controll …

10.08.2026journal-article

The British Journal of Psychiatry

Improving outcomes for people with co-occurring autism and psychosis: from diagnostic overshadowing to system-wide clinical capability

Andrew J. Watson, Kathryn M. Taylor, Demelza Tootill, Vaughan Bell

Summary Individuals with co-occurring autism and psychosis are poorly supported by current psychiatric systems yet commonly present to both autism and psychosis services. Diagnostic overshadowing, fragmented pathways and unadapted interventions drive poorer outcomes. Psychosis services must embed neurodevelopmentally informed assessment, formulation, staff training and routine treatment adaptations to deliver equitable, effective care for this underserved population.

10.08.2026journal-article

AIDS Research and Human Retroviruses

Efficacy and Safety of Albuvirtide Plus Dolutegravir or Dolutegravir/Lamivudine in Hospitalized People with Advanced AIDS: A Retrospective Real-World Study

Huanxia Liu, Yuanhong He, Tongtong Yang, Lin Cai, Yuan Yuan, Chunrong Lv, Shenghua He

Hospitalized people with advanced AIDS require potent, safe antiretroviral therapy (ART) with minimal drug interactions. This real-world retrospective cohort study aims to evaluate the efficacy and safety of albuvirtide (ABT) plus dolutegravir (DTG), with or without lamivudine (3TC), in this vulnerable population. We retrospectively analyzed clinical data from treatment-naïve (TN) and treatment-experienced (TE) hospitalized people with AIDS who received an ABT-based regimen for at least 24 weeks at the Chengdu Publ …

10.08.2026journal-article

Current Alzheimer Research

Dynamic Entropic Mapping of Alzheimer’s Neuropathology: Eyes-Open and Eyes-Closed EEG Biomarkers through Wavelet Entropy Analysis

Yujiao Tong, Guanqun Hu, Lingfeng Liu, Ying Zhang, Nan Jiang, Ying Hou, Meiyun Zhang

Background: Alzheimer’s Disease (AD) is characterized by amyloid-β plaques and tau tangles, while current diagnostic tools are often invasive and costly. Electroencephalography (EEG) offers a non-invasive alternative, with alpha rhythm abnormalities as key features. Impaired alpha reactivity during the transition from Eyes-Closed (EC) to Eyes-Open (EO) reflects early thalamocortical dysfunction. Objective: This study employs EO/EC wavelet entropy analysis to assess neurodynamic features across frequency bands, aimi …

1 Zitationen
10.08.2026journal-article

BMC Medicine

Remission of long-term conditions among adults with multiple long-term conditions in England primary care: A retrospective cohort study of 4.7 million people

Aman Jat, Benjamin D Barton, Rohini Mathur, Beth Stuart, Hilda Hounkpatin, Hajira Dambha-Miller

Abstract Background Multiple long-term conditions (MLTC) are increasingly prevalent among UK adults, yet the extent to which remission of long-term conditions is recorded in routine primary care remains poorly understood. Accurate documentation of remission has implications for clinical management, disease trajectories, and the use of electronic health records in research. Examining remission in the context of MLTC is important because remission in one condition may alter overall disease burden and treatment needs …

10.08.2026journal-article

International Journal of MS Care

Perspectives on End of Life and Medical Assistance in Dying From Saskatchewan People With Multiple Sclerosis

Janine Brown, Katherine B. Knox, Lilian Thorpe, Loralee Herter, Mir Nabila Ashraf, Michael C. Levin, Ilia Poliakov

Background: Medical assistance in dying (MAID) is a legally available option in Canada. Bill C-14 determined initial eligibility requirements (eg, a patient having a reasonably foreseeable natural death), program safeguards, and a definition of who can assess and administer MAID. Subsequently, Bill C-7 removed the requirement that death must be reasonably foreseeable. Saskatchewan’s multiple sclerosis (MS) prevalence rate is among the highest in the world, and some individuals with MS have already accessed MAID. Th …

10.08.2026journal-article

Zamonaviy jamiyat va innovatsiyalar ilmiy-nazariy jurnali

YOSHLARDA HUQUQIY ONG TUSHUNCHALARINI SHAKLLANTIRISHNING IJTIMOIY-PSIXOLOGIK XUSUSIYATLARI

UMIDA OLIM QIZI FAYZIYEVA

This article examines the socio-psychological characteristics of shaping legal consciousness and legal culture among youth, the mechanisms of attitude formation towards laws, and methods for preventing legal nihilism. The paper highlights the role and importance of cognitive, emotional, and behavioral factors in enhancing legal literacy among young people. Furthermore, it analyzes the impact of educational institutions, the family environment, and the digital information space on an individual's legal worldview. Pr …

10.08.2026journal-article

Australian & New Zealand Journal of Psychiatry

Unplanned health service utilisation among people living with cancer and mental health conditions: A retrospective matched case-comparison study in Australia

Ramya Walsan, Reema Harrison, Huah S. Ng, Eng-Siew Koh, Sabe Sabesan, Ashfaq Chauhan, Anita Vandyke, Natalie Taylor, Elizabeth Manias, Tim Badgery-Parker, Rebecca Mitchell

Background: Mental health conditions are associated with inequities across the cancer pathway, yet differences in unplanned health service use remain poorly described. This study examined sociodemographic, clinical and virtual care use factors associated with unplanned health service use among adults living with cancer, with and without mental health conditions. Methods: A retrospective matched case-comparison study was conducted using linked data from three Australian states. Adults aged ⩾ 18 years with cancer wer …

1 Zitationen
10.08.2026journal-article

Journal of the American Geriatrics Society

Comparative Effectiveness, Safety, and Costs of Gabapentinoids in Older Adults With Long‐Term Opioid Use

Kevin T. Pritchard, Chun‐Ting Yang, Qiaoxi Chen, James M. Wilkins, Dae Hyun Kim, Kueiyu Joshua Lin

ABSTRACT Background It is unclear whether managing chronic pain with adjuvant gabapentin versus pregabalin can safely reduce long‐term opioid use among older adults. Our objective was to compare clinical effectiveness, safety, and costs of initiating gabapentin versus pregabalin. Methods We conducted a retrospective cohort study and target trial emulation in a US National sample of 2013–2018 Medicare fee‐for‐service and 2004–2024 Optum's de‐identified Clinformatics Data Mart Database (Optum CDM). Participants inclu …

10.08.2026journal-article

Arthritis Care & Research

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

Michael D. George, George Reed, Matthew D. Kearney, Peter F. Cronholm, Kevin Kane, Jeffrey R. Curtis, Dimitrios A. Pappas, Joel M. Kremer

Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed between 2023 and 2024, capturing demographics, medication safety concerns, and a range of other attitudes. We then identified patients with RA initiating a new biologic o …

10.08.2026journal-article

Asian Journal of Social Health and Behavior

Pupil–galvanic Skin Response Synchrony during Family-centered Visual Reminiscence in Older Adults with Cognitive Impairment: A Proof-of-concept Study

Cheng-Ren Chen, Jung-Ying Hou, Hui-Ching Weng

Abstract Introduction: Subtle changes in attention and emotion characterize early cognitive decline. In Asian elders, where family is central, culturally tailored reminiscence therapy (RT)-inspired visual stimulation may amplify autobiographical engagement. We aimed to determine whether visual–autonomic coupling, assessed through eye-tracking and galvanic skin response (GSR), serves as a sensitive physiological indicator of cognitive vulnerability during family-centered, RT-inspired visual stimulation. Methods: Thi …